Chronic neuroinflammation in Alzheimer's disease: new perspectives on animal models and promising candidate drugs (Q38229613)

31 August 2017

Chronic neuroinflammation in Alzheimer's disease: new perspectives on animal models and promising candidate drugs (English)

1 reference

31 August 2017

0 references

0 references

Janice R Aldrich-Wright

5

1 reference

31 August 2017

Erika Gyengesi

7

0 references

Alejandra Rangel

object named as

Alejandra Rangel

4

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author name string

Christopher Millington

1

1 reference

31 August 2017

Sandra Sonego

2

1 reference

31 August 2017

Niloo Karunaweera

3

1 reference

31 August 2017

Iain L Campbell

6

1 reference

31 August 2017

Gerald Münch

8

1 reference

31 August 2017

language of work or name

English

0 references

publication date

16 June 2014

1 reference

BioMed Research International

31 August 2017

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31 August 2017

2014

1 reference

31 August 2017

309129

1 reference

Creative Commons Attribution 3.0 Unported

31 August 2017

start time

1 January 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

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Advanced glycation endproducts and their receptor RAGE in Alzheimer's disease.

6 September 2017

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Mechanisms of tau-induced neurodegeneration

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Curcumin supplementation lowers TNF-alpha, IL-6, IL-8, and MCP-1 secretion in high glucose-treated cultured monocytes and blood levels of TNF-alpha, IL-6, MCP-1, glucose, and glycosylated hemoglobin in diabetic rats

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Microglia-mediated neurotoxicity: uncovering the molecular mechanisms

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse.

6 September 2017

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Beta-amyloid-induced glial expression of both pro- and anti-inflammatory cytokines in cerebral cortex of aged transgenic Tg2576 mice with Alzheimer plaque pathology

6 September 2017

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Local synaptic connections of basal forebrain neurons

6 September 2017

1 reference

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Influence of advanced glycation end-products and AGE-inhibitors on nucleation-dependent polymerization of beta-amyloid peptide

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083880

Progressive decline in avoidance learning paralleled by inflammatory neurodegeneration in transgenic mice expressing interleukin 6 in the brain

6 September 2017

1 reference

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Inhibition of tumor necrosis factor by curcumin, a phytochemical

6 September 2017

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Neurologic disease induced in transgenic mice by cerebral overexpression of interleukin 6

6 September 2017

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Amyloid deposition as the central event in the aetiology of Alzheimer's disease

6 September 2017

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A versatile high throughput screening system for the simultaneous identification of anti-inflammatory and neuroprotective compounds.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083880

The carbonyl scavengers aminoguanidine and tenilsetam protect against the neurotoxic effects of methylglyoxal

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083880

Anti-inflammatory mechanisms of apigenin: inhibition of cyclooxygenase-2 expression, adhesion of monocytes to human umbilical vein endothelial cells, and expression of cellular adhesion molecules

14 September 2017

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Apigenin inhibits the production of NO and PGE2 in microglia and inhibits neuronal cell death in a middle cerebral artery occlusion-induced focal ischemia mice model

14 September 2017

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Apigenin blocks lipopolysaccharide-induced lethality in vivo and proinflammatory cytokines expression by inactivating NF-kappaB through the suppression of p65 phosphorylation.

14 September 2017

1 reference

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Apigenin-induced cell cycle arrest is mediated by modulation of MAPK, PI3K-Akt, and loss of cyclin D1 associated retinoblastoma dephosphorylation in human prostate cancer cells

14 September 2017

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Methylglyoxal impairs glucose metabolism and leads to energy depletion in neuronal cells--protection by carbonyl scavengers

14 September 2017

1 reference

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Effect of apigenin, kaempferol and resveratrol on the expression of interleukin-1beta and tumor necrosis factor-alpha genes in J774.2 macrophages.

14 September 2017

1 reference

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The Chemopreventive Bioflavonoid Apigenin Modulates Signal Transduction Pathways in Keratinocyte and Colon Carcinoma Cell Lines

14 September 2017

1 reference

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Molecular dissection of the paired helical filament

14 September 2017

1 reference

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Receptor for advanced glycation end products plays a more important role in cellular survival than in neurite outgrowth during retinoic acid-induced differentiation of neuroblastoma cells

14 September 2017

1 reference

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Investigation into the involvement of phospholipases A(2) and MAP kinases in modulation of AA release and cell growth in A549 cells

28 September 2017

1 reference

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Cholinergic changes in the APP23 transgenic mouse model of cerebral amyloidosis.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083880

Selective loss of basal forebrain cholinergic neurons in APP770 transgenic mice

23 June 2018

1 reference

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Neurofibrillary degeneration and cell loss in the nucleus basalis in comparison to cortical Alzheimer pathology.

