Caspase cleavage product lacking amino-terminus of IkappaBalpha sensitizes resistant cells to TNF-alpha and TRAIL-induced apoptosis (Q38290263)

1 September 2017

title

Caspase cleavage product lacking amino-terminus of IkappaBalpha sensitizes resistant cells to TNF-alpha and TRAIL-induced apoptosis (English)

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1 September 2017

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9

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1 September 2017

Dong-Gyu Jo

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author name string

Ki-Woo Kim

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1 September 2017

Byung Ju Kim

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Chul-Woong Chung

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In-Ki Kim

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You-Hyun Song

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Yun-Kyung Kwon

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Ha-Na Woo

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1 September 2017

publication date

1 January 2002

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Journal of Cellular Biochemistry

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published in

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volume

85

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issue

2

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1 September 2017

page(s)

334-345

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Human ICE/CED-3 protease nomenclature

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cites work

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Critical role for lysines 21 and 22 in signal-induced, ubiquitin-mediated proteolysis of I kappa B-alpha

21 January 2018

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Phosphorylation of IkappaB-alpha inhibits its cleavage by caspase CPP32 in vitro

21 January 2018

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An essential role for NF-kappaB in preventing TNF-alpha-induced cell death

21 January 2018

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Pyrrolidine dithiocarbamate, a potent inhibitor of nuclear factor kappa B (NF-kappa B) activation, prevents apoptosis in human promyelocytic leukemia HL-60 cells and thymocytes

21 January 2018

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Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation

21 January 2018

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Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway

21 January 2018

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Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NF-kappaB control

21 January 2018

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Proapoptotic effects of tau cleavage product generated by caspase-3.

21 January 2018

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The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain

21 January 2018

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Involvement of an ICE-like protease in Fas-mediated apoptosis

21 January 2018

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Mechanistic aspects of NF-kappa B regulation: the emerging role of phosphorylation and proteolysis

21 January 2018

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Energy metabolism during apoptosis. Bcl-2 promotes survival in hematopoietic cells induced to apoptose by growth factor withdrawal by stabilizing a form of metabolic arrest

21 January 2018

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The I kappa B proteins: members of a multifunctional family

21 January 2018

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Tumor necrosis factor-alpha-inducible IkappaBalpha proteolysis mediated by cytosolic m-calpain. A mechanism parallel to the ubiquitin-proteasome pathway for nuclear factor-kappab activation

21 January 2018

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A general method of in vitro preparation and specific mutagenesis of DNA fragments: study of protein and DNA interactions

21 January 2018

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Tumor necrosis factor-related apoptosis-inducing ligand receptors signal NF-kappaB and JNK activation and apoptosis through distinct pathways

21 January 2018

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ERICE, a novel FLICE-activatable caspase

21 January 2018

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Caspase-induced inactivation of the anti-apoptotic TRAF1 during Fas ligand-mediated apoptosis

21 January 2018

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Correction of radiation sensitivity in ataxia telangiectasia cells by a truncated I kappa B-alpha

21 January 2018

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Suppression of interleukin-1 beta-converting enzyme-mediated cell death by insulin-like growth factor

21 January 2018

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Apoptosis. Its significance in cancer and cancer therapy

21 January 2018

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Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice

21 January 2018

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Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9

21 January 2018

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Apoptosis overrides survival signals through a caspase-mediated dominant-negative NF-kappa B loop

21 January 2018

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Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis

21 January 2018

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Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death

21 January 2018

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Tumor necrosis factor-induced apoptosis is mediated by a CrmA-sensitive cell death pathway

21 January 2018

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Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

21 January 2018

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Caspase structure, proteolytic substrates, and function during apoptotic cell death

21 January 2018

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Caspases: killer proteases

21 January 2018

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Viral inhibition of inflammation: cowpox virus encodes an inhibitor of the interleukin-1 beta converting enzyme

21 January 2018

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Apoptosis promotes a caspase-induced amino-terminal truncation of IkappaBalpha that functions as a stable inhibitor of NF-kappaB.

21 January 2018

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Caspases as treatment targets in stroke and neurodegenerative diseases

21 January 2018

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Nuclear factor (NF)-kappaB-regulated X-chromosome-linked iap gene expression protects endothelial cells from tumor necrosis factor alpha-induced apoptosis.

21 January 2018

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Fas- and tumor necrosis factor-induced apoptosis is inhibited by the poxvirus crmA gene product

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Caspases: enemies within

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CD95 and TRAIL receptor-mediated activation of protein kinase C and NF-kappaB contributes to apoptosis resistance in ductal pancreatic adenocarcinoma cells

21 January 2018

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Life and death decisions: regulation of apoptosis by proteolysis of signaling molecules

21 January 2018

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Suppression of TNF-alpha-induced apoptosis by NF-kappaB

21 January 2018

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Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally.

21 January 2018

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TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

21 January 2018

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NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation

21 January 2018

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N- and C-terminal sequences control degradation of MAD3/I kappa B alpha in response to inducers of NF-kappa B activity

21 January 2018

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IEX-1L, an apoptosis inhibitor involved in NF-kappaB-mediated cell survival

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Apoptosis in the nervous system

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Peptide inhibitors of the ICE protease family arrest programmed cell death of motoneurons in vivo and in vitro

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Caspases: the proteases of the apoptotic pathway

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21 January 2018

Identifiers

DOI

10.1002/JCB.10139

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1 September 2017

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