The Significance and Therapeutic Potential of GATA3 Expression and Mutation in Breast Cancer: A Systematic Review (Q38574882)

4 September 2017

The Significance and Therapeutic Potential of GATA3 Expression and Mutation in Breast Cancer: A Systematic Review (English)

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4 September 2017

Feng Du

1

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4 September 2017

Peng Yuan

2

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4 September 2017

Teng Wang

3

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4 September 2017

Jiuda Zhao

4

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4 September 2017

Zitong Zhao

5

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4 September 2017

Yang Luo

6

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4 September 2017

Binghe Xu

7

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4 September 2017

language of work or name

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27 August 2015

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Medicinal Research Reviews

4 September 2017

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4 September 2017

35

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4 September 2017

6

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4 September 2017

1300-1315

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Friend of GATA-1 represses GATA-3-dependent activity in CD4+ T cells.

4 September 2017

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Essential role of GATA3 for the maintenance of type 2 helper T (Th2) cytokine production and chromatin remodeling at the Th2 cytokine gene loci

21 January 2018

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GATA3 in development and cancer differentiation: cells GATA have it!

21 January 2018

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GATA-3 regulates the self-renewal of long-term hematopoietic stem cells

21 January 2018

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Critical role of p38 and GATA3 in natural helper cell function

21 January 2018

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GATA-3 function in innate and adaptive immunity.

21 January 2018

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GATA-3: an unexpected regulator of cell lineage determination in skin

21 January 2018

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GATA-3 maintains the differentiation of the luminal cell fate in the mammary gland

21 January 2018

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Gata3 acts downstream of beta-catenin signaling to prevent ectopic metanephric kidney induction

21 January 2018

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T helper cell differentiation: on again, off again

21 January 2018

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TH1/TH2 cell differentiation and molecular signals

21 January 2018

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T-bet and GATA3 orchestrate Th1 and Th2 differentiation through lineage-specific targeting of distal regulatory elements.

21 January 2018

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Transcription factor interplay in T helper cell differentiation

21 January 2018

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Transcription factor GATA-3 is differentially expressed in murine Th1 and Th2 cells and controls Th2-specific expression of the interleukin-5 gene

21 January 2018

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Targeted disruption of the GATA3 gene causes severe abnormalities in the nervous system and in fetal liver haematopoiesis

21 January 2018

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GATA3 haplo-insufficiency causes human HDR syndrome

21 January 2018

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Characterization of GATA3 mutations in the hypoparathyroidism, deafness, and renal dysplasia (HDR) syndrome

21 January 2018

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Gata-3 is an essential regulator of mammary-gland morphogenesis and luminal-cell differentiation

21 January 2018

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Function of GATA transcription factors in preadipocyte-adipocyte transition

21 January 2018

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Ki-67 as prognostic marker in early breast cancer: a meta-analysis of published studies involving 12,155 patients

21 January 2018

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Ki67 in breast cancer: prognostic and predictive potential

21 January 2018

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Ki67 levels as predictive and prognostic parameters in pretherapeutic breast cancer core biopsies: a translational investigation in the neoadjuvant GeparTrio trial.

21 January 2018

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GATA-3 links tumor differentiation and dissemination in a luminal breast cancer model

21 January 2018

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Genes that mediate breast cancer metastasis to lung

21 January 2018

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GATA3 inhibits breast cancer growth and pulmonary breast cancer metastasis

21 January 2018

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Epithelial-mesenchymal transitions in tumour progression

21 January 2018

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Transduction of a mesenchyme-specific gene periostin into 293T cells induces cell invasive activity through epithelial-mesenchymal transformation

21 January 2018

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Ras and TGF[beta] cooperatively regulate epithelial cell plasticity and metastasis: dissection of Ras signaling pathways

21 January 2018

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GATA3 inhibits breast cancer metastasis through the reversal of epithelial-mesenchymal transition

21 January 2018

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Gata-3 negatively regulates the tumor-initiating capacity of mammary luminal progenitor cells and targets the putative tumor suppressor caspase-14.

21 January 2018

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GATA3 cooperates with PARP1 to regulate CCND1 transcription through modulating histone H1 incorporation

21 January 2018

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Inhibition of Bax channel-forming activity by Bcl-2

21 January 2018

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The Dachshund gene in development and hormone-responsive tumorigenesis

21 January 2018

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Cell fate determination factor Dachshund reprograms breast cancer stem cell function

21 January 2018

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DACH1 regulates cell cycle progression of myeloid cells through the control of cyclin D, Cdk 4/6 and p21Cip1.

