The story of HCC in NAFLD: from epidemiology, across pathogenesis, to prevention and treatment (Q38645975)

5 September 2017

The story of HCC in NAFLD: from epidemiology, across pathogenesis, to prevention and treatment (English)

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5 September 2017

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hepatocellular carcinoma

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Cristina Margini

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PubMed ID

26601627

5 September 2017

Jean F Dufour

series ordinal

2

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5 September 2017

25 November 2015

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5 September 2017

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5 September 2017

36

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5 September 2017

317-324

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5 September 2017

3

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5 September 2017

Global cancer statistics

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21 January 2018

Hepatocellular carcinoma

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Prospective analysis of risk factors for hepatocellular carcinoma in patients with liver cirrhosis

21 January 2018

1 reference

Association between nonalcoholic fatty liver disease and risk for hepatocellular cancer, based on systematic review

21 January 2018

1 reference

Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms

21 January 2018

1 reference

Overweight, Obesity, and Mortality from Cancer in a Prospectively Studied Cohort of U.S. Adults

21 January 2018

1 reference

Effects of excess weight on cancer incidences depending on cancer sites and histologic findings among men: Korea National Health Insurance Corporation Study.

21 January 2018

1 reference

Relation of body mass index to cancer risk in 362,552 Swedish men.

21 January 2018

1 reference

Metabolic risk factors and primary liver cancer in a prospective study of 578,700 adults

21 January 2018

1 reference

Abdominal obesity, weight gain during adulthood and risk of liver and biliary tract cancer in a European cohort.

21 January 2018

1 reference

Metabolic syndrome and hepatocellular carcinoma risk

21 January 2018

1 reference

Excess risk of primary liver cancer in patients with diabetes mellitus

21 January 2018

1 reference

The role of diabetes in hepatocellular carcinoma: a case-control study among United States Veterans

21 January 2018

1 reference

Diabetes increases the risk of chronic liver disease and hepatocellular carcinoma

21 January 2018

1 reference

Non-alcoholic steatohepatitis and cancer

21 January 2018

1 reference

Expanding the natural history of nonalcoholic steatohepatitis: from cryptogenic cirrhosis to hepatocellular carcinoma.

21 January 2018

1 reference

Prevalence of obesity and diabetes in patients with cryptogenic cirrhosis: a case-control study

21 January 2018

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The natural history of nonalcoholic steatohepatitis: a follow-up study of forty-two patients for up to 21 years

21 January 2018

1 reference

Cryptogenic cirrhosis: clinical characterization and risk factors for underlying disease

21 January 2018

1 reference

NAFLD, NASH and liver cancer

21 January 2018

1 reference

Metabolic syndrome and hepatocellular carcinoma: two growing epidemics with a potential link

21 January 2018

1 reference

Hepatocellular carcinoma pathogenesis: from genes to environment

21 January 2018

1 reference

Obesity-associated mechanisms of hepatocarcinogenesis

21 January 2018

1 reference

Non-alcoholic fatty liver disease as a risk factor for hepatocellular carcinoma: mechanisms and implications

21 January 2018

1 reference

Concomitant activation of the JAK/STAT, PI3K/AKT, and ERK signaling is involved in leptin-mediated promotion of invasion and migration of hepatocellular carcinoma cells

21 January 2018

1 reference

Leptin receptor-mediated signaling regulates hepatic fibrogenesis and remodeling of extracellular matrix in the rat.

21 January 2018

1 reference

The role of adiponectin in cancer: a review of current evidence

21 January 2018

1 reference

Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: lessons from genetically engineered mice

21 January 2018

1 reference

Unsaturated fatty acids promote hepatoma proliferation and progression through downregulation of the tumor suppressor PTEN.

21 January 2018

1 reference

Hyperinsulinaemia and insulin signalling in the pathogenesis and the clinical course of hepatocellular carcinoma.

21 January 2018

1 reference

The gut microbiota and obesity: from correlation to causality

21 January 2018

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Metabolic endotoxemia initiates obesity and insulin resistance

21 January 2018

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Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome

21 January 2018

1 reference

Promotion of hepatocellular carcinoma by the intestinal microbiota and TLR4.

21 January 2018

1 reference

Increased duodenal iron absorption through up-regulation of divalent metal transporter 1 from enhancement of iron regulatory protein 1 activity in patients with nonalcoholic steatohepatitis.

21 January 2018

1 reference

21 January 2018

The genetics of NAFLD.

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Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease

21 January 2018

1 reference

PNPLA3 I148M (rs738409) genetic variant is associated with hepatocellular carcinoma in obese individuals

21 January 2018

1 reference

Carriage of the PNPLA3 rs738409 C >G polymorphism confers an increased risk of non-alcoholic fatty liver disease associated hepatocellular carcinoma.

