Toxicological and pathological applications of proliferating cell nuclear antigen (PCNA), a novel endogenous marker for cell proliferation (Q38486723)

3 September 2017

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title

Toxicological and pathological applications of proliferating cell nuclear antigen (PCNA), a novel endogenous marker for cell proliferation (English)

1 reference

3 September 2017

Dietrich DR

1

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PubMed ID

8097093

3 September 2017

language of work or name

English

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publication date

1 January 1993

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Critical Reviews in Toxicology

3 September 2017

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3 September 2017

23

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3 September 2017

77-109

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3 September 2017

1

1 reference

Cloning and sequence of the human nuclear protein cyclin: homology with DNA-binding proteins

3 September 2017

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Involvement of proliferating cell nuclear antigen (cyclin) in DNA replication in living cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Quantitation and subcellular localization of proliferating cell nuclear antigen (PCNA/cyclin) in oocytes and eggs of Xenopus laevis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Cyclin (PCNA, auxiliary protein of DNA polymerase delta) is a central component of the pathway(s) leading to DNA replication and cell division

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Drosophila proliferating cell nuclear antigen (cyclin) gene: structure, expression during development, and specific binding of homeodomain proteins to its 5'-flanking region

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Proliferating cell nuclear antigen/cyclin in the ciliate Euplotes eurystomus: localization in the replication band and in micronuclei

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Gene for proliferating-cell nuclear antigen (DNA polymerase delta auxiliary protein) is present in both mammalian and higher plant genomes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

The yeast analog of mammalian cyclin/proliferating-cell nuclear antigen interacts with mammalian DNA polymerase delta

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Viral proliferating cell nuclear antigen.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Evolutionary change in 5S RNA secondary structure and a phylogenic tree of 54 5S RNA species

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

On Some Principles Governing Molecular Evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Molecular cloning and structural analysis of mouse gene and pseudogenes for proliferating cell nuclear antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Upstream sequences of rice proliferating cell nuclear antigen (PCNA) gene mediate expression of PCNA-GUS chimeric gene in meristems of transgenic tobacco plants

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

The sequence specificity of homeodomain-DNA interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

A multigene family encoding several "finger" structures is present and differentially active in mammalian genomes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Importance of introns in the growth regulation of mRNA levels of the proliferating cell nuclear antigen gene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Characterization of proliferating cell nuclear antigen recognized by autoantibodies in lupus sera

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Sequence of a Drosophila segmentation gene: protein structure homology with DNA-binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Cyclin: a nuclear protein whose level correlates directly with the proliferative state of normal as well as transformed cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

The cell-cycle regulated proliferating cell nuclear antigen is required for SV40 DNA replication in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Molecular cloning, structure and expression of the yeast proliferating cell nuclear antigen gene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Existence of two populations of cyclin/proliferating cell nuclear antigen during the cell cycle: association with DNA replication sites

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Expression of the transformation-sensitive protein "cyclin" in normal human epidermal basal cells and simian virus 40-transformed keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Cell cycle-dependent variations in the distribution of the nuclear protein cyclin proliferating cell nuclear antigen in cultured cells: subdivision of S phase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Increased nuclear cyclin/PCNA antigen staining of non S-phase transformed human amnion cells engaged in nucleotide excision DNA repair

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Expression of proliferating cell nuclear antigen (PCNA)/cyclin during the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Proliferating cell nuclear antigen (PCNA) immunolocalization in paraffin sections: an index of cell proliferation with evidence of deregulated expression in some neoplasms.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

PCNA/cyclin expression and BrdU uptake define different subpopulations in different cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Transcriptional and posttranscriptional regulation of the proliferating cell nuclear antigen gene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Cyclin/PCNA is the auxiliary protein of DNA polymerase-delta

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Functional identity of proliferating cell nuclear antigen and a DNA polymerase-delta auxiliary protein

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Mammalian DNA polymerases alpha and delta: current status in DNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Initiation of eukaryotic DNA replication in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Coordinated leading and lagging strand synthesis during SV40 DNA replication in vitro requires PCNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Changes in cyclin/proliferating cell nuclear antigen distribution during DNA repair synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Proliferating cell nuclear antigen is required for DNA excision repair

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

A role for the human single-stranded DNA binding protein HSSB/RPA in an early stage of nucleotide excision repair

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

The p53 proto-oncogene can act as a suppressor of transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Negative growth regulation in a glioblastoma tumor cell line that conditionally expresses human wild-type p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

The p53 tumour suppressor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

The retinoblastoma protein is phosphorylated during specific phases of the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Phosphorylation of the retinoblastoma gene product is modulated during the cell cycle and cellular differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Human p53 is phosphorylated by p60-cdc2 and cyclin B-cdc2

