Chemical synthesis of site-specifically 2'-azido-modified RNA and potential applications for bioconjugation and RNA interference (Q38712866)

5 September 2017

Chemical synthesis of site-specifically 2'-azido-modified RNA and potential applications for bioconjugation and RNA interference (English)

1 reference

5 September 2017

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5

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5 September 2017

Michaela Aigner

1

1 reference

5 September 2017

Markus Hartl

2

1 reference

5 September 2017

Katja Fauster

3

1 reference

5 September 2017

Jessica Steger

4

1 reference

5 September 2017

Ronald Micura

6

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5 September 2017

1 January 2011

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5 September 2017

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5 September 2017

12

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5 September 2017

1

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5 September 2017

47-51

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New strategy for the synthesis of chemically modified RNA constructs exemplified by hairpin and hammerhead ribozymes

5 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3193913

Structural and functional insights into 5′-ppp RNA pattern recognition by the innate immune receptor RIG-I

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3193913

Chemical modification of siRNA.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3193913

Click chemistry with DNA.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3193913

Stem cell-specific activation of an ancestral myc protooncogene with conserved basic functions in the early metazoan Hydra

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3193913

Chemical RNA modifications for studies of RNA structure and dynamics.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3193913

Exploring chemical modifications for siRNA therapeutics: a structural and functional outlook

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3193913

Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3193913

Causes and consequences of microRNA dysregulation in cancer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3193913

Azide solid support for 3'-conjugation of oligonucleotides and their circularization by click chemistry

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3193913

siRNAs: their potential as therapeutic agents--Part II. Methods of delivery

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3193913

Inhibition of Myc-induced cell transformation by brain acid-soluble protein 1 (BASP1).

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3193913

A large-scale chemical modification screen identifies design rules to generate siRNAs with high activity, high stability and low toxicity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3193913

Structure of an argonaute silencing complex with a seed-containing guide DNA and target RNA duplex

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3193913

Chemical modification of siRNAs for in vivo use.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3193913

Structure of the guide-strand-containing argonaute silencing complex

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3193913

Chemically modified siRNA: tools and applications.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3193913

Solid-phase synthesis of siRNA oligonucleotides.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3193913

Crystal structure, stability and in vitro RNAi activity of oligoribonucleotides containing the ribo-difluorotoluyl nucleotide: insights into substrate requirements by the human RISC Ago2 enzyme

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3193913

Synthesis of coumarin or ferrocene labeled nucleosides via Staudinger ligation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3193913

Quenched probes for highly specific detection of cellular RNAs

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3193913

Visualizing the distribution and transport of mRNAs in living cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3193913

Site-specific fluorescent labeling of DNA using Staudinger ligation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3193913

Incorporation of azides into recombinant proteins for chemoselective modification by the Staudinger ligation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3193913

Molecular beacons: probes that fluoresce upon hybridization

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3193913

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3193913

The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3193913

Interferon Induction by a 2'-Modified Double-Helical RNA, Poly(2'-azido-2'-deoxyinosinic acid) . polycytidylic acid

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3193913

A screen of chemical modifications identifies position-specific modification by UNA to most potently reduce siRNA off-target effects

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3193913

A Y639F/H784A T7 RNA polymerase double mutant displays superior properties for synthesizing RNAs with non-canonical NTPs

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3193913

Positional effect of chemical modifications on short interference RNA activity in mammalian cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3193913

Nucleic acid-incorporated azidonucleotides: probes for studying the interaction of RNA or DNA with proteins and other nucleic acids

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3193913

2'-Methylseleno-modified oligoribonucleotides for X-ray crystallography synthesized by the ACE RNA solid-phase approach

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3193913

Synthesis and characterization of potential interferon inducers. Poly(2'-azido-2'-deoxyuridylic acid).

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3193913

Synthesis of RNA by the rapid phosphotriester method using azido-based 2'-O-protecting groups

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3193913

Synthesis and polymerase chain reaction amplification of DNA strands containing an unnatural triazole linkage

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3193913

Utilization of intrachain 4'-C-azidomethylthymidine for preparation of oligodeoxyribonucleotide conjugates by click chemistry in solution and on a solid support

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3193913

Synthesis of functionalised nucleosides for incorporation into nucleic acid-based serine protease mimics.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3193913

RNA interference tolerates 2'-fluoro modifications at the Argonaute2 cleavage site.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3193913

Syntheses of RNAs with up to 100 nucleotides containing site-specific 2'-methylseleno labels for use in X-ray crystallography.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3193913

Fully 2'-modified oligonucleotide duplexes with improved in vitro potency and stability compared to unmodified small interfering RNA.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3193913

Stereodefined synthesis of O3'-labeled uracil nucleosides. 3'-[(17)O]-2'-Azido-2'-deoxyuridine 5'-diphosphate as a probe for the mechanism of inactivation of ribonucleotide reductases

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3193913

RNA interference: from basic research to therapeutic applications

31 August 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201000646

Monomers for oligonucleotide synthesis with linkers carrying reactive residues: II. Synthesis of phosphoamidites based of uridine and cytosine and containing a linker with methoxyoxalamide groups in position 2'

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201000646

Bioorthogonal chemistry: fishing for selectivity in a sea of functionality

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201000646

Postsynthetic DNA modification through the copper-catalyzed azide-alkyne cycloaddition reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201000646

Efficient access to nonhydrolyzable initiator tRNA based on the synthesis of 3'-azido-3'-deoxyadenosine RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201000646

Small interfering RNAs and their chemical synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201000646

Triplex molecular beacons as modular probes for DNA detection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201000646

A highly sensitive, excimer-controlled molecular beacon.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201000646

2'-Amino-2'-deoxyuridine via an Intramolecular Cyclization of a Trichloroacetimidate

21 January 2018

1 reference

12 December 2020

Polynucleotides containing 2'-amino-2'-deoxyribose and 2'-azido-2'-deoxyribose

1 reference

12 December 2020

Conversion of Aryl Azides to O-Alkyl Imidates via Modified Staudinger Ligation

1 reference

12 December 2020

Chemical synthesis of selenium-modified oligoribonucleotides and their enzymatic ligation leading to an U6 SnRNA stem-loop segment

1 reference

12 December 2020

Identifiers

DOI

10.1002/CBIC.201000646

1 reference

5 September 2017

1 reference

5 September 2017

1 reference