Dissecting negative symptoms in schizophrenia: opportunities for translation into new treatments (Q38291334)

1 September 2017

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title

Dissecting negative symptoms in schizophrenia: opportunities for translation into new treatments (English)

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1 September 2017

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5

Gary Remington

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1 September 2017

3

Gagan Fervaha

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1 September 2017

4

Ofer Agid

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1 September 2017

1

George Foussias

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1 September 2017

2

Ishraq Siddiqui

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PubMed ID

25516370

1 September 2017

language of work or name

English

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publication date

16 December 2014

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Journal of Psychopharmacology

1 September 2017

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1 September 2017

29

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1 September 2017

2

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1 September 2017

116-126

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Temporal discounting of rewards in patients with bipolar disorder and schizophrenia

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Prosody and lexical accuracy in flat affect schizophrenia

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A comparison of clinical ratings with vocal acoustic measures of flat affect and alogia

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Validation of a 4-item Negative Symptom Assessment (NSA-4): a short, practical clinical tool for the assessment of negative symptoms in schizophrenia.

21 January 2018

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Computerized measurement of facial expression of emotions in schizophrenia

21 January 2018

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Negative symptoms in schizophrenia. Definition and reliability

21 January 2018

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Negative v positive schizophrenia. Definition and validation.

21 January 2018

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A critique of fixed and progressive ratio schedules used to examine the neural substrates of drug reinforcement

21 January 2018

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Differential regulation of the consummatory, motivational and anticipatory aspects of feeding behavior by dopaminergic and opioidergic drugs

21 January 2018

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Goal representations and motivational drive in schizophrenia: the role of prefrontal-striatal interactions

21 January 2018

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Effort, anhedonia, and function in schizophrenia: reduced effort allocation predicts amotivation and functional impairment

21 January 2018

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Dopamine modulates effort-based decision making in rats

21 January 2018

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Anhedonia, avolition, and anticipatory deficits: assessments in animals with relevance to the negative symptoms of schizophrenia

21 January 2018

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Insensitivity to future consequences following damage to human prefrontal cortex

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21 January 2018

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The structure of negative symptoms within schizophrenia: implications for assessment.

21 January 2018

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Examining the latent structure of negative symptoms: is there a distinct subtype of negative symptom schizophrenia?

21 January 2018

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Persistent negative symptoms in schizophrenia: an overview

21 January 2018

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Construct validity of the Iowa Gambling Task

21 January 2018

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Behavioral inhibition, behavioral activation, and affective responses to impending reward and punishment: The BIS/BAS Scales

21 January 2018

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Intrinsic motivation inventory: an adapted measure for schizophrenia research

21 January 2018

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Emotional experience in patients with schizophrenia revisited: meta-analysis of laboratory studies.

21 January 2018

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Double dissociation of basolateral and central amygdala lesions on the general and outcome-specific forms of pavlovian-instrumental transfer.

21 January 2018

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Molecular pathology of schizophrenia: more than one disease process?

21 January 2018

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The neurobiology of anhedonia and other reward-related deficits

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Assessment of reward responsiveness in the response bias probabilistic reward task in rats: implications for cross-species translational research

21 January 2018

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Animal models for the negative symptoms of schizophrenia

21 January 2018

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Apathy in first episode psychosis patients: a ten year longitudinal follow-up study.

21 January 2018

1 reference

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Apathy and functioning in first-episode psychosis.

21 January 2018

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Natural history of schizophrenia subtypes. II. Positive and negative symptoms and long-term course

21 January 2018

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Impact of primary negative symptoms on functional outcomes in schizophrenia.

21 January 2018

1 reference

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Incentive motivation deficits in schizophrenia reflect effort computation impairments during cost-benefit decision-making

21 January 2018

1 reference

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Dopaminergic and glutamatergic regulation of effort- and delay-based decision making.

21 January 2018

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A further evaluation of decision-making under risk and under ambiguity in schizophrenia

21 January 2018

1 reference

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Negative symptoms in schizophrenia: avolition and Occam's razor

21 January 2018

1 reference

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Negative symptoms of schizophrenia: clinical features, relevance to real world functioning and specificity versus other CNS disorders

21 January 2018

1 reference

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Motivational deficits as the central link to functioning in schizophrenia: a pilot study.

