Osteoimmunology: the expanding role of immunoreceptors in osteoclasts and bone remodeling (Q38116019)

29 August 2017

Osteoimmunology: the expanding role of immunoreceptors in osteoclasts and bone remodeling (English)

1 reference

29 August 2017

Courtney L Long

1

1 reference

PMCID

3685299

29 August 2017

Mary Beth Humphrey

series ordinal

2

1 reference

29 August 2017

1 April 2012

1 reference

29 August 2017

1 reference

29 August 2017

1

1 reference

https://scigraph.springernature.com/pub.10.1038/bonekey.2012.59

29 August 2017

0 references

cites work

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Sclerostin stimulates osteocyte support of osteoclast activity by a RANKL-dependent pathway

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Evidence for osteocyte regulation of bone homeostasis through RANKL expression

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Matrix-embedded cells control osteoclast formation

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OSCAR is a collagen receptor that costimulates osteoclastogenesis in DAP12-deficient humans and mice

6 September 2017

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6 September 2017

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6 September 2017

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Macrophage colony-stimulating factor induces the proliferation and survival of macrophages via a pathway involving DAP12 and beta-catenin

6 September 2017

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RANK, RANKL and osteoprotegerin in bone biology and disease.

6 September 2017

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Signal adaptor DAP10 associates with MDL-1 and triggers osteoclastogenesis in cooperation with DAP12

6 September 2017

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Identification of cell cycle-arrested quiescent osteoclast precursors in vivo

6 September 2017

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DAP10- and DAP12-associated receptors in innate immunity

6 September 2017

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Inhibitory immunoglobulin-like receptors LILRB and PIR-B negatively regulate osteoclast development

6 September 2017

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DAP12 couples c-Fms activation to the osteoclast cytoskeleton by recruitment of Syk.

6 September 2017

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CLEC5A is critical for dengue-virus-induced lethal disease

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Osteoclast inhibitory peptide-1 (OIP-1) inhibits measles virus nucleocapsid protein stimulated osteoclast formation/activity

6 September 2017

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Bone microenvironment specific roles of ITAM adapter signaling during bone remodeling induced by acute estrogen-deficiency

6 September 2017

1 reference

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Pathological role of osteoclast costimulation in arthritis-induced bone loss.

6 September 2017

1 reference

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Syk, c-Src, the alphavbeta3 integrin, and ITAM immunoreceptors, in concert, regulate osteoclastic bone resorption

6 September 2017

1 reference

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PLCgamma2 regulates osteoclastogenesis via its interaction with ITAM proteins and GAB2.

6 September 2017

1 reference

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OSCAR is an FcRgamma-associated receptor that is expressed by myeloid cells and is involved in antigen presentation and activation of human dendritic cells

6 September 2017

1 reference

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The immunomodulatory adapter proteins DAP12 and Fc receptor gamma-chain (FcRgamma) regulate development of functional osteoclasts through the Syk tyrosine kinase

6 September 2017

1 reference

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Nasu-Hakola disease (polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy--PLOSL): a dementia associated with bone cystic lesions. From clinical to genetic and molecular aspects

6 September 2017

1 reference

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CMRF-35-like molecule-1, a novel mouse myeloid receptor, can inhibit osteoclast formation

6 September 2017

1 reference

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DAP12/TREM2 deficiency results in impaired osteoclast differentiation and osteoporotic features

6 September 2017

1 reference

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Impaired differentiation of osteoclasts in TREM-2-deficient individuals

6 September 2017

1 reference

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Pattern recognition by TREM-2: binding of anionic ligands

6 September 2017

1 reference

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Mutations in two genes encoding different subunits of a receptor signaling complex result in an identical disease phenotype

6 September 2017

1 reference

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A novel member of the leukocyte receptor complex regulates osteoclast differentiation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685299

The ITAM-bearing transmembrane adaptor DAP12 in lymphoid and myeloid cell function

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685299

Loss-of-function mutations in TYROBP (DAP12) result in a presenile dementia with bone cysts.

6 September 2017

1 reference

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Commitment and differentiation of osteoclast precursor cells by the sequential expression of c-Fms and receptor activator of nuclear factor kappaB (RANK) receptors

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685299

Control of bone resorption by hematopoietic tissue. The induction and reversal of congenital osteopetrosis in mice through use of bone marrow and splenic transplants

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685299

TREM2- and DAP12-dependent activation of PI3K requires DAP10 and is inhibited by SHIP1.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685299

The surface-exposed chaperone, Hsp60, is an agonist of the microglial TREM2 receptor

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685299

Murine dendritic cell transdifferentiation into osteoclasts is differentially regulated by innate and adaptive cytokines

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685299

The signaling adapter protein DAP12 regulates multinucleation during osteoclast development

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685299

MLO-Y4 osteocyte-like cells support osteoclast formation and activation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685299

Inhibitory regulation of osteoclast bone resorption by signal regulatory protein alpha.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685299

A role for TREM2 ligands in the phagocytosis of apoptotic neuronal cells by microglia

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685299

Costimulatory signals mediated by the ITAM motif cooperate with RANKL for bone homeostasis.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685299

Congenital osteoclast deficiency in osteopetrotic (op/op) mice is cured by injections of macrophage colony-stimulating factor

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685299

Lineage-committed osteoclast precursors circulate in blood and settle down into bone.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685299

Myeloid blasts are the mouse bone marrow cells prone to differentiate into osteoclasts.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685299

Tumor necrosis factor-alpha increases circulating osteoclast precursor numbers by promoting their proliferation and differentiation in the bone marrow through up-regulation of c-Fms expression.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685299

TREM2, a DAP12-associated receptor, regulates osteoclast differentiation and function

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685299

Vav3 regulates osteoclast function and bone mass

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685299

High dose M-CSF partially rescues the Dap12-/- osteoclast phenotype

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685299

Bifurcation of osteoclasts and dendritic cells from common progenitors

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685299

Ly49Q, an ITIM-bearing NK receptor, positively regulates osteoclast differentiation

31 August 2018

1 reference

12 December 2020

Identification of multiple osteoclast precursor populations in murine bone marrow

1 reference

12 December 2020

Congenital osteopetrosis in mice cured by parabiotic union with normal siblings

1 reference

12 December 2020

Targeted ablation of osteocytes induces osteoporosis with defective mechanotransduction

1 reference

12 December 2020

A Clonogenic Bone Marrow Progenitor Specific for Macrophages and Dendritic Cells

1 reference

12 December 2020

Immature dendritic cell transdifferentiation into osteoclasts: a novel pathway sustained by the rheumatoid arthritis microenvironment

1 reference

12 December 2020

Identifiers

DOI

10.1038/BONEKEY.2012.59

1 reference

PMCID

3685299

Dimensions Publication ID

29 August 2017

0 references

1 reference

29 August 2017

1 reference

PMCID

3685299