Therapeutic potential of serum and glucocorticoid inducible kinase inhibition (Q38090700)

28 August 2017

Therapeutic potential of serum and glucocorticoid inducible kinase inhibition (English)

1 reference

28 August 2017

Florian Lang

1

1 reference

PubMed ID

23506284

28 August 2017

Jakob Voelkl

series ordinal

2

1 reference

PubMed ID

23506284

28 August 2017

language of work or name

English

0 references

publication date

19 March 2013

1 reference

Expert Opinion on Investigational Drugs

28 August 2017

1 reference

28 August 2017

22

1 reference

28 August 2017

701-714

1 reference

28 August 2017

6

1 reference

Stimulus-dependent regulation of serum and glucocorticoid inducible protein kinase (SGK) transcription, subcellular localization and enzymatic activity

28 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Targeting SGK1 in diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Expression of the epithelial Na(+) channel and other components of an aldosterone response pathway in human adrenocortical cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

(Patho)physiological significance of the serum- and glucocorticoid-inducible kinase isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Deregulation of the serum- and glucocorticoid-inducible kinase SGK1 in the endometrium causes reproductive failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

A regulated NH2-terminal Sgk1 variant with enhanced function is expressed in the collecting duct.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Regulation of Orai1/STIM1 by the kinases SGK1 and AMPK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

The physiological impact of the serum and glucocorticoid-inducible kinase SGK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Heterocyclic indazole derivatives as SGK1 inhibitors, WO2008138448.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Colorectal carcinoma cells--regulation of survival and growth by SGK1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Adaptive variation regulates the expression of the human SGK1 gene in response to stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Interactions between glucocorticoid treatment and cis-regulatory polymorphisms contribute to cellular response phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Administration of glucocorticoids to ovarian cancer patients is associated with expression of the anti-apoptotic genes SGK1 and MKP1/DUSP1 in ovarian tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Opposite effects of serum- and glucocorticoid-regulated kinase-1 and glucocorticoids on POMC transcription and ACTH release

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Serine/threonine protein kinase SGK1 in glucocorticoid-dependent transdifferentiation of pancreatic acinar cells to hepatocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Mineralocorticoid receptor mutations differentially affect individual gene expression profiles in pseudohypoaldosteronism type 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Inhibition of AKT with the orally active allosteric AKT inhibitor, MK-2206, sensitizes endometrial cancer cells to progestin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Role of serum and glucocorticoid-regulated kinase-1 in the protective effects of erythropoietin during renal ischemia/reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Role of serum- and glucocorticoid-inducible kinase-1 in regulating torsion-induced apoptosis in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

miR133a regulates cardiomyocyte hypertrophy in diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Oxidative stress-induced glomerular mineralocorticoid receptor activation limits the benefit of salt reduction in Dahl salt-sensitive rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Hypertonicity increases sodium transporters in cortical collecting duct cells independently of PGE2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Role of mineralocorticoid receptor/Rho/Rho-kinase pathway in obesity-related renal injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Spironolactone improves nephropathy by enhancing glucose-6-phosphate dehydrogenase activity and reducing oxidative stress in diabetic hypertensive rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Effect of iron restriction on renal damage and mineralocorticoid receptor signaling in a rat model of chronic kidney disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

A nuclear complex of rictor and insulin receptor substrate-2 is associated with albuminuria in diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Advancing age is associated with gene expression changes resembling mTOR inhibition: evidence from two human populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Mitogen activated protein kinase 14-1 regulates serum glucocorticoid kinase 1 during seawater acclimation in Atlantic killifish, Fundulus heteroclitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Translational regulation of the serum- and glucocorticoid-inducible kinase-1 (SGK1) in platelets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Characterization of Rictor phosphorylation sites reveals direct regulation of mTOR complex 2 by S6K1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Androgen Receptor Enhances p27 Degradation in Prostate Cancer Cells through Rapid and Selective TORC2 Activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Serum and glucocorticoid-regulated kinase 1 (SGK1) activation in breast cancer: requirement for mTORC1 activity associates with ER-alpha expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Serum and glucocorticoid-induced kinase (SGK) 1 and the epithelial sodium channel are regulated by multiple with no lysine (WNK) family members

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Phospholipase D stabilizes HDM2 through an mTORC2/SGK1 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Protor-1 is required for efficient mTORC2-mediated activation of SGK1 in the kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

CDKs as therapeutic targets for the human genetic disease tuberous sclerosis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Rictor is a novel target of p70 S6 kinase-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Plasma corticosterone activates SGK1 and induces morphological changes in oligodendrocytes in corpus callosum

