Endothelial to mesenchymal transition (EndoMT) in the pathogenesis of Systemic Sclerosis-associated pulmonary fibrosis and pulmonary arterial hypertension. Myth or reality? (Q38710580)

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English	Endothelial to mesenchymal transition (EndoMT) in the pathogenesis of Systemic Sclerosis-associated pulmonary fibrosis and pulmonary arterial hypertension. Myth or reality?	scientific article

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scholarly article

1 reference

Europe PubMed Central

5 September 2017

Endothelial to mesenchymal transition (EndoMT) in the pathogenesis of Systemic Sclerosis-associated pulmonary fibrosis and pulmonary arterial hypertension. Myth or reality? (English)

1 reference

Europe PubMed Central

5 September 2017

0 references

0 references

arterial hypertension

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pulmonary fibrosis

1 reference

based on heuristic

inferred from title

author name string

Sergio A Jimenez

1

1 reference

Europe PubMed Central

5 September 2017

Sonsoles Piera-Velazquez

2

1 reference

Europe PubMed Central

5 September 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

22 January 2016

1 reference

Europe PubMed Central

5 September 2017

1 reference

Europe PubMed Central

5 September 2017

51

1 reference

Europe PubMed Central

5 September 2017

26-36

1 reference

Europe PubMed Central

5 September 2017

Endothelial Cells Expressing Endothelial and Mesenchymal Cell Gene Products in Lung Tissue From Patients With Systemic Sclerosis-Associated Interstitial Lung Disease

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6 September 2017

Cardiac fibroblasts: from development to heart failure.

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6 September 2017

Pathogenesis of Systemic Sclerosis

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6 September 2017

To be EndMT or not to be, that is the question in pulmonary hypertension

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6 September 2017

Snail Is a Direct Target of Hypoxia-inducible Factor 1α (HIF1α) in Hypoxia-induced Endothelial to Mesenchymal Transition of Human Coronary Endothelial Cells.

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6 September 2017

The extracellular matrix and transforming growth factor-β1: Tale of a strained relationship

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6 September 2017

Diverse origins of the myofibroblast—implications for kidney fibrosis

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6 September 2017

Perivascular Gli1+ progenitors are key contributors to injury-induced organ fibrosis.

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6 September 2017

Transforming growth factor β--at the centre of systemic sclerosis

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Resident fibroblast lineages mediate pressure overload-induced cardiac fibrosis

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Fibroblasts in fibrosis: novel roles and mediators

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6 September 2017

Review: interstitial lung disease associated with systemic sclerosis and idiopathic pulmonary fibrosis: how similar and distinct?

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TGF-β signaling mediates endothelial-to-mesenchymal transition (EndMT) during vein graft remodeling

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6 September 2017

Molecular mechanisms of epithelial-mesenchymal transition

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6 September 2017

Role of endothelial to mesenchymal transition in the pathogenesis of the vascular alterations in systemic sclerosis

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6 September 2017

Origin and function of myofibroblasts in kidney fibrosis

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6 September 2017

Scleroderma pathogenesis: a pivotal role for fibroblasts as effector cells

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Review: evidence that systemic sclerosis is a vascular disease

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Role of caveolin-1 in fibrotic diseases

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6 September 2017

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6 September 2017

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6 September 2017

Morphogen pathways as molecular targets for the treatment of fibrosis in systemic sclerosis

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6 September 2017

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6 September 2017

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6 September 2017

The role of endothelial-mesenchymal transition in development and pathological process

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6 September 2017

Wnt/β-catenin signaling and disease

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6 September 2017

Hypoxia and hypoxia signaling in tissue repair and fibrosis.

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6 September 2017

Recent developments in myofibroblast biology: paradigms for connective tissue remodeling

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6 September 2017

Notch and disease: a growing field

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6 September 2017

β-catenin is a central mediator of pro-fibrotic Wnt signaling in systemic sclerosis

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6 September 2017

Wnt/β-catenin signaling is hyperactivated in systemic sclerosis and induces Smad-dependent fibrotic responses in mesenchymal cells

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6 September 2017

Notch signaling in human development and disease

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6 September 2017

Hypoxia-inducible factors in physiology and medicine

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6 September 2017

Sonic hedgehog signaling mediates epithelial-mesenchymal communication and promotes renal fibrosis

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6 September 2017

Aberrant Hedgehog ligands induce progressive pancreatic fibrosis by paracrine activation of myofibroblasts and ductular cells in transgenic zebrafish

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6 September 2017

Inflammation-induced endothelial-to-mesenchymal transition: a novel mechanism of intestinal fibrosis

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6 September 2017

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6 September 2017

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6 September 2017

Role of endothelial-mesenchymal transition (EndoMT) in the pathogenesis of fibrotic disorders

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6 September 2017

Recent advances in the diagnosis and treatment of interstitial lung disease in systemic sclerosis (scleroderma): a review.

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6 September 2017

Transforming growth factor-β2 promotes Snail-mediated endothelial-mesenchymal transition through convergence of Smad-dependent and Smad-independent signalling.

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6 September 2017

Nuclear β-catenin is increased in systemic sclerosis pulmonary fibrosis and promotes lung fibroblast migration and proliferation

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6 September 2017

Protein kinase Cδ and c-Abl kinase are required for transforming growth factor β induction of endothelial-mesenchymal transition in vitro

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6 September 2017

The role of endothelin-1 signaling in the fibrosis observed in systemic sclerosis

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6 September 2017

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6 September 2017

Hypoxia-inducible factor-1α regulates the expression of genes in hypoxic hepatic stellate cells important for collagen deposition and angiogenesis

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6 September 2017

Review: Endothelial-myofibroblast transition, a new player in diabetic renal fibrosis.

