Total synthesis of (±)-phomactin A. Lessons learned from respecting a challenging structural topology (Q38267093)

1 September 2017

Total synthesis of (±)-phomactin A. Lessons learned from respecting a challenging structural topology (English)

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1 September 2017

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4

Richard P Hsung

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1 September 2017

Grant S Buchanan

1

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1 September 2017

Kevin P Cole

series ordinal

2

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1 September 2017

Yu Tang

series ordinal

3

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1 September 2017

language of work or name

English

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publication date

5 August 2011

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Journal of Organic Chemistry

1 September 2017

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1 September 2017

76

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1 September 2017

17

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1 September 2017

7027-7039

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Total Synthesis of Tovophyllin B.

1 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163054

Studies toward the synthesis of phomactin A. An approach to the macrocyclic core

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163054

The phomactins. A novel group of terpenoid platelet activating factor antagonists related biogenetically to the taxanes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163054

Platelet-activating factor, a pleiotrophic mediator of physiological and pathological processes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163054

The first total synthesis of (+/-)-arisugacin A, a potent, orally bioavailable inhibitor of acetylcholinesterase

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163054

Perspectives in platelet-activating factor research

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163054

An Enantioselective Synthesis of the ABD Tricycle for (-)-Phomactin A Featuring Rawal's Asymmetric Diels-Alder Cycloaddition

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163054

Platelet-activating factor mediates acid-induced lung injury in genetically engineered mice

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163054

Aza-[3 + 3] Annulations: A New Unified Strategy in Alkaloid Synthesis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163054

Total synthesis of phomactin A.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163054

Intramolecular cyclohexadienone annulations of Fischer carbene complexes: model studies for the synthesis of Phomactins

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163054

Studies directed toward the synthesis of the massileunicellins. 2.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163054

Diastereoselective synthesis of polycyclic acetal-fused pyrano[3,2-c]pyran-5(2H)-one derivatives

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163054

Investigation of an organomagnesium-based [3 + 3] annelation to pyrans and its application in the synthesis of rhopaloic acid A.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163054

Total synthesis of (+/-)-phomactin B2 via an intramolecular cyclohexadienone annulation of a chromium carbene complex

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163054

Unique structural topology and reactivities of the ABD tricycle in phomactin A.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163054

Palladium-catalyzed allylic transposition of (allyloxy) iminodiazaphospholidines: a formal [3,3]-aza-phospha-oxa-Cope sigmatropic rearrangement for the stereoselective synthesis of allylic amines

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163054

Biomimetic synthesis of antimalarial naphthoquinones

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163054

Highly selective 1,3-isomerization of allylic alcohols via rhenium oxo catalysis

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163054

Biosynthesis of phomactins: common intermediate phomactatriene and taxadiene

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163054

A modular and concise total synthesis of (+/-)-daurichromenic acid and analogues

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163054

Total synthesis of (+/-)-phomactin G, a platelet activating factor antagonist from the marine fungus Phoma sp.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163054

A total synthesis of (+/-)-phomactin A.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163054

Synthetic studies towards the phomactins. Concise syntheses of the tricyclic furanochroman and the oxygenated bicyclo[9.3.1]pentadecane ring systems in phomactin A.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163054

Synthetic studies towards congeners of phomactin A. Re-examination of the structure of Sch 49028.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163054

Structural determinants of blockade of eosinophil activation, adhesion and secretion by synthetic analogs of phomactin.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163054

Biomimetic synthesis of (+/-)-pinnatal and (+/-)-sterekunthal A.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163054

A formal [3 + 3] cycloaddition reaction. Improved reactivity using alpha,beta-unsaturated iminium salts and evidence for reversibility of 6pi-electron electrocyclic ring closure of 1-oxatrienes

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163054

Total synthesis of (+)-phomactin a using a B-alkyl Suzuki macrocyclization

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163054

A total synthesis of phomactin A.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163054

Allylic Transposition of Alcohol and Amine Functionality by Thermal or Palladium(II)-Catalyzed Rearrangements of Allylic N-Benzoylbenzimidates

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163054

A Sakurai−Prins−Ritter Sequence for the Three-Component Diastereoselective Synthesis of 4-Amino Tetrahydropyrans