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Effect of Poria cocos on hypertonic stress-induced water channel expression and apoptosis in renal collecting duct cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Rictor forms a complex with Cullin-1 to promote SGK1 ubiquitination and destruction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Phosphorylation of Rictor at Thr1135 impairs the Rictor/Cullin-1 complex to ubiquitinate SGK1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Stimulation of ENaC activity by rosiglitazone is PPARγ-dependent and correlates with SGK1 expression increase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Glucocorticoid-induced Leucine zipper 1 stimulates the epithelial sodium channel by regulating serum- and glucocorticoid-induced kinase 1 stability and subcellular localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Hsp90 transcriptionally and post-translationally regulates the expression of NDRG1 and maintains the stability of its modifying kinase GSK3beta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Phosphorylation of NDRG1 is temporally and spatially controlled during the cell cycle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Transcription factor NF-κB regulates expression of pore-forming Ca2+ channel unit, Orai1, and its activator, STIM1, to control Ca2+ entry and affect cellular functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Protein kinase SGK1 enhances MEK/ERK complex formation through the phosphorylation of ERK2: implication for the positive regulatory role of SGK1 on the ERK function during liver regeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Serum- and glucocorticoid-inducible kinase 1 (SGK1) controls Notch1 signaling by downregulation of protein stability through Fbw7 ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Sgk1 activates MDM2-dependent p53 degradation and affects cell proliferation, survival, and differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Wnt signaling inhibits Forkhead box O3a-induced transcription and apoptosis through up-regulation of serum- and glucocorticoid-inducible kinase 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

The serum- and glucocorticoid-inducible kinase 1 (SGK1) influences platelet calcium signaling and function by regulation of Orai1 expression in megakaryocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Influence of dexamethasone on na+/h+ exchanger activity in dendritic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Aldosterone-stimulated SGK1 activity mediates profibrotic signaling in the mesangium

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Identification of sites subjected to serine/threonine phosphorylation by SGK1 affecting N-myc downstream-regulated gene 1 (NDRG1)/Cap43-dependent suppression of angiogenic CXC chemokine expression in human pancreatic cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Protein kinase B alpha (PKBα) stimulates the epithelial sodium channel (ENaC) heterologously expressed in Xenopus laevis oocytes by two distinct mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

COMMD1 downregulates the epithelial sodium channel through Nedd4-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Cholesterol depletion of the plasma membrane prevents activation of the epithelial sodium channel (ENaC) by SGK1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

mTOR complex-2 activates ENaC by phosphorylating SGK1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

mSIN1 protein mediates SGK1 protein interaction with mTORC2 protein complex and is required for selective activation of the epithelial sodium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

60kDa lysophospholipase, a new Sgk1 molecular partner involved in the regulation of ENaC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

SGK regulation of renal sodium transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Regulation of ENaC-Mediated Sodium Reabsorption by Peroxisome Proliferator-Activated Receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

AF17 competes with AF9 for binding to Dot1a to up-regulate transcription of epithelial Na+ channel alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Dot1a contains three nuclear localization signals and regulates the epithelial Na+ channel (ENaC) at multiple levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Scaffold protein connector enhancer of kinase suppressor of Ras isoform 3 (CNK3) coordinates assembly of a multiprotein epithelial sodium channel (ENaC)-regulatory complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Organization of the ENaC-regulatory machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

The role of the ENaC-regulatory complex in aldosterone-mediated sodium transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Epithelial sodium channel regulation by cell surface-associated serum- and glucocorticoid-regulated kinase 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Epithelial Na⁺ channel activity in human airway epithelial cells: the role of serum and glucocorticoid-inducible kinase 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

The neuronal-specific SGK1.1 kinase regulates {delta}-epithelial Na+ channel independently of PY motifs and couples it to phospholipase C signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Interaction of serum- and glucocorticoid regulated kinase 1 (SGK1) with the WW-domains of Nedd4-2 is required for epithelial sodium channel regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Activation of PI3-kinase stimulates endocytosis of ROMK via Akt1/SGK1-dependent phosphorylation of WNK1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Protein phosphatase 1 modulates the inhibitory effect of With-no-Lysine kinase 4 on ROMK channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Src family protein tyrosine kinase (PTK) modulates the effect of SGK1 and WNK4 on ROMK channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Angiotensin II diminishes the effect of SGK1 on the WNK4-mediated inhibition of ROMK1 channels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Up-regulation of serum- and glucocorticoid-induced protein kinase 1 in the brain tissue of human and experimental epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Long QT syndrome-associated mutations in KCNQ1 and KCNE1 subunits disrupt normal endosomal recycling of IKs channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Serum- and glucocorticoid-inducible kinases (SGK) regulate KCNQ1/KCNE potassium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Stimulation of Ca2+-channel Orai1/STIM1 by serum- and glucocorticoid-inducible kinase 1 (SGK1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Phosphorylation on the Ser 824 residue of TRPV4 prefers to bind with F-actin than with microtubules to expand the cell surface area

