Drug target prioritization by perturbed gene expression and network information (Q38816088)

6 September 2017

Drug target prioritization by perturbed gene expression and network information (English)

1 reference

6 September 2017

1 reference

4

Michael Schroeder

1 reference

6 September 2017

3

Carlo Vittorio Cannistraci

1 reference

6 September 2017

Zerrin Isik

1

1 reference

6 September 2017

Christoph Baldow

series ordinal

2

1 reference

6 September 2017

language of work or name

English

0 references

publication date

30 November 2015

1 reference

6 September 2017

1 reference

6 September 2017

5

1 reference

6 September 2017

17417

1 reference

Creative Commons Attribution 4.0 International

6 September 2017

start time

30 November 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

Cytoscape

object named as

Cytoscape

2 references

9 June 2022

https://europepmc.org/search?query=(METHODS:'Cytoscape')

based on heuristic

inferred from PubMed Central ID database lookup

CZ Software Mentions: A large dataset of software mentions in the biomedical literature

exact match

https://scigraph.springernature.com/pub.10.1038/srep17417

0 references

cites work

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Characterization of drug-induced transcriptional modules: towards drug repositioning and functional understanding

9 September 2017

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Drug target prediction and repositioning using an integrated network-based approach

9 September 2017

1 reference

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Finding the targets of a drug by integration of gene expression data with a protein interaction network

9 September 2017

1 reference

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Structure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive review

9 September 2017

1 reference

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Adding protein context to the human protein-protein interaction network to reveal meaningful interactions.

9 September 2017

1 reference

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Peroxisome proliferator-activated receptor γ agonists induce cell cycle arrest through transcriptional regulation of Kruppel-like factor 4 (KLF4)

9 September 2017

1 reference

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STRING v9.1: protein-protein interaction networks, with increased coverage and integration

9 September 2017

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The TissueNet database of human tissue protein-protein interactions

9 September 2017

1 reference

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Iteration method for predicting essential proteins based on orthology and protein-protein interaction networks

9 September 2017

1 reference

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Network-based characterization of drug-regulated genes, drug targets, and toxicity

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4663505

Drug repositioning through incomplete bi-cliques in an integrated drug-target-disease network

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4663505

A new essential protein discovery method based on the integration of protein-protein interaction and gene expression data

9 September 2017

1 reference

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A network flow approach to predict drug targets from microarray data, disease genes and interactome network - case study on prostate cancer

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4663505

STITCH 3: zooming in on protein-chemical interactions

9 September 2017

1 reference

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Therapeutic target database update 2012: a resource for facilitating target-oriented drug discovery.

9 September 2017

1 reference

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Fatty acid binding proteins (FABPs) in prostate, bladder and kidney cancer cell lines and the use of IL-FABP as survival predictor in patients with renal cell carcinoma

9 September 2017

1 reference

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PSICQUIC and PSISCORE: accessing and scoring molecular interactions

9 September 2017

1 reference

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Prognostic value and function of KLF4 in prostate cancer: RNAa and vector-mediated overexpression identify KLF4 as an inhibitor of tumor cell growth and migration

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4663505

Peroxisome proliferator-activated receptor-gamma activation inhibits tumor metastasis by antagonizing Smad3-mediated epithelial-mesenchymal transition

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4663505

Discovering pathways by orienting edges in protein interaction networks

9 September 2017

1 reference

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Pathway databases and tools for their exploitation: benefits, current limitations and challenges

9 September 2017

1 reference

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Integrating large-scale functional genomic data to dissect the complexity of yeast regulatory networks

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4663505

Estimating the size of the human interactome

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4663505

BindingDB: a web-accessible database of experimentally determined protein-ligand binding affinities

9 September 2017

1 reference

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The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease

9 September 2017

1 reference

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Cytoscape: a software environment for integrated models of biomolecular interaction networks

9 September 2017

1 reference

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Summaries of Affymetrix GeneChip probe level data

9 September 2017

1 reference

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Expression pattern of fatty acid-binding proteins in human normal and cancer prostate cells and tissues

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4663505

9 September 2017

The Protein Data Bank

1 reference

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PEDF inhibits IL8 production in prostate cancer cells through PEDF receptor/phospholipase A2 and regulation of NFκB and PPARγ.

9 September 2017

1 reference

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From link-prediction in brain connectomes and protein interactomes to the local-community-paradigm in complex networks

9 September 2017

1 reference

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SPECTRA: An Integrated Knowledge Base for Comparing Tissue and Tumor-Specific PPI Networks in Human.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4663505

Stromal expression of connective tissue growth factor promotes angiogenesis and prostate cancer tumorigenesis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4663505

Centrality analysis methods for biological networks and their application to gene regulatory networks.

14 September 2017

1 reference

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Utility of network integrity methods in therapeutic target identification

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4663505

Drug-target interaction prediction by random walk on the heterogeneous network.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4663505

An introduction to ROC analysis

31 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSREP17417

Peroxisome proliferator-activated receptor gamma inhibits transforming growth factor beta-induced connective tissue growth factor expression in human aortic smooth muscle cells by interfering with Smad3

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26615774

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Drug target validation and identification of secondary drug target effects using DNA microarrays

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26615774

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/SREP17417

1 reference

Dimensions Publication ID

6 September 2017

0 references

1 reference

6 September 2017

1 reference