EPHA4 is a disease modifier of amyotrophic lateral sclerosis in animal models and in humans (Q38322311)

2 September 2017

EPHA4 is a disease modifier of amyotrophic lateral sclerosis in animal models and in humans (English)

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amyotrophic lateral sclerosis

2 September 2017

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Survival of motor neuron 1, telomeric

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GOA release 2020-03-11

author

Vincent N Thijs

13

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2 September 2017

17

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2 September 2017

Kim A Staats

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Angela R. Laird

Angela S Laird

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Ann M. Turnley

Ann M Turnley

14

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Robin Lemmens

Robin Lemmens

3

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Philip Van Damme

Philip Van Damme

20

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Ludo Van Den Bosch

Ludo Van Den Bosch

18

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Ammar Al-Chalabi

Ammar Al-Chalabi

12

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An Goris

An Goris

9

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Leonard H van den Berg

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Leonard H van den Berg

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2 September 2017

23

Wim Robberecht

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2 September 2017

11

Peter M Andersen

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2 September 2017

16

Jan H Veldink

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2 September 2017

15

Paul W van Vught

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2 September 2017

1

Annelies Van Hoecke

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2 September 2017

10

Bénédicte Dubois

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2 September 2017

4

Mieke Timmers

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2 September 2017

21

Robert H Brown

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2 September 2017

Lies Schoonaert

2

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2 September 2017

Elke Peeters

7

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2 September 2017

Thomas Philips

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2 September 2017

Paloma Gonzalez-Perez

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2 September 2017

language of work or name

English

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publication date

1 September 2012

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2 September 2017

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2 September 2017

18

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2 September 2017

1418-1422

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2 September 2017

9

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https://scigraph.springernature.com/pub.10.1038/nm.2901

2 September 2017

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cites work

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

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Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS

21 January 2018

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A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD

21 January 2018

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Anticipation and phenotypic heterogeneity in korean familial amyotrophic lateral sclerosis with superoxide dismutase 1 gene mutation

21 January 2018

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Overexpression of mutant superoxide dismutase 1 causes a motor axonopathy in the zebrafish

21 January 2018

1 reference

Progranulin is neurotrophic in vivo and protects against a mutant TDP-43 induced axonopathy

21 January 2018

1 reference

EphA4 is required for cell adhesion and rhombomere-boundary formation in the zebrafish.

21 January 2018

1 reference

Bidirectional modulation of synaptic functions by Eph/ephrin signaling.

21 January 2018

1 reference

EphA4 (Sek1) receptor tyrosine kinase is required for the development of the corticospinal tract

21 January 2018

1 reference

Role of EphA4 and EphrinB3 in local neuronal circuits that control walking

21 January 2018

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Small molecules can selectively inhibit ephrin binding to the EphA4 and EphA2 receptors

21 January 2018

1 reference

Axonal regeneration and lack of astrocytic gliosis in EphA4-deficient mice

21 January 2018

1 reference

Regeneration-enhancing effects of EphA4 blocking peptide following corticospinal tract injury in adult rat spinal cord

21 January 2018

1 reference

EphA4 blockers promote axonal regeneration and functional recovery following spinal cord injury in mice

21 January 2018

1 reference

Neuron-glia communication via EphA4/ephrin-A3 modulates LTP through glial glutamate transport

21 January 2018

1 reference

Decreased glutamate transport by the brain and spinal cord in amyotrophic lateral sclerosis

21 January 2018

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Selective loss of glial glutamate transporter GLT-1 in amyotrophic lateral sclerosis

21 January 2018

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Beta-lactam antibiotics offer neuroprotection by increasing glutamate transporter expression.

21 January 2018

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Matching between motoneurone and muscle unit properties in rat medial gastrocnemius.

21 January 2018

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Transcriptional profiling of Alzheimer blood mononuclear cells by microarray

21 January 2018

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Genome-wide expression profiling of human blood reveals biomarkers for Huntington's disease.

21 January 2018

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Lymphocytes as a neural probe: potential for studying psychiatric disorders

21 January 2018

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Comparative gene expression analysis of blood and brain provides concurrent validation of SELENBP1 up-regulation in schizophrenia

21 January 2018

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Fibroblast and lymphoblast gene expression profiles in schizophrenia: are non-neural cells informative?

21 January 2018

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Assessing the validity of blood-based gene expression profiles for the classification of schizophrenia and bipolar disorder: a preliminary report

21 January 2018

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Unraveling the regulatory mechanisms underlying tissue-dependent genetic variation of gene expression

21 January 2018

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TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis

21 January 2018

1 reference

Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

21 January 2018

1 reference

TDP-43 A315T mutation in familial motor neuron disease

21 January 2018

1 reference

Knockdown of the survival motor neuron (Smn) protein in zebrafish causes defects in motor axon outgrowth and pathfinding.

21 January 2018

1 reference

Treatment of motoneuron degeneration by intracerebroventricular delivery of VEGF in a rat model of ALS.

21 January 2018

1 reference

Neuroblastoma x spinal cord (NSC) hybrid cell lines resemble developing motor neurons

21 January 2018

1 reference

Age at onset in sod1-mediated amyotrophic lateral sclerosis shows familiality

21 January 2018

1 reference

Early and selective loss of neuromuscular synapse subtypes with low sprouting competence in motoneuron diseases

21 January 2018

1 reference

12 December 2020

Expression of truncated Sek-1 receptor tyrosine kinase disrupts the segmental restriction of gene expression in the Xenopus and zebrafish hindbrain.

1 reference

12 December 2020

Physiological properties of motoneurons innervating different muscle unit types in rat gastrocnemius

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12 December 2020

Selective vulnerability and pruning of phasic motoneuron axons in motoneuron disease alleviated by CNTF

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12 December 2020

Phenotypic Heterogeneity in a SOD1 G93D Italian ALS Family: An Example of Human Model to Study a Complex Disease

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12 December 2020

Identifiers

DOI

10.1038/NM.2901

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Dimensions Publication ID

2 September 2017

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