VEGF, Notch and TGFβ/BMPs in regulation of sprouting angiogenesis and vascular patterning (Q38268447)

1 September 2017

1 reference

title

VEGF, Notch and TGFβ/BMPs in regulation of sprouting angiogenesis and vascular patterning (English)

1 reference

1 September 2017

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25399573%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Lars Jakobsson

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25399573%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

author name string

David Kaluza

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25399573%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

publication date

1 December 2014

1 reference

Biochemical Society Transactions

1 September 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25399573%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

volume

42

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25399573%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25399573%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

page(s)

1576-1583

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25399573%20AND%20SRC:MED&resulttype=core&format=json

Molecular control of endothelial cell behaviour during blood vessel morphogenesis

8 June 2020

cites work

1 reference

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VEGF and Notch in tip and stalk cell selection

21 January 2018

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Robustness in angiogenesis: notch and BMP shaping waves

21 January 2018

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Flt1 acts as a negative regulator of tip cell formation and branching morphogenesis in the zebrafish embryo

21 January 2018

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Elevated vascular endothelial growth factor receptor-2 abundance contributes to increased angiogenesis in vascular endothelial growth factor receptor-1-deficient mice

21 January 2018

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ALK1 signaling inhibits angiogenesis by cooperating with the Notch pathway.

21 January 2018

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Stalk cell phenotype depends on integration of Notch and Smad1/5 signaling cascades

21 January 2018

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BMP9 regulates endoglin-dependent chemokine responses in endothelial cells

21 January 2018

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Notch as a hub for signaling in angiogenesis.

21 January 2018

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HESR1/CHF2 suppresses VEGFR2 transcription independent of binding to E-boxes

21 January 2018

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Regulation of Notch1 and Dll4 by vascular endothelial growth factor in arterial endothelial cells: implications for modulating arteriogenesis and angiogenesis

21 January 2018

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Endothelial cells dynamically compete for the tip cell position during angiogenic sprouting

21 January 2018

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Neuropilin regulation of angiogenesis, arteriogenesis, and vascular permeability

21 January 2018

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Ephrin-B2 regulates VEGFR2 function in developmental and tumour angiogenesis

21 January 2018

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Spatial regulation of VEGF receptor endocytosis in angiogenesis

21 January 2018

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Crosstalk between vascular endothelial growth factor, notch, and transforming growth factor-beta in vascular morphogenesis

21 January 2018

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TGFbeta-SMAD signal transduction: molecular specificity and functional flexibility

21 January 2018

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Non-Smad TGF-beta signals

21 January 2018

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Non-Smad pathways in TGF-beta signaling

21 January 2018

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Transforming growth factor β family members in regulation of vascular function: in the light of vascular conditional knockouts

21 January 2018

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Balancing the activation state of the endothelium via two distinct TGF-beta type I receptors

21 January 2018

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Nonoverlapping expression patterns of ALK1 and ALK5 reveal distinct roles of each receptor in vascular development

21 January 2018

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Defective retinal vascular endothelial cell development as a consequence of impaired integrin αVβ8-mediated activation of transforming growth factor-β.

21 January 2018

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Bone morphogenetic protein-9 is a circulating vascular quiescence factor

21 January 2018

1 reference

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BMP9 is produced by hepatocytes and circulates mainly in an active mature form complexed to its prodomain.

21 January 2018

1 reference

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BMP9 and BMP10 are critical for postnatal retinal vascular remodeling.

21 January 2018

1 reference

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BMP9 induces EphrinB2 expression in endothelial cells through an Alk1-BMPRII/ActRII-ID1/ID3-dependent pathway: implications for hereditary hemorrhagic telangiectasia type II.

21 January 2018

1 reference

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Identification of BMP9 and BMP10 as functional activators of the orphan activin receptor-like kinase 1 (ALK1) in endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140231

BMP-9 signals via ALK1 and inhibits bFGF-induced endothelial cell proliferation and VEGF-stimulated angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140231

BMP-9 induces proliferation of multiple types of endothelial cells in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140231

Context-dependent signaling defines roles of BMP9 and BMP10 in embryonic and postnatal development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140231

Bone morphogenetic protein 9 (BMP9) controls lymphatic vessel maturation and valve formation

21 January 2018

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Bone morphogenetic protein-9 inhibits lymphatic vessel formation via activin receptor-like kinase 1 during development and cancer progression.

21 January 2018

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Endoglin promotes endothelial cell proliferation and TGF-beta/ALK1 signal transduction

21 January 2018

1 reference

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Endoglin null endothelial cells proliferate faster and are more responsive to transforming growth factor beta1 with higher affinity receptors and an activated Alk1 pathway

21 January 2018

1 reference

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Endoglin promotes transforming growth factor beta-mediated Smad 1/5/8 signaling and inhibits endothelial cell migration through its association with GIPC.

