The multivalent effect in glycosidase inhibition: a new, rapidly emerging topic in glycoscience (Q38210134)

31 August 2017

The multivalent effect in glycosidase inhibition: a new, rapidly emerging topic in glycoscience (English)

1 reference

31 August 2017

Philippe Compain

1

1 reference

PubMed ID

24807298

31 August 2017

Anne Bodlenner

series ordinal

2

1 reference

31 August 2017

7 May 2014

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31 August 2017

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31 August 2017

15

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31 August 2017

9

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31 August 2017

1239-1251

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Influenza neuraminidase inhibitors possessing a novel hydrophobic interaction in the enzyme active site: design, synthesis, and structural analysis of carbocyclic sialic acid analogues with potent anti-influenza activity

31 August 2017

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Use of the selective oral neuraminidase inhibitor oseltamivir to prevent influenza

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Importance of glycosidases in mammalian glycoprotein biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Recent structural insights into the expanding world of carbohydrate-active enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

21 January 2018

Glycosidase mechanisms

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

21 January 2018

Glycosidase mechanisms

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Mechanistic insights into glycosidase chemistry

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Recent developments of transition-state analogue glycosidase inhibitors of non-natural product origin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Glycosidase inhibitors: update and perspectives on practical use.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Glycosidase inhibition: assessing mimicry of the transition state

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Covalent inhibitors of glycosidases and their applications in biochemistry and biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Glycosidase inhibitors as potential HIV entry inhibitors?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Glycosylation pathways as drug targets for cancer: glycosidase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Therapeutic applications of sugar-mimicking glycosidase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Inhibitors of Carbohydrate-Processing Enzymes: Design and Synthesis of Sugar-Shaped Heterocycles

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Inhibitors against glycosidases as medicines

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Imino sugars and glycosyl hydrolases: historical context, current aspects, emerging trends

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Recent Insights into Inhibition, Structure, and Mechanism of Configuration-Retaining Glycosidases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Synthesis and deconvolution of the first combinatorial library of glycosidase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Insights in the rational design of synthetic multivalent glycoconjugates as lectin ligands.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Maximising multivalency effects in protein-carbohydrate interactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Glycomimetics and glycodendrimers as high affinity microbial anti-adhesins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Design and creativity in synthesis of multivalent neoglycoconjugates

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Multivalent ligand presentation as a central concept to study intricate carbohydrate-protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Cyclodextrin-based multivalent glycodisplays: covalent and supramolecular conjugates to assess carbohydrate-protein interactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Multivalent glycoconjugate syntheses and applications using aromatic scaffolds

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Carbohydrate mimics and lectins: a source of new drugs and therapeutic opportunities.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

The cluster glycoside effect

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Lectins: tools for the molecular understanding of the glycocode.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Multivalent lectin-carbohydrate interactions energetics and mechanisms of binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Carbohydrate-protein interactions: a 3D view by NMR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Shiga-like toxins are neutralized by tailored multivalent carbohydrate ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Influencing Receptor−Ligand Binding Mechanisms with Multivalent Ligand Architecture

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Synthetic multivalent ligands in the exploration of cell-surface interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Entropic Contributions to Rate Accelerations in Enzymic and Intramolecular Reactions and the Chelate Effect

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Bridging lectin binding sites by multivalent carbohydrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Peptidotriazoles on solid phase: [1,2,3]-triazoles by regiospecific copper(i)-catalyzed 1,3-dipolar cycloadditions of terminal alkynes to azides

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Multivalent iminosugars to modulate affinity and selectivity for glycosidases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Glycosidase inhibition with fullerene iminosugar balls: a dramatic multivalent effect.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Topological effects and binding modes operating with multivalent iminosugar-based glycoclusters and mannosidases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

A systematic investigation of iminosugar click clusters as pharmacological chaperones for the treatment of Gaucher disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Rescue of functional CFTR channels in cystic fibrosis: a dramatic multivalent effect using iminosugar cluster-based correctors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

