Stem cells versus plasticity in liver and pancreas regeneration. (Q38748909)

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8 March 2020

title

Stem cells versus plasticity in liver and pancreas regeneration (English)

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8 March 2020

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2

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8 March 2020

author name string

Janel L Kopp

series ordinal

1

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8 March 2020

Maike Sander

series ordinal

3

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8 March 2020

language of work or name

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1 March 2016

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8 March 2020

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8 March 2020

volume

18

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8 March 2020

page(s)

238-245

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8 March 2020

issue

3

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https://scigraph.springernature.com/pub.10.1038/ncb3309

8 March 2020

exact match

0 references

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Continuous cell supply from a Sox9-expressing progenitor zone in adult liver, exocrine pancreas and intestine.

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Adult hepatocytes are generated by self-duplication rather than stem cell differentiation.

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Evidence against a stem cell origin of new hepatocytes in a common mouse model of chronic liver injury

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Bipotential adult liver progenitors are derived from chronically injured mature hepatocytes

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Progressive fibrosis in nonalcoholic steatohepatitis: association with altered regeneration and a ductular reaction.

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Robust cellular reprogramming occurs spontaneously during liver regeneration.

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Hippo pathway activity influences liver cell fate

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Cholangiocarcinomas can originate from hepatocytes in mice

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Intrahepatic cholangiocarcinoma can arise from Notch-mediated conversion of hepatocytes

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Hybrid Periportal Hepatocytes Regenerate the Injured Liver without Giving Rise to Cancer

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Bmi1 lineage tracing identifies a self-renewing pancreatic acinar cell subpopulation capable of maintaining pancreatic organ homeostasis

21 January 2018

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Very slow turnover of beta-cells in aged adult mice

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Conversion of adult pancreatic alpha-cells to beta-cells after extreme beta-cell loss

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Recovery from diabetes in mice by beta cell regeneration

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Long-term recovery of β-cell function after partial pancreatectomy in humans.

21 January 2018

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Partial pancreatectomy in adult humans does not provoke beta-cell regeneration

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Volumetric gain of the human pancreas after left partial pancreatic resection: A CT-scan based retrospective study

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Partial pancreatectomy in the rat and subsequent defect in glucose-induced insulin release

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Discordance of exocrine and endocrine growth after 90% pancreatectomy in rats

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Extra-insular beta cells associated with ductules are frequent in adult human pancreas.

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Pancreatic gastrin stimulates islet differentiation of transforming growth factor alpha-induced ductular precursor cells

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Beta cells can be generated from endogenous progenitors in injured adult mouse pancreas

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Recombinant human betacellulin promotes the neogenesis of beta-cells and ameliorates glucose intolerance in mice with diabetes induced by selective alloxan perfusion

21 January 2018

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Regulation of pancreatic beta-cell regeneration in the normoglycemic 60% partial-pancreatectomy mouse.

21 January 2018

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Direct lineage tracing reveals the ontogeny of pancreatic cell fates during mouse embryogenesis

21 January 2018

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Sox9+ ductal cells are multipotent progenitors throughout development but do not produce new endocrine cells in the normal or injured adult pancreas.

21 January 2018

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Pancreatic exocrine duct cells give rise to insulin-producing beta cells during embryogenesis but not after birth

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Exocrine-to-endocrine differentiation is detectable only prior to birth in the uninjured mouse pancreas.

21 January 2018

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Clonal identification of multipotent precursors from adult mouse pancreas that generate neural and pancreatic lineages

21 January 2018

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The adult mouse and human pancreas contain rare multipotent stem cells that express insulin

21 January 2018

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Multipotential nestin-positive stem cells isolated from adult pancreatic islets differentiate ex vivo into pancreatic endocrine, exocrine, and hepatic phenotypes

21 January 2018

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Prospective isolation of multipotent pancreatic progenitors using flow-cytometric cell sorting.

21 January 2018

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Characterization of endocrine progenitor cells and critical factors for their differentiation in human adult pancreatic cell culture

21 January 2018

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Colony-forming cells in the adult mouse pancreas are expandable in Matrigel and form endocrine/acinar colonies in laminin hydrogel

21 January 2018

1 reference

Unlimited in vitro expansion of adult bi-potent pancreas progenitors through the Lgr5/R-spondin axis

21 January 2018

1 reference

Isolation and characterization of centroacinar/terminal ductal progenitor cells in adult mouse pancreas

21 January 2018

1 reference

Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation

21 January 2018

1 reference

Preexisting pancreatic acinar cells contribute to acinar cell, but not islet beta cell, regeneration.

21 January 2018

1 reference

In vivo lineage tracing defines the role of acinar-to-ductal transdifferentiation in inflammatory ductal metaplasia

21 January 2018

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Activation of pancreatic-duct-derived progenitor cells during pancreas regeneration in adult rats

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Beta-cell growth and regeneration: replication is only part of the story

21 January 2018

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Duct cells contribute to regeneration of endocrine and acinar cells following pancreatic damage in adult mice

21 January 2018

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Neurogenin 3+ cells contribute to β-cell neogenesis and proliferation in injured adult mouse pancreas

21 January 2018

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No evidence for β cell neogenesis in murine adult pancreas

21 January 2018

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Partial duct ligation: β-cell proliferation and beyond.

