Genomic insights into tuberculosis (Q38198853)

30 August 2017

Genomic insights into tuberculosis (English)

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30 August 2017

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James E Galagan

1

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30 August 2017

25 March 2014

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30 August 2017

Nature Reviews Genetics

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30 August 2017

15

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30 August 2017

5

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30 August 2017

307-320

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https://scigraph.springernature.com/pub.10.1038/nrg3664

30 August 2017

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cites work

Mycobacterium tuberculosis: here today, and here tomorrow

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Who puts the tubercle in tuberculosis?

21 January 2018

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How can immunology contribute to the control of tuberculosis?

21 January 2018

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Mechanisms of latency in Mycobacterium tuberculosis

21 January 2018

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Is Mycobacterium tuberculosis 15,000 years old?

21 January 2018

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Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence

21 January 2018

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Comparative genomics of BCG vaccines by whole-genome DNA microarray

21 January 2018

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Identification of variable regions in the genomes of tubercle bacilli using bacterial artificial chromosome arrays

21 January 2018

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A new evolutionary scenario for the Mycobacterium tuberculosis complex

21 January 2018

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The origin and evolution of Mycobacterium tuberculosis

21 January 2018

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A novel pathogenic taxon of the Mycobacterium tuberculosis complex, Canetti: characterization of an exceptional isolate from Africa

21 January 2018

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Clinical characteristics of the smooth tubercle bacilli 'Mycobacterium canettii' infection suggest the existence of an environmental reservoir

21 January 2018

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Molecular characteristics of "Mycobacterium canettii" the smooth Mycobacterium tuberculosis bacilli

21 January 2018

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Ancient origin and gene mosaicism of the progenitor of Mycobacterium tuberculosis

21 January 2018

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Genomic analysis of smooth tubercle bacilli provides insights into ancestry and pathoadaptation of Mycobacterium tuberculosis

21 January 2018

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Inter- and intra-subtype genotypic differences that differentiate Mycobacterium avium subspecies paratuberculosis strains

21 January 2018

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Mycobacterium avium in the postgenomic era.

21 January 2018

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Mycobacterium avium subsp. paratuberculosis and M. avium subsp. avium are independently evolved pathogenic clones of a much broader group of M. avium organisms

21 January 2018

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Restricted structural gene polymorphism in the Mycobacterium tuberculosis complex indicates evolutionarily recent global dissemination

21 January 2018

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Human T cell epitopes of Mycobacterium tuberculosis are evolutionarily hyperconserved

21 January 2018

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Out-of-Africa migration and Neolithic coexpansion of Mycobacterium tuberculosis with modern humans

21 January 2018

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Does M. tuberculosis genomic diversity explain disease diversity?

21 January 2018

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Origin, spread and demography of the Mycobacterium tuberculosis complex

21 January 2018

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Mycobacterium tuberculosis complex genetic diversity: mining the fourth international spoligotyping database (SpolDB4) for classification, population genetics and epidemiology

21 January 2018

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Molecular epidemiology of tuberculosis: current insights

21 January 2018

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High functional diversity in Mycobacterium tuberculosis driven by genetic drift and human demography

21 January 2018

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Genomic deletions suggest a phylogeny for the Mycobacterium tuberculosis complex

21 January 2018

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Global phylogeography of Mycobacterium tuberculosis and implications for tuberculosis product development.

21 January 2018

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Variable host-pathogen compatibility in Mycobacterium tuberculosis

21 January 2018

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Mycobacterium du jour: what's on tomorrow's menu?

21 January 2018

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Mycobacterial lineages causing pulmonary and extrapulmonary tuberculosis, Ethiopia.

