Novel molecular mechanisms and regeneration therapy for heart failure (Q38717572)

5 September 2017

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title

Novel molecular mechanisms and regeneration therapy for heart failure (English)

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5 September 2017

3

Issei Komuro

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5 September 2017

Toru Oka

1

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PubMed ID

26829118

5 September 2017

Hiroyuki Morita

series ordinal

2

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5 September 2017

29 January 2016

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Journal of Molecular and Cellular Cardiology

5 September 2017

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5 September 2017

92

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5 September 2017

46-51

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Re-employment of developmental transcription factors in adult heart disease

5 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

CaMKII in myocardial hypertrophy and heart failure

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

Mechanisms of non-apoptotic programmed cell death in diabetes and heart failure

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

ECM remodeling in hypertensive heart disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

Myocardial matrix remodeling and the matrix metalloproteinases: influence on cardiac form and function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

Pathophysiology of myocardial reperfusion injury: preconditioning, postconditioning, and translational aspects of protective measures

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

Mitochondrial adaptations to physiological vs. pathological cardiac hypertrophy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

Proliferative signaling and disease progression in heart failure

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

Multiple facets of NF-κB in the heart: to be or not to NF-κB.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

Targeting the TGFbeta, endothelin-1 and CCN2 axis to combat fibrosis in scleroderma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

Epigenetics and cardiovascular development.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

Estimating myocardial damage and the need for surgery in patients with valvular heart disease by Tl-201 SPECT

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

Angiogenesis in skeletal and cardiac muscle.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

Disruption of coordinated cardiac hypertrophy and angiogenesis contributes to the transition to heart failure

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

Vascular endothelial growth factor blockade promotes the transition from compensatory cardiac hypertrophy to failure in response to pressure overload

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

Cardiomyocyte GATA4 functions as a stress-responsive regulator of angiogenesis in the murine heart

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

The zinc finger-containing transcription factors GATA-4, -5, and -6. Ubiquitously expressed regulators of tissue-specific gene expression.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

Cardiac-Specific Deletion of Gata4 Reveals Its Requirement for Hypertrophy, Compensation, and Myocyte Viability

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

Cardiac growth and angiogenesis coordinated by intertissue interactions

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

p53-induced inhibition of Hif-1 causes cardiac dysfunction during pressure overload

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

Transition from compensated hypertrophy to intrinsic myocardial dysfunction during development of left ventricular pressure-overload hypertrophy in conscious sheep. Systolic dysfunction precedes diastolic dysfunction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

Chronic doxorubicin cardiotoxicity is mediated by oxidative DNA damage-ATM-p53-apoptosis pathway and attenuated by pitavastatin through the inhibition of Rac1 activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

Promotion of CHIP-mediated p53 degradation protects the heart from ischemic injury

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

Ca2+/calmodulin-dependent kinase IIdelta causes heart failure by accumulation of p53 in dilated cardiomyopathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

Stabilization of wild-type p53 by hypoxia-inducible factor 1alpha

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

Critical roles of muscle-secreted angiogenic factors in therapeutic neovascularization.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

Long-term outcome of therapeutic neovascularization using peripheral blood mononuclear cells for limb ischemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

Magnetic resonance mapping demonstrates benefits of VEGF-induced myocardial angiogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

Gene therapy for myocardial angiogenesis: initial clinical results with direct myocardial injection of phVEGF165 as sole therapy for myocardial ischemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

Therapeutic angiogenesis in chronically ischemic porcine myocardium: comparative effects of bFGF and VEGF.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

VEGF165 and angiopoietin-1 decreased myocardium infarct size through phosphatidylinositol-3 kinase and Bcl-2 pathways.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

Intramyocardial VEGF-B167 gene delivery delays the progression towards congestive failure in dogs with pacing-induced dilated cardiomyopathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

Vascular endothelial growth factor-B gene transfer prevents angiotensin II-induced diastolic dysfunction via proliferation and capillary dilatation in rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

AAV9-mediated VEGF-B gene transfer improves systolic function in progressive left ventricular hypertrophy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

Intracoronary injection of basic fibroblast growth factor enhances angiogenesis in infarcted swine myocardium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

Intracoronary basic fibroblast growth factor (FGF-2) in patients with severe ischemic heart disease: results of a phase I open-label dose escalation study.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

Intracoronary gene transfer of fibroblast growth factor-5 increases blood flow and contractile function in an ischemic region of the heart

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

Adenoviral gene transfer of FGF-5 to hibernating myocardium improves function and stimulates myocytes to hypertrophy and reenter the cell cycle

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

Plasmid-based transient human stromal cell-derived factor-1 gene transfer improves cardiac function in chronic heart failure

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

Stromal cell-derived factor-1 retention and cardioprotection for ischemic myocardium.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

hHGF overexpression in myoblast sheets enhances their angiogenic potential in rat chronic heart failure

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

Midkine gene transfer after myocardial infarction in rats prevents remodelling and ameliorates cardiac dysfunction.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

Pathophysiological consequences of VEGF-induced vascular permeability

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

Additive effect of AAV-mediated angiopoietin-1 and VEGF expression on the therapy of infarcted heart

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

Coexpression of VEGF and angiopoietin-1 promotes angiogenesis and cardiomyocyte proliferation reduces apoptosis in porcine myocardial infarction (MI) heart

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

Hypoxia-inducible factors in physiology and medicine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

Improved cardiac contractile functions in hypoxia-reoxygenation in rats treated with low concentration Co(2+)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

Copper regulation of hypoxia-inducible factor-1 activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

Copper is required for cobalt-induced transcriptional activity of hypoxia-inducible factor-1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

Dietary copper supplementation reverses hypertrophic cardiomyopathy induced by chronic pressure overload in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

7 January 2021

Regenerating the heart

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https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

Cardiac progenitor cells from adult myocardium: Homing, differentiation, and fusion after infarction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

Adult cardiac Sca-1-positive cells differentiate into beating cardiomyocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

Adult cardiac stem cells are multipotent and support myocardial regeneration

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

Cardiac neural crest cells contribute to the dormant multipotent stem cell in the mammalian heart

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

Cardiac side population cells have a potential to migrate and differentiate into cardiomyocytes in vitro and in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

Isl1 identifies a cardiac progenitor population that proliferates prior to differentiation and contributes a majority of cells to the heart

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

Postnatal isl1+ cardioblasts enter fully differentiated cardiomyocyte lineages

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

Bone morphogenetic proteins induce cardiomyocyte differentiation through the mitogen-activated protein kinase kinase kinase TAK1 and cardiac transcription factors Csx/Nkx-2.5 and GATA-4

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

IGFBP-4 is an inhibitor of canonical Wnt signalling required for cardiogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

A stromal cell-derived membrane protein that supports hematopoietic stem cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

Initiation of mammalian liver development from endoderm by fibroblast growth factors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

Insulin-like growth factor binding protein-4 differentially inhibits growth factor-induced angiogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2016.01.028

10.1016/J.YJMCC.2016.01.028

7 January 2021

Identifiers

DOI

1 reference

5 September 2017

1 reference

PubMed ID

26829118