21 January 2018

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Spatiotemporal patterns of multipotentiality in Ptf1a-expressing cells during pancreas organogenesis and injury-induced facultative restoration

21 January 2018

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Analysis of mPygo2 mutant mice suggests a requirement for mesenchymal Wnt signaling in pancreatic growth and differentiation.

21 January 2018

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Beta-catenin is essential for pancreatic acinar but not islet development

21 January 2018

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Attenuated Wnt signaling perturbs pancreatic growth but not pancreatic function

21 January 2018

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Pancreas-specific deletion of beta-catenin reveals Wnt-dependent and Wnt-independent functions during development.

21 January 2018

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β-Cells are not generated in pancreatic duct ligation-induced injury in adult mice

21 January 2018

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Adult pancreatic acinar cells give rise to ducts but not endocrine cells in response to growth factor signaling

21 January 2018

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Carbonic anhydrase II-positive pancreatic cells are progenitors for both endocrine and exocrine pancreas after birth

21 January 2018

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Lineage tracing reveals the dynamic contribution of Hes1+ cells to the developing and adult pancreas.

21 January 2018

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Progenitor cell domains in the developing and adult pancreas

21 January 2018

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21 January 2018

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21 January 2018

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Impact of Sox9 dosage and Hes1-mediated Notch signaling in controlling the plasticity of adult pancreatic duct cells in mice.

21 January 2018

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Origin of tubular complexes in human chronic pancreatitis

21 January 2018

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Reversible changes in pancreatic islet structure and function produced by elevated blood glucose

21 January 2018

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Pancreatic β cell dedifferentiation as a mechanism of diabetic β cell failure

21 January 2018

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Beta-catenin blocks Kras-dependent reprogramming of acini into pancreatic cancer precursor lesions in mice

21 January 2018

1 reference

Identification of Sox9-dependent acinar-to-ductal reprogramming as the principal mechanism for initiation of pancreatic ductal adenocarcinoma

21 January 2018

1 reference

Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells

21 January 2018

1 reference

Hepatocytes, rather than cholangiocytes, can be the major source of primitive ductules in the chronically injured mouse liver

21 January 2018

1 reference

A clonal marker induced by mutation in mouse intestinal epithelium

21 January 2018

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21 January 2018

1 reference

12 December 2020

Evolution of the clonogenic potential of human epidermal stem/progenitor cells with age.

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12 December 2020

Expansion and conversion of human pancreatic ductal cells into insulin-secreting endocrine cells

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12 December 2020

The stem cells of small intestinal crypts: where are they?

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12 December 2020

1 reference

12 December 2020

The homeodomain protein IDX-1 increases after an early burst of proliferation during pancreatic regeneration

1 reference

12 December 2020

Generation of hepatocytes from oval cell precursors in culture.

1 reference

12 December 2020

The streaming liver II. Hepatocyte life history

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12 December 2020

Fanconi anemia and novel strategies for therapy

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12 December 2020

Time course and cellular source of pancreatic regeneration following acute pancreatitis in the rat.

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12 December 2020

Duct- to islet-cell differentiation and islet growth in the pancreas of duct-ligated adult rats

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12 December 2020

The pancreatic duct cell: proliferative capabilities, specific characteristics, metaplasia, isolation, and culture.

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12 December 2020

Neogenesis and proliferation of beta-cells induced by human betacellulin gene transduction via retrograde pancreatic duct injection of an adenovirus vector

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12 December 2020

Reversal of insulin-dependent diabetes using islets generated in vitro from pancreatic stem cells

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12 December 2020

A precursor-product relationship exists between oval cells and hepatocytes in rat liver

1 reference

12 December 2020

Mitosis and apoptosis in the liver of interleukin-6-deficient mice after partial hepatectomy

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12 December 2020

Immunocytochemical determination of ploidy class-dependent bromodeoxyuridine incorporation in rat liver parenchymal cells after partial hepatectomy

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12 December 2020

Ductular reaction and its diagnostic significance.

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12 December 2020

Recapitulation of elements of embryonic development in adult mouse pancreatic regeneration

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12 December 2020

Analysis of liver development, regeneration, and carcinogenesis by genetic marking studies.

1 reference

12 December 2020

Liver stem cells, where art thou?

1 reference

12 December 2020

Regional differences in the cellular proliferation activity of the regenerating rat pancreas after partial pancreatectomy

1 reference

12 December 2020

In vivo differentiation of rat liver oval cells into hepatocytes.

1 reference

12 December 2020

The canals of Hering and hepatic stem cells in humans

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12 December 2020

Functional activity of murine CD34+ and CD34- hematopoietic stem cell populations

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12 December 2020

Cell lineage study in the liver using retroviral mediated gene transfer. Evidence against the streaming of hepatocytes in normal liver

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12 December 2020

Differentiation and proliferation of endocrine cells in the regenerating rat pancreas after 90% pancreatectomy

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12 December 2020

Differential regeneration of intestinal proliferative cells and cryptogenic cells after irradiation

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12 December 2020

Atypical ductular proliferation and its inhibition by transforming growth factor beta1 in the 3,5-diethoxycarbonyl-1,4-dihydrocollidine mouse model for chronic alcoholic liver disease

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12 December 2020

Identifiers

DOI

10.1038/NCB3309

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26911907%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

8 March 2020

0 references

1 reference

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