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

The recruitment of crystallins: new functions precede gene duplication.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Presence of a potent transcription activating sequence in the p53 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Transcriptional activation by wild-type but not transforming mutants of the p53 anti-oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

The retinoblastoma susceptibility gene encodes a nuclear phosphoprotein associated with DNA binding activity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Growth suppression induced by wild-type p53 protein is accompanied by selective down-regulation of proliferating-cell nuclear antigen expression

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

T antigen is bound to a host protein in SY40-transformed cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Transforming growth factor beta 1 suppression of c-myc gene transcription: role in inhibition of keratinocyte proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

TGF-beta 1 inhibition of c-myc transcription and growth in keratinocytes is abrogated by viral transforming proteins with pRB binding domains.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Human tumor suppressor genes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Sequences in E1A proteins of human adenovirus 5 required for cell transformation, repression of a transcriptional enhancer, and induction of proliferating cell nuclear antigen.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Herpesvirus saimiri encodes homologues of G protein-coupled receptors and cyclins

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

The clam embryo protein cyclin A induces entry into M phase and the resumption of meiosis in Xenopus oocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Unraveling of mitotic control mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Cyclin: a protein specified by maternal mRNA in sea urchin eggs that is destroyed at each cleavage division

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Dominoes and clocks: the union of two views of the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Isolation of a human cyclin cDNA: evidence for cyclin mRNA and protein regulation in the cell cycle and for interaction with p34cdc2

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Cyclin a is required for the onset of DNA replication in mammalian fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

A cyclin A-protein kinase complex possesses sequence-specific DNA binding activity: p33cdk2 is a component of the E2F-cyclin A complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Nature's chemicals and synthetic chemicals: comparative toxicology

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Two-event model for carcinogenesis: biological, mathematical, and statistical considerations

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Cell proliferation in carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Preneoplastic lesions in rodent kidney induced spontaneously or by non-genotoxic agents: predictive nature and comparison to lesions induced by genotoxic carcinogens

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

A nuclear antigen associated with cell proliferation and blast transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

An enhancement method for immunohistochemical staining of proliferating cell nuclear antigen in archival rodent tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Proliferating cell nuclear antigen (PCNA/cyclin) immunocytochemistry as a labeling index in mouse lung tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Determination of proliferating fractions in malignant melanomas by anti-PCNA/cyclin monoclonal antibody

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Antigen retrieval in formalin-fixed, paraffin-embedded tissues: an enhancement method for immunohistochemical staining based on microwave oven heating of tissue sections

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Review: assessment of cell proliferation in histological material

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Method for analysis of cellular DNA content of paraffin-embedded pathological material using flow cytometry

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Flow cytometry using paraffin-embedded tissue: five years on.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

A Detergent-trypsin method for the preparation of nuclei for flow cytometric DNA analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Prognostic value of proliferating cell nuclear antigen in gastric carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

A comparison of immunohistochemical markers of cell proliferation with experimentally determined growth fraction.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Proliferating cell nuclear antigen and Ki-67 immunohistochemistry in brain tumors: A comparative study

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Cell kinetic analyses and expression of carcinoembryonic antigen, carbohydrate antigen 19-9 and DU-PAN-2 in hyperplastic, pre-neoplastic and neoplastic lesions of intrahepatic bile ducts in livers with hepatoliths

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Chromosomal localization of the human proliferating cell nuclear antigen (PCNA) gene to or close to 20p12 by in situ hybridization

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Human gene for proliferating cell nuclear antigen has pseudogenes and localizes to chromosome 20

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Highly conserved structure of proliferating cell nuclear antigen (DNA polymerase delta auxiliary protein) gene in plants

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Molecular cloning of the gene for plant proliferating-cell nuclear antigen and expression of this gene during the cell cycle in synchronized cultures of Catharanthus roseus cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Human nucleotide excision nuclease removes thymine dimers from DNA by incising the 22nd phosphodiester bond 5' and the 6th phosphodiester bond 3' to the photodimer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

In vitro phosphorylation of the tumor suppressor gene RB protein by mitosis-specific histone H1 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Wild-type p53 can inhibit oncogene-mediated focus formation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Identification of a nuclear and of a cytoplasmic polypeptide whose relative proportions are sensitive to changes in the rate of cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

Identity of the proliferating cell nuclear antigen and cyclin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449309104075

10.3109/10408449309104075

21 January 2018

Identifiers

DOI

1 reference

3 September 2017

1 reference

PubMed ID

8097093