Histone variants and melanoma: facts and hypotheses (Q38748010)

6 September 2017

Histone variants and melanoma: facts and hypotheses (English)

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6 September 2017

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Nikifor K Konstantinov

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1

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PubMed ID

26909678

6 September 2017

Constance J Ulff-Møller

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2

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PubMed ID

26909678

6 September 2017

Stefan Dimitrov

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3

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6 September 2017

22 February 2016

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Pigment Cell & Melanoma Research

6 September 2017

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6 September 2017

29

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6 September 2017

4

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6 September 2017

426-433

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Epigenetic determination of a cell-specific gene expression program by ATF-2 and the histone variant macroH2A.

6 September 2017

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

E2F1 in melanoma progression and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

The histone variant macroH2A interferes with transcription factor binding and SWI/SNF nucleosome remodeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

The histone octamer is invisible when NF-kappaB binds to the nucleosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

Topography of the histone octamer surface: repeating structural motifs utilized in the docking of nucleosomal DNA

21 January 2018

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https://api.crossref.org/works/10.1111%2FPCMR.12467

The histone fold: a ubiquitous architectural motif utilized in DNA compaction and protein dimerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

The nucleosomal core histone octamer at 3.1 A resolution: a tripartite protein assembly and a left-handed superhelix

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

Eaf1 is the platform for NuA4 molecular assembly that evolutionarily links chromatin acetylation to ATP-dependent exchange of histone H2A variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

EZH2 expression is associated with high proliferation rate and aggressive tumor subgroups in cutaneous melanoma and cancers of the endometrium, prostate, and breast

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

High-resolution profiling of histone methylations in the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

The folding and unfolding of eukaryotic chromatin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

The molecular pathology of melanoma: an integrated taxonomy of melanocytic neoplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

Transcription factor access to chromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

The chromatin remodelling factor BRG1 is a novel binding partner of the tumor suppressor p16INK4a

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

Distinct H3F3A and H3F3B driver mutations define chondroblastoma and giant cell tumor of bone

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

Reduced H3K27me3 and DNA hypomethylation are major drivers of gene expression in K27M mutant pediatric high-grade gliomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

Histone H3.3. mutations drive pediatric glioblastoma through upregulation of MYCN.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

The replacement histone H2A.Z in a hyperacetylated form is a feature of active genes in the chicken

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

The histone variant macroH2A is an epigenetic regulator of key developmental genes

21 January 2018

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https://api.crossref.org/works/10.1111%2FPCMR.12467

MacroH2A--an epigenetic regulator of cancer

21 January 2018

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https://api.crossref.org/works/10.1111%2FPCMR.12467

Genomic instability in mice lacking histone H2AX

21 January 2018

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https://api.crossref.org/works/10.1111%2FPCMR.12467

H2AX haploinsufficiency modifies genomic stability and tumor susceptibility

21 January 2018

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https://api.crossref.org/works/10.1111%2FPCMR.12467

The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset

21 January 2018

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https://api.crossref.org/works/10.1111%2FPCMR.12467

Histone variant macroH2A contains two distinct macrochromatin domains capable of directing macroH2A to the inactive X chromosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

The histone H3.3K27M mutation in pediatric glioma reprograms H3K27 methylation and gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

macroH2A1-dependent silencing of endogenous murine leukemia viruses

21 January 2018

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https://api.crossref.org/works/10.1111%2FPCMR.12467

MacroH2A1.1 and PARP-1 cooperate to regulate transcription by promoting CBP-mediated H2B acetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

Regions of variant histone His2AvD required for Drosophila development.

21 January 2018

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https://api.crossref.org/works/10.1111%2FPCMR.12467

macroH2A1 histone variant represses rDNA transcription

21 January 2018

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https://api.crossref.org/works/10.1111%2FPCMR.12467

MacroH2A in stem cells: a story beyond gene repression.

21 January 2018

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https://api.crossref.org/works/10.1111%2FPCMR.12467

Ubinuclein-1 confers histone H3.3-specific-binding by the HIRA histone chaperone complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

Solvent mediated interactions in the structure of the nucleosome core particle at 1.9 a resolution

21 January 2018

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https://api.crossref.org/works/10.1111%2FPCMR.12467

Mechanism of polymerase II transcription repression by the histone variant macroH2A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

Dissection of the unusual structural and functional properties of the variant H2A.Bbd nucleosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

The death-associated protein DAXX is a novel histone chaperone involved in the replication-independent deposition of H3.3

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

Characterization of the histone H2A.Z-1 and H2A.Z-2 isoforms in vertebrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

DAXX envelops a histone H3.3-H4 dimer for H3.3-specific recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

Histone variant H2A.Z is required for early mammalian development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

Histone H3 variants and their chaperones during development and disease: contributing to epigenetic control