21 January 2018

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ADAMTSL-6 is a novel extracellular matrix protein that binds to fibrillin-1 and promotes fibrillin-1 fibril formation

21 January 2018

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Shift in GATA3 functions, and GATA3 mutations, control progression and clinical presentation in breast cancer

21 January 2018

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Expression of cytokeratins 17 and 5 identifies a group of breast carcinomas with poor clinical outcome

21 January 2018

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Identification of GATA3 as a breast cancer prognostic marker by global gene expression meta-analysis

21 January 2018

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GATA-3 expression in breast cancer has a strong association with estrogen receptor but lacks independent prognostic value

21 January 2018

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Classification of breast cancer using genetic algorithms and tissue microarrays

21 January 2018

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Generation of a functional mammary gland from a single stem cell

21 January 2018

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Transcriptome analysis of mammary epithelial subpopulations identifies novel determinants of lineage commitment and cell fate

21 January 2018

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Spatial and temporal expression of the Cre gene under the control of the MMTV-LTR in different lines of transgenic mice.

21 January 2018

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Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers

21 January 2018

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Detection and analysis of mammary gland stem cells

21 January 2018

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Molecular portraits of human breast tumours

21 January 2018

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Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications

21 January 2018

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Repeated observation of breast tumor subtypes in independent gene expression data sets

21 January 2018

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Gene expression profiles of primary breast tumors maintained in distant metastases

21 January 2018

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Progesterone receptor activation downregulates GATA3 by transcriptional repression and increased protein turnover promoting breast tumor growth

21 January 2018

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Prognosis of hormone-dependent breast cancers: implications of the presence of dysfunctional transcriptional networks activated by insulin via the immune transcription factor T-bet

21 January 2018

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Predicting the clinical status of human breast cancer by using gene expression profiles

21 January 2018

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Gene expression profiling predicts clinical outcome of breast cancer

21 January 2018

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About GATA3, HNF3A, and XBP1, three genes co-expressed with the oestrogen receptor-alpha gene (ESR1) in breast cancer

21 January 2018

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Positive cross-regulatory loop ties GATA-3 to estrogen receptor alpha expression in breast cancer

21 January 2018

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A shared transcriptional program in early breast neoplasias despite genetic and clinical distinctions

21 January 2018

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GATA3 acts upstream of FOXA1 in mediating ESR1 binding by shaping enhancer accessibility

21 January 2018

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Structure and expression of the human GATA3 gene

21 January 2018

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Human GATA-3 trans-activation, DNA-binding, and nuclear localization activities are organized into distinct structural domains

21 January 2018

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Frequent somatic mutations of GATA3 in non-BRCA1/BRCA2 familial breast tumors, but not in BRCA1-, BRCA2- or sporadic breast tumors.

21 January 2018

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GATA3 mutations define a unique subtype of luminal-like breast cancer with improved survival.

21 January 2018

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Somatic sequence alterations in twenty-one genes selected by expression profile analysis of breast carcinomas

21 January 2018

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Sequence analysis of mutations and translocations across breast cancer subtypes

21 January 2018

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Clinicopathological analysis of GATA3-positive breast cancers with special reference to response to neoadjuvant chemotherapy.

21 January 2018

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GATA3 mutations found in breast cancers may be associated with aberrant nuclear localization, reduced transactivation and cell invasiveness

21 January 2018

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Transcriptional cofactors of the FOG family interact with GATA proteins by means of multiple zinc fingers

21 January 2018

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Mutation of GATA3 in human breast tumors

21 January 2018

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Breast tumor specific mutation in GATA3 affects physiological mechanisms regulating transcription factor turnover

21 January 2018

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Crystal Structures of Multiple GATA Zinc Fingers Bound to DNA Reveal New Insights into DNA Recognition and Self-Association by GATA

21 January 2018

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Functional characterization of GATA3 mutations causing the hypoparathyroidism-deafness-renal (HDR) dysplasia syndrome: insight into mechanisms of DNA binding by the GATA3 transcription factor.

21 January 2018

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A missense GATA3 mutation, Thr272Ile, causes the hypoparathyroidism, deafness, and renal dysplasia syndrome

21 January 2018

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Analysis of the signals and mechanisms mediating nuclear trafficking of GATA-4. Loss of DNA binding is associated with localization in intranuclear speckles

21 January 2018

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Associations between gene expressions in breast cancer and patient survival

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/MED.21362

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4 September 2017

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