Nitroxyl (HNO) for treatment of acute heart failure (Q38224809)

31 August 2017

Nitroxyl (HNO) for treatment of acute heart failure (English)

1 reference

Acute decompensated heart failure

31 August 2017

0 references

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24980211%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Carlo Gabriele Tocchetti

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24980211%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

author name string

Alessia Arcaro

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24980211%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

publication date

1 September 2014

1 reference

Current heart failure reports

31 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24980211%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

volume

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24980211%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

page(s)

227-235

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24980211%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24980211%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1007/s11897-014-0210-z

10 June 2020

exact match

0 references

cites work

Tackling heart failure in the twenty-first century

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

Examining nitroxyl in biological systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

The shy Angeli and his elusive creature: the HNO route to vasodilation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

Nitroxyl anion exerts redox-sensitive positive cardiac inotropy in vivo by calcitonin gene-related peptide signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

Positive inotropic and lusitropic effects of HNO/NO − in failing hearts: Independence from β-adrenergic signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

Nitroxyl (HNO): A novel approach for the acute treatment of heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

Playing with cardiac "redox switches": the "HNO way" to modulate cardiac function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

HNO enhances SERCA2a activity and cardiomyocyte function by promoting redox-dependent phospholamban oligomerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

Calcium release from the sarcoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

Cardiac excitation-contraction coupling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

Protein phosphorylation and signal transduction in cardiac thin filaments

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

Altered cardiac myocyte Ca regulation in heart failure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

Beta-adrenergic enhancement of sarcoplasmic reticulum calcium leak in cardiac myocytes is mediated by calcium/calmodulin-dependent protein kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

Role of oxidative stress in cardiac hypertrophy and remodeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

Nitric oxide/reactive oxygen species generation and nitroso/redox imbalance in heart failure: from molecular mechanisms to therapeutic implications.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

Changes in gene expression in the intact human heart. Downregulation of alpha-myosin heavy chain in hypertrophied, failing ventricular myocardium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

Mechanisms and models in heart failure: the biomechanical model and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

Role of inotropic agents in the treatment of heart failure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

Cardiac inotropes: current agents and future directions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

Targeting myocardial remodelling to develop novel therapies for heart failure: a position paper from the Working Group on Myocardial Function of the European Society of Cardiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

Mechanisms and use of calcium-sensitizing agents in the failing heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

Clinical trials update from the American Heart Association: REPAIR-AMI, ASTAMI, JELIS, MEGA, REVIVE-II, SURVIVE, and PROACTIVE.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

The effects of the cardiac myosin activator, omecamtiv mecarbil, on cardiac function in systolic heart failure: a double-blind, placebo-controlled, crossover, dose-ranging phase 2 trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

Cardiac myosin activation: a potential therapeutic approach for systolic heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

Hemodynamic, echocardiographic, and neurohormonal effects of istaroxime, a novel intravenous inotropic and lusitropic agent: a randomized controlled trial in patients hospitalized with heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

Calcium Upregulation by Percutaneous Administration of Gene Therapy in Cardiac Disease (CUPID): a phase 2 trial of intracoronary gene therapy of sarcoplasmic reticulum Ca2+-ATPase in patients with advanced heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

SERCA2a gene therapy in heart failure: an anti-arrhythmic positive inotrope.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

Comparison of the NO and HNO donating properties of diazeniumdiolates: primary amine adducts release HNO in Vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

Hydrolysis of Acyloxy Nitroso Compounds Yields Nitroxyl (HNO)

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

The effects of nitroxyl (HNO) on soluble guanylate cyclase activity: interactions at ferrous heme and cysteine thiols.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

Comparison of the reactivity of nitric oxide and nitroxyl with heme proteins. A chemical discussion of the differential biological effects of these redox related products of NOS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

Nitroxyl, redox switches, cardiac myofilaments, and heart failure: a prequel to novel therapeutics?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

Protein cysteine modifications: (1) medical chemistry for proteomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

NMR detection and study of hydrolysis of HNO-derived sulfinamides

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

Reactions of HNO with heme proteins: new routes to HNO-heme complexes and insight into physiological effects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

Intermolecular disulfide bond to modulate protein function as a redox-sensing switch

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

Redox regulation of cardiac calcium channels and transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

Disulfides as redox switches: from molecular mechanisms to functional significance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

Cardiac oxidative stress in acute and chronic isoproterenol-infused rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

Functional role of hyperreactive sulfhydryl moieties within the ryanodine receptor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

Evidence of myofibrillar protein oxidation induced by postischemic reperfusion in isolated rat hearts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