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

Fibroblasts in kidney fibrosis emerge via endothelial-to-mesenchymal transition

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6 September 2017

Slug is a direct Notch target required for initiation of cardiac cushion cellularization

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6 September 2017

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6 September 2017

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6 September 2017

Hypoxia promotes fibrogenesis in vivo via HIF-1 stimulation of epithelial-to-mesenchymal transition

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6 September 2017

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6 September 2017

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6 September 2017

Endothelial-to-mesenchymal transition contributes to cardiac fibrosis

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

Caveolin-1: a critical regulator of lung fibrosis in idiopathic pulmonary fibrosis

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6 September 2017

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6 September 2017

Cellular origins of fibroblasts: possible implications for organ fibrosis in systemic sclerosis

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6 September 2017

Notch activation results in phenotypic and functional changes consistent with endothelial-to-mesenchymal transformation

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6 September 2017

Following the molecular pathways toward an understanding of the pathogenesis of systemic sclerosis

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6 September 2017

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6 September 2017

C3a and C5a receptor antagonists ameliorate endothelial-myofibroblast transition via the Wnt/β-catenin signaling pathway in diabetic kidney disease

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6 September 2017

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6 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

Hypoxia-inducible factor-1alpha induces Twist expression in tubular epithelial cells subjected to hypoxia, leading to epithelial-to-mesenchymal transition

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14 September 2017

The myofibroblast: a key cell for wound healing and fibrocontractive diseases

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14 September 2017

Synergistic cooperation between hypoxia and transforming growth factor-beta pathways on human vascular endothelial growth factor gene expression

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25 September 2017

Myofibroblasts from scleroderma skin synthesize elevated levels of collagen and tissue inhibitor of metalloproteinase (TIMP-1) with two forms of TIMP-1.

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25 September 2017

Identification of Endothelial-to-Mesenchymal Transition as a Potential Participant in Radiation Proctitis

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23 June 2018

Developmental heterogeneity of cardiac fibroblasts does not predict pathological proliferation and activation

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23 June 2018

Molecular mechanisms of endothelial to mesenchymal cell transition (EndoMT) in experimentally induced fibrotic diseases

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23 June 2018

Caveolin-1 deficiency induces spontaneous endothelial-to-mesenchymal transition in murine pulmonary endothelial cells in vitro

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23 June 2018

Connective tissue disease: SSc-fibrosis takes flight with Wingless inhibition.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842122

23 June 2018

Caveolin-1 modulates TGF-β1 signaling in cardiac remodeling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842122

23 June 2018

Experimental myocardial infarction triggers canonical Wnt signaling and endothelial-to-mesenchymal transition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842122

23 June 2018

Decreased expression of caveolin 1 in patients with systemic sclerosis: crucial role in the pathogenesis of tissue fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842122

23 June 2018

The Endothelial-mesenchymal Transition in Systemic Sclerosis Is Induced by Endothelin-1 and Transforming Growth Factor-β and May Be Blocked by Macitentan, a Dual Endothelin-1 Receptor Antagonist.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842122

31 August 2018

Endothelial to Mesenchymal Transition Contributes to Endothelial Dysfunction in Pulmonary Arterial Hypertension.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842122

31 August 2018

A Hypoxia-Induced Vascular Endothelial-to-Mesenchymal Transition in Development of Radiation-Induced Pulmonary Fibrosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842122

31 August 2018

Endothelial-to-mesenchymal transition in pulmonary hypertension.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842122

31 August 2018

Combined inhibition of morphogen pathways demonstrates additive antifibrotic effects and improved tolerability.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842122

31 August 2018

The Wnt antagonists DKK1 and SFRP1 are downregulated by promoter hypermethylation in systemic sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842122

31 August 2018

Dkk1 and MSX2-Wnt7b signaling reciprocally regulate the endothelial-mesenchymal transition in aortic endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842122

31 August 2018

Role of Sonic Hedgehog in idiopathic pulmonary fibrosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842122

31 August 2018

Hedgehog signaling controls fibroblast activation and tissue fibrosis in systemic sclerosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842122

31 August 2018

Notch initiates the endothelial-to-mesenchymal transition in the atrioventricular canal through autocrine activation of soluble guanylyl cyclase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842122

31 August 2018

Endothelial cell-derived endothelin-1 promotes cardiac fibrosis in diabetic hearts through stimulation of endothelial-to-mesenchymal transition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842122

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842122

31 August 2018

Short-Term Administration of a Cell-Permeable Caveolin-1 Peptide Prevents the Development of Monocrotaline-Induced Pulmonary Hypertension and Right Ventricular Hypertrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842122

3 December 2018

Antifibrotic properties of caveolin-1 scaffolding domain in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/26807760

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fibrocytes in health and disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/26807760

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Connective tissue disease-associated pulmonary arterial hypertension

1 reference

https://pubmed.ncbi.nlm.nih.gov/26807760

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endothelial-mesenchymal transition occurs during embryonic pulmonary artery development

1 reference

https://pubmed.ncbi.nlm.nih.gov/26807760

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endothelins: effect on matrix biosynthesis and proliferation in normal and scleroderma fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/26807760

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of growth factors in the pathogenesis of tissue fibrosis in systemic sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/26807760

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Myofibroblast induction and microvascular alteration in scleroderma lung fibrosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/26807760

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Pathogenesis of Systemic Sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/26807760

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interstitial lung disease in systemic sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/26807760

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.MATBIO.2016.01.012

1 reference

Europe PubMed Central

5 September 2017

1 reference

Europe PubMed Central

5 September 2017

1 reference

Europe PubMed Central

5 September 2017

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