Nature as a source of metabolites with cholinesterase-inhibitory activity: an approach to Alzheimer's disease treatment. (Q38162960)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24236980%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

title

Nature as a source of metabolites with cholinesterase-inhibitory activity: an approach to Alzheimer's disease treatment (English)

1 reference

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1 March 2020

0 references

1

1 reference

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1 March 2020

Federico Ferreres

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24236980%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Patrícia Valentão

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24236980%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Paula B. Andrade

4

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1 March 2020

author name string

Brígida R Pinho

1

1 reference

30 August 2017

Federico Ferreres

2

1 reference

30 August 2017

Patrícia Valentão

3

1 reference

30 August 2017

Paula B Andrade

4

1 reference

30 August 2017

16 May 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24236980%20AND%20SRC:MED&resulttype=core&format=json

Journal of Pharmacy and Pharmacology

1 March 2020

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24236980%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

volume

65

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1 March 2020

issue

12

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1 March 2020

page(s)

1681-1700

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Oxidative stress and neurodegenerative diseases: a review of upstream and downstream antioxidant therapeutic options

1 March 2020

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Pathogenic protein seeding in Alzheimer disease and other neurodegenerative disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

2012 Alzheimer's disease facts and figures

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Pathways towards and away from Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Abnormal tau, mitochondrial dysfunction, impaired axonal transport of mitochondria, and synaptic deprivation in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Aging and amyloid beta-induced oxidative DNA damage and mitochondrial dysfunction in Alzheimer's disease: implications for early intervention and therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Epidemiology of Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Amyloid precursor protein processing and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Alzheimer's risk variants in the clusterin gene are associated with alternative splicing

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

The neuronal sortilin-related receptor gene SORL1 and late-onset Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Neuropsychiatric symptoms in the dementias

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Multimodal techniques for diagnosis and prognosis of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Treatment of Alzheimer's disease: current status and new perspectives.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

The cholinergic system in aging and neuronal degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Patterns of memory failure after scopolamine treatment: implications for cholinergic hypotheses of dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Scopolamine impairs human recognition memory: data and modeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

The emerging role of human esterases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Neurobiology of butyrylcholinesterase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Tissue distribution of human acetylcholinesterase and butyrylcholinesterase messenger RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

The cholinergic system in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Acetylcholinesterase inhibitors from plants and fungi

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Correlation of cholinergic abnormalities with senile plaques and mental test scores in senile dementia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Selective loss of central cholinergic neurons in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Amelioration of amyloid load by anti-Abeta single-chain antibody in Alzheimer mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Acetylcholinesterase inhibition in Alzheimer's Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

The relevance of higher plants in lead compound discovery programs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Herbal extracts and phytochemicals: plant secondary metabolites and the enhancement of human brain function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Anti-Alzheimer and antioxidant activities of Coptidis Rhizoma alkaloids

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Cholinesterase inhibition by potato glycoalkaloids slows mivacurium metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Huperzine A, a potential therapeutic agent for treatment of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Acetylcholinesterase inhibitors from the toadstool Cortinarius infractus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Juliflorine: a potent natural peripheral anionic-site-binding inhibitor of acetylcholinesterase with calcium-channel blocking potential, a leading candidate for Alzheimer's disease therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Petrosamine, a potent anticholinesterase pyridoacridine alkaloid from a Thai marine sponge Petrosia n. sp.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

The long-acting cholinesterase inhibitor heptyl-physostigmine attenuates the scopolamine-induced learning impairment of rats in a 14-unit T-maze

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Actions of pyridostigmine and organophosphate agents on chick cells, mice, and chickens

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

In vitro and in vivo characterization of recombinant human butyrylcholinesterase (Protexia) as a potential nerve agent bioscavenger

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Coumarins isolated from Angelica gigas inhibit acetylcholinesterase: structure-activity relationships

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Insecticidal effect of phthalides and furanocoumarins from Angelica acutiloba against Drosophila melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Effects of methoxsalen from Poncirus trifoliata on acetylcholinesterase and trimethyltin-induced learning and memory impairment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Acetylcholinesterase inhibitors from the twigs of Vaccinium oldhami Miquel

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Galangin, a flavonol derived from Rhizoma Alpiniae Officinarum, inhibits acetylcholinesterase activity in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Cholinesterase inhibitors from Cleistocalyx operculatus buds

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Leufolins A and B, potent butyrylcholinesterase-inhibiting flavonoid glucosides from Leucas urticifolia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Cholinestrase inhibitory effects of geranylated flavonoids from Paulownia tomentosa fruits.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Cholinesterase inhibitory effects of the extracts and compounds of Maclura pomifera (Rafin.) Schneider.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Cholinesterase inhibitory activities of some flavonoid derivatives and chosen xanthone and their molecular docking studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Anticholinesterase activity of plastoquinones from Sargassum sagamianum: lead compounds for Alzheimer's disease therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

(+)-Alpha-viniferin, a stilbene trimer from Caragana chamlague, inhibits acetylcholinesterase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

In-vitro inhibition of human erythrocyte acetylcholinesterase by salvia lavandulaefolia essential oil and constituent terpenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Inhibition of acetylcholinesterase activity by bicyclic monoterpenoids

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Butyryl- and acetyl-cholinesterase inhibitory activities in essential oils of Salvia species and their constituents

