Trypanosoma brucei gamma-glutamylcysteine synthetase. Characterization of the kinetic mechanism and the role of Cys-319 in cystamine inactivation. (Q38332894)

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English	Trypanosoma brucei gamma-glutamylcysteine synthetase. Characterization of the kinetic mechanism and the role of Cys-319 in cystamine inactivation.	scientific article

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5 December 2019

Trypanosoma brucei gamma-glutamylcysteine synthetase. Characterization of the kinetic mechanism and the role of Cys-319 in cystamine inactivation (English)

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5 December 2019

Trypanosoma brucei

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Deirdre Brekken

1

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5 December 2019

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M A Phillips

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1 October 1998

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5 December 2019

Journal of Biological Chemistry

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5 December 2019

273

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41

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5 December 2019

26317-26322

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5 December 2019

Molecular mechanisms and therapeutic approaches to the treatment of African trypanosomiasis

1 reference

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Trypanothione: a novel bis(glutathionyl)spermidine cofactor for glutathione reductase in trypanosomatids

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Co-amplification of the gamma-glutamylcysteine synthetase gene gsh1 and of the ABC transporter gene pgpA in arsenite-resistant Leishmania tarentolae.

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Bovine Lenticular gamma-Glutamylcysteine Synthetase: Reaction Sequence

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Assay, purification, properties and mechanism of action of γ-glutamylcysteine synthetase from the liver of the rat and Xenopus laevis

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21 January 2018

On the active site thiol of gamma-glutamylcysteine synthetase: relationships to catalysis, inhibition, and regulation

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Characterization of Trypanosoma brucei gamma-glutamylcysteine synthetase, an essential enzyme in the biosynthesis of trypanothione (diglutathionylspermidine).

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Molecular cloning of the gamma-glutamylcysteine synthetase gene of Saccharomyces cerevisiae

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Gcs1, a gene encoding gamma-glutamylcysteine synthetase in the fission yeast Schizosaccharomyces pombe.

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Rapid and efficient site-specific mutagenesis without phenotypic selection

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