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Rescue of DeltaF508-CFTR by the SGK1/Nedd4-2 signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

PIKfyve upregulates CFTR activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Morpholino gene knockdown in adult Fundulus heteroclitus: role of SGK1 in seawater acclimation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Arsenic inhibits SGK1 activation of CFTR Cl- channels in the gill of killifish, Fundulus heteroclitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Nedd4-2 modulates renal Na+-Cl- cotransporter via the aldosterone-SGK1-Nedd4-2 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Nedd4-2 and the regulation of epithelial sodium transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Aldosterone mediates activation of the thiazide-sensitive Na-Cl cotransporter through an SGK1 and WNK4 signaling pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Expression and phosphorylation of the Na+-Cl- cotransporter NCC in vivo is regulated by dietary salt, potassium, and SGK1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Sgk1 sensitivity of Na(+)/H(+) exchanger activity and cardiac remodeling following pressure overload.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

NHE3 function and phosphorylation are regulated by a calyculin A-sensitive phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Serum- and glucocorticoid-induced kinase 3 in recycling endosomes mediates acute activation of Na+/H+ exchanger NHE3 by glucocorticoids

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Renal epidermal growth factor receptor: its role in sodium and water homeostasis in diabetic nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Expression and role of serum and glucocorticoid-regulated kinase 2 in the regulation of Na+/H+ exchanger 3 in the mammalian kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

SGK1-dependent stimulation of intestinal SGLT1 activity by vitamin D.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

The serum and glucocorticoid inducible kinases SGK1-3 stimulate the neutral amino acid transporter SLC6A19.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Regulation of the glutamate transporter EAAT2 by PIKfyve

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Regulation of the Na(+)-coupled glutamate transporter EAAT3 by PIKfyve.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Regulation of the glutamate transporter EAAT4 by PIKfyve

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Stimulation of electrogenic intestinal dipeptide transport by the glucocorticoid dexamethasone

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

PI3 kinase and PDK1 in the regulation of the electrogenic intestinal dipeptide transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

FGF23 acts directly on renal proximal tubules to induce phosphaturia through activation of the ERK1/2-SGK1 signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Neural precursor cell-expressed developmentally down-regulated protein 4-2 (Nedd4-2) regulation by 14-3-3 protein binding at canonical serum and glucocorticoid kinase 1 (SGK1) phosphorylation sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Dexamethasone increases the phosphorylation of nephrin in cultured podocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Simulated bladder pressure stimulates human bladder smooth muscle cell proliferation via the PI3K/SGK1 signaling pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

IL-2 signals through Sgk1 and inhibits proliferation and apoptosis in kidney cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Serum- and glucocorticoid-dependent kinase-1-induced cell migration is dependent on vinculin and regulated by the membrane androgen receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Serum- and glucocorticoid-inducible kinase 1 in the regulation of renal and extrarenal potassium transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Inducible kidney-specific Sgk1 knockout mice show a salt-losing phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Role of PDK1 in regulation of gastric acid secretion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Pioglitazone induced gastric acid secretion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Responses to diuretic treatment in gene-targeted mice lacking serum- and glucocorticoid-inducible kinase 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Hyperaldosteronism, hypervolemia, and increased blood pressure in mice expressing defective APC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Hyperaldosteronism and altered expression of an SGK1-dependent sodium transporter in ZDF rats leads to salt dependence of blood pressure

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Serum/glucocorticoid-induced protein kinase-1 facilitates androgen receptor-dependent cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Activation of mineralocorticoid receptors in the rostral ventrolateral medulla is involved in hypertensive mechanisms in stroke-prone spontaneously hypertensive rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Serum- and glucocorticoid-inducible kinase 1 (SGK1) regulates adipocyte differentiation via forkhead box O1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Genetic variants in serum and glucocortocoid regulated kinase 1, a regulator of the epithelial sodium channel, are associated with ischaemic stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Ubiquitin ligase Nedd4L targets activated Smad2/3 to limit TGF-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Serum- and glucocorticoid-regulated kinase 1 is upregulated following unilateral ureteral obstruction causing epithelial-mesenchymal transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Peritoneal mesothelial cells as a target of local aldosterone action: upregulation of connective tissue growth factor expression via serum- and glucocorticoid-inducible protein kinase 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Increased expression of serum- and glucocorticoid-regulated kinase-1 in the duodenal mucosa of children with coeliac disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Direct aldosterone action as a profibrotic factor via ROS-mediated SGK1 in peritoneal fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

