Ovarian cancer: diagnostic, biological and prognostic aspects (Q38261795)

1 September 2017

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title

Ovarian cancer: diagnostic, biological and prognostic aspects (English)

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1 September 2017

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2

Claes G Tropé

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1 September 2017

Ben Davidson

1

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1 September 2017

1 September 2014

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1 September 2017

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1 September 2017

10

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1 September 2017

5

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1 September 2017

519-533

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1 September 2017

Cancer statistics, 2012

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Prognostic significance of residual tumor in patients with epithelial ovarian carcinoma stage IV in a 20 year perspective

21 January 2018

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Genetic testing by cancer site: ovary

21 January 2018

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The transcription factor FOXL2: at the crossroads of ovarian physiology and pathology

21 January 2018

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Recurrent somatic DICER1 mutations in nonepithelial ovarian cancers.

21 January 2018

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Ovarian carcinomas: five distinct diseases with different origins, genetic alterations, and clinicopathological features

21 January 2018

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Tumor cell type can be reproducibly diagnosed and is of independent prognostic significance in patients with maximally debulked ovarian carcinoma.

21 January 2018

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Biomarker-based ovarian carcinoma typing: a histologic investigation in the ovarian tumor tissue analysis consortium

21 January 2018

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Ovarian carcinoma histotype determination is highly reproducible, and is improved through the use of immunohistochemistry.

21 January 2018

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Value of PAX 8 immunostaining in tumor diagnosis: a review and update

21 January 2018

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WT1 expression in the female genital tract

21 January 2018

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Immunohistochemistry in the distinction between primary and metastatic ovarian mucinous neoplasms

21 January 2018

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Origin and pathogenesis of pelvic (ovarian, tubal, and primary peritoneal) serous carcinoma

21 January 2018

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TP53 mutations in serous tubal intraepithelial carcinoma and concurrent pelvic high-grade serous carcinoma--evidence supporting the clonal relationship of the two lesions

21 January 2018

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Key features of extrauterine pelvic serous tumours (fallopian tube, ovary, and peritoneum).

21 January 2018

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Pathology of primary and metastatic mucinous ovarian neoplasms

21 January 2018

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Identification of FGFR4 as a potential therapeutic target for advanced-stage, high-grade serous ovarian cancer

21 January 2018

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The ErbB signalling pathway: protein expression and prognostic value in epithelial ovarian cancer

21 January 2018

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PIK3CA overexpression is a possible prognostic factor for favorable survival in ovarian clear cell carcinoma

21 January 2018

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PIK3CA mutations and loss of ARID1A protein expression are early events in the development of cystic ovarian clear cell adenocarcinoma

21 January 2018

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Dickkopf-1 is frequently overexpressed in ovarian serous carcinoma and involved in tumor invasion.

21 January 2018

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Poly(adenosine diphosphate-ribose) polymerase expression in BRCA-proficient ovarian high-grade serous carcinoma; association with patient survival.

21 January 2018

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New strategies in the treatment of ovarian cancer: current clinical perspectives and future potential

21 January 2018

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The E3 ubiquitin ligase EDD is an adverse prognostic factor for serous epithelial ovarian cancer and modulates cisplatin resistance in vitro

21 January 2018

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BRCA1 is both a prognostic and predictive biomarker of response to chemotherapy in sporadic epithelial ovarian cancer

21 January 2018

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Pre-treatment tumor expression of ERCC1 in women with advanced stage epithelial ovarian cancer is not predictive of clinical outcomes: a Gynecologic Oncology Group study

21 January 2018

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Driver mutations in TP53 are ubiquitous in high grade serous carcinoma of the ovary

21 January 2018

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Prognostic and therapeutic impact of the chromosome 20q13.2 ZNF217 locus amplification in ovarian clear cell carcinoma

21 January 2018

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Expression of steroid receptor coactivator 3 in ovarian epithelial cancer is a poor prognostic factor and a marker for platinum resistance

21 January 2018

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Pair Box 8 (PAX8) protein expression in high grade, late stage (stages III and IV) ovarian serous carcinoma

21 January 2018

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Prognostic significance of tumor-infiltrating T cells in ovarian cancer: a meta-analysis.

21 January 2018

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Systematic analysis of immune infiltrates in high-grade serous ovarian cancer reveals CD20, FoxP3 and TIA-1 as positive prognostic factors

21 January 2018

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Low expression of the X-linked ribosomal protein S4 in human serous epithelial ovarian cancer is associated with a poor prognosis

21 January 2018

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Clear cell carcinomas of the ovary: a multi-institutional study of 129 cases in Korea with prognostic significance of Emi1 and Galectin-3.