23 June 2018

1 reference

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Interleukin-6-associated inflammatory processes in Alzheimer's disease: new therapeutic options.

23 June 2018

1 reference

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Curcumin-loaded nanoparticles potently induce adult neurogenesis and reverse cognitive deficits in Alzheimer's disease model via canonical Wnt/β-catenin pathway

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083880

Cholinergic denervation exacerbates amyloid pathology and induces hippocampal atrophy in Tg2576 mice.

31 August 2018

1 reference

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Role of interleukin 6 and alpha-globulins in differentiating Alzheimer and vascular dementias.

31 August 2018

1 reference

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Clinical stabilisation in neurodegenerative diseases: clinical study in phase II

31 August 2018

1 reference

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Alzheimer's disease: Seeing the signs early

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083880

Inflammation and the redox-sensitive AGE-RAGE pathway as a therapeutic target in Alzheimer's disease

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083880

Impact of cognitive impairment on mild dementia patients and mild cognitive impairment patients and their informants.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083880

Methylglyoxal, glyoxal, and their detoxification in Alzheimer's disease

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083880

Age- and stage-dependent accumulation of advanced glycation end products in intracellular deposits in normal and Alzheimer's disease brains.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083880

Modulation of lipopolysaccharide-induced proinflammatory cytokine production in vitro and in vivo by the herbal constituents apigenin (chamomile), ginsenoside Rb(1) (ginseng) and parthenolide (feverfew).

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083880

Assessment of neuroinflammation and microglial activation in Alzheimer's disease with radiolabelled PK11195 and single photon emission computed tomography. A pilot study

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083880

Curcumin prevents alcohol-induced liver disease in rats by inhibiting the expression of NF-kappa B-dependent genes

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083880

Aberrant expression of NOS isoforms in Alzheimer's disease is structurally related to nitrotyrosine formation

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083880

Flavonoids increase the intracellular glutathione level by transactivation of the gamma-glutamylcysteine synthetase catalytical subunit promoter

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083880

Reduced hippocampal neurogenesis in adult transgenic mice with chronic astrocytic production of interleukin-6.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083880

Progressive loss of cortical acetylcholinesterase activity in association with cognitive decline in Alzheimer's disease: a positron emission tomography study.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083880

Suppression of inducible cyclooxygenase and inducible nitric oxide synthase by apigenin and related flavonoids in mouse macrophages.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083880

Free radicals in Alzheimer's disease.

31 August 2018

1 reference

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Structural and functional impact of the transgenic expression of cytokines in the CNS.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083880

[New hypothesis on etiopathogenesis of Alzheimer syndrome. Advanced glycation end products (AGEs)].

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083880

Amyloid-beta in Alzheimer Disease: The Null versus the Alternate Hypotheses

31 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1155%2F2014%2F309129

Curcumin Inhibits TLR2/4-NF-κB Signaling Pathway and Attenuates Brain Damage in Permanent Focal Cerebral Ischemia in Rats

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1155%2F2014%2F309129

Influence of advanced glycation end-products and AGE-inhibitors on nucleation-dependent polymerization of β-amyloid peptide

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1155%2F2014%2F309129

The cognition-enhancing drug tenilsetam is an inhibitor of protein crosslinking by advanced glycosylation

21 January 2018

1 reference

12 December 2020

Apigenin inhibits tumor necrosis factor-induced intercellular adhesion molecule-1 upregulation in vivo

1 reference

12 December 2020

Determination of tenilsetam in human plasma and urine by high-performance liquid chromatography

1 reference

12 December 2020

Effect of pseudophosphorylation and cross-linking by lipid peroxidation and advanced glycation end product precursors on tau aggregation and filament formation

1 reference

12 December 2020

Advanced glycation endproducts and the kidney

1 reference

12 December 2020

Advanced glycation endproducts in ageing and Alzheimer's disease

1 reference

12 December 2020

Transgenic mice and cytokine actions in the brain: bridging the gap between structural and functional neuropathology

1 reference

12 December 2020

Alzheimer's disease--synergistic effects of glucose deficit, oxidative stress and advanced glycation endproducts

1 reference

12 December 2020

Identifiers

DOI

10.1155/2014/309129

1 reference

31 August 2017

1 reference

31 August 2017

1 reference