21 January 2018

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The complete genome sequence of Mycobacterium bovis

21 January 2018

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Characterization of Mycobacterium caprae isolates from Europe by mycobacterial interspersed repetitive unit genotyping

21 January 2018

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Tuberculosis in seals caused by a novel member of the Mycobacterium tuberculosis complex: Mycobacterium pinnipedii sp. nov

21 January 2018

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Host-pathogen coevolution in human tuberculosis

21 January 2018

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The role of selection in shaping diversity of natural M. tuberculosis populations

21 January 2018

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Novel Mycobacterium tuberculosis complex isolate from a wild chimpanzee

21 January 2018

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Tuberculosis in imported hyrax (Procavia capensis) caused by an unusual variant belonging to the Mycobacterium tuberculosis complex

21 January 2018

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Novel Mycobacterium tuberculosis complex pathogen, M. mungi

21 January 2018

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Totally drug-resistant tuberculosis (TDR-TB) in India: every dark cloud has a silver lining

21 January 2018

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Emergence and spread of extensively and totally drug-resistant tuberculosis, South Africa

21 January 2018

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Emergence of new forms of totally drug-resistant tuberculosis bacilli: super extensively drug-resistant tuberculosis or totally drug-resistant strains in iran.

21 January 2018

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Bacterial gene amplification: implications for the evolution of antibiotic resistance

21 January 2018

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Lateral gene transfer and the nature of bacterial innovation

21 January 2018

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Lateral Gene Transfer and the Origins of Prokaryotic Groups

21 January 2018

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Dynamics of genome rearrangement in bacterial populations

21 January 2018

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Fatty acid biosynthesis in Mycobacterium tuberculosis: lateral gene transfer, adaptive evolution, and gene duplication

21 January 2018

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Horizontally acquired genomic islands in the tubercle bacilli

21 January 2018

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Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis

21 January 2018

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Linkage disequilibrium between minisatellite loci supports clonal evolution of Mycobacterium tuberculosis in a high tuberculosis incidence area

21 January 2018

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Stable association between strains of Mycobacterium tuberculosis and their human host populations

21 January 2018

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After the bottleneck: Genome-wide diversification of the Mycobacterium tuberculosis complex by mutation, recombination, and natural selection

21 January 2018

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Functional and evolutionary genomics of Mycobacterium tuberculosis: insights from genomic deletions in 100 strains

21 January 2018

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Comparison of Mycobacterium tuberculosis genomes reveals frequent deletions in a 20 kb variable region in clinical isolates

21 January 2018

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IS6110-mediated deletion polymorphism in isogenic strains of Mycobacterium tuberculosis

21 January 2018

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IS 6110 -Mediated Deletion Polymorphism in the Direct Repeat Region of Clinical Isolates of Mycobacterium tuberculosis

21 January 2018

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Insertion and deletion events that define the pathogen Mycobacterium avium subsp. paratuberculosis

21 January 2018

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Massive gene duplication event among clinical isolates of the Mycobacterium tuberculosis W/Beijing family

21 January 2018

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Independent large scale duplications in multiple M. tuberculosis lineages overlapping the same genomic region

21 January 2018

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Spontaneous tandem amplification and deletion of the shiga toxin operon in Shigella dysenteriae 1.

21 January 2018

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Use of whole genome sequencing to estimate the mutation rate of Mycobacterium tuberculosis during latent infection

21 January 2018

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Mycobacterium tuberculosis mutation rate estimates from different lineages predict substantial differences in the emergence of drug-resistant tuberculosis

21 January 2018

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Mutation rate and the emergence of drug resistance in Mycobacterium tuberculosis.

21 January 2018

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A replication clock for Mycobacterium tuberculosis

21 January 2018

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Replication dynamics of Mycobacterium tuberculosis in chronically infected mice

21 January 2018

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Microbial persistence and the road to drug resistance

21 January 2018

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Sublethal antibiotic treatment leads to multidrug resistance via radical-induced mutagenesis

21 January 2018

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Role of reactive oxygen species in antibiotic action and resistance.

