A possibly sigma-1 receptor mediated role of dimethyltryptamine in tissue protection, regeneration, and immunity (Q38101865)

28 August 2017

A possibly sigma-1 receptor mediated role of dimethyltryptamine in tissue protection, regeneration, and immunity (English)

1 reference

28 August 2017

Ede Frecska

1

1 reference

28 August 2017

Attila Szabo

2

1 reference

28 August 2017

Michael J Winkelman

3

1 reference

28 August 2017

Luis E Luna

4

1 reference

28 August 2017

Dennis J McKenna

5

1 reference

28 August 2017

language of work or name

1 reference

26 April 2013

1 reference

Journal of Neural Transmission

28 August 2017

1 reference

28 August 2017

120

1 reference

28 August 2017

9

1 reference

28 August 2017

1295-1303

1 reference

https://scigraph.springernature.com/pub.10.1007/s00702-013-1024-y

28 August 2017

0 references

cites work

5-HT and the immune system

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

Enzymatic formation of psychotomimetic metabolites from normally occurring compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

Sigma receptors and cancer: possible involvement of ion channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

N, N-dimethyltryptamine: an endogenous hallucinogen.

21 January 2018

2 references

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

21 January 2018

12 December 2020

Comparison of the brain levels of N,N-dimethyltryptamine and alpha, alpha, beta, beta-tetradeutero-N-N-dimethyltryptamine following intraperitoneal injection. The in vivo kinetic isotope effect

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

A critical review of reports of endogenous psychedelic N, N-dimethyltryptamines in humans: 1955-2010.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

A proposed mechanism for the visions of dream sleep

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

Emerging strategies to strengthen the anti-tumour activity of type I interferons: overcoming survival pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

The in vitro identification of dimethyltryptamine (DMT) in mammalian brain and its characterization as a possible endogenous neuroregulatory agent

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

Nicotine and serotonin in immune regulation and inflammatory processes: a perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

Determination and physiological disposition of dimethyltryptamine and diethyltryptamine in rat brain, liver and plasma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

Sigma receptor modulators: a patent review

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

Dimethyltryptamine and other hallucinogenic tryptamines exhibit substrate behavior at the serotonin uptake transporter and the vesicle monoamine transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

Afobazole modulates neuronal response to ischemia and acidosis via activation of sigma-1 receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

Afobazole modulates microglial function via activation of both sigma-1 and sigma-2 receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

Neuronal correlates of visual and auditory alertness in the DMT and ketamine model of psychosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

Differential interactions of dimethyltryptamine (DMT) with 5-HT1A and 5-HT2 receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

Autonomic, neuroendocrine, and immunological effects of ayahuasca: a comparative study with d-amphetamine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

The hallucinogen N,N-dimethyltryptamine (DMT) is an endogenous sigma-1 receptor regulator

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

Cocaine-induced HIV-1 expression in microglia involves sigma-1 receptors and transforming growth factor-beta1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

Neuroprotective effects of the sigma-1 receptor ligand PRE-084 against excitotoxic perinatal brain injury in newborn mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

Selective sigma receptor agonist 2-(4-morpholinethyl)1-phenylcyclohexanecarboxylate (PRE084) promotes neuroprotection and neurite elongation through protein kinase C (PKC) signaling on motoneurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

Sigma receptors suppress multiple aspects of microglial activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

Sigma-1 receptor ligands: potential in the treatment of neuropsychiatric disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

Sigma-1 receptor chaperones at the ER-mitochondrion interface regulate Ca(2+) signaling and cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

Endogenous psychoactive tryptamines reconsidered: an anxiolytic role for dimethyltryptamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

Behavioural changes induced by N,N-dimethyl-tryptamine in rodents

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

Potentially hallucinogenic 5-hydroxytryptamine receptor ligands bufotenine and dimethyltryptamine in blood and tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

Sigma-1 receptor activation prevents intracellular calcium dysregulation in cortical neurons during in vitro ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

Protection of cellular and mitochondrial functions against liver ischemia by N-benzyl-N'-(2-hydroxy-3,4-dimethoxybenzyl)-piperazine (BHDP), a sigma1 ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

Differences in gene expression levels between early and later stages of human lung development are opposite to those between normal lung tissue and non-small lung cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

The sigma-1 receptor: roles in neuronal plasticity and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

Identification of markers of prostate cancer progression using candidate gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

Interferon lambda: a new sword in cancer immunotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

Serotonin provides an accessory signal to enhance T-cell activation by signaling through the 5-HT7 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

Indolethylamine-N-methyltransferase in developing rabbit lung.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

Neuroprotective effects of high affinity Σ1 receptor selective compounds.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

Sigma-1R agonist improves motor function and motoneuron survival in ALS mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

A peptide-like inhibitor of N-methyltransferase in rabbit brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

Development of the sigma-1 receptor in C-terminals of motoneurons and colocalization with the N,N'-dimethyltryptamine forming enzyme, indole-N-methyl transferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

4-IBP, a sigma1 receptor agonist, decreases the migration of human cancer cells, including glioblastoma cells, in vitro and sensitizes them in vitro and in vivo to cytotoxic insults of proapoptotic and proautophagic drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

Sigma-1 receptor stimulation attenuates calcium influx through activated L-type Voltage Gated Calcium Channels in purified retinal ganglion cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

The effects of non-medically used psychoactive drugs on monoamine neurotransmission in rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