21 January 2018

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AURKA and BRCA2 expression highly correlate with prognosis of endometrioid ovarian carcinoma

21 January 2018

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The autophagy protein LC3A correlates with hypoxia and is a prognostic marker of patient survival in clear cell ovarian cancer.

21 January 2018

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Hormone-receptor expression and ovarian cancer survival: an Ovarian Tumor Tissue Analysis consortium study

21 January 2018

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Role of TRAP1 and estrogen receptor alpha in patients with ovarian cancer -a study of the OVCAD consortium

21 January 2018

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Down-regulation of proteasomal subunit MB1 is an independent predictor of improved survival in ovarian cancer.

21 January 2018

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Novel molecular subtypes of serous and endometrioid ovarian cancer linked to clinical outcome

21 January 2018

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Validation of ovarian cancer gene expression signatures for survival and subtype in formalin fixed paraffin embedded tissues

21 January 2018

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Integrated genomic analyses of ovarian carcinoma

21 January 2018

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A DNA repair pathway-focused score for prediction of outcomes in ovarian cancer treated with platinum-based chemotherapy

21 January 2018

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Integrated analysis of multiple microarray datasets identifies a reproducible survival predictor in ovarian cancer

21 January 2018

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A seven-gene prognostic model for platinum-treated ovarian carcinomas

21 January 2018

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Microarray-based oncogenic pathway profiling in advanced serous papillary ovarian carcinoma

21 January 2018

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Stem cell-like gene expression in ovarian cancer predicts type II subtype and prognosis

21 January 2018

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Functional genomics identifies five distinct molecular subtypes with clinical relevance and pathways for growth control in epithelial ovarian cancer

21 January 2018

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Analysis of over 10,000 Cases finds no association between previously reported candidate polymorphisms and ovarian cancer outcome

21 January 2018

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Genetic analysis of cancer-implicated MicroRNA in ovarian cancer.

21 January 2018

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MicroRNA genes and their target 3'-untranslated regions are infrequently somatically mutated in ovarian cancers

21 January 2018

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MicroRNA processing and binding site polymorphisms are not replicated in the Ovarian Cancer Association Consortium

21 January 2018

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Akt2 regulates all Akt isoforms and promotes resistance to hypoxia through induction of miR-21 upon oxygen deprivation

21 January 2018

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Frequent downregulation of miR-34 family in human ovarian cancers

21 January 2018

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MicroRNA-138 suppresses ovarian cancer cell invasion and metastasis by targeting SOX4 and HIF-1α.

21 January 2018

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MiR-182 overexpression in tumourigenesis of high-grade serous ovarian carcinoma.

21 January 2018

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Regulation of miR-200 family microRNAs and ZEB transcription factors in ovarian cancer: evidence supporting a mesothelial-to-epithelial transition

21 January 2018

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miR-9 regulation of BRCA1 and ovarian cancer sensitivity to cisplatin and PARP inhibition

21 January 2018

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Downregulation of miRNA-31 induces taxane resistance in ovarian cancer cells through increase of receptor tyrosine kinase MET.

21 January 2018

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Involvement of microRNA-93, a new regulator of PTEN/Akt signaling pathway, in regulation of chemotherapeutic drug cisplatin chemosensitivity in ovarian cancer cells

21 January 2018

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A microRNA signature defines chemoresistance in ovarian cancer through modulation of angiogenesis

21 January 2018

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Let-7 modulates acquired resistance of ovarian cancer to Taxanes via IMP-1-mediated stabilization of multidrug resistance 1

21 January 2018

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Potential role of miR-9 and miR-223 in recurrent ovarian cancer

21 January 2018

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Identification of ovarian cancer metastatic miRNAs

21 January 2018

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miRNA profiling along tumour progression in ovarian carcinoma

21 January 2018

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miR-29b expression is associated with disease-free survival in patients with ovarian serous carcinoma.

21 January 2018

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Prognostic implications of microRNA-100 and its functional roles in human epithelial ovarian cancer

21 January 2018

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Regulation of ovarian cancer progression by microRNA-187 through targeting Disabled homolog-2.

21 January 2018

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A miR-200 microRNA cluster as prognostic marker in advanced ovarian cancer

21 January 2018

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Association between miR-200c and the survival of patients with stage I epithelial ovarian cancer: a retrospective study of two independent tumour tissue collections.

