Multiple Myeloma Includes Phenotypically Defined Subsets of Clonotypic CD20+ B Cells that Persist During Treatment with Rituximab (Q38260684)

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12 February 2020

title

Multiple Myeloma Includes Phenotypically Defined Subsets of Clonotypic CD20+ B Cells that Persist During Treatment with Rituximab (English)

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12 February 2020

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Linda M Pilarski

1

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12 February 2020

Eva Baigorri

2

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12 February 2020

Michael J Mant

3

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12 February 2020

Patrick M Pilarski

4

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12 February 2020

Penelope Adamson

5

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12 February 2020

Heddy Zola

6

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12 February 2020

Andrew R Belch

7

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12 February 2020

publication date

27 March 2008

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Clinical medicine. Oncology

12 February 2020

published in

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12 February 2020

volume

2

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12 February 2020

page(s)

275-287

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Evolving role of monoclonal antibodies in the treatment of chronic lymphocytic leukemia

12 February 2020

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Intraclonal homogeneity of clonotypic immunoglobulin M and diversity of nonclinical post-switch isotypes in multiple myeloma: insights into the evolution of the myeloma clone

6 September 2017

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Severe deficiency of B lymphocytes in peripheral blood from multiple myeloma patients

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Abnormal function of B lymphocytes from peripheral blood of multiple myeloma patients. Lack of correlation between the number of cells potentially able to secrete immunoglobulin M and serum immunoglobulin M levels

6 September 2017

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Complement-induced cell death by rituximab depends on CD20 expression level and acts complementary to antibody-dependent cellular cytotoxicity

6 September 2017

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Ex vivo-activated human macrophages kill chronic lymphocytic leukemia cells in the presence of rituximab: mechanism of antibody-dependent cellular cytotoxicity and impact of human serum.

14 September 2017

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IMMUNOLOGICAL DEFICIENCY DISORDERS ASSOCIATED WITH CHRONIC LYMPHOCYTIC LEUKEMIA AND MULTIPLE MYELOMA.

14 September 2017

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Circulating clonotypic B cells in the biology of multiple myeloma: speculations on the origin of myeloma

14 September 2017

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Quantitation of circulating peripheral blood plasma cells and their relationship to disease activity in patients with multiple myeloma

28 September 2017

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Expression of IL-6 and IL-6 receptors by circulating clonotypic B cells in multiple myeloma: potential for autocrine and paracrine networks.

28 September 2017

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Muc-1 core protein is expressed on multiple myeloma cells and is induced by dexamethasone.

23 June 2018

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In multiple myeloma, clonotypic B lymphocytes are detectable among CD19+ peripheral blood cells expressing CD38, CD56, and monotypic Ig light chain

23 June 2018

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The mechanism of tumor cell clearance by rituximab in vivo in patients with B-cell chronic lymphocytic leukemia: evidence of caspase activation and apoptosis induction

23 June 2018

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Tumor cell expression of CD59 is associated with resistance to CD20 serotherapy in patients with B-cell malignancies.

31 August 2018

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A high frequency of circulating B cells share clonotypic Ig heavy-chain VDJ rearrangements with autologous bone marrow plasma cells in multiple myeloma, as measured by single-cell and in situ reverse transcriptase-polymerase chain reaction.

31 August 2018

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CD45 isoform transitions on multinegative human thymocytes differentiating in vitro mimic patterns predicted for selective events in vivo.

31 August 2018

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Evidence that the clonogenic cell in multiple myeloma originates from a pre-switched but somatically mutated B cell.

31 August 2018

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In multiple myeloma, circulating hyperdiploid B cells have clonotypic immunoglobulin heavy chain rearrangements and may mediate spread of disease

31 August 2018

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Deficient drug transporter function of bone marrow-localized and leukemic plasma cells in multiple myeloma

1 October 2018

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CD34+ cells in the blood of patients with multiple myeloma express CD19 and IgH mRNA and have patient-specific IgH VDJ gene rearrangements

1 October 2018

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Clonotypic myeloma cells able to xenograft myeloma to nonobese diabetic severe combined immunodeficient mice copurify with CD34 (+) hematopoietic progenitors

1 October 2018

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12 December 2020

Transition in CD45 isoform expression during differentiation of normal and abnormal B cells

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12 December 2020

Hyaluronan-dependent motility of B cells and leukemic plasma cells in blood, but not of bone marrow plasma cells, in multiple myeloma: alternate use of receptor for hyaluronan-mediated motility (RHAMM) and CD44

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12 December 2020

Selective expression of CD45 isoforms defines CALLA+ monoclonal B-lineage cells in peripheral blood from myeloma patients as late stage B cells

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12 December 2020

Myeloma progenitors in the blood of patients with aggressive or minimal disease: engraftment and self-renewal of primary human myeloma in the bone marrow of NOD SCID mice

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12 December 2020

Humoral immune deficiency in multiple myeloma patients due to compromised B-cell function

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12 December 2020

Circulating blood B cells in multiple myeloma: analysis and relationship to circulating clonal cells and clinical parameters in a cohort of patients entered on the Eastern Cooperative Oncology Group phase III E9486 clinical trial

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12 December 2020

Levels of circulating CD19+ cells in patients with multiple myeloma

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12 December 2020

Persistent preswitch clonotypic myeloma cells correlate with decreased survival: evidence for isotype switching within the myeloma clone

1 reference

12 December 2020

CD20-Directed Serotherapy in Patients With Multiple Myeloma: Biologic Considerations and Therapeutic Applications

1 reference

12 December 2020

CD20 levels determine the in vitro susceptibility to rituximab and complement of B-cell chronic lymphocytic leukemia: further regulation by CD55 and CD59

1 reference

12 December 2020

Rituximab: a review of its use in non-Hodgkin's lymphoma and chronic lymphocytic leukaemia

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12 December 2020

Leukemic B cells clonally identical to myeloma plasma cells are myelomagenic in NOD/SCID mice

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12 December 2020

Detection of myeloma cells in the peripheral blood by flow cytometry

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12 December 2020

CD20-directed antibody-mediated immunotherapy induces responses and facilitates hematologic recovery in patients with Waldenstrom's macroglobulinemia

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12 December 2020

Identifiers

DOI

10.4137/CMO.S615

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21892289%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

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12 February 2020

PubMed publication ID

21892289

1 reference