The glycocalyx and its significance in human medicine (Q38691530)

5 September 2017

The glycocalyx and its significance in human medicine (English)

1 reference

5 September 2017

0 references

J M Tarbell

1

1 reference

PubMed ID

26749537

5 September 2017

L M Cancel

series ordinal

2

1 reference

PubMed ID

26749537

5 September 2017

language of work or name

English

0 references

publication date

8 January 2016

1 reference

Journal of Internal Medicine

5 September 2017

1 reference

5 September 2017

280

1 reference

5 September 2017

1

1 reference

5 September 2017

97-113

1 reference

Degradation of the endothelial glycocalyx in clinical settings: searching for the sheddases

5 September 2017

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Mechano-sensing and transduction by endothelial surface glycocalyx: composition, structure, and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Fluid Mechanics, Arterial Disease, and Gene Expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Mechanosensing at the vascular interface

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Mechanotransduction and the glycocalyx

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Imaging the endothelial glycocalyx in vitro by rapid freezing/freeze substitution transmission electron microscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Role of the glycocalyx in regulating access of microparticles to apical plasma membranes of intestinal epithelial cells: implications for microbial attachment and oral vaccine targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Molecular organization of the mucins and glycocalyx underlying mucus transport over mucosal surfaces of the airways

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Vascular smooth muscle cell glycocalyx influences shear stress-mediated contractile response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

A potential gravity-sensing role of vascular smooth muscle cell glycocalyx in altered gravitational stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Cancer cell glycocalyx mediates mechanotransduction and flow-regulated invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

The use of HA oligosaccharide-loaded nanoparticles to breach the endogenous hyaluronan glycocalyx for breast cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

An Integrative Review of Mechanotransduction in Endothelial, Epithelial (Renal) and Dendritic Cells (Osteocytes).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Dendritic processes of osteocytes are mechanotransducers that induce the opening of hemichannels

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

The glycocalyx is present as soon as blood flow is initiated and is required for normal vascular development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Proteoglycans in stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Heparan sulfate proteoglycan mediates shear stress-induced endothelial gene expression in mouse embryonic stem cell-derived endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

The structural stability of the endothelial glycocalyx after enzymatic removal of glycosaminoglycans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Sphingosine-1-phosphate protects endothelial glycocalyx by inhibiting syndecan-1 shedding

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Endothelial glycocalyx shedding and vascular permeability in severely injured trauma patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Heparan Sulfate Regrowth Profiles Under Laminar Shear Flow Following Enzymatic Degradation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Hemodynamic shear stress characteristic of atherosclerosis-resistant regions promotes glycocalyx formation in cultured endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Atherogenic region and diet diminish glycocalyx dimension and increase intima-to-media ratios at murine carotid artery bifurcation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Impaired glycocalyx barrier properties contribute to enhanced intimal low-density lipoprotein accumulation at the carotid artery bifurcation in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Inhibition of hyaluronan synthesis accelerates murine atherosclerosis: novel insights into the role of hyaluronan synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

The atypical mechanosensitive microRNA-712 derived from pre-ribosomal RNA induces endothelial inflammation and atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Control of the arteriolar myogenic response by transvascular fluid filtration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Heparan sulfate proteoglycans mediate interstitial flow mechanotransduction regulating MMP-13 expression and cell motility via FAK-ERK in 3D collagen

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Fluid flow mechanotransduction in vascular smooth muscle cells and fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Blood-brain barrier disruption in the hypothalamus of young adult spontaneously hypertensive rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Blood-brain barrier is impaired in the hippocampus of young adult spontaneously hypertensive rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Sublingual microvascular glycocalyx dimensions in lacunar stroke patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Excessive erythrocytosis compromises the blood-endothelium interface in erythropoietin-overexpressing mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Effects of S-nitrosoglutathione on acute vasoconstriction and glutamate release after subarachnoid hemorrhage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Sympathoadrenal activation and endothelial damage in patients with varying degrees of acute infectious disease: an observational study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Vascular adhesion protein-1 and syndecan-1 in septic shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Alteration of the sublingual microvascular glycocalyx in critically ill patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Syndecan-1 shedding facilitates the resolution of neutrophilic inflammation by removing sequestered CXC chemokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

The pulmonary endothelial glycocalyx regulates neutrophil adhesion and lung injury during experimental sepsis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Messengers without borders: mediators of systemic inflammatory response in AKI.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

High glucose attenuates shear-induced changes in endothelial hydraulic conductivity by degrading the glycocalyx

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

High glucose-mediated loss of cell surface heparan sulfate proteoglycan impairs the endothelial shear stress response

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Endothelial function in individuals with coronary artery disease with and without type 2 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Damage of the endothelial glycocalyx in dialysis patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Loss of the endothelial glycocalyx links albuminuria and vascular dysfunction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Damage of the endothelial glycocalyx in chronic kidney disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Matrix metalloproteinase 9-mediated shedding of syndecan 4 in response to tumor necrosis factor α: a contributor to endothelial cell glycocalyx dysfunction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

An emerging concept of vascular salt sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Vascular endothelium: a vulnerable transit zone for merciless sodium

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Proteolytic Cleavage of the Red Blood Cell Glycocalyx in a Genetic Form of Hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Special article: the endothelial glycocalyx: emerging concepts in pulmonary edema and acute lung injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

