Fcγ receptor pathways during active and passive immunization (Q38615357)

4 September 2017

Fcγ receptor pathways during active and passive immunization (English)

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4 September 2017

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2

Jeffrey V Ravetch

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4 September 2017

1

Stylianos Bournazos

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4 September 2017

1 November 2015

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4 September 2017

Immunological Reviews

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4 September 2017

268

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4 September 2017

1

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4 September 2017

88-103

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Novel roles for the IgG Fc glycan

4 September 2017

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Revisiting the role of glycosylation in the structure of human IgG Fc.

21 January 2018

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General mechanism for modulating immunoglobulin effector function

21 January 2018

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Type I and type II Fc receptors regulate innate and adaptive immunity

21 January 2018

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Structural Characterization of Anti-Inflammatory Immunoglobulin G Fc Proteins

21 January 2018

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21 January 2018

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Analysis of the antibody structure based on high-resolution crystallographic studies

21 January 2018

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Structural analysis of human IgG-Fc glycoforms reveals a correlation between glycosylation and structural integrity

21 January 2018

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IgG2 Fc structure and the dynamic features of the IgG CH2-CH3 interface

21 January 2018

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Impact of differential glycosylation on IgG activity

21 January 2018

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In vivo enzymatic modulation of IgG glycosylation inhibits autoimmune disease in an IgG subclass-dependent manner

21 January 2018

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Divergent immunoglobulin g subclass activity through selective Fc receptor binding

21 January 2018

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Agalactosylated IgG antibodies depend on cellular Fc receptors for in vivo activity.

21 January 2018

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High resolution mapping of the binding site on human IgG1 for Fc gamma RI, Fc gamma RII, Fc gamma RIII, and FcRn and design of IgG1 variants with improved binding to the Fc gamma R.

21 January 2018

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The 3.2-A crystal structure of the human IgG1 Fc fragment-Fc gammaRIII complex

21 January 2018

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Fc-engineered anti-CD40 antibody enhances multiple effector functions and exhibits potent in vitro and in vivo antitumor activity against hematologic malignancies

21 January 2018

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Optimization of antibody binding to FcgammaRIIa enhances macrophage phagocytosis of tumor cells

21 January 2018

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Mouse model recapitulating human Fcγ receptor structural and functional diversity

21 January 2018

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Broadly neutralizing anti-HIV-1 antibodies require Fc effector functions for in vivo activity

21 January 2018

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Human IgG Fc domain engineering enhances antitoxin neutralizing antibody activity

21 January 2018

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Differential Fc-Receptor Engagement Drives an Anti-tumor Vaccinal Effect

21 January 2018

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Inhibitory Fcγ receptor engagement drives adjuvant and anti-tumor activities of agonistic CD40 antibodies

21 January 2018

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Unique carbohydrate-carbohydrate interactions are required for high affinity binding between Fc RIII and antibodies lacking core fucose

21 January 2018

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The absence of fucose but not the presence of galactose or bisecting N-acetylglucosamine of human IgG1 complex-type oligosaccharides shows the critical role of enhancing antibody-dependent cellular cytotoxicity

21 January 2018

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Engineered anti-CD20 antibodies with enhanced complement-activating capacity mediate potent anti-lymphoma activity

21 January 2018

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Lack of fucose on human IgG1 N-linked oligosaccharide improves binding to human Fcgamma RIII and antibody-dependent cellular toxicity

21 January 2018

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Obinutuzumab plus Chlorambucil in Patients with CLL and Coexisting Conditions

21 January 2018

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Glycan variants of a respiratory syncytial virus antibody with enhanced effector function and in vivo efficacy

21 January 2018

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Recapitulation of IVIG anti-inflammatory activity with a recombinant IgG Fc.

21 January 2018

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Anti-Inflammatory Activity of Immunoglobulin G Resulting from Fc Sialylation

21 January 2018

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Anti-HA Glycoforms Drive B Cell Affinity Selection and Determine Influenza Vaccine Efficacy

21 January 2018

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Immunoglobulin G galactosylation and sialylation are associated with pregnancy-induced improvement of rheumatoid arthritis and the postpartum flare: results from a large prospective cohort study

21 January 2018

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Glycan profiling of anti-citrullinated protein antibodies isolated from human serum and synovial fluid

21 January 2018

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Functional and clinical consequences of Fc receptor polymorphic and copy number variants.

21 January 2018

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Fcgamma receptors: old friends and new family members

21 January 2018

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Fcgamma receptors as regulators of immune responses

21 January 2018

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Organization of the human and mouse low-affinity Fc gamma R genes: duplication and recombination

21 January 2018

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Genomic organization of classical human low-affinity Fcgamma receptor genes

21 January 2018

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Fcγ receptors: genetic variation, function, and disease.