21 January 2018

1 reference

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Motivation and its relationship to neurocognition, social cognition, and functional outcome in schizophrenia

21 January 2018

1 reference

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Anhedonia in schizophrenia: distinctions between anticipatory and consummatory pleasure

21 January 2018

1 reference

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Negative symptoms of schizophrenia are associated with abnormal effort-cost computations

21 January 2018

1 reference

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Reward processing in schizophrenia: a deficit in the representation of value

21 January 2018

1 reference

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From perception to functional outcome in schizophrenia: modeling the role of ability and motivation

21 January 2018

1 reference

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Neurocognitive deficits and functional outcome in schizophrenia: are we measuring the "right stuff"?

21 January 2018

1 reference

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Automated Facial Action Coding System for dynamic analysis of facial expressions in neuropsychiatric disorders

21 January 2018

1 reference

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Patients with schizophrenia demonstrate dissociation between affective experience and motivated behavior

21 January 2018

1 reference

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Decision-making impairments in the context of intact reward sensitivity in schizophrenia

21 January 2018

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Imagining the future: degraded representations of future rewards and events in schizophrenia

21 January 2018

1 reference

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Delay discounting in schizophrenia

21 January 2018

1 reference

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Anhedonia in schizophrenia: a review of assessment strategies

21 January 2018

1 reference

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Identifying persistent negative symptoms in first episode psychosis

21 January 2018

1 reference

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Negative symptoms and psychosocial functioning in schizophrenia: neglected but important targets for treatment.

21 January 2018

1 reference

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Research domain criteria (RDoC): toward a new classification framework for research on mental disorders

21 January 2018

1 reference

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The positive and negative syndrome scale (PANSS) for schizophrenia

21 January 2018

1 reference

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Apathy in schizophrenia: clinical correlates and association with functional outcome.

21 January 2018

1 reference

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Disturbances of motivational balance in chronic schizophrenia during decision-making tasks.

21 January 2018

1 reference

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The Schedule for the Deficit syndrome: an instrument for research in schizophrenia.

21 January 2018

1 reference

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A separate disease within the syndrome of schizophrenia

21 January 2018

1 reference

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The NIMH-MATRICS consensus statement on negative symptoms

21 January 2018

1 reference

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The brief negative symptom scale: psychometric properties

21 January 2018

1 reference

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Apathy, cognitive deficits and functional impairment in schizophrenia.

21 January 2018

1 reference

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Emotional response deficits in schizophrenia: insights from affective science

21 January 2018

1 reference

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The Clinical Assessment Interview for Negative Symptoms (CAINS): final development and validation

21 January 2018

1 reference

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Video-based quantification of body movement during social interaction indicates the severity of negative symptoms in patients with schizophrenia

21 January 2018

1 reference

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Social interaction deficits caused by chronic phencyclidine administration are reversed by oxytocin

21 January 2018

1 reference

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Dissociation of emotional decision-making from cognitive decision-making in chronic schizophrenia.

21 January 2018

1 reference

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Determinants of everyday outcomes in schizophrenia: the influences of cognitive impairment, functional capacity, and symptoms.

21 January 2018

1 reference

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Measuring hedonic capacity in depression: a psychometric analysis of three anhedonia scales.

21 January 2018

1 reference

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Looking at the other side of the coin: a meta-analysis of self-reported emotional arousal in people with schizophrenia

21 January 2018

1 reference

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Anhedonia and negative symptomatology in chronic schizophrenia.

