Treatment de-escalation in HPV-positive oropharyngeal carcinoma: ongoing trials, critical issues and perspectives (Q38195513)

30 August 2017

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title

Treatment de-escalation in HPV-positive oropharyngeal carcinoma: ongoing trials, critical issues and perspectives (English)

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30 August 2017

H Mirghani

1

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30 August 2017

F Amen

2

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30 August 2017

P Blanchard

3

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30 August 2017

F Moreau

4

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30 August 2017

J Guigay

5

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30 August 2017

D M Hartl

6

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30 August 2017

J Lacau St Guily

7

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30 August 2017

language of work or name

English

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publication date

4 April 2014

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International Journal of Cancer

30 August 2017

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30 August 2017

136

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30 August 2017

7

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30 August 2017

1494-1503

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Genome-wide DNA copy number alterations in head and neck squamous cell carcinomas with or without oncogene-expressing human papillomavirus

30 August 2017

1 reference

Evidence for a causal association between human papillomavirus and a subset of head and neck cancers

21 January 2018

1 reference

Human Papillomavirus and Rising Oropharyngeal Cancer Incidence in the United States

21 January 2018

1 reference

Incidence of human papillomavirus (HPV) positive tonsillar carcinoma in Stockholm, Sweden: an epidemic of viral-induced carcinoma?

21 January 2018

1 reference

Human papillomavirus and survival of patients with oropharyngeal cancer.

21 January 2018

1 reference

Improved survival of patients with human papillomavirus-positive head and neck squamous cell carcinoma in a prospective clinical trial

21 January 2018

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Future directions in research, treatment and prevention of HPV-related squamous cell carcinoma of the head and neck

21 January 2018

1 reference

Oropharyngeal cancer, human papilloma virus, and clinical trials

21 January 2018

1 reference

Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck

21 January 2018

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Cisplatin and fluorouracil with or without panitumumab in patients with recurrent or metastatic squamous-cell carcinoma of the head and neck (SPECTRUM): an open-label phase 3 randomised trial.

21 January 2018

1 reference

Phase II study of cisplatin plus cetuximab in advanced, recurrent, and previously treated cancers of the cervix and evaluation of epidermal growth factor receptor immunohistochemical expression: a Gynecologic Oncology Group study

21 January 2018

1 reference

Phase II trial of cetuximab in the treatment of persistent or recurrent squamous or non-squamous cell carcinoma of the cervix: a Gynecologic Oncology Group study

21 January 2018

1 reference

A phase II trial of erlotinib in recurrent squamous cell carcinoma of the cervix: a Gynecologic Oncology Group Study

21 January 2018

1 reference

Oropharyngeal cancers: relationship between epidermal growth factor receptor alterations and human papillomavirus status

21 January 2018

1 reference

Dysphagia and aspiration after chemoradiotherapy for head-and-neck cancer: which anatomic structures are affected and can they be spared by IMRT?

21 January 2018

1 reference

Dysphagia disorders in patients with cancer of the oropharynx are significantly affected by the radiation therapy dose to the superior and middle constrictor muscle: a dose-effect relationship.

21 January 2018

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Intensity-modulated radiotherapy of head and neck cancer aiming to reduce dysphagia: early dose-effect relationships for the swallowing structures

21 January 2018

1 reference

Atypical clinical behavior of p16-confirmed HPV-related oropharyngeal squamous cell carcinoma treated with radical radiotherapy.

21 January 2018

1 reference

Outcomes of HPV-related oropharyngeal cancer patients treated by radiotherapy alone using altered fractionation

21 January 2018

1 reference

Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): an update on 93 randomised trials and 17,346 patients

21 January 2018

1 reference

Taxane-cisplatin-fluorouracil as induction chemotherapy in locally advanced head and neck cancers: an individual patient data meta-analysis of the meta-analysis of chemotherapy in head and neck cancer group.