SGK1-mediated fibronectin formation in diabetic nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Pathological role of serum- and glucocorticoid-regulated kinase 1 in adverse ventricular remodeling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Cross talk between corticosteroids and alpha-adrenergic signalling augments cardiomyocyte hypertrophy: a possible role for SGK1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Serum/glucocorticoid-regulated kinase 1 (SGK1) is a prominent target gene of the transcriptional response to cytokines in multiple myeloma and supports the growth of myeloma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Defining a role for Sonic hedgehog pathway activation in desmoplastic medulloblastoma by identifying GLI1 target genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Serum/glucocorticoid-regulated kinase 1 expression in primary human prostate cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Determination of SGK1 mRNA in non-small cell lung cancer samples underlines high expression in squamous cell carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Angiotensin II mediates cell survival through upregulation and activation of the serum and glucocorticoid inducible kinase 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Androgen-induced coactivator ANCCA mediates specific androgen receptor signaling in prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Functional membrane androgen receptors in colon tumors trigger pro-apoptotic responses in vitro and reduce drastically tumor incidence in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Membrane androgen receptor activation triggers down-regulation of PI-3K/Akt/NF-kappaB activity and induces apoptotic responses via Bad, FasL and caspase-3 in DU145 prostate cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Single nucleotide polymorphism microarray analysis in cortisol-secreting adrenocortical adenomas identifies new candidate genes and pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Putative direct and indirect Wnt targets identified through consistent gene expression changes in APC-mutant intestinal adenomas from humans and mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Relative resistance of SGK1 knockout mice against chemical carcinogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Impaired mast cell activation in gene-targeted mice lacking the serum- and glucocorticoid-inducible kinase SGK1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Effects of nominally selective inhibitors of the kinases PI3K, SGK1 and PKB on the insulin-dependent control of epithelial Na+ absorption

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Dysregulation of epithelial Na+ absorption induced by inhibition of the kinases TORC1 and TORC2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Glucocorticoids can activate the alpha-ENaC gene promoter independently of SGK1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Effects of peroxisome proliferator-activated receptor gamma agonists on Na+ transport and activity of the kinase SGK1 in epithelial cells from lung and kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Regulation of ENaC-mediated alveolar fluid clearance by insulin via PI3K/Akt pathway in LPS-induced acute lung injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Insulin up-regulates epithelial sodium channel in LPS-induced acute lung injury model in rats by SGK1 activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Serum and glucocorticoid-inducible kinase 1 (SGK1) is necessary for vascular remodeling during angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

The dissection of transcriptional modules regulated by various drugs of abuse in the mouse striatum

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Spinal SGK1/GRASP-1/Rab4 is involved in complete Freund's adjuvant-induced inflammatory pain via regulating dorsal horn GluR1-containing AMPA receptor trafficking in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Significance of SGK1 in the regulation of neuronal function

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

SGK protein kinase facilitates the expression of long-term potentiation in hippocampal neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Laminin-β1 impairs spatial learning through inhibition of ERK/MAPK and SGK1 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Up-regulation of glucocorticoid-regulated genes in a mouse model of Rett syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Phosphorylation of nicastrin by SGK1 leads to its degradation through lysosomal and proteasomal pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

A novel defense mechanism that is activated on amyloid-beta insult to mediate cell survival: role of SGK1-STAT1/STAT2 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

The serum- and glucocorticoid-induced kinase SGK inhibits mutant huntingtin-induced toxicity by phosphorylating serine 421 of huntingtin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

sgk1, a member of an RNA cluster associated with cell death in a model of Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Gene expression profiling in the midbrain of striatal 6-hydroxydopamine-injected mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Serum- and glucocorticoid-regulated kinase (SGK1) gene and blood pressure

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Genetic variance of SGK-1 is associated with blood pressure, blood pressure change over time and strength of the insulin-diastolic blood pressure relationship.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Variance of the SGK1 gene is associated with insulin secretion in different European populations: results from the TUEF, EUGENE2, and METSIM studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Development of a small-molecule serum- and glucocorticoid-regulated kinase-1 antagonist and its evaluation as a prostate cancer therapeutic.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

EMD638683, a novel SGK inhibitor with antihypertensive potency.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Design and synthesis of orally bioavailable serum and glucocorticoid-regulated kinase 1 (SGK1) inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Altered synaptic physiology and reduced susceptibility to kainate-induced seizures in GluR6-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Serum- and glucocorticoid-inducible kinase 1 (SGK1) increases neurite formation through microtubule depolymerization by SGK1 and by SGK1 phosphorylation of tau

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

IL-6 activates serum and glucocorticoid kinase via p38alpha mitogen-activated protein kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

Microarray analysis reveals glucocorticoid-regulated survival genes that are associated with inhibition of apoptosis in breast epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

SGK1, a potential regulator of c-fms related breast cancer aggressiveness

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.778971

10.1517/13543784.2013.778971

21 January 2018

Identifiers

DOI

1 reference

28 August 2017

1 reference

PubMed ID

23506284