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163054

Studies toward the tricyclic core of phomactin A. Synthesis of the reduced furanochroman subunit

3 December 2018

1 reference

12 December 2020

Synthesis of the ring system of phomactin D using a Suzuki macrocyclization

1 reference

12 December 2020

Transannular macrocyclization via intramolecular B-alkyl Suzuki reaction

1 reference

12 December 2020

A Nozaki-Hiyama-Kishi Ni(II)/Cr(II) coupling approach to the phomactins

1 reference

12 December 2020

Total syntheses of pyranoquinoline alkaloids: simulenoline, huajiaosimuline, and (+/-)-7-demethoxyzanthodioline

1 reference

12 December 2020

Enantioselective synthesis of the oxadecalin core of phomactin A via a highly stereoselective Diels-Alder reaction

1 reference

12 December 2020

Sequential 1,2-Addition-Electrocyclic Ring Closures Involving Acyclic alpha,beta-Unsaturated Iminiums: A Formal [3 + 3] Cycloaddition Strategy to Unique Pyranyl Spirocycles

1 reference

12 December 2020

Dihydropyrones as Dienophiles in the Diels-Alder Reaction: Application to the Synthesis of 1-Oxadecalones

1 reference

12 December 2020

Efficient assembly of the phomactin core via two different macrocyclization protocols

1 reference

12 December 2020

Domino Reactions in Organic Synthesis

1 reference

12 December 2020

Convergent enantioselective synthesis of the tricyclic core of phomactin A

1 reference

12 December 2020

Formal [3 + 3] Cycloaddition Approach to Chromenes and Chromanes. Concise Total Syntheses of (±)-Rhododaurichromanic Acids A and B and Methyl (±)-Daurichromenic Ester

1 reference

12 December 2020

Intramolecular formal oxa-[3 + 3] cycloaddition approach to the ABD system of phomactin A

1 reference

12 December 2020

Remarkable selectivity in addition of alcohols to epoxydienes of 5,7 bicyclic and 5,7,6 tricyclic systems

1 reference

12 December 2020

[3 + 3] Cycloadditions and related strategies in alkaloid natural product synthesis

1 reference

12 December 2020

A Lewis acid-catalyzed formal [3 + 3] cycloaddition of alpha,beta-unsaturated aldehydes with 4-hydroxy-2-pyrone, diketones, and vinylogous esters

1 reference

12 December 2020

Studies directed toward the synthesis of terreulactone A: rapid construction of the A, B, C rings

1 reference

12 December 2020

An unusual cationic [2 + 2] cycloaddition in a divergent total synthesis of hongoquercin A and rhododaurichromanic acid A

1 reference

12 December 2020

Facile synthesis of 1,3,7-trihydroxyxanthone and its regioselective coupling reactions with prenal: simple and efficient access to osajaxanthone and nigrolineaxanthone F

1 reference

12 December 2020

Regioselective Pd-catalyzed synthesis and application of 3-methyl-5-bromo-2-pyrone toward keto-phomactin A

1 reference

12 December 2020

A [3 + 3] annelation approach to (+)-rhopaloic acid B

1 reference

12 December 2020

A Concise Synthesis of the Pentacyclic Framework of Cortistatins

1 reference

12 December 2020

Synthesis of chromans via [3 + 3] cyclocoupling of phenols with allylic alcohols using a Mo/o-chloranil catalyst system

1 reference

12 December 2020

Beta-iodoallenolates as springboards for annulation reactions

1 reference

12 December 2020

Synthesis of the cyclohexane core of phomactins and a new route to the bicyclo[9.3.1]pentadecane diterpenoid skeleton

1 reference

12 December 2020

A Concise Stereoselective Route to the Pentacyclic Frameworks of Arisugacin A and Territrem B

1 reference

12 December 2020

Phomactin E, F, and G: new phomactin-group PAF antagonists from a marine fungus Phoma sp

1 reference

12 December 2020

A novel class of platelet activating factor antagonists from Phoma sp

1 reference

12 December 2020

Structure-activity relationships of phomactin derivatives as platelet activating factor antagonists

1 reference

12 December 2020

Identifiers

DOI

10.1021/JO200936R

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1 September 2017

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1 September 2017

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