21 January 2018

1 reference

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Spared and impaired aspects of motivated cognitive control in schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881114562092

Methodological issues in negative symptom trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881114562092

Reliability and validity of the apathy evaluation scale

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881114562092

Construct validity of a self-stimulation threshold paradigm: Effects of reward and performance manipulations

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881114562092

Measuring reinforcement learning and motivation constructs in experimental animals: relevance to the negative symptoms of schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881114562092

Avolition and expressive deficits capture negative symptom phenomenology: implications for DSM-5 and schizophrenia research

21 January 2018

1 reference

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Predictive values of neurocognition and negative symptoms on functional outcome in schizophrenia: a longitudinal first-episode study with 7-year follow-up.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881114562092

Negative symptoms of schizophrenia: clinical characteristics, pathophysiological substrates, experimental models and prospects for improved treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881114562092

Incentive motivation in first-episode psychosis: a behavioural study

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881114562092

Intrinsic motivation, neurocognition and psychosocial functioning in schizophrenia: testing mediator and moderator effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881114562092

Anhedonia: a construct validation approach.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881114562092

Toward an objective characterization of an anhedonic phenotype: a signal-detection approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881114562092

Negative symptoms have greater impact on functioning than positive symptoms in schizophrenia: analysis of CATIE data

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881114562092

The negative symptoms of schizophrenia: a cognitive perspective

21 January 2018

1 reference

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Do patients with schizophrenia exhibit aberrant salience?

21 January 2018

1 reference

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21 January 2018

1 reference

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Anhedonia or anergia? Effects of haloperidol and nucleus accumbens dopamine depletion on instrumental response selection in a T-maze cost/benefit procedure.

21 January 2018

1 reference

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Haloperidol and nucleus accumbens dopamine depletion suppress lever pressing for food but increase free food consumption in a novel food choice procedure.

21 January 2018

1 reference

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Automation of the social interaction test by a video-tracking system: behavioural effects of repeated phencyclidine treatment.

21 January 2018

1 reference

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Social cognition as a mediator variable between neurocognition and functional outcome in schizophrenia: empirical review and new results by structural equation modeling

21 January 2018

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Schizophrenia patients demonstrate a distinctive pattern of decision-making impairment on the Iowa Gambling Task

21 January 2018

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Modeling risky decision making in rodents

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Schizophrenia in translation: dissecting motivation in schizophrenia and rodents.

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Auditory emotion recognition impairments in schizophrenia: relationship to acoustic features and cognition

21 January 2018

1 reference

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Deconstructing negative symptoms of schizophrenia: avolition-apathy and diminished expression clusters predict clinical presentation and functional outcome

21 January 2018

1 reference

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Anticipatory vs. consummatory pleasure: what is the nature of hedonic deficits in schizophrenia?

21 January 2018

1 reference

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Schizophrenia, "just the facts" what we know in 2008. 2. Epidemiology and etiology

21 January 2018

1 reference

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Schizophrenia, "just the facts" 4. Clinical features and conceptualization

21 January 2018

1 reference

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Recognizing Action Units for Facial Expression Analysis

21 January 2018

1 reference

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Worth the 'EEfRT'? The effort expenditure for rewards task as an objective measure of motivation and anhedonia

21 January 2018

1 reference

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A novel set-shifting modification of the iowa gambling task: flexible emotion-based learning in schizophrenia.

21 January 2018

1 reference

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Orbitofrontal cortex and its contribution to decision-making

21 January 2018

1 reference

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Selective reinforcement learning deficits in schizophrenia support predictions from computational models of striatal-cortical dysfunction

21 January 2018

1 reference

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Abnormal responses to monetary outcomes in cortex, but not in the basal ganglia, in schizophrenia

21 January 2018

1 reference

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Automated video-based facial expression analysis of neuropsychiatric disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881114562092

Social interaction and social withdrawal in rodents as readouts for investigating the negative symptoms of schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881114562092

Characterization of the facial expression of emotions in schizophrenia patients: preliminary findings with a new electromyography method.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881114562092

The Lille Apathy Rating Scale (LARS): exploring its psychometric properties in schizophrenia.

21 January 2018

1 reference

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Risk/reward decision-making in schizophrenia: a preliminary examination of the influence of tobacco smoking and relationship to Wisconsin Card Sorting Task performance

21 January 2018

1 reference

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Serotonergic and dopaminergic modulation of gambling behavior as assessed using a novel rat gambling task.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881114562092

Apathy in first episode psychosis patients: One year follow up

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881114562092

Assessing apathy: The use of the Apathy Evaluation Scale in first episode psychosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881114562092

21 January 2018

Identifiers

DOI

10.1177/0269881114562092

1 reference

1 September 2017

1 reference

PubMed ID

25516370