Induction of topoisomerase I cleavage complexes by the vinyl chloride adduct 1,N6-ethenoadenine (Q38332699)

2 September 2017

Induction of topoisomerase I cleavage complexes by the vinyl chloride adduct 1,N6-ethenoadenine (English)

1 reference

2 September 2017

Pourquier P

1

1 reference

2 September 2017

Bjornsti MA

series ordinal

2

1 reference

2 September 2017

Pommier Y

series ordinal

3

1 reference

2 September 2017

language of work or name

English

0 references

publication date

1 October 1998

1 reference

Journal of Biological Chemistry

2 September 2017

1 reference

2 September 2017

273

1 reference

2 September 2017

42

1 reference

2 September 2017

27245-27249

1 reference

Vinyl carbamate epoxide, a major strong electrophilic, mutagenic and carcinogenic metabolite of vinyl carbamate and ethyl carbamate (urethane).

2 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.42.27245

Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.42.27245

Mutagenic and genotoxic effects of three vinyl chloride-induced DNA lesions: 1,N6-ethenoadenine, 3,N4-ethenocytosine, and 4-amino-5-(imidazol-2-yl)imidazole.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.42.27245

The vinyl chloride DNA derivative N2,3-ethenoguanine produces G----A transitions in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.42.27245

Mechanisms of mutagenesis by the vinyl chloride metabolite chloroacetaldehyde. Effect of gene-targeted in vitro adduction of M13 DNA on DNA template activity in vivo and in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.42.27245

1,N6-ethenodeoxyadenosine, a DNA adduct highly mutagenic in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.42.27245

All four known cyclic adducts formed in DNA by the vinyl chloride metabolite chloroacetaldehyde are released by a human DNA glycosylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.42.27245

1,N6-ethenoadenine and 3,N4-ethenocytosine are excised by separate human DNA glycosylases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.42.27245

Eukaryotic DNA topoisomerases I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.42.27245

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.42.27245

Effects of uracil incorporation, DNA mismatches, and abasic sites on cleavage and religation activities of mammalian topoisomerase I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.42.27245

Apurinic sites are position-specific topoisomerase II poisons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.42.27245

Overexpression of human DNA topoisomerase I in insect cells using a baculovirus vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.42.27245

A high affinity topoisomerase I binding sequence is clustered at DNAase I hypersensitive sites in Tetrahymena R-chromatin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.42.27245

Differential stabilization of eukaryotic DNA topoisomerase I cleavable complexes by camptothecin derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.42.27245

Interaction of an alkylating camptothecin derivative with a DNA base at topoisomerase I-DNA cleavage sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.42.27245

New technique for uncoupling the cleavage and religation reactions of eukaryotic topoisomerase I. The mode of action of camptothecin at a specific recognition site

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.42.27245

Peptide sequencing and site-directed mutagenesis identify tyrosine-727 as the active site tyrosine of Saccharomyces cerevisiae DNA topoisomerase I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.42.27245

Deoxyhexanucleotide containing a vinyl chloride induced DNA lesion, 1,N6-ethenoadenine: synthesis, physical characterization, and incorporation into a duplex bacteriophage M13 genome as part of an amber codon

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.42.27245

Crystal structures of human topoisomerase I in covalent and noncovalent complexes with DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.42.27245

Molecular modeling studies of the DNA-topoisomerase I ternary cleavable complex with camptothecin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.42.27245

1,N6-ethenodeoxyadenosine and 3,N4-ethenodeoxycytine in liver DNA from humans and untreated rodents detected by immunoaffinity/32P-postlabeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.42.27245

Formation of 1,N6-ethenoadenine and 3,N4-ethenocytosine by lipid peroxidation products and nucleic acid bases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.42.27245

Mechanism of action of eukaryotic DNA topoisomerase I and drugs targeted to the enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.42.27245

Trapping of mammalian topoisomerase I and recombinations induced by damaged DNA containing nicks or gaps. Importance of DNA end phosphorylation and camptothecin effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.42.27245

Spontaneous DNA damage stimulates topoisomerase II-mediated DNA cleavage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.42.27245

Mutational Analysis of 39 Residues of Vaccinia DNA Topoisomerase Identifies Lys-220, Arg-223, and Asn-228 as Important for Covalent Catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.42.27245

Roles of the vinyl chloride oxidation products 1-chlorooxirane and 2-chloroacetaldehyde in the in vitro formation of etheno adducts of nucleic acid bases [corrected]

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.42.27245

A catalytic domain of eukaryotic DNA topoisomerase I

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.42.27245

Novel 7-alkyl methylenedioxy-camptothecin derivatives exhibit increased cytotoxicity and induce persistent cleavable complexes both with purified mammalian topoisomerase I and in human colon carcinoma SW620 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.42.27245

Misincorporation of nucleotides opposite five-membered exocyclic ring guanine derivatives by escherichia coli polymerases in vitro and in vivo: 1,N2-ethenoguanine, 5,6,7,9-tetrahydro-9-oxoimidazo[1, 2-a]purine, and 5,6,7,9-tetrahydro-7-hydroxy-9-oxo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.42.27245

21 January 2018

Identifiers

DOI

10.1074/JBC.273.42.27245

1 reference

release_j7cdhuoxovhl3euw7ljo4uksci

2 September 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/j7cdhuoxovhl3euw7ljo4uksci

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference