Cancer: pathological nuclear reprogramming? (Q38230318)

31 August 2017

Cancer: pathological nuclear reprogramming? (English)

1 reference

31 August 2017

Colin R Goding

1

0 references

author name string

Duanqing Pei

series ordinal

2

1 reference

31 August 2017

Xin Lu

series ordinal

3

1 reference

31 August 2017

language of work or name

English

0 references

publication date

17 July 2014

1 reference

31 August 2017

Nature Reviews Cancer

1 reference

31 August 2017

14

1 reference

31 August 2017

8

1 reference

31 August 2017

568-573

1 reference

https://scigraph.springernature.com/pub.10.1038/nrc3781

31 August 2017

0 references

cites work

Sexually mature individuals of Xenopus laevis from the transplantation of single somatic nuclei

1 reference

Lymphocytes of the ToadXenopus laevisHave the Gene Set for Promoting Tadpole Development

31 March 2020

1 reference

Embryonic germ cells induce epigenetic reprogramming of somatic nucleus in hybrid cells

31 March 2020

1 reference

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

31 March 2020

1 reference

Sequential expression of pluripotency markers during direct reprogramming of mouse somatic cells

31 March 2020

1 reference

The Polycomb complex PRC2 and its mark in life

31 March 2020

1 reference

Mechanisms and dynamics of heterochromatin formation during mammalian development: closed paths and open questions.

31 March 2020

1 reference

A decade of exploring the cancer epigenome - biological and translational implications

31 March 2020

1 reference

The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain

31 March 2020

1 reference

Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1

31 March 2020

1 reference

Vitamin C induces Tet-dependent DNA demethylation and a blastocyst-like state in ES cells

31 March 2020

1 reference

Ascorbic acid enhances Tet-mediated 5-methylcytosine oxidation and promotes DNA demethylation in mammals

31 March 2020

1 reference

Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA

31 March 2020

1 reference

Early-stage epigenetic modification during somatic cell reprogramming by Parp1 and Tet2

31 March 2020

1 reference

Replacement of Oct4 by Tet1 during iPSC induction reveals an important role of DNA methylation and hydroxymethylation in reprogramming.

31 March 2020

1 reference

Tet and TDG mediate DNA demethylation essential for mesenchymal-to-epithelial transition in somatic cell reprogramming.

31 March 2020

1 reference

Hallmarks of Cancer: The Next Generation

31 March 2020

1 reference

MYC on the path to cancer

31 March 2020

1 reference

Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts

31 March 2020

1 reference

c-Myc is dispensable for direct reprogramming of mouse fibroblasts.

31 March 2020

1 reference

Metabolic regulation of epigenetics

31 March 2020

1 reference

The nexus of chromatin regulation and intermediary metabolism.

31 March 2020

1 reference

Tipping the balance: Cdk2 enables Myc to suppress senescence

31 March 2020

1 reference

Multiple roles of p53-related pathways in somatic cell reprogramming and stem cell differentiation.

31 March 2020

1 reference

Cellular senescence and its effector programs

31 March 2020

1 reference

The p53-PUMA axis suppresses iPSC generation

31 March 2020

1 reference

Senescence impairs successful reprogramming to pluripotent stem cells

31 March 2020

1 reference

The Ink4/Arf locus is a barrier for iPS cell reprogramming

31 March 2020

1 reference

The polycomb protein Ezh2 impacts on induced pluripotent stem cell generation

31 March 2020

1 reference

A late transition in somatic cell reprogramming requires regulators distinct from the pluripotency network.

31 March 2020

1 reference

31 March 2020

Phases of reprogramming

1 reference

Functional genomics reveals a BMP-driven mesenchymal-to-epithelial transition in the initiation of somatic cell reprogramming

31 March 2020

1 reference

A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts

31 March 2020

1 reference

A molecular roadmap of reprogramming somatic cells into iPS cells

31 March 2020

1 reference

Sequential introduction of reprogramming factors reveals a time-sensitive requirement for individual factors and a sequential EMT-MET mechanism for optimal reprogramming.

31 March 2020

1 reference

The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1

31 March 2020

1 reference

Reprogramming in vivo produces teratomas and iPS cells with totipotency features.

31 March 2020

1 reference

Premature termination of reprogramming in vivo leads to cancer development through altered epigenetic regulation

31 March 2020

1 reference

Ectopic expression of Oct-4 blocks progenitor-cell differentiation and causes dysplasia in epithelial tissues

31 March 2020

1 reference

Exome sequencing identifies somatic mutations of DNA methyltransferase gene DNMT3A in acute monocytic leukemia

31 March 2020

1 reference

TET1, a member of a novel protein family, is fused to MLL in acute myeloid leukemia containing the t(10;11)(q22;q23).

31 March 2020

1 reference

Acquired mutations in TET2 are common in myelodysplastic syndromes

31 March 2020

1 reference

Mutation in TET2 in myeloid cancers

31 March 2020

1 reference

Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation

31 March 2020

1 reference

What a difference a hydroxyl makes: mutant IDH, (R)-2-hydroxyglutarate, and cancer

31 March 2020

1 reference

Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation

31 March 2020

1 reference

TET2 mutations in acute myeloid leukemia (AML): results from a comprehensive genetic and clinical analysis of the AML study group

31 March 2020

1 reference

An integrated genomic analysis of human glioblastoma multiforme

31 March 2020

1 reference

IDH1 and IDH2 mutations in gliomas

31 March 2020

1 reference

IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype

31 March 2020

1 reference

Induction of sarcomas by mutant IDH2

31 March 2020

1 reference

Tumor development is associated with decrease of TET gene expression and 5-methylcytosine hydroxylation

31 March 2020

1 reference

Loss of 5-hydroxymethylcytosine is accompanied with malignant cellular transformation

31 March 2020

1 reference

Nuclear exclusion of TET1 is associated with loss of 5-hydroxymethylcytosine in IDH1 wild-type gliomas

31 March 2020

1 reference

Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma

31 March 2020

1 reference

Cancer stem cells in solid tumours: accumulating evidence and unresolved questions

31 March 2020

1 reference

Cancer stem cells versus phenotype-switching in melanoma

31 March 2020

1 reference

Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state

31 March 2020

1 reference

Mitf is the key molecular switch between mouse or human melanoma initiating cells and their differentiated progeny.

31 March 2020

1 reference

Transcription factors interfering with dedifferentiation induce cell type-specific transcriptional profiles

31 March 2020

1 reference

Pluripotent stem cells induced from mouse somatic cells by small-molecule compounds

31 March 2020

1 reference

Generation of iPSCs from mouse fibroblasts with a single gene, Oct4, and small molecules.

31 March 2020

1 reference

Culture parameters for stable expansion, genetic modification and germline transmission of rat pluripotent stem cells

31 March 2020

1 reference

LCX, leukemia-associated protein with a CXXC domain, is fused to MLL in acute myeloid leukemia with trilineage dysplasia having t(10;11)(q22;q23).

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25030952

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NRC3781

1 reference

Dimensions Publication ID

31 August 2017

0 references

1 reference