21 January 2018

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Genome analysis of multi- and extensively-drug-resistant tuberculosis from KwaZulu-Natal, South Africa

21 January 2018

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The non-clonality of drug resistance in Beijing-genotype isolates of Mycobacterium tuberculosis from the Western Cape of South Africa

21 January 2018

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Dynamics of antibiotic resistant Mycobacterium tuberculosis during long-term infection and antibiotic treatment

21 January 2018

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Microevolution of extensively drug-resistant tuberculosis in Russia

21 January 2018

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Dynamic population changes in Mycobacterium tuberculosis during acquisition and fixation of drug resistance in patients

21 January 2018

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Tuberculosis drug resistance: a global threat

21 January 2018

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Induction and inhibition of ciprofloxacin resistance-conferring mutations in hypermutator bacteria

21 January 2018

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DnaE2 polymerase contributes to in vivo survival and the emergence of drug resistance in Mycobacterium tuberculosis

21 January 2018

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Drug-resistant tuberculosis, clinical virulence, and the dominance of the Beijing strain family in Russia

21 January 2018

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Phylogeny of Mycobacterium tuberculosis Beijing strains constructed from polymorphisms in genes involved in DNA replication, recombination and repair

21 January 2018

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The heterogeneous evolution of multidrug-resistant Mycobacterium tuberculosis

21 January 2018

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The competitive cost of antibiotic resistance in Mycobacterium tuberculosis

21 January 2018

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Comparison of fitness of two isolates of Mycobacterium tuberculosis, one of which had developed multi-drug resistance during the course of treatment.

21 January 2018

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Effect of katG mutations on the virulence of Mycobacterium tuberculosis and the implication for transmission in humans.

21 January 2018

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Fitness cost of chromosomal drug resistance-conferring mutations

21 January 2018

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Fitness of antibiotic-resistant microorganisms and compensatory mutations.

21 January 2018

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Whole-genome sequencing of rifampicin-resistant Mycobacterium tuberculosis strains identifies compensatory mutations in RNA polymerase genes.

21 January 2018

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Putative compensatory mutations in the rpoC gene of rifampin-resistant Mycobacterium tuberculosis are associated with ongoing transmission

21 January 2018

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The Mycobacterium tuberculosis regulatory network and hypoxia

21 January 2018

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Genome-wide profiles of STAT1 DNA association using chromatin immunoprecipitation and massively parallel sequencing

21 January 2018

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Genome-wide maps of chromatin state in pluripotent and lineage-committed cells

21 January 2018

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Genome-wide mapping of in vivo protein-DNA interactions

21 January 2018

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Insights from genomic profiling of transcription factors

21 January 2018

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Protein networks in disease

21 January 2018

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Network motifs: theory and experimental approaches

21 January 2018

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Functional roles of pulsing in genetic circuits

21 January 2018

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Microfluidic devices for measuring gene network dynamics in single cells

21 January 2018

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Impulse control: temporal dynamics in gene transcription

21 January 2018

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Mycobacterium tuberculosis WhiB3 maintains redox homeostasis by regulating virulence lipid anabolism to modulate macrophage response

21 January 2018

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Transcriptional Adaptation of Mycobacterium tuberculosis within Macrophages: Insights into the Phagosomal Environment

21 January 2018

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Mycobacterium tuberculosis and the environment within the phagosome

21 January 2018

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Cholesterol metabolism increases the metabolic pool of propionate in Mycobacterium tuberculosis.

21 January 2018

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Cholesterol utilization in mycobacteria is controlled by two TetR-type transcriptional regulators: kstR and kstR2

21 January 2018

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A highly conserved transcriptional repressor controls a large regulon involved in lipid degradation in Mycobacterium smegmatis and Mycobacterium tuberculosis

21 January 2018

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A thiolase of Mycobacterium tuberculosis is required for virulence and production of androstenedione and androstadienedione from cholesterol

21 January 2018

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Characterization of the KstR-dependent promoter of the gene for the first step of the cholesterol degradative pathway in Mycobacterium smegmatis