21 January 2018

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Structural basis for binding of human IgG1 to its high-affinity human receptor FcγRI.

21 January 2018

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Association of the high-affinity receptor for IgG (Fc gamma RI) with the gamma subunit of the IgE receptor

21 January 2018

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Molecular basis for immune complex recognition: a comparison of Fc-receptor structures

21 January 2018

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A complementary DNA clone for a macrophage-lymphocyte Fc receptor.

21 January 2018

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Structure and expression of human IgG FcRII(CD32). Functional heterogeneity is encoded by the alternatively spliced products of multiple genes

21 January 2018

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Allelic polymorphisms in the FcgammaRIIC gene can influence its function on normal human natural killer cells

21 January 2018

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Mechanisms for regulating expression of membrane isoforms of Fc gamma RIII (CD16).

21 January 2018

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CR3 (Mac-1, alpha M beta 2, CD11b/CD18) and Fc gamma RIII cooperate in generation of a neutrophil respiratory burst: requirement for Fc gamma RIII and tyrosine phosphorylation

21 January 2018

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Function of human Fc gamma RIIA and Fc gamma RIIIB.

21 January 2018

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The coordination of signaling during Fc receptor-mediated phagocytosis

21 January 2018

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Tyrosine-containing motif that transduces cell activation signals also determines internalization and antigen presentation via type III receptors for IgG

21 January 2018

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Engagement of the high-affinity IgE receptor activates src protein-related tyrosine kinases

21 January 2018

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A 77-kDa protein associates with pp125FAK in mast cells and becomes tyrosine-phosphorylated by high affinity IgE receptor aggregation

21 January 2018

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Fcgamma receptor-mediated mitogen-activated protein kinase activation in monocytes is independent of Ras.

21 January 2018

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Phosphatidylinositol-3 kinase activation induced upon Fc gamma RIIIA-ligand interaction

21 January 2018

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Activation and expression of the nuclear factors of activated T cells, NFATp and NFATc, in human natural killer cells: regulation upon CD16 ligand binding

21 January 2018

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Cytoplasmic domain heterogeneity and functions of IgG Fc receptors in B lymphocytes

21 January 2018

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Role of the inositol phosphatase SHIP in negative regulation of the immune system by the receptor Fc(gamma)RIIB.

21 January 2018

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Deletion of SHIP or SHP-1 reveals two distinct pathways for inhibitory signaling

21 January 2018

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B cells and CD22 are dispensable for the immediate antiinflammatory activity of intravenous immunoglobulins in vivo

21 January 2018

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Intravenous immunoglobulin therapy: how does IgG modulate the immune system?

21 January 2018

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Identification of a receptor required for the anti-inflammatory activity of IVIG.

21 January 2018

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Intravenous gammaglobulin suppresses inflammation through a novel T(H)2 pathway.

21 January 2018

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Protection in antibody- and T cell-mediated autoimmune diseases by antiinflammatory IgG Fcs requires type II FcRs

21 January 2018

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Two species of human Fc epsilon receptor II (Fc epsilon RII/CD23): tissue-specific and IL-4-specific regulation of gene expression

21 January 2018

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21 January 2018

12 December 2020

Crystal structure of IgE bound to its B-cell receptor CD23 reveals a mechanism of reciprocal allosteric inhibition with high affinity receptor Fc RI

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The absence of IgE antibody-mediated augmentation of immune responses in CD23-deficient mice

21 January 2018

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IgE-mediated enhancement of CD4+ T cell responses in mice requires antigen presentation by CD11c+ cells and not by B cells

21 January 2018

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Therapeutic antibodies for autoimmunity and inflammation

21 January 2018

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Antibodies, Fc receptors and cancer

21 January 2018

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Immune modulation in cancer with antibodies

21 January 2018

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Effect of palivizumab prophylaxis on subsequent recurrent wheezing in preterm infants

21 January 2018

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Sustained protection against Ebola virus infection following treatment of infected nonhuman primates with ZMAb

21 January 2018

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Raxibacumab for the treatment of inhalational anthrax

21 January 2018

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A critical review of the role of Fc gamma receptor polymorphisms in the response to monoclonal antibodies in cancer

21 January 2018

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Immunoglobulin G fragment C receptor polymorphisms and clinical efficacy of trastuzumab-based therapy in patients with HER-2/neu-positive metastatic breast cancer.

21 January 2018

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Two immunoglobulin G fragment C receptor polymorphisms independently predict response to rituximab in patients with follicular lymphoma

21 January 2018

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FCGR2A and FCGR3A polymorphisms associated with clinical outcome of epidermal growth factor receptor expressing metastatic colorectal cancer patients treated with single-agent cetuximab.

