AR-12 Inhibits Multiple Chaperones Concomitant With Stimulating Autophagosome Formation Collectively Preventing Virus Replication. (Q38770459)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27187154%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

title

AR-12 Inhibits Multiple Chaperones Concomitant With Stimulating Autophagosome Formation Collectively Preventing Virus Replication (English)

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3

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Sina Bavari

5

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Javier González-Gallego

14

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María J. Tuñón

15

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Federico Giovannoni

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author name string

Laurence Booth

1

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1 April 2020

Jane L Roberts

2

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Sarah R Tritsch

4

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St Patrick Reid

6

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Stefan Proniuk

7

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Alexander Zukiwski

8

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Abraham Jacob

9

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Claudia S Sepúlveda

10

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Cybele C García

12

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Elsa Damonte

13

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Paul Dent

16

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publication date

6 June 2016

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Journal of Cellular Physiology

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published in

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volume

231

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issue

10

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page(s)

2286-2302

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Intracellular processing of the human respiratory syncytial virus fusion glycoprotein: amino acid substitutions affecting folding, transport and cleavage

1 April 2020

cites work

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The measles virus (MV) glycoproteins interact with cellular chaperones in the endoplasmic reticulum and MV infection upregulates chaperone expression

21 January 2018

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OSU-03012 suppresses GRP78/BiP expression that causes PERK-dependent increases in tumor cell killing

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Regulation of OSU-03012 toxicity by ER stress proteins and ER stress-inducing drugs

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OSU-03012 and Viagra Treatment Inhibits the Activity of Multiple Chaperone Proteins and Disrupts the Blood-Brain Barrier: Implications for Anti-Cancer Therapies

21 January 2018

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GRP78/BiP/HSPA5/Dna K is a universal therapeutic target for human disease

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Characterization of an HIV-1 Isolate Displaying an Apparent Absence of Virion-Associated Reverse Transcriptase Activity

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dsRNA-dependent protein kinase PKR and its role in stress, signaling and HCV infection

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Ebola virus (EBOV) infection: Therapeutic strategies

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Endoplasmic reticulum (ER) stress induced by a neurovirulent mouse retrovirus is associated with prolonged BiP binding and retention of a viral protein in the ER.

21 January 2018

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OSU-03012, a novel celecoxib derivative, induces reactive oxygen species-related autophagy in hepatocellular carcinoma

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Herpes simplex virus type 2 encodes a heat shock protein homologue with apoptosis regulatory functions

21 January 2018

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BiP and multiple DNAJ molecular chaperones in the endoplasmic reticulum are required for efficient simian virus 40 infection

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Heat shock protein 27 is involved in PCV2 infection in PK-15 cells

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The critical roles of endoplasmic reticulum chaperones and unfolded protein response in tumorigenesis and anticancer therapies

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OSU-03012 stimulates PKR-like endoplasmic reticulum-dependent increases in 70-kDa heat shock protein expression, attenuating its lethal actions in transformed cells

21 January 2018

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21 January 2018

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HSPA5 is an essential host factor for Ebola virus infection

21 January 2018

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GRP78/Dna K Is a Target for Nexavar/Stivarga/Votrient in the Treatment of Human Malignancies, Viral Infections and Bacterial Diseases

21 January 2018

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Selective and transient association of Sendai virus HN glycoprotein with BiP.

21 January 2018

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Nexavar/Stivarga and viagra interact to kill tumor cells

21 January 2018

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Characterization and mechanism of stress-induced translocation of 78-kilodalton glucose-regulated protein (GRP78) to the cell surface

21 January 2018

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Rabbit hemorrhagic viral disease: characterization of a new animal model of fulminant liver failure

21 January 2018

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Melatonin attenuates apoptotic liver damage in fulminant hepatic failure induced by the rabbit hemorrhagic disease virus

21 January 2018

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Molecular chaperone Hsp90 is a therapeutic target for noroviruses

21 January 2018

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OSU-03012 promotes caspase-independent but PERK-, cathepsin B-, BID-, and AIF-dependent killing of transformed cells

21 January 2018

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Heat shock protein 70 is associated with CSFV NS5A protein and enhances viral RNA replication

21 January 2018

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From the cyclooxygenase-2 inhibitor celecoxib to a novel class of 3-phosphoinositide-dependent protein kinase-1 inhibitors

21 January 2018

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N-acetyl-cysteine protects liver from apoptotic death in an animal model of fulminant hepatic failure

21 January 2018

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Activated forms of H-RAS and K-RAS differentially regulate membrane association of PI3K, PDK-1, and AKT and the effect of therapeutic kinase inhibitors on cell survival.

21 January 2018

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12 December 2020

Folding, interaction with GRP78-BiP, assembly, and transport of the human immunodeficiency virus type 1 envelope protein

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12 December 2020

Multi-kinase inhibitors can associate with heat shock proteins through their NH2-termini by which they suppress chaperone function

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12 December 2020

The afatinib resistance of in vivo generated H1975 lung cancer cell clones is mediated by SRC/ERBB3/c-KIT/c-MET compensatory survival signaling

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12 December 2020

[Pemetrexed + Sorafenib] lethality is increased by inhibition of ERBB1/2/3-PI3K-NFκB compensatory survival signaling

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12 December 2020

BiP (GRP78) and endoplasmin (GRP94) are induced following rotavirus infection and bind transiently to an endoplasmic reticulum-localized virion component

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12 December 2020

Identifiers

DOI

10.1002/JCP.25431

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1 April 2020

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