A golden future in medicinal inorganic chemistry: the promise of anticancer gold organometallic compounds (Q38162354)

30 August 2017

A golden future in medicinal inorganic chemistry: the promise of anticancer gold organometallic compounds (English)

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30 August 2017

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Benoît Bertrand

1

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Angela Casini

object named as

Angela Casini

series ordinal

2

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language of work or name

English

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publication date

1 March 2014

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30 August 2017

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30 August 2017

43

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30 August 2017

4209-4219

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30 August 2017

11

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Excursions in polynuclear platinum DNA binding

30 August 2017

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A categorization of metal anticancer compounds based on their mode of action

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Metal complex SERMs (selective oestrogen receptor modulators). The influence of different metal units on breast cancer cell antiproliferative effects

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Anti-cancer potential of gold complexes

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Gold dithiocarbamate derivatives as potential antineoplastic agents: design, spectroscopic properties, and in vitro antitumor activity.

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Molecular mechanisms and proposed targets for selected anticancer gold compounds

21 January 2018

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Noble metal-dithiocarbamates precious allies in the fight against cancer.

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Gold compounds as therapeutic agents for human diseases

21 January 2018

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Substrate and inhibitor specificities differ between human cytosolic and mitochondrial thioredoxin reductases: Implications for development of specific inhibitors.

21 January 2018

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Cysteine proteases as targets for metal-based drugs

21 January 2018

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Deubiquitinases as potential anti-cancer targets for gold(III) complexes

21 January 2018

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Deubiquitinases in cancer: new functions and therapeutic options.

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Gold(I)-mediated inhibition of protein tyrosine phosphatases: a detailed in vitro and cellular study

21 January 2018

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Structural and solution chemistry, antiproliferative effects, and DNA and protein binding properties of a series of dinuclear gold(III) compounds with bipyridyl ligands

21 January 2018

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Cyclometalation using d-block transition metals: fundamental aspects and recent trends

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Antitumor properties of some 2-[(dimethylamino)methyl]phenylgold(III) complexes

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Metal compounds for the treatment of parasitic diseases

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Thioredoxin reductase and cancer cell growth inhibition by organogold(III) compounds

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Inhibition of the cathepsin cysteine proteases B and K by square-planar cycloaurated gold(III) compounds and investigation of their anti-cancer activity

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A dual cytotoxic and anti-angiogenic water-soluble gold(III) complex induces endoplasmic reticulum damage in HeLa cells

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Iminophosphorane-organogold(III) complexes induce cell death through mitochondrial ROS production

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Synthesis of apoptosis-inducing iminophosphorane organogold(III) complexes and study of their interactions with biomolecular targets

21 January 2018

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Gold(III) complexes with bipyridyl ligands: solution chemistry, cytotoxicity, and DNA binding properties

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Chemistry, antiproliferative properties, tumor selectivity, and molecular mechanisms of novel gold(III) compounds for cancer treatment: a systematic study

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Solution chemistry and cytotoxic properties of novel organogold(III) compounds

21 January 2018

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Gold complexes inhibit mitochondrial thioredoxin reductase: consequences on mitochondrial functions

21 January 2018

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Mechanistic studies on two dinuclear organogold(III) compounds showing appreciable antiproliferative properties and a high redox stability

21 January 2018

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Anticancer cyclometalated [Au(III)m(C(wedge)N(wedge)C)mL]n+ compounds: Synthesis and cytotoxic properties

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Organogold(III) supramolecular polymers for anticancer treatment

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N-Heterocyclic carbene metal complexes in medicinal chemistry

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Metal N-heterocyclic carbene complexes as potential antitumor metallodrugs

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Mitochondria-targeted chemotherapeutics: the rational design of gold(I) N-heterocyclic carbene complexes that are selectively toxic to cancer cells and target protein selenols in preference to thiols.

21 January 2018

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Mitochondrial permeability transition induced by dinuclear gold(I)-carbene complexes: potential new antimitochondrial antitumour agents.

21 January 2018

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Role of membrane potential in the regulation of cell proliferation and differentiation

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Fluorescent silver(I) and gold(I)-N-heterocyclic carbene complexes with cytotoxic properties: mechanistic insights

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Structure, mechanism and regulation of peroxiredoxins

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Gold(I) carbene complexes causing thioredoxin 1 and thioredoxin 2 oxidation as potential anticancer agents

21 January 2018

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Comparative in vitro evaluation of N-heterocyclic carbene gold(I) complexes of the benzimidazolylidene type.

21 January 2018

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Synthesis and biological activity of ester- and amide-functionalized imidazolium salts and related water-soluble coinage metal N-heterocyclic carbene complexes

21 January 2018

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Synthesis, characterization, and in vitro studies of bis[1,3-diethyl-4,5-diarylimidazol-2-ylidene]gold(I/III) complexes

21 January 2018

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NHC gold halide complexes derived from 4,5-diarylimidazoles: synthesis, structural analysis, and pharmacological investigations as potential antitumor agents

21 January 2018

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The application of DNA and RNA G-quadruplexes to therapeutic medicines.

21 January 2018

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Chemistry in human telomere biology: structure, function and targeting of telomere DNA/RNA.

21 January 2018

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Targeting G-quadruplexes in gene promoters: a novel anticancer strategy?

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G-quadruplex nucleic acids as therapeutic targets

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Cyclometalated gold(III) complexes with N-heterocyclic carbene ligands as topoisomerase I poisons

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Cationic gold(I) heteroleptic complexes bearing a pyrazole-derived N-heterocyclic carbene: syntheses, characterizations, and cytotoxic activities.

21 January 2018

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Synthesis, structural characterisation and anti-proliferative activity of NHC gold amino acid and peptide conjugates

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Gold(I)-NHC complexes of antitumoral diarylimidazoles: structures, cellular uptake routes and anticancer activities

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Applications of gold(I) alkynyl systems: a growing field to explore

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Metal alkynyl sigma complexes: synthesis and materials

21 January 2018

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Synthesis and biological studies of some gold(I) complexes containing functionalised alkynes

21 January 2018

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Antitumor activity of diethynylfluorene derivatives of gold(I).

21 January 2018

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On the biological properties of alkynyl phosphine gold(I) complexes.

21 January 2018

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Preparation and incubation of precision-cut liver and intestinal slices for application in drug metabolism and toxicity studies.

21 January 2018

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Application of mass spectrometric techniques to delineate the modes-of-action of anticancer metallodrugs

21 January 2018

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Isolation of neutral mono- and dinuclear gold complexes of cyclic (alkyl)(amino)carbenes.

21 January 2018

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Thioredoxin reductase, an emerging target for anticancer metallodrugs. Enzyme inhibition by cytotoxic gold(iii) compounds studied with combined mass spectrometry and biochemical assays

21 January 2018

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Thioredoxin reductase: A target for gold compounds acting as potential anticancer drugs

21 January 2018

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Reactions of gold(III) complexes with serum albumin

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3DT52524D

Protein metalation by metal-based drugs: reactions of cytotoxic gold compounds with cytochrome c and lysozyme

21 January 2018

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Medicinal gold compounds form tight adducts with the copper chaperone Atox-1: biological and pharmacological implications

21 January 2018

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A dinuclear cyclometalated gold(iii)–phosphine complex targeting thioredoxin reductase inhibits hepatocellular carcinoma in vivo

21 January 2018

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Luminescent cyclometalated gold(iii) complexes

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21 January 2018

Identifiers

DOI

10.1039/C3DT52524D

1 reference

30 August 2017

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PubMed ID

24225667