21 January 2018

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Impact of Fc{gamma}RIIa-Fc{gamma}RIIIa polymorphisms and KRAS mutations on the clinical outcome of patients with metastatic colorectal cancer treated with cetuximab plus irinotecan.

21 January 2018

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A requirement for FcγR in antibody-mediated bacterial toxin neutralization

21 January 2018

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Broadly neutralizing hemagglutinin stalk-specific antibodies require FcγR interactions for protection against influenza virus in vivo

21 January 2018

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FcγRIV deletion reveals its central role for IgG2a and IgG2b activity in vivo

21 January 2018

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A serotype 3 pneumococcal capsular polysaccharide-specific monoclonal antibody requires Fcγ receptor III and macrophages to mediate protection against pneumococcal pneumonia in mice

21 January 2018

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Isotype switching increases efficacy of antibody protection against staphylococcal enterotoxin B-induced lethal shock and Staphylococcus aureus sepsis in mice

21 January 2018

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Fc receptor but not complement binding is important in antibody protection against HIV.

21 January 2018

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Broadly neutralizing antibodies and viral inducers decrease rebound from HIV-1 latent reservoirs in humanized mice

21 January 2018

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A neutralizing antibody selected from plasma cells that binds to group 1 and group 2 influenza A hemagglutinins

21 January 2018

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Diversity considerations in HIV-1 vaccine selection

21 January 2018

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Evolutionary and immunological implications of contemporary HIV-1 variation.

21 January 2018

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A Blueprint for HIV Vaccine Discovery

21 January 2018

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Evolution of an HIV glycan-dependent broadly neutralizing antibody epitope through immune escape

21 January 2018

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Human immunodeficiency virus type 1 elite neutralizers: individuals with broad and potent neutralizing activity identified by using a high-throughput neutralization assay together with an analytical selection algorithm

21 January 2018

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Antibodies in HIV-1 vaccine development and therapy

21 January 2018

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Protection of macaques against vaginal transmission of a pathogenic HIV-1/SIV chimeric virus by passive infusion of neutralizing antibodies

21 January 2018

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Antibody-based protection against HIV infection by vectored immunoprophylaxis

21 January 2018

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HIV-1 suppression and durable control by combining single broadly neutralizing antibodies and antiretroviral drugs in humanized mice

21 January 2018

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HIV therapy by a combination of broadly neutralizing antibodies in humanized mice.

21 January 2018

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Viraemia suppressed in HIV-1-infected humans by broadly neutralizing antibody 3BNC117.

21 January 2018

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FcgammaRIIa genotype predicts progression of HIV infection.

21 January 2018

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A mouse model for HIV-1 entry

21 January 2018

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Antibody isotype-specific engagement of Fcgamma receptors regulates B lymphocyte depletion during CD20 immunotherapy.

21 January 2018

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The innate mononuclear phagocyte network depletes B lymphocytes through Fc receptor-dependent mechanisms during anti-CD20 antibody immunotherapy

21 January 2018

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Inhibitory Fc receptors modulate in vivo cytotoxicity against tumor targets

21 January 2018

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The use of immune complex vaccines to enhance antibody responses against neutralizing epitopes on HIV-1 envelope gp120.

21 January 2018

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Inactivated Venezuelan Equine Encephalomyelitis Virus Vaccine Complexed with Specific Antibody: Enhanced Primary Immune Response and Altered Pattern of Antibody Class Elicited

21 January 2018

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Improving immunogenicity of HIV-1 envelope gp120 by glycan removal and immune complex formation

21 January 2018

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Elicitation of broadly reactive antibodies against glycan-modulated neutralizing V3 epitopes of HIV-1 by immune complex vaccines.

21 January 2018

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Long-lasting antitumor protection by anti-CD20 antibody through cellular immune response

21 January 2018

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Rituximab immunotherapy results in the induction of a lymphoma idiotype-specific T-cell response in patients with follicular lymphoma: support for a "vaccinal effect" of rituximab

21 January 2018

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Passive immunotherapy in simian immunodeficiency virus-infected macaques accelerates the development of neutralizing antibodies

21 January 2018

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Passive neutralizing antibody controls SHIV viremia and enhances B cell responses in infant macaques.

21 January 2018

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The function of Fcγ receptors in dendritic cells and macrophages

21 January 2018

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Fcgamma receptor-mediated induction of dendritic cell maturation and major histocompatibility complex class I-restricted antigen presentation after immune complex internalization

21 January 2018

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Inducing tumor immunity through the selective engagement of activating Fcgamma receptors on dendritic cells

21 January 2018

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IgG2a-mediated enhancement of antibody responses is dependent on FcRgamma+ bone marrow-derived cells.