Oxidative modification of tropomyosin and myocardial dysfunction following coronary microembolization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

Redox modification of ryanodine receptors contributes to sarcoplasmic reticulum Ca2+ leak in chronic heart failure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

Oxidation of myofilament protein sulfhydryl groups reduces the contractile force and its Ca2+ sensitivity in human cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

The L-type Ca(2+) channel as a potential mediator of pathology during alterations in cellular redox state

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

Nitroxyl improves cellular heart function by directly enhancing cardiac sarcoplasmic reticulum Ca2+ cycling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

Nitroxyl enhances myocyte Ca2+ transients by exclusively targeting SR Ca2+-cycling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

Nitroxyl triggers Ca2+ release from skeletal and cardiac sarcoplasmic reticulum by oxidizing ryanodine receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

Nitroxyl activates SERCA in cardiac myocytes via glutathiolation of cysteine 674.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

Phospholamban thiols play a central role in activation of the cardiac muscle sarcoplasmic reticulum calcium pump by nitroxyl.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

Hydrogen sulfide interacts with nitric oxide in the heart: possible involvement of nitroxyl

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

The new HNO donor, 1-nitrosocyclohexyl acetate, increases contractile force in normal and β-adrenergically desensitized ventricular myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

Oxidative and nitrosative stress in the maintenance of myocardial function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

Regulation of the mammalian heart function by nitric oxide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

The pharmacology of nitroxyl (HNO) and its therapeutic potential: not just the Janus face of NO

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

Calcitonin gene-related peptide in vivo positive inotropy is attributable to regional sympatho-stimulation and is blunted in congestive heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

A role for nitroxyl (HNO) as an endothelium-derived relaxing and hyperpolarizing factor in resistance arteries.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

Isopropylamine NONOate (IPA/NO) moderates neointimal hyperplasia following vascular injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

Nitroxyl (HNO) as a vasoprotective signaling molecule.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

Redox signaling in cardiac physiology and pathology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

Vasorelaxant and antiaggregatory actions of the nitroxyl donor isopropylamine NONOate are maintained in hypercholesterolemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

New positive inotropic agents in the treatment of congestive heart failure. Mechanisms of action and recent clinical developments. 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

New positive inotropic agents in the treatment of congestive heart failure. Mechanisms of action and recent clinical developments. 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

Role of carvedilol controlled-release in cardiovascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

Nitroxyl affords thiol-sensitive myocardial protective effects akin to early preconditioning.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

Redox regulation of the mitochondrial K(ATP) channel in cardioprotection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

Neurotoxicity of nitroxyl: insights into HNO and NO biochemical imbalance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

Nitroxyl exacerbates ischemic cerebral injury and oxidative neurotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11897-014-0210-Z

Ranolazine protects from doxorubicin-induced oxidative stress and cardiac dysfunction.

21 January 2018

1 reference

12 December 2020

Regulation of contraction in striated muscle

1 reference

12 December 2020

Mechanism of aerobic decomposition of Angeli's salt (sodium trioxodinitrate) at physiological pH

1 reference

12 December 2020

Nitroxyl increases force development in rat cardiac muscle

1 reference

12 December 2020

Inotropes and inodilators for acute heart failure: sarcomere active drugs in focus

1 reference

12 December 2020

Reactive oxygen species and excitation-contraction coupling in the context of cardiac pathology

1 reference

12 December 2020

Phosphorylation of phospholamban by cAMP-dependent protein kinase enhances interactions between Ca-ATPase polypeptide chains in cardiac sarcoplasmic reticulum membranes

1 reference

12 December 2020

Modulation of cardiac contractility by the phospholamban/SERCA2a regulatome

1 reference

12 December 2020

The nitroxyl anion (HNO) is a potent dilator of rat coronary vasculature

1 reference

12 December 2020

Development of N-substituted hydroxylamines as efficient nitroxyl (HNO) donors

1 reference

12 December 2020

Effect of nitroxyl on human platelets function

1 reference

12 December 2020

Regulation of Ryanodine Receptor Ion Channels Through Posttranslational Modifications

1 reference

12 December 2020

Peroxynitrite and myocardial contractility: in vivo versus in vitro effects

1 reference

12 December 2020

Nitroxyl-mediated disulfide bond formation between cardiac myofilament cysteines enhances contractile function.

1 reference

12 December 2020

The pharmacological activity of nitroxyl: a potent vasodilator with activity similar to nitric oxide and/or endothelium-derived relaxing factor

1 reference

12 December 2020