21 January 2018

1 reference

Cisplatin and fluorouracil alone or with docetaxel in head and neck cancer

21 January 2018

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Phase III study comparing cisplatin plus fluorouracil to paclitaxel, cisplatin, and fluorouracil induction chemotherapy followed by chemoradiotherapy in locally advanced head and neck cancer

21 January 2018

1 reference

Factors associated with severe late toxicity after concurrent chemoradiation for locally advanced head and neck cancer: an RTOG analysis

21 January 2018

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Deintensification candidate subgroups in human papillomavirus-related oropharyngeal cancer according to minimal risk of distant metastasis

21 January 2018

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Current trends in initial management of oropharyngeal cancer: the declining use of open surgery.

21 January 2018

1 reference

Transoral robotic surgery: a multicenter study to assess feasibility, safety, and surgical margins

21 January 2018

1 reference

Robotic surgery for oropharynx cancer: promise, challenges, and future directions

21 January 2018

1 reference

The role of transoral robotic surgery in the management of oropharyngeal cancer: a review of the literature

21 January 2018

1 reference

Efficacy of selective neck dissection: a review of 503 cases of elective and therapeutic treatment of the neck in squamous cell carcinoma of the upper aerodigestive tract

21 January 2018

1 reference

Expanded application of selective neck dissection with regard to nodal status

21 January 2018

1 reference

Early-stage squamous cell carcinoma of the oropharynx: radiotherapy vs. trans-oral robotic surgery (ORATOR)--study protocol for a randomized phase II trial

21 January 2018

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Patient preferences for oropharyngeal cancer treatment de-escalation

21 January 2018

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Human papilloma virus testing in oropharyngeal squamous cell carcinoma: what the clinician should know

21 January 2018

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HPV specific testing: a requirement for oropharyngeal squamous cell carcinoma patients

21 January 2018

1 reference

A novel algorithm for reliable detection of human papillomavirus in paraffin embedded head and neck cancer specimen.

21 January 2018

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p16 Immunohistochemistry as a standalone test for risk stratification in oropharyngeal squamous cell carcinoma

21 January 2018

1 reference

Prognostic significance of p16INK4A and human papillomavirus in patients with oropharyngeal cancer treated on TROG 02.02 phase III trial

21 January 2018

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Identification of clinically relevant HPV-related HNSCC: in p16 should we trust?

21 January 2018

1 reference

Head and neck squamous cell cancer and the human papillomavirus: summary of a National Cancer Institute State of the Science Meeting, November 9-10, 2008, Washington, D.C.

21 January 2018

1 reference

Vaccination against HPV-16 oncoproteins for vulvar intraepithelial neoplasia

21 January 2018

1 reference

Evidence for a role of the PD-1:PD-L1 pathway in immune resistance of HPV-associated head and neck squamous cell carcinoma

21 January 2018

1 reference

B7-H1 expression model for immune evasion in human papillomavirus-related oropharyngeal squamous cell carcinoma

21 January 2018

1 reference

Mission impossible: how HPV-associated head and neck cancers escape a primed immune response

21 January 2018

1 reference

Drug of the year: programmed death-1 receptor/programmed death-1 ligand-1 receptor monoclonal antibodies.

21 January 2018

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The phosphatidylinositol 3-Kinase AKT pathway in human cancer

21 January 2018

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Targeting the phosphoinositide 3-kinase pathway in cancer

21 January 2018

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Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1

21 January 2018

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The mutational landscape of head and neck squamous cell carcinoma

21 January 2018

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High frequency of activating PIK3CA mutations in human papillomavirus-positive oropharyngeal cancer

21 January 2018

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PIK3CA, HRAS and PTEN in human papillomavirus positive oropharyngeal squamous cell carcinoma.

21 January 2018

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Frequent mutation of the PI3K pathway in head and neck cancer defines predictive biomarkers

21 January 2018

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mTOR as a molecular target in HPV-associated oral and cervical squamous carcinomas

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/IJC.28847

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30 August 2017

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