21 January 2018

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Upregulation of microRNA-203 is associated with advanced tumor progression and poor prognosis in epithelial ovarian cancer

21 January 2018

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A microRNA survival signature (MiSS) for advanced ovarian cancer.

21 January 2018

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Meta-analysis of transcriptome reveals let-7b as an unfavorable prognostic biomarker and predicts molecular and clinical subclasses in high-grade serous ovarian carcinoma.

21 January 2018

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Cancer-associated fibroblasts drive the progression of metastasis through both paracrine and mechanical pressure on cancer tissue

21 January 2018

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Fibroblasts as architects of cancer pathogenesis

21 January 2018

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Carcinoma-associated fibroblasts: non-neoplastic tumour-promoting mesenchymal cells.

21 January 2018

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Targeting the tumor microenvironment: from understanding pathways to effective clinical trials

21 January 2018

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No evidence of clonal somatic genetic alterations in cancer-associated fibroblasts from human breast and ovarian carcinomas

21 January 2018

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Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells

21 January 2018

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Exosomes: an overview of biogenesis, composition and role in ovarian cancer

21 January 2018

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Claudin-containing exosomes in the peripheral circulation of women with ovarian cancer

21 January 2018

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Claudins overexpression in ovarian cancer: potential targets for Clostridium Perfringens Enterotoxin (CPE) based diagnosis and therapy

21 January 2018

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Sialoglycoproteins and N-glycans from secreted exosomes of ovarian carcinoma cells

21 January 2018

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Characterization and proteomic analysis of ovarian cancer-derived exosomes

21 January 2018

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Ovarian cancer cell invasiveness is associated with discordant exosomal sequestration of Let-7 miRNA and miR-200

21 January 2018

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Exosomes from ovarian cancer cells induce adipose tissue-derived mesenchymal stem cells to acquire the physical and functional characteristics of tumor-supporting myofibroblasts

21 January 2018

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Inhibition of Hedgehog signaling antagonizes serous ovarian cancer growth in a primary xenograft model

21 January 2018

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MicroRNAs reprogram normal fibroblasts into cancer-associated fibroblasts in ovarian cancer

21 January 2018

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Cleaved caspase-3 and nuclear factor-kappaB p65 are prognostic factors in metastatic serous ovarian carcinoma

21 January 2018

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HOXB8 expression in ovarian serous carcinoma effusions is associated with shorter survival.

21 January 2018

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Class III β-tubulin expression in advanced-stage serous ovarian carcinoma effusions is associated with poor survival and primary chemoresistance

21 January 2018

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Prognostic significance of L1CAM in ovarian cancer and its role in constitutive NF-κB activation

21 January 2018

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Defining a prognostic marker panel for patients with ovarian serous carcinoma effusion

21 January 2018

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Acceptability of prophylactic salpingectomy with delayed oophorectomy as risk-reducing surgery among BRCA mutation carriers

21 January 2018

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Prophylactic bilateral salpingectomy as a prevention strategy in women at high-risk of ovarian cancer: a mini-review

21 January 2018

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Screening for ovarian cancer: U.S. Preventive Services Task Force reaffirmation recommendation statement

21 January 2018

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Assessing the risk of ovarian malignancy in asymptomatic women with abnormal CA 125 and transvaginal ultrasound scans in the prostate, lung, colorectal, and ovarian screening trial

21 January 2018

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Risks and benefits of screening asymptomatic women for ovarian cancer: a systematic review and meta-analysis

21 January 2018

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Assessment of symptomatic women for early diagnosis of ovarian cancer: results from the prospective DOvE pilot project

21 January 2018

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A 2-stage ovarian cancer screening strategy using the Risk of Ovarian Cancer Algorithm (ROCA) identifies early-stage incident cancers and demonstrates high positive predictive value

21 January 2018

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Targeting tyrosine-kinases in ovarian cancer

21 January 2018

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Folate and folate receptor alpha antagonists mechanism of action in ovarian cancer

21 January 2018

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The role of the tumor stroma in ovarian cancer

21 January 2018

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Breast cancer 1 (BRCA1) protein expression as a prognostic marker in sporadic epithelial ovarian carcinoma: an NCIC CTG OV.16 correlative study

21 January 2018

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21 January 2018

Identifiers

DOI

10.2217/WHE.14.37

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1 September 2017

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PubMed ID

25335543