Macrophage-derived lipid agonists of PPAR-α as intrinsic controllers of inflammation (Q38639002)

5 September 2017

Macrophage-derived lipid agonists of PPAR-α as intrinsic controllers of inflammation (English)

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5 September 2017

Silvia Pontis

1

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5 September 2017

Alison Ribeiro

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2

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5 September 2017

Oscar Sasso

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3

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5 September 2017

Daniele Piomelli

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4

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5 September 2017

20 November 2015

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Critical Reviews in Biochemistry and Molecular Biology

5 September 2017

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5 September 2017

51

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5 September 2017

7-14

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5 September 2017

1

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N-Acylethanolamine-hydrolyzing acid amidase inhibition increases colon N-palmitoylethanolamine levels and counteracts murine colitis

5 September 2017

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

Harnessing the anti-inflammatory potential of palmitoylethanolamide.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

β-Lactones Inhibit N-acylethanolamine Acid Amidase by S-Acylation of the Catalytic N-Terminal Cysteine

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

The cloned rat hydrolytic enzyme responsible for the breakdown of anandamide also catalyzes its formation via the condensation of arachidonic acid and ethanolamine.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

Advances in the discovery of N-acylethanolamine acid amidase inhibitors

21 January 2018

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https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

R-flurbiprofen reduces neuropathic pain in rodents by restoring endogenous cannabinoids

21 January 2018

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https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

Peroxisome proliferator-activated receptors in the cardiovascular system

21 January 2018

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https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

21 January 2018

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https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat

21 January 2018

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https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

Inhibitory effect of palmitoylethanolamide on gastrointestinal motility in mice

21 January 2018

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https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

The role of endogenous and exogenous ligands for the peroxisome proliferator-activated receptor alpha (PPAR-alpha) in the regulation of inflammation in macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

Adelmidrol, a palmitoylethanolamide analogue, reduces chronic inflammation in a carrageenin-granuloma model in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

Levels of endocannabinoids and palmitoylethanolamide and their pharmacological manipulation in chronic granulomatous inflammation in rats

21 January 2018

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https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

Oleylethanolamide regulates feeding and body weight through activation of the nuclear receptor PPAR-alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

The endocannabinoid system is modulated in response to spinal cord injury in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

Activation of mitogen-activated protein kinases by peroxisome proliferator-activated receptor ligands: an example of nongenomic signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

Activation of peroxisome proliferator-activated receptor-alpha decreases endothelin-1-induced p38 mitogen-activated protein kinase activation in cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

Inhibitory effect of cannabichromene, a major non-psychotropic cannabinoid extracted from Cannabis sativa, on inflammation-induced hypermotility in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

Immunology's foundation: the 100-year anniversary of the Nobel Prize to Paul Ehrlich and Elie Metchnikoff

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

The role of lipid-activated nuclear receptors in shaping macrophage and dendritic cell function: From physiology to pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors alpha and gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

An overview on biological mechanisms of PPARs.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

Macrophages and tissue injury: agents of defense or destruction?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

Inactivation of N-acyl phosphatidylethanolamine phospholipase D reveals multiple mechanisms for the biosynthesis of endocannabinoids

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

A biosynthetic pathway for anandamide

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

Rapid broad-spectrum analgesia through activation of peroxisome proliferator-activated receptor-alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

The search for the palmitoylethanolamide receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

Structure of human N-acylphosphatidylethanolamine-hydrolyzing phospholipase D: regulation of fatty acid ethanolamide biosynthesis by bile acids

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

Palmitoylethanolamide stimulation induces allopregnanolone synthesis in C6 Cells and primary astrocytes: involvement of peroxisome-proliferator activated receptor-α.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

Palmitoylethanolamide prevents metabolic alterations and restores leptin sensitivity in ovariectomized rats

21 January 2018

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https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

Structure and function of fatty acid amide hydrolase

21 January 2018

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https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

Nuclear hormone receptors enable macrophages and dendritic cells to sense their lipid environment and shape their immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

Molecular characterization of a phospholipase D generating anandamide and its congeners

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

Treatment in vitro with PPARα and PPARγ ligands drives M1-to-M2 polarization of macrophages from T. cruzi-infected mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

Changes in spinal and supraspinal endocannabinoid levels in neuropathic rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

Synthesis and structure-activity relationship (SAR) of 2-methyl-4-oxo-3-oxetanylcarbamic acid esters, a class of potent N-acylethanolamine acid amidase (NAAA) inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

A Potent Systemically Active N-Acylethanolamine Acid Amidase Inhibitor that Suppresses Inflammation and Human Macrophage Activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

Characterisation of the cannabinoid receptor system in synovial tissue and fluid in patients with osteoarthritis and rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

Regulation of macrophage functions by PPAR-alpha, PPAR-gamma, and LXRs in mice and men.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

Rapid non-genomic regulation of Ca2+ signals and insulin secretion by PPAR alpha ligands in mouse pancreatic islets of Langerhans

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

Antinociceptive effects of the N-acylethanolamine acid amidase inhibitor ARN077 in rodent pain models

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

Synthesis and biological evaluation of new potential inhibitors of N-acylethanolamine hydrolyzing acid amidase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

Release of fatty acid amides in a patient with hemispheric stroke: a microdialysis study

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

Macrophage plasticity and polarization: in vivo veritas

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

Anandamide biosynthesis catalyzed by the phosphodiesterase GDE1 and detection of glycerophospho-N-acyl ethanolamine precursors in mouse brain

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

Endocannabinoid biosynthesis proceeding through glycerophospho-N-acyl ethanolamine and a role for alpha/beta-hydrolase 4 in this pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

Mast cells, glia and neuroinflammation: partners in crime?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

Selective N-acylethanolamine-hydrolyzing acid amidase inhibition reveals a key role for endogenous palmitoylethanolamide in inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

Ulcerative colitis impairs the acylethanolamide-based anti-inflammatory system reversal by 5-aminosalicylic acid and glucocorticoids

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

Biosynthesis of anandamide and N-palmitoylethanolamine by sequential actions of phospholipase A2 and lysophospholipase D

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

Biosynthetic pathways of bioactive N-acylethanolamines in brain

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

Molecular characterization of N-acylethanolamine-hydrolyzing acid amidase, a novel member of the choloylglycine hydrolase family with structural and functional similarity to acid ceramidase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

N-cyclohexanecarbonylpentadecylamine: a selective inhibitor of the acid amidase hydrolysing N-acylethanolamines, as a tool to distinguish acid amidase from fatty acid amide hydrolase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

Predominant expression of lysosomal N-acylethanolamine-hydrolyzing acid amidase in macrophages revealed by immunochemical studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

An acid amidase hydrolyzing anandamide as an endogenous ligand for cannabinoid receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

Functional analysis of the purified anandamide-generating phospholipase D as a member of the metallo-beta-lactamase family

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

Proinflammatory stimuli control N-acylphosphatidylethanolamine-specific phospholipase D expression in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

Induction of IκBα Expression as a Mechanism Contributing to the Anti-inflammatory Activities of Peroxisome Proliferator-activated Receptor-α Activators

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2015.1092944

10.3109/10409238.2015.1092944

21 January 2018

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DOI

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5 September 2017

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