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Interaction study of two diterpenes, cryptotanshinone and dihydrotanshinone, to human acetylcholinesterase and butyrylcholinesterase by molecular docking and kinetic analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Labdane-type diterpenoids from Leonurus heterophyllus and their cholinesterase inhibitory activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Three new cholinesterase-inhibiting cis-clerodane diterpenoids from Otostegia limbata

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Myrtenal inhibits acetylcholinesterase, a known Alzheimer target

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Leishmanicidal and cholinesterase inhibiting activities of phenolic compounds from Allanblackia monticola and Symphonia globulifera.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Xanthones from Gentianella amarella ssp. acuta with acetylcholinesterase and monoamine oxidase inhibitory activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

(+)-Arisugacin A--computational evidence of a dual binding site covalent inhibitor of acetylcholinesterase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

An overview on natural cholinesterase inhibitors--a multi-targeted drug class--and their mass production

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Lead finding for acetyl cholinesterase inhibitors from natural origin: structure activity relationship and scope

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Accommodation of physostigmine and its analogues by acetylcholinesterase is dominated by hydrophobic interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Selective butyrylcholinesterase inhibition elevates brain acetylcholine, augments learning and lowers Alzheimer beta-amyloid peptide in rodent

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Effects of berberine on β-secretase activity in a rabbit model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Cloning and expression of acetylcholinesterase from Bungarus fasciatus venom. A new type of cooh-terminal domain; involvement of a positively charged residue in the peripheral site

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Galantamine treatment in Alzheimer's disease: response and long-term outcome in a routine clinical setting

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

N-Alkylated galanthamine derivatives: Potent acetylcholinesterase inhibitors from Leucojum aestivum

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Geissospermum vellosii stembark: anticholinesterase activity and improvement of scopolamine-induced memory deficits.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Docking of the alkaloid geissospermine into acetylcholinesterase: a natural scaffold targeting the treatment of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

The psychopharmacology of huperzine A: an alkaloid with cognitive enhancing and neuroprotective properties of interest in the treatment of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Huperzine A alleviates synaptic deficits and modulates amyloidogenic and nonamyloidogenic pathways in APPswe/PS1dE9 transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Huperzine A ameliorates cognitive deficits and oxidative stress in the hippocampus of rats exposed to acute hypobaric hypoxia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Role of the catalytic triad and oxyanion hole in acetylcholinesterase catalysis: an ab initio QM/MM study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

A phase II trial of huperzine A in mild to moderate Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Acetylcholinesterase enzyme inhibitory effects of amaryllidaceae alkaloids

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Synthesis and biological evaluation of lycorine derivatives as dual inhibitors of human acetylcholinesterase and butyrylcholinesterase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Acetylcholinesterase inhibitory activity of lycopodane-type alkaloids from the Icelandic Lycopodium annotinum ssp. alpestre

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Cytotoxicity and acetylcholinesterase inhibitory activity of an isolated crinine alkaloid from Boophane disticha (Amaryllidaceae).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Acetylcholinesterase inhibitory activity of scopolin and scopoletin discovered by virtual screening of natural products

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Inhibitory effect of Poncirus trifoliate on acetylcholinesterase and attenuating activity against trimethyltin-induced learning and memory impairment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Decursin from Angelica gigas mitigates amnesia induced by scopolamine in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Design, synthesis and biological evaluation of coumarin alkylamines as potent and selective dual binding site inhibitors of acetylcholinesterase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Structure-antioxidant activity relationships of flavonoids and phenolic acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Flavonoids as acetylcholinesterase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Design, synthesis and evaluation of flavonoid derivatives as potent AChE inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Fustin flavonoid attenuates beta-amyloid (1-42)-induced learning impairment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Naringenin from Citrus junos has an inhibitory effect on acetylcholinesterase and a mitigating effect on amnesia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Structural aspects of flavonoids as inhibitors of human butyrylcholinesterase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Anticholinesterase activity of 7-methoxyflavones isolated from Kaempferia parviflora.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Luteolin enhances cholinergic activities in PC12 cells through ERK1/2 and PI3K/Akt pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Molecular mechanisms of quinone cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Pyranonaphthoquinone derivatives of eleutherin, ventiloquinone L, thysanone and nanaomycin A possessing a diverse topoisomerase II inhibition and cytotoxicity spectrum

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Juglone, an inhibitor of the peptidyl-prolyl isomerase Pin1, also directly blocks transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Pharmacological actions of Thespesia populnea relevant to Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Pharmacometrics of stilbenes: seguing towards the clinic.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Anticholinesterase and pediculicidal activities of monoterpenoids

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Synergistic and antagonistic interactions of anticholinesterase terpenoids in Salvia lavandulaefolia essential oil.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Novel diterpenoid acetylcholinesterase inhibitors from Salvia miltiorhiza

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Bioactive constituents of Salvia chrysophylla Stapf

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

New butyrylcholinesterase inhibitory steroid and peroxy acid from Leucas urticifolia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Withanolides, a new class of natural cholinesterase inhibitors with calcium antagonistic properties.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Polycyclic aromatic hydrocarbons inhibit the activity of acetylcholinesterase purified from electric eel.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Xanthones from Gentiana campestris as new acetylcholinesterase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Design, synthesis, and biological evaluation of new territrem B analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Arisugacins, selective acetylcholinesterase inhibitors of microbial origin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081

Molecular basis of inhibitory activities of berberine against pathogenic enzymes in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJPHP.12081