21 January 2018

1 reference

PNPLA3 has retinyl-palmitate lipase activity in human hepatic stellate cells

21 January 2018

1 reference

Nonalcoholic steatohepatitis and noncirrhotic hepatocellular carcinoma: fertile soil

21 January 2018

1 reference

Hepatocellular carcinoma in non-alcoholic fatty liver disease: an emerging menace

21 January 2018

1 reference

Hepatocellular carcinoma in patients with nonalcoholic fatty liver disease: helical CT and MR imaging findings with clinical-pathologic comparison

21 January 2018

1 reference

Characterization and prognosis of patients with hepatocellular carcinoma (HCC) in the non-cirrhotic liver

21 January 2018

1 reference

Characteristics of hepatocellular carcinoma in cirrhotic and non-cirrhotic non-alcoholic fatty liver disease

21 January 2018

1 reference

Non-alcoholic fatty liver disease contributes to hepatocarcinogenesis in non-cirrhotic liver: a clinical and pathological study

21 January 2018

1 reference

Changing epidemiology of hepatocellular adenoma in the United States: review of the literature

21 January 2018

1 reference

Temporal trends of nonalcoholic fatty liver disease-related hepatocellular carcinoma in the veteran affairs population

21 January 2018

1 reference

Management of hepatocellular carcinoma: An update

21 January 2018

1 reference

Dietary preference, physical activity, and cancer risk in men: national health insurance corporation study

21 January 2018

1 reference

Regular exercise decreases liver tumors development in hepatocyte-specific PTEN-deficient mice independently of steatosis

21 January 2018

1 reference

Effect of nonmotorized wheel running on mammary carcinogenesis: circulating biomarkers, cellular processes, and molecular mechanisms in rats

21 January 2018

1 reference

Plasma levels of vitamin E and carotenoids are decreased in patients with Nonalcoholic Steatohepatitis (NASH).

21 January 2018

1 reference

Prediagnostic circulating vitamin D levels and risk of hepatocellular carcinoma in European populations: a nested case-control study

21 January 2018

1 reference

Mediterranean diet and hepatocellular carcinoma

21 January 2018

1 reference

Statin use and non-alcoholic steatohepatitis in at risk individuals.

21 January 2018

1 reference

Statins are associated with a reduced risk of hepatocellular carcinoma in a large cohort of patients with diabetes

21 January 2018

1 reference

Type 2 diabetes increases and metformin reduces total, colorectal, liver and pancreatic cancer incidences in Taiwanese: a representative population prospective cohort study of 800,000 individuals

21 January 2018

1 reference

Metformin decreases hepatocellular carcinoma risk in a dose-dependent manner: population-based and in vitro studies

21 January 2018

1 reference

Anti-diabetic medications and the risk of hepatocellular cancer: a systematic review and meta-analysis

21 January 2018

1 reference

Metformin and reduced risk of hepatocellular carcinoma in diabetic patients: a meta-analysis.

21 January 2018

1 reference

Risk of hepatocellular carcinoma in diabetic patients and risk reduction associated with anti-diabetic therapy: a population-based cohort study

21 January 2018

1 reference

Prognostic significance of AMPK activation and therapeutic effects of metformin in hepatocellular carcinoma

21 January 2018

1 reference

Metformin prevents liver tumorigenesis by inhibiting pathways driving hepatic lipogenesis.

21 January 2018

1 reference

Continuation of metformin use after a diagnosis of cirrhosis significantly improves survival of patients with diabetes

21 January 2018

1 reference

Diabetes mellitus, insulin treatment, diabetes duration, and risk of biliary tract cancer and hepatocellular carcinoma in a European cohort

21 January 2018

1 reference

Antidiabetic therapy and increased risk of hepatocellular carcinoma in chronic liver disease

21 January 2018

1 reference

EASL-EORTC clinical practice guidelines: management of hepatocellular carcinoma

21 January 2018

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Outcomes of curative treatment for hepatocellular cancer in nonalcoholic steatohepatitis versus hepatitis C and alcoholic liver disease.

21 January 2018

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Fatty liver in liver transplantation and surgery

21 January 2018

1 reference

Treatment and survival of non-alcoholic steatohepatitis associated hepatocellular carcinoma

21 January 2018

1 reference

Role of iron in hepatocellular carcinoma

21 January 2018

1 reference

Changing trends in malignant transformation of hepatocellular adenoma

21 January 2018

1 reference

Epidemiology of Hepatocellular Carcinoma

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1111/LIV.13031

1 reference

5 September 2017

1 reference

PubMed ID

26601627