The multivalent effect in glycosidase inhibition: probing the influence of valency, peripheral ligand structure, and topology with cyclodextrin-based iminosugar click clusters.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Fullerene-sp2-iminosugar balls as multimodal ligands for lectins and glycosidases: a mechanistic hypothesis for the inhibitory multivalent effect.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Low-generation dendrimers with a calixarene core and based on a chiral C(2)-symmetric pyrrolidine as iminosugar mimics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Synthetic multivalent ligands as probes of signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Carbohydrate-functionalized dendrimers to investigate the predictable tunability of multivalent interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Synthesis of N-, S-, and C-glycoside castanospermine analogues with selective neutral alpha-glucosidase inhibitory activity as antitumour agents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

sp2-Iminosugar O-, S-, and N-glycosides as conformational mimics of α-linked disaccharides; implications for glycosidase inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Macromolecular recognition: effect of multivalency in the inhibition of binding of yeast mannan to concanavalin A and pea lectins by mannosylated dendrimers

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

The Carbohydrate-Active EnZymes database (CAZy): an expert resource for Glycogenomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Structure of Golgi alpha-mannosidase II: a target for inhibition of growth and metastasis of cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Insights into the mechanism of Drosophila melanogaster Golgi alpha-mannosidase II through the structural analysis of covalent reaction intermediates

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

The structure of bovine lysosomal alpha-mannosidase suggests a novel mechanism for low-pH activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Golgi -mannosidase II cleaves two sugars sequentially in the same catalytic site

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Thermodynamic studies of lectin-carbohydrate interactions by isothermal titration calorimetry

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Thermodynamic binding studies of lectins from the diocleinae subtribe to deoxy analogs of the core trimannoside of asparagine-linked oligosaccharides

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Thermodynamic analysis of biomolecular interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Potent and long-acting dimeric inhibitors of influenza virus neuraminidase are effective at a once-weekly dosing regimen

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Dimeric zanamivir conjugates with various linking groups are potent, long-lasting inhibitors of influenza neuraminidase including H5N1 avian influenza.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Highly potent and long-acting trimeric and tetrameric inhibitors of influenza virus neuraminidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Synthesis and anti-influenza evaluation of polyvalent sialidase inhibitors bearing 4-guanidino-Neu5Ac2en derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Attaching zanamivir to a polymer markedly enhances its activity against drug-resistant strains of influenza a virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Polymer-attached zanamivir inhibits synergistically both early and late stages of influenza virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Synthesis and anti-influenza virus activity of 7-O-alkylated derivatives related to zanamivir

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Synergistic effect of zanamivir-porphyrin conjugates on inhibition of neuraminidase and inactivation of influenza virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

A contradictory treatment for lysosomal storage disorders: inhibitors enhance mutant enzyme activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

What are pharmacological chaperones and why are they interesting?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Treating lysosomal storage diseases with pharmacological chaperones: from concept to clinics

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Pharmacological chaperone therapy for Gaucher disease: a patent review.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Pharmacological chaperones as therapeutics for lysosomal storage diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

A counterintuitive approach to treat enzyme deficiencies: use of enzyme inhibitors for restoring mutant enzyme activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Chemical chaperones increase the cellular activity of N370S beta -glucosidase: a therapeutic strategy for Gaucher disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Phosphorylation-regulated CI− channel in CHO cells stably expressing the cystic fibrosis gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Pharmacological therapy for cystic fibrosis: from bench to bedside

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Correctors of the basic trafficking defect of the mutant F508del-CFTR that causes cystic fibrosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Rescue of functional delF508-CFTR channels in cystic fibrosis epithelial cells by the alpha-glucosidase inhibitor miglustat

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

A cystic fibrosis respiratory epithelial cell chronically treated by miglustat acquires a non-cystic fibrosis-like phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Compounds that correct F508del-CFTR trafficking can also correct other protein trafficking diseases: an in vitro study using cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Glycoside and peptide clustering around the octasilsesquioxane scaffold via photoinduced free-radical thiol–ene coupling. The observation of a striking glycoside cluster effect

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

Thiyl Glycosylation of Propargylated Octasilsesquioxane: Synthesis and Lectin-Binding Properties of Densely Glycosylated Clusters on a Cubic Platform

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201402026

21 January 2018

Identifiers

DOI

10.1002/CBIC.201402026

1 reference

release_zerohwsr6rbwfjqpjecv6ystdy

31 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/zerohwsr6rbwfjqpjecv6ystdy

mapped directly with Wikidata item

24 November 2022

based on heuristic

PubMed ID

24807298

1 reference

PubMed ID

24807298