Cystathionine β-synthase deficiency causes infertility by impairing decidualization and gene expression networks in uterus implantation sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

A novel form of immune signaling revealed by transmission of the inflammatory mediator serotonin between dendritic cells and T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

The sigma-1 receptor protects against cellular oxidative stress and activates antioxidant response elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

Sigma receptor agonist 2-(4-morpholinethyl)1 phenylcyclohexanecarboxylate (Pre084) increases GDNF and BiP expression and promotes neuroprotection after root avulsion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

Effects of the sigma-1 receptor agonist 1-(3,4-dimethoxyphenethyl)-4-(3-phenylpropyl)-piperazine dihydro-chloride on inflammation after stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

A prototypical Sigma-1 receptor antagonist protects against brain ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

In vivo metabolism of 5-methoxy-N,N-dimethyltryptamine and N,N-dimethyltryptamine in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

Agonist properties of N,N-dimethyltryptamine at serotonin 5-HT2A and 5-HT2C receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

Differential tolerance to biological and subjective effects of four closely spaced doses of N,N-dimethyltryptamine in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

When the endogenous hallucinogenic trace amine N,N-dimethyltryptamine meets the sigma-1 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

The sigma-1 receptor chaperone as an inter-organelle signaling modulator

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

Temporally designed treatment of melanoma cells by ATRA and polyI: C results in enhanced chemokine and IFNβ secretion controlled differently by TLR3 and MDA5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

Dimethyltryptamin: its metabolism in man; the relation to its psychotic effect to the serotonin metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

Stimulation of σ1-receptor restores abnormal mitochondrial Ca²⁺ mobilization and ATP production following cardiac hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

11C-labeling of indolealkylamine alkaloids and the comparative study of their tissue distributions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

sigma-1 receptors protect RGC-5 cells from apoptosis by regulating intracellular calcium, Bax levels, and caspase-3 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

Human indolethylamine N-methyltransferase: cDNA cloning and expression, gene cloning, and chromosomal localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

Sigma-1 receptors regulate hippocampal dendritic spine formation via a free radical-sensitive mechanism involving Rac1xGTP pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

Insights into the Sigma-1 receptor chaperone's cellular functions: a microarray report

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

SA4503, a sigma-1 receptor agonist, prevents cultured cortical neurons from oxidative stress-induced cell death via suppression of MAPK pathway activation and glutamate receptor expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

Sigma 1 receptor agonists act as neuroprotective drugs through inhibition of inducible nitric oxide synthase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

Endogenous hallucinogens as ligands of the trace amine receptors: a possible role in sensory perception.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

Controlling the kinetics of interferon transgene expression for improved gene therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

Interferon-gamma in the first-line therapy of ovarian cancer: a randomized phase III trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

In vivo kinetics and displacement study of a carbon-11-labeled hallucinogen, N,N-[11C]dimethyltryptamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

Sigma receptor agonists provide neuroprotection in vitro by preserving bcl-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

Sigma receptor ligand 4-phenyl-1-(4-phenylbutyl)-piperidine modulates neuronal nitric oxide synthase/postsynaptic density-95 coupling mechanisms and protects against neonatal ischemic degeneration of striatal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

Sigma-1 receptor agonists provide neuroprotection against gp120 via a change in bcl-2 expression in mouse neuronal cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-013-1024-Y

Sigma receptor ligands: applications in inflammation and oncology.

21 January 2018

1 reference

12 December 2020

Rabbit serum monoamine oxidase. II. Determinants of substrate specificity

1 reference

12 December 2020

The sigma-1 receptor enhances brain plasticity and functional recovery after experimental stroke

1 reference

12 December 2020

Accumulation of N,N-dimethyltryptamine in rat brain cortical slices

1 reference

12 December 2020

The sigma enigma: can sigma receptors provide a novel target for disorders of mood and cognition?

1 reference

12 December 2020

A proposal for the classification of sigma binding sites

1 reference

12 December 2020

Recreational use of naturally occurring dimethyltryptamine--contributing to psychosis?

1 reference

12 December 2020

Hallucinogenic drugs in psychiatric research and treatment. Perspectives and prospects

1 reference

12 December 2020

Serotonin and lysergic acid diethylamide binding in rat brain membranes: relationship to postsynaptic serotonin receptors

1 reference

12 December 2020

The serotonin receptor agonist 5-methoxy-N,N-dimethyltryptamine facilitates noradrenaline release from rat spinal cord slices and inhibits monoamine oxidase activity

1 reference

12 December 2020

Are hallucinogens psychoheuristic?

1 reference

12 December 2020

Immunomodulatory functions of type I interferons

1 reference

12 December 2020

In vivo long-term kinetics of radiolabeled n,n-dimethyltryptamine and tryptamine

1 reference

12 December 2020

In vivo inhibition of endotoxin-induced pro-inflammatory cytokines production by the sigma ligand SR 31747

1 reference

12 December 2020

Differentiation of 5-hydroxytryptamine2 receptor subtypes using 125I-R-(-)2,5-dimethoxy-4-iodo-phenylisopropylamine and 3H-ketanserin.

1 reference

12 December 2020

Antagonist properties of d-LSD at 5-hydroxytryptamine2 receptors.

1 reference

12 December 2020

10.1007/S00702-013-1024-Y

Identifiers

DOI

1 reference

28 August 2017

1 reference