21 January 2018

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Mycobacterium tuberculosis isocitrate lyases 1 and 2 are jointly required for in vivo growth and virulence

21 January 2018

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Mycobacterium tuberculosis uses host triacylglycerol to accumulate lipid droplets and acquires a dormancy-like phenotype in lipid-loaded macrophages

21 January 2018

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Triacylglycerol utilization is required for regrowth of in vitro hypoxic nonreplicating Mycobacterium bovis bacillus Calmette-Guerin

21 January 2018

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Foamy macrophages from tuberculous patients' granulomas constitute a nutrient-rich reservoir for M. tuberculosis persistence

21 January 2018

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Foamy macrophages and the progression of the human tuberculosis granuloma

21 January 2018

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Mycobacterium tuberculosis WhiB3 responds to O2 and nitric oxide via its [4Fe-4S] cluster and is essential for nutrient starvation survival

21 January 2018

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The evolutionary pressures that have molded Mycobacterium tuberculosis into an infectious adjuvant

21 January 2018

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Mycobacterium tuberculosis and the intimate discourse of a chronic infection

21 January 2018

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Mycobacterium and the coat of many lipids

21 January 2018

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Mycobacterium tuberculosis wears what it eats

21 January 2018

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A role for systems epidemiology in tuberculosis research

21 January 2018

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Tuberculosis and HIV co-infection

21 January 2018

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Tuberculosis and diabetes mellitus: convergence of two epidemics

21 January 2018

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Old Testament biblical references to tuberculosis

21 January 2018

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Tuberculosis: from prehistory to Robert Koch, as revealed by ancient DNA.

21 January 2018

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Genotype of a historic strain of Mycobacterium tuberculosis

21 January 2018

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Molecular analysis of skeletal tuberculosis in an ancient Egyptian population.

21 January 2018

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Molecular study on human tuberculosis in three geographically distinct and time delineated populations from ancient Egypt

21 January 2018

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Characterization of Mycobacterium tuberculosis complex DNAs from Egyptian mummies by spoligotyping

21 January 2018

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Rib lesions in skeletons from early neolithic sites in Central Germany: on the trail of tuberculosis at the onset of agriculture

21 January 2018

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Evidence of spinal tuberculosis at the beginning of the fourth millennium BC from Arene Candide cave (Liguria, Italy).

21 January 2018

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Outbreak of tuberculosis in a 2000-year-old Chinese population

21 January 2018

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Detection and molecular characterization of 9,000-year-old Mycobacterium tuberculosis from a Neolithic settlement in the Eastern Mediterranean

21 January 2018

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Identification of Mycobacterium tuberculosis DNA in a pre-Columbian Peruvian mummy

21 January 2018

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Pre-Columbian tuberculosis in northern Chile: molecular and skeletal evidence

21 January 2018

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The re-emergence of tuberculosis: what have we learnt from molecular epidemiology?

21 January 2018

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Spoligotyping and Mycobacterium tuberculosis

21 January 2018

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Comparison between spoligotyping and IS6110 restriction fragment length polymorphisms in molecular genotyping analysis of Mycobacterium tuberculosis strains

21 January 2018

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CRISPR Provides Acquired Resistance Against Viruses in Prokaryotes

21 January 2018

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CRISPR interference limits horizontal gene transfer in staphylococci by targeting DNA

21 January 2018

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DNA fingerprinting of Mycobacterium tuberculosis: from phage typing to whole-genome sequencing.

