Convergent Signaling Pathways Regulate Parathyroid Hormone and Fibroblast Growth Factor-23 Action on NPT2A-mediated Phosphate Transport (Q38757058)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27432882%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

title

Convergent Signaling Pathways Regulate Parathyroid Hormone and Fibroblast Growth Factor-23 Action on NPT2A-mediated Phosphate Transport (English)

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19 March 2020

3

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19 March 2020

author name string

W Bruce Sneddon

1

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19 March 2020

Giovanni W Ruiz

2

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19 March 2020

Kunhong Xiao

4

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19 March 2020

Qiangmin Zhang

5

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19 March 2020

Youssef Rbaibi

6

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19 March 2020

Ora A Weisz

7

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19 March 2020

Gerard L Apodaca

8

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19 March 2020

Peter A Friedman

9

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19 March 2020

language of work or name

English

0 references

publication date

18 July 2016

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Journal of Biological Chemistry

19 March 2020

published in

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19 March 2020

volume

291

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19 March 2020

issue

36

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19 March 2020

page(s)

18632-18642

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Conditional Deletion of Fgfr1 in the Proximal and Distal Tubule Identifies Distinct Roles in Phosphate and Calcium Transport.

19 March 2020

cites work

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The Fibroblast Growth Factor signaling pathway

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Activation of a non-cAMP/PKA signaling pathway downstream of the PTH/PTHrP receptor is essential for a sustained hypophosphatemic response to PTH infusion in male mice

6 September 2017

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Ezrin-anchored protein kinase A coordinates phosphorylation-dependent disassembly of a NHERF1 ternary complex to regulate hormone-sensitive phosphate transport

6 September 2017

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NHERF-1 and the regulation of renal phosphate reabsoption: a tale of three hormones

6 September 2017

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Structural basis for NHERF1 PDZ domain binding

6 September 2017

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PTH-mediated inhibition of the renal transport of phosphate

6 September 2017

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Fibroblast growth factor-23-mediated inhibition of renal phosphate transport in mice requires sodium-hydrogen exchanger regulatory factor-1 (NHERF-1) and synergizes with parathyroid hormone

6 September 2017

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Dynamic Na+-H+ exchanger regulatory factor-1 association and dissociation regulate parathyroid hormone receptor trafficking at membrane microdomains

6 September 2017

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Phosphate transport in the kidney

6 September 2017

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Acute down-regulation of sodium-dependent phosphate transporter NPT2a involves predominantly the cAMP/PKA pathway as revealed by signaling-selective parathyroid hormone analogs

6 September 2017

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Cooperativity between the phosphorylation of Thr95 and Ser77 of NHERF-1 in the hormonal regulation of renal phosphate transport

6 September 2017

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Klotho: a novel phosphaturic substance acting as an autocrine enzyme in the renal proximal tubule

6 September 2017

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Regulation of phosphate homeostasis by PTH, vitamin D, and FGF23.

6 September 2017

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Isolated C-terminal tail of FGF23 alleviates hypophosphatemia by inhibiting FGF23-FGFR-Klotho complex formation

6 September 2017

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FGF23 decreases renal NaPi-2a and NaPi-2c expression and induces hypophosphatemia in vivo predominantly via FGF receptor 1.

6 September 2017

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NHERF1 mutations and responsiveness of renal parathyroid hormone

6 September 2017

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FGFR3 and FGFR4 do not mediate renal effects of FGF23.

6 September 2017

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6 September 2017

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Klotho converts canonical FGF receptor into a specific receptor for FGF23

6 September 2017

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Defective coupling of apical PTH receptors to phospholipase C prevents internalization of the Na+-phosphate cotransporter NaPi-IIa in Nherf1-deficient mice

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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Targeted disruption of the mouse NHERF-1 gene promotes internalization of proximal tubule sodium-phosphate cotransporter type IIa and renal phosphate wasting

6 September 2017

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Fibroblast growth factor (FGF)-23 inhibits renal phosphate reabsorption by activation of the mitogen-activated protein kinase pathway

6 September 2017

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FGF-23 inhibits renal tubular phosphate transport and is a PHEX substrate

6 September 2017

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6 September 2017

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A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signaling pathway

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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Xeno-Klotho Inhibits Parathyroid Hormone Signaling

6 September 2017

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6 September 2017

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hTERT alone immortalizes epithelial cells of renal proximal tubules without changing their functional characteristics.

14 September 2017

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Heterogeneous ribonucleoprotein m is a splicing regulatory protein that can enhance or silence splicing of alternatively spliced exons

14 September 2017

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Extracellular signal-regulated kinase activation by parathyroid hormone in distal tubule cells

14 September 2017

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Calcium-sensing receptor regulation of PTH-inhibitable proximal tubule phosphate transport

14 September 2017

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Apical and basolateral endocytic pathways of MDCK cells meet in acidic common endosomes distinct from a nearly-neutral apical recycling endosome

14 September 2017

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Selective effects of sodium chlorate treatment on the sulfation of heparan sulfate

25 September 2017

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Regulation of expression of type II sodium-phosphate cotransporters by protein kinases A and C.

25 September 2017

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Unliganded fibroblast growth factor receptor 1 forms density-independent dimers

25 September 2017

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A dual mechanism for regulation of kidney phosphate transport by parathyroid hormone

25 September 2017

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Clonal sublines that are morphologically and functionally distinct from parental OK cells

23 June 2018

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Phosphate transport in established renal epithelial cell lines.

23 June 2018

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FGF23 acts directly on renal proximal tubules to induce phosphaturia through activation of the ERK1/2-SGK1 signaling pathway

23 June 2018

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Immunohistochemical identification of the PTHR1 parathyroid hormone receptor in normal and neoplastic human tissues.

31 August 2018

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Defective PTH regulation of sodium-dependent phosphate transport in NHERF-1-/- renal proximal tubule cells and wild-type cells adapted to low-phosphate media.

31 August 2018

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Kinetic model for FGF, FGFR, and proteoglycan signal transduction complex assembly

31 August 2018

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Localization and interaction of NHERF isoforms in the renal proximal tubule of the mouse.

31 August 2018

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Cell-Specific Expression of the Parathyroid Hormone (PTH)/PTH-Related Peptide Receptor Gene in Kidney from Kidney-Specific and Ubiquitous Promoters

31 August 2018

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Crossref

https://api.crossref.org/works/10.1074%2FJBC.M116.744052

cAMP-dependent and -independent downregulation of type II Na-Pi cotransporters by PTH

21 January 2018

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12 December 2020

Cell-specific expression of the parathyroid hormone (PTH)/PTH-related peptide receptor gene in kidney from kidney-specific and ubiquitous promoters

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12 December 2020

Luminal and contraluminal action of 1-34 and 3-34 PTH peptides on renal type IIa Na-P(i) cotransporter

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12 December 2020

Obligate mitogen-activated protein kinase activation in parathyroid hormone stimulation of calcium transport but not calcium signaling

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12 December 2020

Parathyroid hormone stimulation of calcium transport is mediated by dual signaling mechanisms involving protein kinase A and protein kinase C

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12 December 2020

Identifiers

DOI

10.1074/JBC.M116.744052

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27432882%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27432882%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

1 reference