Suppression of Type I IFN Signaling in Tumors Mediates Resistance to Anti-PD-1 Treatment That Can Be Overcome by Radiotherapy (Q38732479)

28 June 2018

title

Suppression of Type I IFN Signaling in Tumors Mediates Resistance to Anti-PD-1 Treatment That Can Be Overcome by Radiotherapy (English)

1 reference

28 June 2018

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12

James P Allison

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Ritsuko Komaki

15

object named as

Ritsuko Komaki

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28 June 2018

19

Stephen M Hahn

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28 June 2018

Patrick Hwu

14

object named as

Patrick Hwu

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28 June 2018

author name string

Xiaohong Wang

1

1 reference

28 June 2018

Jonathan E Schoenhals

2

1 reference

28 June 2018

Ailin Li

3

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28 June 2018

David R Valdecanas

4

1 reference

28 June 2018

Huiping Ye

5

1 reference

28 June 2018

Fenglin Zang

6

1 reference

28 June 2018

Chad Tang

7

1 reference

28 June 2018

Ming Tang

8

1 reference

28 June 2018

Chang-Gong Liu

9

1 reference

28 June 2018

Xiuping Liu

10

1 reference

28 June 2018

Sunil Krishnan

11

1 reference

28 June 2018

Padmanee Sharma

13

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28 June 2018

Willem W Overwijk

16

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28 June 2018

Daniel R Gomez

17

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28 June 2018

Joe Y Chang

18

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28 June 2018

Maria Angelica Cortez

20

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28 June 2018

James W Welsh

21

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28 June 2018

language of work or name

English

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publication date

7 November 2016

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28 June 2018

published in

Cancer Research

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28 June 2018

volume

77

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28 June 2018

issue

4

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28 June 2018

page(s)

839-850

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28 June 2018

Mutations Associated with Acquired Resistance to PD-1 Blockade in Melanoma

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Reflections on the Histopathology of Tumor-Infiltrating Lymphocytes in Melanoma and the Host Immune Response

30 June 2018

1 reference

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A Threshold Level of Intratumor CD8+ T-cell PD1 Expression Dictates Therapeutic Response to Anti-PD1.

30 June 2018

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Tumor infiltrating CD8(+) T lymphocyte count is independent of tumor TLR9 status in treatment naïve triple negative breast cancer and renal cell carcinoma

30 June 2018

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Stereotactic ablative radiotherapy versus lobectomy for operable stage I non-small-cell lung cancer: a pooled analysis of two randomised trials

30 June 2018

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Cancer immunology. Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer

30 June 2018

1 reference

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Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer

30 June 2018

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β2-Microglobulin deficiency causes a complex immunodeficiency of the innate and adaptive immune system.

30 June 2018

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STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors.

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5875182

PD-1 blockade induces responses by inhibiting adaptive immune resistance

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5875182

Genetic evolution of T-cell resistance in the course of melanoma progression

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5875182

B7-H1/PD-1 blockade therapy in non-small cell lung cancer: current status and future direction

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5875182

ZEB1 sensitizes lung adenocarcinoma to metastasis suppression by PI3K antagonism

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5875182

Irradiation and anti-PD-L1 treatment synergistically promote antitumor immunity in mice.

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5875182

Type I interferons induced by radiation therapy mediate recruitment and effector function of CD8(+) T cells

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5875182

Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5875182

Safety, activity, and immune correlates of anti-PD-1 antibody in cancer

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5875182

Targeting the PD-1/B7-H1(PD-L1) pathway to activate anti-tumor immunity

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5875182

The efficacy of radiotherapy relies upon induction of type i interferon-dependent innate and adaptive immunity

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5875182

Prognostic significance of grading in lung adenocarcinoma

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5875182

Contextual extracellular cues promote tumor cell EMT and metastasis by regulating miR-200 family expression

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5875182

Therapeutic effects of ablative radiation on local tumor require CD8+ T cells: changing strategies for cancer treatment

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5875182

Somatic mutations affect key pathways in lung adenocarcinoma

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5875182

MHC class I antigens and immune surveillance in transformed cells.

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5875182

Radiation modulates the peptide repertoire, enhances MHC class I expression, and induces successful antitumor immunotherapy

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5875182

Tumour necrosis is an independent prognostic marker in non-small cell lung cancer: correlation with biological variables

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5875182

Induction of cell death by radiotherapy

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5875182

Loss of functional beta 2-microglobulin in metastatic melanomas from five patients receiving immunotherapy

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5875182

Lack of HLA class I antigen expression by cultured melanoma cells FO-1 due to a defect in B2m gene expression

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5875182

A Grading System of Lung Adenocarcinomas Based on Histologic Pattern is Predictive of Disease Recurrence in Stage I Tumors

30 June 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27821490

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1158/0008-5472.CAN-15-3142

1 reference

28 June 2018

PMCID

5875182

1 reference

28 June 2018

PubMed ID

27821490

1 reference

28 June 2018