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

Differential expression of human replacement and cell cycle dependent H3 histone genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

Multiple facets of the unique histone variant macroH2A: from genomics to cell biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

The histone variant macroH2A1 marks repressed autosomal chromatin, but protects a subset of its target genes from silencing

21 January 2018

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https://api.crossref.org/works/10.1111%2FPCMR.12467

Distinct factors control histone variant H3.3 localization at specific genomic regions

21 January 2018

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https://api.crossref.org/works/10.1111%2FPCMR.12467

H2A.Z contributes to the unique 3D structure of the centromere

21 January 2018

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https://api.crossref.org/works/10.1111%2FPCMR.12467

FANCJ localization by mismatch repair is vital to maintain genomic integrity after UV irradiation

21 January 2018

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https://api.crossref.org/works/10.1111%2FPCMR.12467

Assembly of variant histones into chromatin

21 January 2018

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https://api.crossref.org/works/10.1111%2FPCMR.12467

CpG islands--'a rough guide'.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

Chromosome-wide Rad51 spreading and SUMO-H2A.Z-dependent chromosome fixation in response to a persistent DNA double-strand break

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

The histone variant macroH2A suppresses melanoma progression through regulation of CDK8.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

Heterogeneous SWI/SNF chromatin remodeling complexes promote expression of microphthalmia-associated transcription factor target genes in melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

Splicing regulates NAD metabolite binding to histone macroH2A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

Daxx is an H3.3-specific histone chaperone and cooperates with ATRX in replication-independent chromatin assembly at telomeres

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

Structure of the variant histone H3.3–H4 heterodimer in complex with its chaperone DAXX

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

Binding of NF-κB to nucleosomes: effect of translational positioning, nucleosome remodeling and linker histone H1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

Chromatin-remodeling and the initiation of transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

Crystal structure of the nucleosome core particle at 2.8 A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

Neocentromeres: new insights into centromere structure, disease development, and karyotype evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

Expression of polycomb group protein EZH2 in nevi and melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

Histone H2A.Z inheritance during the cell cycle and its impact on promoter organization and dynamics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

QKI-mediated alternative splicing of the histone variant MacroH2A1 regulates cancer cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

ANP32E is a histone chaperone that removes H2A.Z from chromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

The histone variant mH2A1.1 interferes with transcription by down-regulating PARP-1 enzymatic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

MacroH2A, a core histone containing a large nonhistone region

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

Evolutionary conservation of histone macroH2A subtypes and domains

21 January 2018

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https://api.crossref.org/works/10.1111%2FPCMR.12467

RNA interference demonstrates a novel role for H2A.Z in chromosome segregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

ATRX-mediated chromatin association of histone variant macroH2A1 regulates α-globin expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

PARP-1 regulates metastatic melanoma through modulation of vimentin-induced malignant transformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

Monoubiquitylation of H2A.Z distinguishes its association with euchromatin or facultative heterochromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

Remosomes: RSC generated non-mobilized particles with approximately 180 bp DNA loosely associated with the histone octamer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

Epigenetics of human cutaneous melanoma: setting the stage for new therapeutic strategies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

Histone variants in pluripotency and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

A unique H2A histone variant occupies the transcriptional start site of active genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

Cryo-EM study of the chromatin fiber reveals a double helix twisted by tetranucleosomal units

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

Differential regulation and predictive potential of MacroH2A1 isoforms in colon cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

Laser-induced crosslinking of histones to DNA in chromatin and core particles: implications in studying histone-DNA interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

The language of covalent histone modifications

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

Crystal structure of a nucleosome core particle containing the variant histone H2A.Z

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

Single-base resolution mapping of H1-nucleosome interactions and 3D organization of the nucleosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

Histone H3.1 and H3.3 complexes mediate nucleosome assembly pathways dependent or independent of DNA synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

Histone variants--ancient wrap artists of the epigenome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

Involvement of histone H1 in the organization of the nucleosome and of the salt-dependent superstructures of chromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

Genomic Classification of Cutaneous Melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

Histone variants: emerging players in cancer biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

Histone Variant H2A.Z.2 Mediates Proliferation and Drug Sensitivity of Malignant Melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

Epigenetic activation of a cryptic TBC1D16 transcript enhances melanoma progression by targeting EGFR

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

Unusual structure, evolutionary conservation of non-coding sequences and numerous pseudogenes characterize the human H3.3 histone multigene family

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

Active DNA demethylation: many roads lead to Rome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

The epigenetic modifier EZH2 controls melanoma growth and metastasis through silencing of distinct tumour suppressors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

Histone macroH2A isoforms predict the risk of lung cancer recurrence

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12467

21 January 2018

Identifiers

DOI

10.1111/PCMR.12467

1 reference

6 September 2017

1 reference

PubMed ID

26909678