Unique binding behavior of the recently approved angiotensin II receptor blocker azilsartan compared with that of candesartan (Q38258427)

1 September 2017

Unique binding behavior of the recently approved angiotensin II receptor blocker azilsartan compared with that of candesartan (English)

1 reference

1 September 2017

1 reference

ChEBI release 2020-05-28

Shin-ichiro Miura

1

1 reference

1 September 2017

Atsutoshi Okabe

2

1 reference

1 September 2017

Yoshino Matsuo

3

1 reference

1 September 2017

Sadashiva S Karnik

4

1 reference

1 September 2017

Keijiro Saku

5

1 reference

1 September 2017

4 October 2012

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1 September 2017

Hypertension Research

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1 September 2017

36

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1 September 2017

2

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1 September 2017

134-139

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https://scigraph.springernature.com/pub.10.1038/hr.2012.147

1 September 2017

0 references

cites work

Comparison of the efficacy and safety of azilsartan with that of candesartan cilexetil in Japanese patients with grade I-II essential hypertension: a randomized, double-blind clinical study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951115

Review: angiotensin II type 1 receptor blockers: class effects versus molecular effects

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951115

Angiotensin receptor blockers in hypertension. New insights from Japan

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951115

Next generation multifunctional angiotensin receptor blockers

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951115

Differential bonding interactions of inverse agonists of angiotensin II type 1 receptor in stabilizing the inactive state

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951115

Antihypertensive activity of angiotensin II AT1 receptor antagonists: a systematic review of studies with 24 h ambulatory blood pressure monitoring

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951115

Novel procedure for modeling ligand/receptor induced fit effects.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951115

Structure-activity relationships of inverse agonists for G-protein-coupled receptors

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951115

Architecture of P2Y nucleotide receptors: structural comparison based on sequence analysis, mutagenesis, and homology modeling.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951115

Angiotensin receptor blockers: how important is selectivity?

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951115

High constitutive activity of native H3 receptors regulates histamine neurons in brain.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951115

International union of pharmacology. XXIII. The angiotensin II receptors

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951115

Angiotensin type 2 receptor mediates valsartan-induced hypotension in conscious rats

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951115

Amino acid substitution matrices from protein blocks

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951115

A small difference in the molecular structure of angiotensin II receptor blockers induces AT₁ receptor-dependent and -independent beneficial effects

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951115

Molecular and cellular effects of azilsartan: a new generation angiotensin II receptor blocker

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951115

Mechanism of constitutive activation of the AT1 receptor: influence of the size of the agonist switch binding residue Asn(111).

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951115

Binding of valsartan to mammalian angiotensin AT1 receptors

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951115

Antihypertensive, insulin-sensitising and renoprotective effects of a novel, potent and long-acting angiotensin II type 1 receptor blocker, azilsartan medoxomil, in rat and dog models.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951115

Comparison of the novel angiotensin II receptor blocker azilsartan medoxomil vs valsartan by ambulatory blood pressure monitoring

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951115

"Network leaning" as a mechanism of insurmountable antagonism of the angiotensin II type 1 receptor by non-peptide antagonists

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951115

The comparative effects of azilsartan medoxomil and olmesartan on ambulatory and clinic blood pressure

31 August 2018

1 reference

12 December 2020

Effects of the angiotensin receptor blocker azilsartan medoxomil versus olmesartan and valsartan on ambulatory and clinic blood pressure in patients with stages 1 and 2 hypertension

1 reference

12 December 2020

In vitro antagonistic properties of a new angiotensin type 1 receptor blocker, azilsartan, in receptor binding and function studies

1 reference

12 December 2020

Molecular mechanism underlying inverse agonist of angiotensin II type 1 receptor

1 reference

12 December 2020

Role of aromaticity of agonist switches of angiotensin II in the activation of the AT1 receptor

1 reference

12 December 2020

Inverse agonism and neutral antagonism at alpha(1a)- and alpha(1b)-adrenergic receptor subtypes

1 reference

12 December 2020

Tetrazole and carboxylate groups of angiotensin receptor antagonists bind to the same subsite by different mechanisms

1 reference

12 December 2020

Synthesis and angiotensin II receptor antagonistic activities of benzimidazole derivatives bearing acidic heterocycles as novel tetrazole bioisosteres

1 reference

12 December 2020

Identifiers

DOI

10.1038/HR.2012.147

1 reference

Dimensions Publication ID

1 September 2017

1029943190

0 references

Fatcat ID

release_uu7qiluuibdvzbxq4wmeu5iaxu

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/uu7qiluuibdvzbxq4wmeu5iaxu

24 November 2022

mapped directly with Wikidata item

1 reference

1 September 2017

1 reference