The endothelial glycocalyx: an important regulator of the pulmonary vascular barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Glycocalyx degradation causes microvascular perfusion failure in the ex vivo perfused mouse lung: hydroxyethyl starch 130/0.4 pretreatment attenuates this response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

The Role of Heparanase and Sulfatases in the Modification of Heparan Sulfate Proteoglycans within the Tumor Microenvironment and Opportunities for Novel Cancer Therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Tumor attenuation by combined heparan sulfate and polyamine depletion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Genetic alteration of endothelial heparan sulfate selectively inhibits tumor angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Hyaluronan and hyaluronan synthases: potential therapeutic targets in cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Integrin clustering is driven by mechanical resistance from the glycocalyx and the substrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Regulation of growth factor signaling and cell cycle progression by cell adhesion and adhesion-dependent changes in cellular tension

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Integrins in cancer: biological implications and therapeutic opportunities

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Integrin beta1-focal adhesion kinase signaling directs the proliferation of metastatic cancer cells disseminated in the lungs

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

The cancer glycocalyx mechanically primes integrin-mediated growth and survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Functions of cell surface heparan sulfate proteoglycans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Heparan sulphate proteoglycans fine-tune mammalian physiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Syndecans and cell adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Glycome and transcriptome regulation of vasculogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Solution structure of a syndecan-4 cytoplasmic domain and its interaction with phosphatidylinositol 4,5-bisphosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Syndecans: multifunctional cell-surface co-receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

An expression signature of syndecan-1 (CD138), E-cadherin and c-met is associated with factors of angiogenesis and lymphangiogenesis in ductal breast carcinoma in situ

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Targeting of heparanase-modified syndecan-1 by prosecretory mitogen lacritin requires conserved core GAGAL plus heparan and chondroitin sulfate as a novel hybrid binding site that enhances selectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Transmembrane domain-induced oligomerization is crucial for the functions of syndecan-2 and syndecan-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Heparanase deglycanation of syndecan-1 is required for binding of the epithelial-restricted prosecretory mitogen lacritin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

The over-expression of HAS2, Hyal-2 and CD44 is implicated in the invasiveness of breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

The glycocalyx maintains a cell surface pH nanoenvironment crucial for integrin-mediated migration of human melanoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

A low molecular weight heparin inhibits experimental metastasis in mice independently of the endothelial glycocalyx

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Endothelial glycocalyx and coronary vascular permeability: the fringe benefit

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Plasma restoration of endothelial glycocalyx in a rodent model of hemorrhagic shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Registry of the International Society for Heart and Lung Transplantation: twenty-fourth official adult heart transplant report--2007.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Hexosamines, insulin resistance, and the complications of diabetes: current status

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Effect of sulodexide on endothelial glycocalyx and vascular permeability in patients with type 2 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Combined anti-inflammatory and anti-AGE drug treatments have a protective effect on intervertebral discs in mice with diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Standardized Extracts from Hawthorn Leaves and Flowers in the Treatment of Cardiovascular Disorders – Preclinical and Clinical Studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Shear-induced endothelial NOS activation and remodeling via heparan sulfate, glypican-1, and syndecan-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Nanomechanics and sodium permeability of endothelial surface layer modulated by hawthorn extract WS 1442.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Study of the therapeutic benefit of cationic copolymer administration to vascular endothelium under mechanical stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Tumor-associated hyaluronan limits efficacy of monoclonal antibody therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Enzymatic targeting of the stroma ablates physical barriers to treatment of pancreatic ductal adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Antisense inhibition of hyaluronan synthase-2 in human osteosarcoma cells inhibits hyaluronan retention and tumorigenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Inhibition of prostate tumor cell hyaluronan synthesis impairs subcutaneous growth and vascularization in immunocompromised mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Inhibition of oesophageal squamous cell carcinoma progression by in vivo targeting of hyaluronan synthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Inhibitory effect of 4-methylesculetin on hyaluronan synthesis slows the development of human pancreatic cancer in vitro and in nude mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Inhibition of hyaluronan synthesis in breast cancer cells by 4-methylumbelliferone suppresses tumorigenicity in vitro and metastatic lesions of bone in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

A hyaluronan synthase suppressor, 4-methylumbelliferone, inhibits liver metastasis of melanoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Dietary supplement 4-methylumbelliferone: an effective chemopreventive and therapeutic agent for prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Modulation of CD44 Activity by A6-Peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

β-D-xylosides stimulate GAG synthesis in chondrocyte cultures due to elevation of the extracellular GAG domains, accompanied by the depletion of the intra-pericellular GAG pools, with alterations in the GAG profiles

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

A common sugar-nucleotide-mediated mechanism of inhibition of (glycosamino)glycan biosynthesis, as evidenced by 6F-GalNAc (Ac3)

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Interfering with UDP-GlcNAc metabolism and heparan sulfate expression using a sugar analogue reduces angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

Peracetylated 4-fluoro-glucosamine reduces the content and repertoire of N- and O-glycans without direct incorporation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

MicroRNA regulation of proteoglycan function in cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12465

21 January 2018

Identifiers

DOI

10.1111/JOIM.12465

1 reference

5 September 2017

1 reference

PubMed ID

26749537