Gamma-aminobutyric acid (GABA) and pentobarbital induce different conformational rearrangements in the GABA A receptor alpha1 and beta2 pre-M1 regions (Q38631543)

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scientific article published on 03 April 2008

Language	Label	Description	Also known as
English	Gamma-aminobutyric acid (GABA) and pentobarbital induce different conformational rearrangements in the GABA A receptor alpha1 and beta2 pre-M1 regions	scientific article published on 03 April 2008

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

Gamma-aminobutyric acid (GABA) and pentobarbital induce different conformational rearrangements in the GABA A receptor alpha1 and beta2 pre-M1 regions (English)

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

author name string

Jose Mercado

1

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

Cynthia Czajkowski

2

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

language of work or name

0 references

publication date

3 April 2008

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Europe PubMed Central

PMC publication ID

4 September 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

283

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

22

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

15250-15257

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

Mapping the contribution of beta3-containing GABAA receptors to volatile and intravenous general anesthetic actions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2397470

6 September 2017

Channel opening by anesthetics and GABA induces similar changes in the GABAA receptor M2 segment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2397470

6 September 2017

Mutational analysis of molecular requirements for the actions of general anaesthetics at the gamma-aminobutyric acidA receptor subtype, alpha1beta2gamma2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2397470

6 September 2017

ON THE NATURE OF ALLOSTERIC TRANSITIONS: A PLAUSIBLE MODEL

1 reference

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6 September 2017

Structure and dynamics of the GABA binding pocket: A narrowing cleft that constricts during activation.

1 reference

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6 September 2017

General anaesthetic action at transmitter-gated inhibitory amino acid receptors

1 reference

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6 September 2017

State-dependent accessibility and electrostatic potential in the channel of the acetylcholine receptor. Inferences from rates of reaction of thiosulfonates with substituted cysteines in the M2 segment of the alpha subunit

1 reference

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The interaction of the general anesthetic etomidate with the gamma-aminobutyric acid type A receptor is influenced by a single amino acid

1 reference

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6 September 2017

Sites of alcohol and volatile anaesthetic action on GABA(A) and glycine receptors.

1 reference

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6 September 2017

Direct activation of GABAA receptors by barbiturates in cultured rat hippocampal neurons

1 reference

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6 September 2017

Kinetic properties and regulation of GABAA receptor channels

1 reference

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6 September 2017

Modes and models of GABA(A) receptor gating

1 reference

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Drug interactions at the GABA receptor-ionophore complex

1 reference

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14 September 2017

Molecular determinants for the action of general anesthetics at recombinant alpha(2)beta(3)gamma(2)gamma-aminobutyric acid(A) receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2397470

25 September 2017

Mapping the conformational wave of acetylcholine receptor channel gating

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2397470

25 September 2017

Role of the conserved lysine residue in the middle of the predicted extracellular loop between M2 and M3 in the GABA(A) receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2397470

25 September 2017

Molecular dissection of benzodiazepine binding and allosteric coupling using chimeric gamma-aminobutyric acidA receptor subunits.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2397470

25 September 2017

Positive modulation of human gamma-aminobutyric acid type A and glycine receptors by the inhalation anesthetic isoflurane

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2397470

23 June 2018

GABAA receptor needs two homologous domains of the beta-subunit for activation by GABA but not by pentobarbital.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2397470

23 June 2018

Barbiturate regulation of kinetic properties of the GABAA receptor channel of mouse spinal neurones in culture

1 reference

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23 June 2018

Subunit stoichiometry of a mammalian K+ channel determined by construction of multimeric cDNAs.

1 reference

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23 June 2018

Identification of a GABAA receptor anesthetic binding site at subunit interfaces by photolabeling with an etomidate analog.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708638200

21 January 2018

Complementary regulation of anaesthetic activation of human (alpha6beta3gamma2L) and Drosophila (RDL) GABA receptors by a single amino acid residue.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708638200

21 January 2018

Principal pathway coupling agonist binding to channel gating in nicotinic receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708638200

21 January 2018

Gating dynamics of the acetylcholine receptor extracellular domain.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708638200

21 January 2018

Charged residues in the alpha1 and beta2 pre-M1 regions involved in GABAA receptor activation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708638200

21 January 2018

Potassium currents expressed from Drosophila and mouse eag cDNAs in Xenopus oocytes.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708638200

21 January 2018

Different residues in the GABA(A) receptor alpha 1T60-alpha 1K70 region mediate GABA and SR-95531 actions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708638200

21 January 2018

Defining the propofol binding site location on the GABAA receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708638200

21 January 2018

The GABAA receptor alpha 1 subunit Pro174-Asp191 segment is involved in GABA binding and channel gating

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708638200

21 January 2018

Mutation of glutamate 155 of the GABAA receptor beta2 subunit produces a spontaneously open channel: a trigger for channel activation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708638200

21 January 2018

Agonist-, antagonist-, and benzodiazepine-induced structural changes in the alpha1 Met113-Leu132 region of the GABAA receptor.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708638200

21 January 2018

A single hydrophobic residue confers barbiturate sensitivity to gamma-aminobutyric acid type C receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2397470

31 August 2018

Inhibition of rho1 receptor GABAergic currents by alcohols and volatile anesthetics.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2397470

31 August 2018

Structural domains of the human GABAA receptor 3 subunit involved in the actions of pentobarbital

1 reference

https://pubmed.ncbi.nlm.nih.gov/18387955

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

(-)Pentobarbital opens ion channels of long duration in cultured mouse spinal neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/18387955

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Single channel currents activated by gamma-aminobutyric acid, muscimol, and (-)-pentobarbital in cultured mouse spinal neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/18387955

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M708638200

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

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