21 January 2018

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Characterization of a Mycobacterium tuberculosis insertion sequence belonging to the IS3 family

21 January 2018

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IS6110, a Mycobacterium tuberculosis complex-specific insertion sequence, is also present in the genome of Mycobacterium smegmatis, suggestive of lateral gene transfer among mycobacterial species

21 January 2018

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Proposal for standardization of optimized mycobacterial interspersed repetitive unit-variable-number tandem repeat typing of Mycobacterium tuberculosis

21 January 2018

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Multispacer sequence typing for Mycobacterium tuberculosis genotyping

21 January 2018

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ALLPATHS 2: small genomes assembled accurately and with high continuity from short paired reads

21 January 2018

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ALLPATHS: de novo assembly of whole-genome shotgun microreads

21 January 2018

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Consensus generation and variant detection by Celera Assembler

21 January 2018

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BIGrat: a repeat resolver for pyrosequencing-based re-sequencing with Newbler

21 January 2018

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A tale of three next generation sequencing platforms: comparison of Ion Torrent, Pacific Biosciences and Illumina MiSeq sequencers

21 January 2018

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A hybrid approach for the automated finishing of bacterial genomes

21 January 2018

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Reducing assembly complexity of microbial genomes with single-molecule sequencing

21 January 2018

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Whole-genome sequencing to delineate Mycobacterium tuberculosis outbreaks: a retrospective observational study

21 January 2018

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Whole-genome sequencing and social-network analysis of a tuberculosis outbreak

21 January 2018

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Whole-genome sequencing to establish relapse or re-infection with Mycobacterium tuberculosis: a retrospective observational study

21 January 2018

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Did ice-age bovids spread tuberculosis?

21 January 2018

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Hyperdisease in the late Pleistocene: validation of an early 20th century hypothesis

21 January 2018

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The rise and fall of the Mycobacterium tuberculosis genome

21 January 2018

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Contribution of horizontally acquired genomic islands to the evolution of the tubercle bacilli

31 March 2020

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The surprising diversity of Mycobacterium tuberculosis: change you can believe in

31 March 2020

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Physiological cost of rifampin resistance induced in vitro in Mycobacterium tuberculosis.

31 March 2020

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Topological and causal structure of the yeast transcriptional regulatory network

31 March 2020

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Dynamic persistence of antibiotic-stressed mycobacteria

31 March 2020

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Identification of Mycobacterium DNA in an Egyptian Pott's disease of 5400 years old

31 March 2020

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Paleopathology of human tuberculosis and the potential role of climate

31 March 2020

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Tuberculosis on the north coast of Peru: skeletal and molecular paleopathology of late pre-Hispanic and postcontact mycobacterial disease

31 March 2020

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The history of tuberculosis as a global epidemic

31 March 2020

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12 December 2020

Genome plasticity: insertion sequence elements, transposons and integrons, and DNA rearrangement

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12 December 2020

Imported extensively drug-resistant Mycobacterium tuberculosis Beijing genotype, Marseilles, France, 2011

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12 December 2020

General medicine in Atharvaveda with special reference to Yaksma (consumption/tuberculosis).

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12 December 2020

The granuloma in tuberculosis: dynamics of a host-pathogen collusion

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12 December 2020

The Beijing genotype is a major cause of drug-resistant tuberculosis in Kazakhstan.

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12 December 2020

First tuberculosis cases in Italy resistant to all tested drugs.

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12 December 2020

Genomic analysis reveals variation between Mycobacterium tuberculosis H37Rv and the attenuated M. tuberculosis H37Ra strain

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12 December 2020

ChIP-Seq and the complexity of bacterial transcriptional regulation

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12 December 2020

Using the Velvet de novo assembler for short-read sequencing technologies

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12 December 2020

Drug-resistant tuberculosis epidemic in the Western Cape driven by a virulent Beijing genotype strain.

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12 December 2020

A case of spondylitis tuberculosa in the Danish Neolithic Age

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12 December 2020

Pulmonary and osseous tuberculosis in an Egyptian mummy

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12 December 2020

Genetic diversity in Mycobacterium tuberculosis.

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12 December 2020

Negligible genetic diversity of mycobacterium tuberculosis host immune system protein targets: evidence of limited selective pressure

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12 December 2020

Identifiers

DOI

10.1038/NRG3664

1 reference

PubMed ID

24662221

Dimensions Publication ID

30 August 2017

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PubMed ID

24662221