The CD47-SIRPα signalling system: its physiological roles and therapeutic application (Q38195828)

30 August 2017

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title

The CD47-SIRPα signalling system: its physiological roles and therapeutic application (English)

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30 August 2017

Yoji Murata

1

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30 August 2017

Takenori Kotani

series ordinal

2

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30 August 2017

Hiroshi Ohnishi

series ordinal

3

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30 August 2017

Takashi Matozaki

series ordinal

4

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30 August 2017

12 March 2014

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30 August 2017

Journal of Biochemistry

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30 August 2017

155

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30 August 2017

335-344

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30 August 2017

6

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Functions and molecular mechanisms of the CD47-SIRPalpha signalling pathway

30 August 2017

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

Signal regulatory protein alpha (SIRPalpha)/CD47 interaction and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

Activation of protein-tyrosine phosphatase SH-PTP2 by a tyrosine-based activation motif of a novel brain molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

A novel membrane glycoprotein, SHPS-1, that binds the SH2-domain-containing protein tyrosine phosphatase SHP-2 in response to mitogens and cell adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

A family of proteins that inhibit signalling through tyrosine kinase receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

Integrin-mediated tyrosine phosphorylation of SHPS-1 and its association with SHP-2. Roles of Fak and Src family kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

The 'Shp'ing news: SH2 domain-containing tyrosine phosphatases in cell signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

Involvement of an SHP-2-Rho small G protein pathway in hepatocyte growth factor/scatter factor-induced cell scattering.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

Protein tyrosine phosphatase SHP-2: a proto-oncogene product that promotes Ras activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

Differential localization of Src homology 2 domain-containing protein tyrosine phosphatase substrate-1 and CD47 and its molecular mechanisms in cultured hippocampal neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

Negative regulation of phagocytosis in macrophages by the CD47-SHPS-1 system

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

Integrin-associated protein (CD47) and its ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

Role of CD47 as a marker of self on red blood cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

Roles of the complex formation of SHPS-1 with SHP-2 in insulin-stimulated mitogen-activated protein kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

CD47 promotes neuronal development through Src- and FRG/Vav2-mediated activation of Rac and Cdc42.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

Ectodomain shedding of SHPS-1 and its role in regulation of cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

Trans-endocytosis of CD47 and SHPS-1 and its role in regulation of the CD47-SHPS-1 system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

Corpse clearance defines the meaning of cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

Phagocytosis and innate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

CD47-signal regulatory protein alpha (SIRPalpha) regulates Fcgamma and complement receptor-mediated phagocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

SHPS-1 promotes the survival of circulating erythrocytes through inhibition of phagocytosis by splenic macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

Inhibition of "self" engulfment through deactivation of myosin-II at the phagocytic synapse between human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

CD47 functions as a molecular switch for erythrocyte phagocytosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

Negative regulation of platelet clearance and of the macrophage phagocytic response by the transmembrane glycoprotein SHPS-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

Platelet homeostasis is regulated by platelet expression of CD47 under normal conditions and in passive immune thrombocytopenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

CD47 (integrin-associated protein) engagement of dendritic cell and macrophage counterreceptors is required to prevent the clearance of donor lymphohematopoietic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

Polymorphism in Sirpa modulates engraftment of human hematopoietic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

Gene structure of mouse BIT/SHPS-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

Paired receptor specificity explained by structures of signal regulatory proteins alone and complexed with CD47

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

Species- and cell type-specific interactions between CD47 and human SIRPalpha.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

Phylogenetic divergence of CD47 interactions with human signal regulatory protein alpha reveals locus of species specificity. Implications for the binding site.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

Polymorphic Sirpa is the genetic determinant for NOD-based mouse lines to achieve efficient human cell engraftment

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

Functional CD47/signal regulatory protein alpha (SIRP(alpha)) interaction is required for optimal human T- and natural killer- (NK) cell homeostasis in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

Minimal "Self" peptides that inhibit phagocytic clearance and enhance delivery of nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

CD47 is an adverse prognostic factor and therapeutic antibody target on human acute myeloid leukemia stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

Anti-CD47 antibody synergizes with rituximab to promote phagocytosis and eradicate non-Hodgkin lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

Therapeutic antibody targeting of CD47 eliminates human acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

CD47 is upregulated on circulating hematopoietic stem cells and leukemia cells to avoid phagocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

CD47-signal regulatory protein-α (SIRPα) interactions form a barrier for antibody-mediated tumor cell destruction

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

Engineered SIRPα variants as immunotherapeutic adjuvants to anticancer antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

Signal-regulatory protein alpha (SIRPalpha) but not SIRPbeta is involved in T-cell activation, binds to CD47 with high affinity, and is expressed on immature CD34(+)CD38(-) hematopoietic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

The dendritic cell lineage: ontogeny and function of dendritic cells and their subsets in the steady state and the inflamed setting

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

Deficit of CD47 Results in a Defect of Marginal Zone Dendritic Cells, Blunted Immune Response to Particulate Antigen and Impairment of Skin Dendritic Cell Migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

Expression of the self-marker CD47 on dendritic cells governs their trafficking to secondary lymphoid organs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

Integrin-associated protein (IAP, also termed CD47) is involved in stroma-supported erythropoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

Signal regulatory protein α regulates the homeostasis of T lymphocytes in the spleen.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

Stromal cell-immune cell interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

Stromal cell regulation of homeostatic and inflammatory lymphoid organogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

Development of secondary lymphoid organs

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

Resistance to collagen-induced arthritis in SHPS-1 mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

Essential roles of SHPS-1 in induction of contact hypersensitivity of skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

Autoimmune animal models in the analysis of the CD47-SIRPα signaling pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

A role for CD47 in the development of experimental colitis mediated by SIRPalpha+CD103- dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

Janus-like opposing roles of CD47 in autoimmune brain inflammation in humans and mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

CD47 deficiency does not impede polymorphonuclear neutrophil transmigration but attenuates granulopoiesis at the postacute stage of colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

Essential roles of SIRPα in homeostatic regulation of skin dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

MFR, a putative receptor mediating the fusion of macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

Inhibitory regulation of osteoclast bone resorption by signal regulatory protein alpha.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

Lack of CD47 impairs bone cell differentiation and results in an osteopenic phenotype in vivo due to impaired signal regulatory protein α (SIRPα) signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

An essential role for the association of CD47 to SHPS-1 in skeletal remodeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

CD47 regulates bone mass and tumor metastasis to bone

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJB%2FMVU017

21 January 2018

Identifiers

DOI

10.1093/JB/MVU017

1 reference

release_nxsfne2o65abpno3prg35gvxwe

30 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/nxsfne2o65abpno3prg35gvxwe

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference