Visualizing the regulatory role of Angiopoietin-like protein 8 (ANGPTL8) in glucose and lipid metabolic pathways (Q38661812)

5 September 2017

Visualizing the regulatory role of Angiopoietin-like protein 8 (ANGPTL8) in glucose and lipid metabolic pathways (English)

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5 September 2017

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Martina Summer-Kutmon

5

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5 September 2017

9

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5 September 2017

2

Elisa Cirillo

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Chris T. Evelo

8

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Lars Eijssen

6

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Jamil Ahmad

object named as

Jamil Ahmad

7

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Lars Eijssen

6

object named as

Lars M T Eijssen

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5 September 2017

Amnah Siddiqa

1

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PubMed ID

28684091

5 September 2017

Samar H K Tareen

3

1 reference

PubMed ID

28684091

5 September 2017

Amjad Ali

4

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5 September 2017

3 July 2017

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5 September 2017

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Metabolic syndrome pandemic.

5 September 2017

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https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

Global estimates of the prevalence of diabetes for 2010 and 2030

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

The Obesity Epidemic Is a Worldwide Phenomenon

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

A mouse knockout library for secreted and transmembrane proteins.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

Lipasin, a novel nutritionally-regulated liver-enriched factor that regulates serum triglyceride levels

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

Lipasin, thermoregulated in brown fat, is a novel but atypical member of the angiopoietin-like protein family.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

Identification of RIFL, a novel adipocyte-enriched insulin target gene with a role in lipid metabolism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

RETRACTED: Betatrophin: a hormone that controls pancreatic β cell proliferation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

Circulating betatrophin is elevated in patients with type 1 and type 2 diabetes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

The ANGPTL3-4-8 model, a molecular mechanism for triglyceride trafficking

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

Emerging regulation and function of betatrophin

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

Chromosome 19 open reading frame 80 is upregulated by thyroid hormone and modulates autophagy and lipid metabolism.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

Atypical angiopoietin-like protein that regulates ANGPTL3

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

AMP-activated protein kinase suppresses the expression of LXR/SREBP-1 signaling-induced ANGPTL8 in HepG2 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

Angiopoietin-like protein 8 (betatrophin) is a stress-response protein that down-regulates expression of adipocyte triglyceride lipase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

Effects of the antitumor drug OSI-906, a dual inhibitor of IGF-1 receptor and insulin receptor, on the glycemic control, β-cell functions, and β-cell proliferation in male mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

Irisin stimulates browning of white adipocytes through mitogen-activated protein kinase p38 MAP kinase and ERK MAP kinase signaling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

The Arg59Trp variant in ANGPTL8 (betatrophin) is associated with total and HDL-cholesterol in American Indians and Mexican Americans and differentially affects cleavage of ANGPTL3.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

The Reactome pathway knowledgebase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

A network biology workflow to study transcriptomics data of the diabetic liver

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

PathVisio 3: an extendable pathway analysis toolbox

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

Presenting and exploring biological pathways with PathVisio

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

Betatrophin provides a new insight into diabetes treatment and lipid metabolism (Review).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

Are animal models as good as we think?

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

Comparative aspects of rodent and nonrodent animal models for mechanistic and translational diabetes research

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

Animal models of human disease: challenges in enabling translation

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

Animal models: inside the minds of mice and men.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

A dual role of lipasin (betatrophin) in lipid metabolism and glucose homeostasis: consensus and controversy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

ANGPTL8/Betatrophin R59W variant is associated with higher glucose level in non-diabetic Arabs living in Kuwaits.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

Association of the angiopoietin-like protein 8 rs2278426 polymorphism and several environmental factors with serum lipid levels

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

A null mutation in ANGPTL8 does not associate with either plasma glucose or type 2 diabetes in humans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

Angiopoietin-Like Proteins: A Comprehensive Look

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

Inhibitory receptors bind ANGPTLs and support blood stem cells and leukaemia development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

Resolving Discrepant Findings on ANGPTL8 in β-Cell Proliferation: A Collaborative Approach to Resolving the Betatrophin Controversy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

Structural characterization of ANGPTL8 (betatrophin) with its interacting partner lipoprotein lipase.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

A highly conserved motif within the NH2-terminal coiled-coil domain of angiopoietin-like protein 4 confers its inhibitory effects on lipoprotein lipase by disrupting the enzyme dimerization.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

Proteomics. Tissue-based map of the human proteome

7 January 2021

2 references

https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

7 January 2021

https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

inferred from DOI database lookup

7 January 2021

based on heuristic

Mice lacking ANGPTL8 (Betatrophin) manifest disrupted triglyceride metabolism without impaired glucose homeostasis

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

Higher plasma betatrophin/ANGPTL8 level in Type 2 Diabetes subjects does not correlate with blood glucose or insulin resistance.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

Circulating betatrophin correlates with atherogenic lipid profiles but not with glucose and insulin levels in insulin-resistant individuals

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

Elevated mouse hepatic betatrophin expression does not increase human β-cell replication in the transplant setting

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

ANGPTL8/betatrophin does not control pancreatic beta cell expansion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

In vivo targeted delivery of ANGPTL8 gene for beta cell regeneration in rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

Integrated expression profiling and genome-wide analysis of ChREBP targets reveals the dual role for ChREBP in glucose-regulated gene expression.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

Thyroid hormone crosstalk with nuclear receptor signaling in metabolic regulation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

Coupling between Nutrient Availability and Thyroid Hormone Activation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

A pathway approach to investigate the function and regulation of SREBPs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

Expression and function of the insulin receptor substrate proteins in cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

The phosphoinositide 3-kinase pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

Mechanism of activation of protein kinase B by insulin and IGF-1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

A Positive Feedback Loop between Akt and mTORC2 via SIN1 Phosphorylation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

FoxO proteins in insulin action and metabolism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

Interplay between FOXO, TOR, and Akt.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

FoxOs inhibit mTORC1 and activate Akt by inducing the expression of Sestrin3 and Rictor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

Cellular mechanisms of insulin resistance: role of stress-regulated serine kinases and insulin receptor substrates (IRS) serine phosphorylation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

AMPK-associated signaling to bridge the gap between fuel metabolism and hepatocyte viability

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

MicroRNA hsa-miR-613 targets the human LXRα gene and mediates a feedback loop of LXRα autoregulation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

Insulin signalling and the regulation of glucose and lipid metabolism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

Transcriptional regulation of hepatic lipogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

Cross-regulation of hepatic glucose metabolism via ChREBP and nuclear receptors.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

Thyroid hormone regulation of metabolism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGENO.2017.06.006

WikiPathways: capturing the full diversity of pathway knowledge

7 January 2021

1 reference

COCI

https://opencitations.net/index/api/v1/citations/10.1093/NAR/GKV1024

10.1016/J.YGENO.2017.06.006

13 January 2024

Identifiers

DOI

1 reference

5 September 2017

1 reference

PubMed ID

28684091