21 January 2018

1 reference

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The interaction of endoglin with beta-arrestin2 regulates transforming growth factor-beta-mediated ERK activation and migration in endothelial cells

21 January 2018

1 reference

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Endoglin controls cell migration and composition of focal adhesions: function of the cytosolic domain

21 January 2018

1 reference

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Mouse model for hereditary hemorrhagic telangiectasia has a generalized vascular abnormality

21 January 2018

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A mouse model for hereditary hemorrhagic telangiectasia (HHT) type 2.

21 January 2018

1 reference

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VEGF Induces More Severe Cerebrovascular Dysplasia in Endoglin than in Alk1 Mice

21 January 2018

1 reference

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Endothelial depletion of Acvrl1 in mice leads to arteriovenous malformations associated with reduced endoglin expression

21 January 2018

1 reference

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Novel brain arteriovenous malformation mouse models for type 1 hereditary hemorrhagic telangiectasia

21 January 2018

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ALK5- and TGFBR2-independent role of ALK1 in the pathogenesis of hereditary hemorrhagic telangiectasia type 2

21 January 2018

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Interaction between alk1 and blood flow in the development of arteriovenous malformations

21 January 2018

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Endothelial expression of TGFβ type II receptor is required to maintain vascular integrity during postnatal development of the central nervous system

21 January 2018

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Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140231

The Notch ligand Delta-like 4 negatively regulates endothelial tip cell formation and vessel branching.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140231

Delta-like ligand 4 (Dll4) is induced by VEGF as a negative regulator of angiogenic sprouting

21 January 2018

1 reference

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Defective paracrine signalling by TGFbeta in yolk sac vasculature of endoglin mutant mice: a paradigm for hereditary haemorrhagic telangiectasia

21 January 2018

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Synergy and antagonism between Notch and BMP receptor signaling pathways in endothelial cells.

21 January 2018

1 reference

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ChIP-seq reveals cell type-specific binding patterns of BMP-specific Smads and a novel binding motif

21 January 2018

1 reference

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Notch-1 signalling is activated in brain arteriovenous malformations in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140231

Endothelial Notch signaling is upregulated in human brain arteriovenous malformations and a mouse model of the disease

21 January 2018

1 reference

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Notch4 is activated in endothelial and smooth muscle cells in human brain arteriovenous malformations

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140231

Endothelial Notch4 signaling induces hallmarks of brain arteriovenous malformations in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140231

Constitutively active endothelial Notch4 causes lung arteriovenous shunts in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140231

Bevacizumab in patients with hereditary hemorrhagic telangiectasia and severe hepatic vascular malformations and high cardiac output

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140231

Improvement of ischemic cholangiopathy in three patients with hereditary hemorrhagic telangiectasia following treatment with bevacizumab

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140231

ENDOGLIN is dispensable for vasculogenesis, but required for vascular endothelial growth factor-induced angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140231

Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140231

Src-mediated post-translational regulation of endoglin stability and function is critical for angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140231

Do endothelial cells dream of eclectic shape?

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140231

EndMT contributes to the onset and progression of cerebral cavernous malformations

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140231

Genetic and pharmacological targeting of activin receptor-like kinase 1 impairs tumor growth and angiogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140231

BMP10 is essential for maintaining cardiac growth during murine cardiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140231

TGF-beta receptor type II deficiency results in defects of yolk sac hematopoiesis and vasculogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140231

Induced disruption of the transforming growth factor beta type II receptor gene in mice causes a lethal inflammatory disorder that is transplantable

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140231

BMP type II receptor is required for gastrulation and early development of mouse embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140231

BMPR-II heterozygous mice have mild pulmonary hypertension and an impaired pulmonary vascular remodeling response to prolonged hypoxia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140231

Genetic ablation of the BMPR2 gene in pulmonary endothelium is sufficient to predispose to pulmonary arterial hypertension.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140231

Arteriovenous malformations in mice lacking activin receptor-like kinase-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140231

Abnormal angiogenesis but intact hematopoietic potential in TGF-beta type I receptor-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140231

Compensatory signalling induced in the yolk sac vasculature by deletion of TGFbeta receptors in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140231

Defective angiogenesis in mice lacking endoglin

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140231

Generation of a floxed allele of the mouse Endoglin gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140231

Heart and liver defects and reduced transforming growth factor beta2 sensitivity in transforming growth factor beta type III receptor-deficient embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140231

The tumor suppressor gene Smad4/Dpc4 is required for gastrulation and later for anterior development of the mouse embryo

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140231

Essential role of endothelial Smad4 in vascular remodeling and integrity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140231

Endothelial Smad4 maintains cerebrovascular integrity by activating N-cadherin through cooperation with Notch.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140231

Inactivation of Smad5 in endothelial cells and smooth muscle cells demonstrates that Smad5 is required for cardiac homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140231

SMAD1 deficiency in either endothelial or smooth muscle cells can predispose mice to pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140231

Smad2/Smad3 in endothelium is indispensable for vascular stability via S1PR1 and N-cadherin expressions

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20140231

21 January 2018

Identifiers

DOI

10.1042/BST20140231

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25399573%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

1 reference