The p53 tumour suppressor gene (Q38548852)

4 September 2017

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title

The p53 tumour suppressor gene (English)

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4 September 2017

Steele RJ

1

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4 September 2017

Thompson AM

series ordinal

2

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4 September 2017

Hall PA

series ordinal

3

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4 September 2017

Lane DP

series ordinal

4

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4 September 2017

language of work or name

English

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publication date

1 November 1998

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British Journal of Surgery

4 September 2017

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4 September 2017

85

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4 September 2017

11

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4 September 2017

1460-1467

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https://api.crossref.org/works/10.1046%2FJ.1365-2168.1998.00910.X

4 September 2017

1 reference

Nucleotide sequences related to the transforming gene of avian sarcoma virus are present in DNA of uninfected vertebrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2168.1998.00910.X

A mutation in the RET proto-oncogene associated with multiple endocrine neoplasia type 2B and sporadic medullary thyroid carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2168.1998.00910.X

T antigen is bound to a host protein in SY40-transformed cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2168.1998.00910.X

Characterization of a 54K Dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2168.1998.00910.X

p53, the cellular gatekeeper for growth and division

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2168.1998.00910.X

High-frequency developmental abnormalities in p53-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2168.1998.00910.X

A teratologic suppressor role for p53 in benzo[a]pyrene-treated transgenic p53-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2168.1998.00910.X

Tumor suppressors: a developing role for p53?

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2168.1998.00910.X

DNA damage induces phosphorylation of the amino terminus of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2168.1998.00910.X

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2168.1998.00910.X

Mdm2 promotes the rapid degradation of p53

21 January 2018

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https://api.crossref.org/works/10.1046%2FJ.1365-2168.1998.00910.X

Regulation of p53 stability by Mdm2

21 January 2018

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https://api.crossref.org/works/10.1046%2FJ.1365-2168.1998.00910.X

The p53-mdm-2 autoregulatory feedback loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2168.1998.00910.X

Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2168.1998.00910.X

MDM2--arbiter of p53's destruction

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2168.1998.00910.X

Induction of Mdm2 and enhancement of cell survival by bFGF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2168.1998.00910.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2168.1998.00910.X

p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2168.1998.00910.X

Induction of apoptosis in HeLa cells by trans-activation-deficient p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2168.1998.00910.X

A novel protein with strong homology to the tumor suppressor p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2168.1998.00910.X

p73 is a simian [correction of human] p53-related protein that can induce apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2168.1998.00910.X

Identification of RB18A, a 205 kDa new p53 regulatory protein which shares antigenic and functional properties with p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2168.1998.00910.X

p53CP, a putative p53 competing protein that specifically binds to the consensus p53 DNA binding sites: a third member of the p53 family?

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2168.1998.00910.X

Oncogenic forms of p53 inhibit p53-regulated gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2168.1998.00910.X

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2168.1998.00910.X

Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2168.1998.00910.X

Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2168.1998.00910.X

The multistep nature of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2168.1998.00910.X

p53 protein stability in tumour cells is not determined by mutation but is dependent on Mdm2 binding.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2168.1998.00910.X

Accumulation of p53 Tumor Suppressor Gene Protein: An Independent Marker of Prognosis in Breast Cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2168.1998.00910.X

Increased p53 protein content of colorectal tumours correlates with poor survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2168.1998.00910.X

Cytoplasmic accumulation of p53 protein: an independent prognostic indicator in colorectal adenocarcinomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2168.1998.00910.X

p53 and Rb1 protein expression: are they prognostically useful in colorectal cancer?

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2168.1998.00910.X

An evaluation of six antibodies for immunohistochemistry of mutant p53 gene product in archival colorectal neoplasms

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2168.1998.00910.X

The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2168.1998.00910.X

A mutant p53 that discriminates between p53-responsive genes cannot induce apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2168.1998.00910.X

Amplification of a gene encoding a p53-associated protein in human sarcomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2168.1998.00910.X

The candidate tumour suppressor p33ING1 cooperates with p53 in cell growth control

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2168.1998.00910.X

p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2168.1998.00910.X

p53 mutations increase resistance to ionizing radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2168.1998.00910.X

The human papilloma virus 16E6 gene sensitizes human mammary epithelial cells to apoptosis induced by DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2168.1998.00910.X

Novel combination therapy for human colon cancer with adenovirus-mediated wild-type p53 gene transfer and DNA-damaging chemotherapeutic agent

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2168.1998.00910.X

Retrovirus-mediated wild-type p53 gene transfer to tumors of patients with lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2168.1998.00910.X

An adenovirus mutant that replicates selectively in p53-deficient human tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2168.1998.00910.X

ONYX-015, an E1B gene-attenuated adenovirus, causes tumor-specific cytolysis and antitumoral efficacy that can be augmented by standard chemotherapeutic agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2168.1998.00910.X

Regulation of the cryptic sequence-specific DNA-binding function of p53 by protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2168.1998.00910.X

Regulation of the sequence-specific DNA binding function of p53 by protein kinase C and protein phosphatases

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2168.1998.00910.X

Small peptides activate the latent sequence-specific DNA binding function of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2168.1998.00910.X

p53 expression and prognosis in gastric carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2168.1998.00910.X

Increased expression of mutant forms of p53 oncogene in primary lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2168.1998.00910.X

Mutations of the p53 Gene as a Predictor of Poor Prognosis in Patients With Non-Small-Cell Lung Cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2168.1998.00910.X

Sunburn and p53 in the onset of skin cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2168.1998.00910.X

10.1046/J.1365-2168.1998.00910.X

21 January 2018

Identifiers

DOI

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4 September 2017

1 reference