Inosine 5'-monophosphate dehydrogenase inhibitors as antimicrobial agents: recent progress and future perspectives. (Q38558374)

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20 February 2020

review article

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title

Inosine 5'-monophosphate dehydrogenase inhibitors as antimicrobial agents: recent progress and future perspectives (English)

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20 February 2020

1

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20 February 2020

Prashant S Kharkar

series ordinal

2

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20 February 2020

author name string

Chetan P Shah

series ordinal

1

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4 September 2017

Prashant S Kharkar

series ordinal

2

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4 September 2017

publication date

1 January 2015

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Future Medicinal Chemistry

20 February 2020

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26230881%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

volume

7

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issue

11

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20 February 2020

page(s)

1415-1429

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Appropriate antimicrobial therapy in the era of multidrug-resistant human pathogens

20 February 2020

cites work

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Anthrax: A disease of biowarfare and public health importance

21 January 2018

1 reference

Novel approaches are needed to develop tomorrow's antibacterial therapies

21 January 2018

1 reference

Enteric protozoa in the developed world: a public health perspective.

21 January 2018

1 reference

Targeting a prokaryotic protein in a eukaryotic pathogen: identification of lead compounds against cryptosporidiosis

21 January 2018

1 reference

Counteracting antibiotic resistance: breaking barriers among antibacterial strategies

21 January 2018

1 reference

From crystal to compound: structure-based antimalarial drug discovery

21 January 2018

1 reference

Repurposing cryptosporidium inosine 5'-monophosphate dehydrogenase inhibitors as potential antibacterial agents.

21 January 2018

1 reference

IMP dehydrogenase: structure, mechanism, and inhibition

21 January 2018

1 reference

Validation of IMP dehydrogenase inhibitors in a mouse model of cryptosporidiosis

21 January 2018

1 reference

Novel inhibitors of inosine monophosphate dehydrogenase in patent literature of the last decade

21 January 2018

1 reference

A novel cofactor-binding mode in bacterial IMP dehydrogenases explains inhibitor selectivity

21 January 2018

1 reference

The antibiotic potential of prokaryotic IMP dehydrogenase inhibitors

21 January 2018

1 reference

Inosine monophosphate dehydrogenase as a target for antiviral, anticancer, antimicrobial and immunosuppressive therapeutics

21 January 2018

1 reference

Gene transfer in the evolution of parasite nucleotide biosynthesis

21 January 2018

1 reference

Triazole-linked inhibitors of inosine monophosphate dehydrogenase from human and Mycobacterium tuberculosis

21 January 2018

1 reference

Optimization of Benzoxazole-Based Inhibitors of Cryptosporidium parvum Inosine 5′-Monophosphate Dehydrogenase

21 January 2018

1 reference

A screening pipeline for antiparasitic agents targeting cryptosporidium inosine monophosphate dehydrogenase

21 January 2018

1 reference

Triazole inhibitors of Cryptosporidium parvum inosine 5'-monophosphate dehydrogenase

21 January 2018

1 reference

Structure-activity relationship study of selective benzimidazole-based inhibitors of Cryptosporidium parvum IMPDH.

21 January 2018

1 reference

Phthalazinone inhibitors of inosine-5'-monophosphate dehydrogenase from Cryptosporidium parvum.

21 January 2018

1 reference

Selective and potent urea inhibitors of cryptosporidium parvum inosine 5'-monophosphate dehydrogenase

21 January 2018

1 reference

The Structural Basis of Cryptosporidium-Specific IMP Dehydrogenase Inhibitor Selectivity

21 January 2018

1 reference

Structural determinants of inhibitor selectivity in prokaryotic IMP dehydrogenases

21 January 2018

1 reference

Bacillus anthracis Inosine 5′-Monophosphate Dehydrogenase in Action: The First Bacterial Series of Structures of Phosphate Ion-, Substrate-, and Product-Bound Complexes

21 January 2018

1 reference

A heterocyclic molecule with significant activity against dengue virus

21 January 2018

1 reference

Inhibition of dengue virus replication by mycophenolic acid and ribavirin

21 January 2018

1 reference

Inhibitory effect of curcumin on IMP dehydrogenase, the target for anticancer and antiviral chemotherapy agents

21 January 2018

1 reference

Identification of novel diphenyl urea inhibitors of Mt-GuaB2 active against Mycobacterium tuberculosis

21 January 2018

1 reference

Synthesis and antiviral activity of a novel class of (5-oxazolyl)phenyl amines

21 January 2018

1 reference

Synthesis, in vitro evaluation and cocrystal structure of 4-oxo-[1]benzopyrano[4,3-c]pyrazole Cryptosporidium parvum inosine 5'-monophosphate dehydrogenase (CpIMPDH) inhibitors

21 January 2018

1 reference

Mycophenolic Acid: a one hundred year odyssey from antibiotic to immunosuppressant

21 January 2018

1 reference

The effect of mycophenolic acid on the growth of Staphylococcus aureus in heart broth

21 January 2018

1 reference

The effect of mycophenolic acid on the cell cycle of Candida albicans

21 January 2018

1 reference

Cellular IMPDH enzyme activity is a potential target for the inhibition of Chikungunya virus replication and virus induced apoptosis in cultured mammalian cells

21 January 2018

1 reference

Identification of novel Mt-Guab2 inhibitor series active against M. tuberculosis

21 January 2018

1 reference

Virtual and experimental high-throughput screening (HTS) in search of novel inosine 5'-monophosphate dehydrogenase II (IMPDH II) inhibitors

21 January 2018

1 reference

Design, synthesis and biological evaluation of novel inosine 5'-monophosphate dehydrogenase (IMPDH) inhibitors.

21 January 2018

1 reference

Two classes of bacterial IMPDHs according to their quaternary structures and catalytic properties

21 January 2018

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The CBS domain: a protein module with an emerging prominent role in regulation

21 January 2018

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CBS domains: Ligand binding sites and conformational variability.

21 January 2018

1 reference

CBS domains: structure, function, and pathology in human proteins

21 January 2018

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The structure of a domain common to archaebacteria and the homocystinuria disease protein

21 January 2018

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MgATP regulates allostery and fiber formation in IMPDHs

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.4155/FMC.15.72

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26230881%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

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