21 January 2018

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Selective blockade of inhibitory Fcgamma receptor enables human dendritic cell maturation with IL-12p70 production and immunity to antibody-coated tumor cells

21 January 2018

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Sialylation levels of anti-proteinase 3 antibodies are associated with the activity of granulomatosis with polyangiitis (Wegener's)

21 January 2018

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A 13-amino-acid motif in the cytoplasmic domain of FcγRIIB modulates B-cell receptor signalling

21 January 2018

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The high affinity Fc gamma receptor (CD64) induces phagocytosis in the absence of its cytoplasmic domain: the gamma subunit of Fc gamma RIIIA imparts phagocytic function to Fc gamma RI

21 January 2018

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12 December 2020

SHIP recruitment attenuates Fc gamma RIIB-induced B cell apoptosis

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12 December 2020

Fc gamma RIIIA-mediated signaling involves src-family lck in human natural killer cells.

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12 December 2020

FcγRIIb controls bone marrow plasma cell persistence and apoptosis

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12 December 2020

Increased expression of FcgammaRI/CD64 on circulating monocytes parallels ongoing inflammation and nephritis in lupus

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12 December 2020

Regulation of B cell functions by the sialic acid-binding receptors siglec-G and CD22.

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12 December 2020

Phosphatidylinositol 3-kinase and ERK are required for NF-kappaB activation but not for phagocytosis

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12 December 2020

Involvement of phosphatidylinositol 3-kinase in Fc gamma receptor signaling.

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12 December 2020

Clustering of the high affinity Fc receptor for immunoglobulin G (Fc gamma RI) results in phosphorylation of its associated gamma-chain

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12 December 2020

Therapeutic activity of humanized anti-CD20 monoclonal antibody and polymorphism in IgG Fc receptor FcgammaRIIIa gene

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12 December 2020

Therapeutic efficacy of potent neutralizing HIV-1-specific monoclonal antibodies in SHIV-infected rhesus monkeys

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12 December 2020

Application of the immune complex for immune protection against viral disease

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12 December 2020

Abnormal glycosylation of serum igg from patients with chronic inflammatory diseases

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12 December 2020

The Fc gamma RI receptor signals through the activation of hck and MAP kinase

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12 December 2020

Molecular characterization of six variant Fcgamma receptor class I (CD64) transcripts

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12 December 2020

DC-SIGN (dendritic cell-specific ICAM-grabbing non-integrin) and DC-SIGN-related (DC-SIGNR): friend or foe?

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12 December 2020

IFN-γ induces the high-affinity Fc receptor I for IgG (CD64) on human glomerular mesangial cells

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12 December 2020

Basis of the intrinsic flexibility of the Cε3 domain of IgE

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12 December 2020

Changes in antigen-specific IgG1 Fc N-glycosylation upon influenza and tetanus vaccination

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12 December 2020

Modulation of Fc gamma and complement receptor function by the glycosyl-phosphatidylinositol-anchored form of Fc gamma RIII

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12 December 2020

Protein-tyrosine kinase p72syk in Fc gamma RI receptor signaling

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12 December 2020

Differential control of the tyrosine kinases Lyn and Syk by the two signaling chains of the high affinity immunoglobulin E receptor

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12 December 2020

Passive immunization against Cryptococcus neoformans with an isotype-switch family of monoclonal antibodies reactive with cryptococcal polysaccharide

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12 December 2020

Immune complexes as immunizing agents to increase the number of monoclonal antibody producing hybrids and to deviate the response to poorly immunogenic epitopes

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12 December 2020

Antibody-mediated immunotherapy of macaques chronically infected with SHIV suppresses viraemia

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12 December 2020

Spontaneous autoimmune disease in Fc(gamma)RIIB-deficient mice results from strain-specific epistasis

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12 December 2020

Opsonization of Cryptococcus neoformans by a family of isotype-switch variant antibodies specific for the capsular polysaccharide

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12 December 2020

Efficacy of a novel infectious bursal disease virus immune complex vaccine in broiler chickens.

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12 December 2020

Fc gamma receptor IIB on dendritic cells enforces peripheral tolerance by inhibiting effector T cell responses

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12 December 2020

Sweet and sour: the role of glycosylation for the anti-inflammatory activity of immunoglobulin G.

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12 December 2020

Expression of functional CD32 molecules on human NK cells is determined by an allelic polymorphism of the FcgammaRIIC gene.

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12 December 2020

Three genes for the human high affinity Fc receptor for IgG (Fc gamma RI) encode four distinct transcription products

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12 December 2020

Natural killer cell and granulocyte Fc gamma receptor III (CD16) differ in membrane anchor and signal transduction

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12 December 2020

Analysis of signal transduction pathways regulating cytokine-mediated Fc receptor activation on human eosinophils

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12 December 2020

Identifiers

DOI

10.1111/IMR.12343

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4 September 2017

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PubMed ID

26497515