Heat shock protein 90: a pathophysiological factor and novel treatment target in autoimmune bullous skin diseases (Q38484421)

3 September 2017

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title

Heat shock protein 90: a pathophysiological factor and novel treatment target in autoimmune bullous skin diseases (English)

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3 September 2017

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2

Detlef Zillikens

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3 September 2017

Stefan Tukaj

1

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PubMed ID

25980533

3 September 2017

Michael Kasperkiewicz

series ordinal

3

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3 September 2017

3 June 2015

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3 September 2017

Experimental Dermatology

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3 September 2017

24

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3 September 2017

8

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3 September 2017

567-571

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HSP90 at the hub of protein homeostasis: emerging mechanistic insights

3 September 2017

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Functional proteomic screens reveal an essential extracellular role for hsp90 alpha in cancer cell invasiveness

21 January 2018

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Inhibition of HSP90 molecular chaperones: moving into the clinic

21 January 2018

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Roles of heat-shock proteins in innate and adaptive immunity

21 January 2018

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Granulocyte-derived elastase and gelatinase B are required for dermal-epidermal separation induced by autoantibodies from patients with epidermolysis bullosa acquisita and bullous pemphigoid

21 January 2018

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The pathophysiology of bullous pemphigoid

21 January 2018

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Small molecule inhibitors of Hsp90 potently affect inflammatory disease pathways and exhibit activity in models of rheumatoid arthritis

21 January 2018

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EC144, a synthetic inhibitor of heat shock protein 90, blocks innate and adaptive immune responses in models of inflammation and autoimmunity

21 January 2018

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Identification of gp96 as a novel target for treatment of autoimmune disease in mice

21 January 2018

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Heat shock protein 90 inhibition by 17-DMAG lessens disease in the MRL/lpr mouse model of systemic lupus erythematosus

21 January 2018

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Heat shock protein 90 is required for ex vivo neutrophil-driven autoantibody-induced tissue damage in experimental epidermolysis bullosa acquisita

21 January 2018

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Aberrant expression and secretion of heat shock protein 90 in patients with bullous pemphigoid

21 January 2018

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Hsp90 blockade modulates bullous pemphigoid IgG-induced IL-8 production by keratinocytes

21 January 2018

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Evidence for a role of autoantibodies to heat shock protein 60, 70, and 90 in patients with dermatitis herpetiformis.

21 January 2018

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Clinical presentation, pathogenesis, diagnosis, and treatment of epidermolysis bullosa acquisita

21 January 2018

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Inhibitory effects of heat shock protein 90 blockade on proinflammatory human Th1 and Th17 cell subpopulations

21 January 2018

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Histone deacetylase 6 and heat shock protein 90 control the functions of Foxp3(+) T-regulatory cells

21 January 2018

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Inhibition of N-terminal ATPase on HSP90 attenuates colitis through enhanced Treg function.

21 January 2018

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Autoantibodies to type VII collagen mediate Fcgamma-dependent neutrophil activation and induce dermal-epidermal separation in cryosections of human skin

21 January 2018

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Hsp90 regulates NADPH oxidase activity and is necessary for superoxide but not hydrogen peroxide production

21 January 2018

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Opposing actions of heat shock protein 90 and 70 regulate nicotinamide adenine dinucleotide phosphate oxidase stability and reactive oxygen species production.

21 January 2018

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GM-CSF modulates autoantibody production and skin blistering in experimental epidermolysis bullosa acquisita

21 January 2018

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Collagen XVII (BP180) modulates keratinocyte expression of the proinflammatory chemokine, IL-8

21 January 2018

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Do reciprocal interactions between cell stress proteins and cytokines create a new intra-/extra-cellular signalling nexus?

21 January 2018

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21 January 2018

Dermatitis herpetiformis

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Circulating antibodies to heat-shock protein 60 in Crohn's disease and ulcerative colitis

21 January 2018

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The involvement of heat-shock proteins in the pathogenesis of autoimmune arthritis: a critical appraisal

21 January 2018

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Hsp40 proteins modulate humoral and cellular immune response in rheumatoid arthritis patients.

21 January 2018

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Heat shock protein 60 and immune inflammatory responses in atherosclerosis

21 January 2018

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HLA-linked heat-shock protein 70 (HSP70-2) gene polymorphism and celiac disease

21 January 2018

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In celiac disease, a subset of autoantibodies against transglutaminase binds toll-like receptor 4 and induces activation of monocytes

21 January 2018

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Immunomodulatory effects of heat shock protein 90 inhibition on humoral immune responses

21 January 2018

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Increased Heat Shock Protein 72 Expression in Celiac Disease

21 January 2018

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21 January 2018

Identifiers

DOI

10.1111/EXD.12760

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3 September 2017

1 reference

PubMed ID

25980533