Bromodomains as therapeutic targets in cancer (Q38094645)

28 August 2017

Bromodomains as therapeutic targets in cancer (English)

1 reference

28 August 2017

Isaia Barbieri

1

1 reference

PubMed ID

23543289

28 August 2017

Ester Cannizzaro

series ordinal

2

1 reference

PubMed ID

23543289

28 August 2017

Mark A Dawson

series ordinal

3

1 reference

28 August 2017

28 March 2013

1 reference

Briefings in functional genomics

28 August 2017

1 reference

28 August 2017

12

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28 August 2017

3

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28 August 2017

219-230

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Targeting epigenetic readers in cancer.

28 August 2017

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

Cancer epigenetics: from mechanism to therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

Cancer genetics and epigenetics: two sides of the same coin?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

Cancer epigenomics: beyond genomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

The role of mutations in epigenetic regulators in myeloid malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

Histone deacetylases and cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

Histone deacetylase inhibitors in cancer therapy: is transcription the primary target?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

A phase II study of the histone deacetylase inhibitor vorinostat combined with tamoxifen for the treatment of patients with hormone therapy-resistant breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

Brd4 coactivates transcriptional activation of NF-kappaB via specific binding to acetylated RelA

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

Bromodomain protein Brd3 associates with acetylated GATA1 to promote its chromatin occupancy at erythroid target genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

Structure and acetyl-lysine recognition of the bromodomain

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

Structure and ligand of a histone acetyltransferase bromodomain

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

Place your BETs: the therapeutic potential of bromodomains

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

The bromodomain interaction module

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

ATAD2 is a novel cofactor for MYC, overexpressed and amplified in aggressive tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

Comparative kinome analysis to identify putative colon tumor biomarkers

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

Reversible acetylation of the chromatin remodelling complex NoRC is required for non-coding RNA-dependent silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

A novel family of bromodomain genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

Incidence and diversity of PAX5 fusion genes in childhood acute lymphoblastic leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

The double bromodomain proteins Brd2 and Brd3 couple histone acetylation to transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

Tumor-specific and proliferation-specific gene expression typifies murine transgenic B cell lymphomagenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

BRD-NUT oncoproteins: a family of closely related nuclear proteins that block epithelial differentiation and maintain the growth of carcinoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

Selective inhibition of BET bromodomains

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

BRD8 is a potential chemosensitizing target for spindle poisons in colorectal cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

Expression of multiple epigenetically regulated cancer/germline genes in nonsmall cell lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

The multidomain protein Brpf1 binds histones and is required for Hox gene expression and segmental identity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

Translocation t(X;11)(q13;q23) in B-cell chronic lymphocytic leukemia disrupts two novel genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

CECR2, a protein involved in neurulation, forms a novel chromatin remodeling complex with SNF2L

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

Epigenetic alterations in hematopoietic malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

Inactivating mutations of acetyltransferase genes in B-cell lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

Investigation of the acetylation mechanism by GCN5 histone acetyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

ATAD2B is a phylogenetically conserved nuclear protein expressed during neuronal differentiation and tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

MLL translocations, histone modifications and leukaemia stem-cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

Cloning and characterization of PHIP, a novel insulin receptor substrate-1 pleckstrin homology domain interacting protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

Germline nonsense mutation and somatic inactivation of SMARCA4/BRG1 in a family with rhabdoid tumor predisposition syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

SWI/SNF nucleosome remodellers and cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

Microarray comparative genomic hybridization detection of copy number changes in desmoplastic melanoma and malignant peripheral nerve sheath tumor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

Post-GWAS functional characterization of susceptibility variants for chronic lymphocytic leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

Functional substitution for TAF(II)250 by a retroposed homolog that is expressed in human spermatogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

The transcription coactivator HTIF1 and a related protein are fused to the RET receptor tyrosine kinase in childhood papillary thyroid carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

KAP-1, a novel corepressor for the highly conserved KRAB repression domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

TIF1delta, a novel HP1-interacting member of the transcriptional intermediary factor 1 (TIF1) family expressed by elongating spermatids

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

Expression of the Wdr9 gene and protein products during mouse development

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

The adenovirus E1A binding protein BS69 is a corepressor of transcription through recruitment of N-CoR

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

Fragment-based discovery of bromodomain inhibitors part 1: inhibitor binding modes and implications for lead discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

Selective small molecules blocking HIV-1 Tat and coactivator PCAF association

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

Target structure-based discovery of small molecules that block human p53 and CREB binding protein association

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

Suppression of inflammation by a synthetic histone mimic

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

Interaction of the bovine papillomavirus E2 protein with Brd4 tethers the viral DNA to host mitotic chromosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

The PAF complex synergizes with MLL fusion proteins at HOX loci to promote leukemogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

AFF4, a component of the ELL/P-TEFb elongation complex and a shared subunit of MLL chimeras, can link transcription elongation to leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

BET bromodomain inhibition as a therapeutic strategy to target c-Myc

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

Targeting MYC dependence in cancer by inhibiting BET bromodomains

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

8p11 myeloproliferative syndrome with a novel t(7;8) translocation leading to fusion of the FGFR1 and TIF1 genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

Prognostic significance of TRIM24/TIF-1α gene expression in breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

Trim24 targets endogenous p53 for degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

Negative control of Smad activity by ectodermin/Tif1gamma patterns the mammalian embryo

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

TRIM24 links a non-canonical histone signature to breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

Frequent BRG1/SMARCA4-inactivating mutations in human lung cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

Targeted knockout of BRG1 potentiates lung cancer development

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

Characterization of mammary tumors from Brg1 heterozygous mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

The CBP co-activator is a histone acetyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

Acetylation of HMG I(Y) by CBP turns off IFN beta expression by disrupting the enhanceosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

Recruitment of CBP/p300 by the IFN beta enhanceosome is required for synergistic activation of transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

Structural mechanism of the bromodomain of the coactivator CBP in p53 transcriptional activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

The translocation t(8;16)(p11;p13) of acute myeloid leukaemia fuses a putative acetyltransferase to the CREB-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

MOZ is fused to p300 in an acute monocytic leukemia with t(8;22).

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

The role of the transcriptional coactivator p300 in prostate cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

Transcriptional coactivators p300 and CBP stimulate estrogen receptor-beta signaling and regulate cellular events in prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

Small-molecule inhibition of BRDT for male contraception

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

Bromodomain-dependent stage-specific male genome programming by Brdt

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELT007

Inhibition of the acetyltransferases p300 and CBP reveals a targetable function for p300 in the survival and invasion pathways of prostate cancer cell lines

21 January 2018

1 reference

27 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1158/1535-7163.MCT-11-0182

Identifiers

DOI

10.1093/BFGP/ELT007

1 reference

28 August 2017

1 reference

PubMed ID

23543289