Age-dependent changes on TGFβ1 Smad3 pathway modify the pattern of microglial cell activation (Q38260767)

1 September 2017

Age-dependent changes on TGFβ1 Smad3 pathway modify the pattern of microglial cell activation (English)

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1 September 2017

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6

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12 June 2020

author name string

Juan E Tichauer

1

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12 June 2020

Betsi Flores

2

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12 June 2020

Bernardita Soler

3

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12 June 2020

Laura Eugenín-von Bernhardi

4

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12 June 2020

Gigliola Ramírez

5

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12 June 2020

publication date

29 December 2013

1 reference

Brain, Behavior, and Immunity

1 September 2017

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12 June 2020

volume

37

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12 June 2020

page(s)

187-196

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describes a project that uses

12 June 2020

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3951654/fullTextXML

inferred from PubMed Central ID database lookup

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Microglia demonstrate age-dependent interaction with amyloid-β fibrils

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SMAD3 expression is regulated by mitogen-activated protein kinase kinase-1 in epithelial and smooth muscle cells

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Deficiency in neuronal TGF-beta signaling promotes neurodegeneration and Alzheimer's pathology

6 September 2017

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Association of a polymorphism of the transforming growth factor-beta1 gene with cerebral amyloid angiopathy

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Transforming growth factor-beta 1 inhibition of macrophage activation is mediated via Smad3.

6 September 2017

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Expression of scavenger receptors in glial cells. Comparing the adhesion of astrocytes and microglia from neonatal rats to surface-bound beta-amyloid

6 September 2017

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Sp1 and Smad transcription factors co-operate to mediate TGF-beta-dependent activation of amyloid-beta precursor protein gene transcription.

14 September 2017

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Transforming growth factor-β stimulates β amyloid uptake by microglia through Smad3-dependent mechanisms.

23 June 2018

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Proinflammatory stimuli are needed for induction of microglial cell-mediated AbetaPP_{244-C} and Abeta-neurotoxicity in hippocampal cultures.

31 August 2018

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31 August 2018

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31 August 2018

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31 August 2018

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31 August 2018

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31 August 2018

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31 August 2018

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31 August 2018

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31 August 2018

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31 August 2018

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31 August 2018

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31 August 2018

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Microglial cells internalize aggregates of the Alzheimer's disease amyloid beta-protein via a scavenger receptor.

31 August 2018

1 reference

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31 August 2018

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12 December 2020

Increased cerebrospinal fluid levels of transforming growth factor-beta1 in Alzheimer's disease

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12 December 2020

Modulation by astrocytes of microglial cell-mediated neuroinflammation: effect on the activation of microglial signaling pathways

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12 December 2020

Proliferating culture of aged microglia for the study of neurodegenerative diseases

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12 December 2020

TGF-β signaling through SMAD2/3 induces the quiescent microglial phenotype within the CNS environment

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12 December 2020

10.1016/J.BBI.2013.12.018

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24380849%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24380849%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24380849%20AND%20SRC:MED&resulttype=core&format=json