Structural polymorphism within a regulatory element of the human KRAS promoter: formation of G4-DNA recognized by nuclear proteins (Q38290815)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18490377%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

title

Structural polymorphism within a regulatory element of the human KRAS promoter: formation of G4-DNA recognized by nuclear proteins (English)

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7 January 2020

4

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7 January 2020

author name string

Susanna Cogoi

series ordinal

1

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7 January 2020

Manikandan Paramasivam

series ordinal

2

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7 January 2020

Barbara Spolaore

series ordinal

3

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7 January 2020

language of work or name

English

0 references

publication date

19 May 2008

1 reference

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7 January 2020

number of pages

16

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inferred from page(s)

published in

Nucleic Acids Research

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7 January 2020

volume

36

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7 January 2020

issue

11

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7 January 2020

page(s)

3765-3780

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A sequence-independent study of the influence of short loop lengths on the stability and topology of intramolecular DNA G-quadruplexes

7 January 2020

cites work

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6 September 2017

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6 September 2017

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Small-molecule interaction with a five-guanine-tract G-quadruplex structure from the human MYC promoter

6 September 2017

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Synthesis and biological evaluation of new pentaphyrin macrocycles for photodynamic therapy

6 September 2017

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Evidence for the presence of a guanine quadruplex forming region within a polypurine tract of the hypoxia inducible factor 1alpha promoter

6 September 2017

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6 September 2017

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Facilitation of a structural transition in the polypurine/polypyrimidine tract within the proximal promoter region of the human VEGF gene by the presence of potassium and G-quadruplex-interactive agents

6 September 2017

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Development of farnesyl transferase inhibitors: a review

6 September 2017

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Thermal difference spectra: a specific signature for nucleic acid structures.

6 September 2017

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Transcription inhibition of oncogenic KRAS by a mutation-selective peptide nucleic acid conjugated to the PKKKRKV nuclear localization signal peptide.

6 September 2017

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Formation and properties of hairpin and tetraplex structures of guanine-rich regulatory sequences of muscle-specific genes

6 September 2017

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Vertebrate telomere repeat DNAs favor external loop propeller quadruplex structures in the presence of high concentrations of potassium

6 September 2017

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Propeller-type parallel-stranded G-quadruplexes in the human c-myc promoter

6 September 2017

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6 September 2017

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Antiproliferative activity of a triplex-forming oligonucleotide recognizing a Ki-ras polypurine/polypyrimidine motif correlates with protein binding

6 September 2017

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Structure-based incorporation of 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine into the human telomeric repeat DNA as a probe for UP1 binding and destabilization of G-tetrad structures

6 September 2017

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6 September 2017

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A proteomic approach to the identification of heterogeneous nuclear ribonucleoproteins as a new family of poly(ADP-ribose)-binding proteins

6 September 2017

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6 September 2017

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Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription

6 September 2017

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Fluorescence resonance energy transfer as a probe for G-quartet formation by a telomeric repeat

6 September 2017

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Dimeric DNA quadruplex containing major groove-aligned A-T-A-T and G-C-G-C tetrads stabilized by inter-subunit Watson-Crick A-T and G-C pairs

6 September 2017

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Antisense treatment directed against mutated Ki-ras in human colorectal adenocarcinoma

6 September 2017

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6 September 2017

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Human Ku antigen tightly binds and stabilizes a tetrahelical form of the Fragile X syndrome d(CGG)n expanded sequence

6 September 2017

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Ku autoantigen: a multifunctional DNA-binding protein

6 September 2017

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Probability-based protein identification by searching sequence databases using mass spectrometry data

6 September 2017

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Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo

6 September 2017

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DNA tetraplex formation in the control region of c-myc

6 September 2017

1 reference

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Sequence-specific antitumor activity of a phosphorothioate oligodeoxyribonucleotide targeted to human C-raf kinase supports an antisense mechanism of action in vivo

6 September 2017

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Heterogeneous nuclear ribonucleoprotein K is a transcription factor

6 September 2017

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EBP-80, a transcription factor closely resembling the human autoantigen Ku, recognizes single- to double-strand transitions in DNA.

6 September 2017

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Chromatin structure of the promoter region of the human c-K-ras gene

6 September 2017

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6 September 2017

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Site-specific oligonucleotide binding represses transcription of the human c-myc gene in vitro

6 September 2017

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Nuclease hypersensitive sites in chromatin

6 September 2017

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Inhibition of purified p21ras farnesyl:protein transferase by Cys-AAX tetrapeptides

6 September 2017

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Effect of primary and secondary structure of oligodeoxyribonucleotides on the fluorescent properties of conjugated dyes

6 September 2017

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Enzymatic and antisense effects of a specific anti-Ki-ras ribozyme in vitro and in cell culture

14 September 2017

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G-quadruplexes in promoters throughout the human genome

14 September 2017

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Initial characterization of a potential transcriptional enhancer for the human c-K-ras gene.

23 June 2018

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Characterization of the human c-K-ras gene promoter.

23 June 2018

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Glycine to aspartic acid mutations at codon 13 of the c-Ki-ras gene in human gastrointestinal cancers

23 June 2018

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Trisubstituted isoalloxazines as a new class of G-quadruplex binding ligands: small molecule regulation of c-kit oncogene expression

23 June 2018

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Gene function correlates with potential for G4 DNA formation in the human genome

31 August 2018

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DNA transitions induced by binding of PARP-1 to cruciform structures in supercoiled plasmids.

31 August 2018

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Stabilization of guanine quadruplex DNA by the binding of porphyrins with cationic side arms

31 August 2018

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Design and synthesis of an expanded porphyrin that has selectivity for the c-MYC G-quadruplex structure

31 August 2018

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Formation of an interlocked quadruplex dimer by d(GGGT).

31 August 2018

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RAS oncogenes: the first 30 years.

31 August 2018

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Synthesis and characterization of DNA quadruplexes containing T-tetrads formed by bunch-oligonucleotides

31 August 2018

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Crossref

https://api.crossref.org/works/10.1093%2FNAR%2FGKN120

Sequence-specific DNA binding by Ku autoantigen and its effects on transcription

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FNAR%2FGKN120

Specific binding of poly(ADP-ribose) polymerase-1 to cruciform hairpins

21 January 2018

1 reference

12 December 2020

Selective interactions of cationic porphyrins with G-quadruplex structures

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12 December 2020

Re: Blocking Oncogenic Ras Signaling for Cancer Therapy

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12 December 2020

The dynamic character of the G-quadruplex element in the c-MYC promoter and modification by TMPyP4

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12 December 2020

c-K-ras mutations in human carcinomas occur preferentially in codon 12

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12 December 2020

Growth inhibition of human pancreatic cancer cell lines by anti-sense oligonucleotides specific to mutated K-ras genes

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12 December 2020

Identifiers

DOI

10.1093/NAR/GKN120

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18490377%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18490377%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1 reference