The role of the CXCR4 cell surface chemokine receptor in glioma biology (Q38089686)

28 August 2017

The role of the CXCR4 cell surface chemokine receptor in glioma biology (English)

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28 August 2017

Moneeb Ehtesham

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28 August 2017

Elliot Min

2

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28 August 2017

Neil M Issar

3

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28 August 2017

Rebecca A Kasl

4

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28 August 2017

Imad S Khan

5

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28 August 2017

Reid C Thompson

6

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28 August 2017

14 March 2013

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Journal of Neuro-Oncology

28 August 2017

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28 August 2017

113

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28 August 2017

2

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28 August 2017

153-162

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https://scigraph.springernature.com/pub.10.1007/s11060-013-1108-4

28 August 2017

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Glioblastoma-derived tumorospheres identify a population of tumor stem-like cells with angiogenic potential and enhanced multidrug resistance phenotype.

21 January 2018

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CXCR4 mediates the proliferation of glioblastoma progenitor cells

21 January 2018

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Involvement of chemokine receptors in breast cancer metastasis

21 January 2018

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Chemosensitization of acute myeloid leukemia (AML) following mobilization by the CXCR4 antagonist AMD3100.

21 January 2018

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CXCR4 expression mediates glioma cell invasiveness

21 January 2018

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CXCR4 expression is elevated in glioblastoma multiforme and correlates with an increase in intensity and extent of peritumoral T2-weighted magnetic resonance imaging signal abnormalities

21 January 2018

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CXCR4 is a major chemokine receptor on glioma cells and mediates their survival.

21 January 2018

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Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists

21 January 2018

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CXCL12 (SDF-1)/CXCR4 pathway in cancer

21 January 2018

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Expression and functional characterization of mutant human CXCR4 in insect cells: role of cysteinyl and negatively charged residues in ligand binding

21 January 2018

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Structural Basis of CXCR4 Sulfotyrosine Recognition by the Chemokine SDF-1/CXCL12

21 January 2018

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Solution structure and basis for functional activity of stromal cell-derived factor-1; dissociation of CXCR4 activation from binding and inhibition of HIV-1.

21 January 2018

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Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice

21 January 2018

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Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development

21 January 2018

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Abnormal development of the hippocampal dentate gyrus in mice lacking the CXCR4 chemokine receptor

21 January 2018

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Stromal-derived factor-1 (CXCL12) regulates laminar position of Cajal-Retzius cells in normal and dysplastic brains

21 January 2018

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The chemokine stromal cell-derived factor-1 regulates GABAergic inputs to neural progenitors in the postnatal dentate gyrus.

21 January 2018

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CXCL12 increases human neural progenitor cell proliferation through Akt-1/FOXO3a signaling pathway

21 January 2018

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Role of the intracellular domains of CXCR4 in SDF-1-mediated signaling

21 January 2018

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SDF-1alpha up-regulates interleukin-6 through CXCR4, PI3K/Akt, ERK, and NF-kappaB-dependent pathway in microglia.

21 January 2018

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21 January 2018

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CXCL12 / CXCR4 / CXCR7 chemokine axis and cancer progression

21 January 2018

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CXCR4-SDF-1 signaling is active in rhabdomyosarcoma cells and regulates locomotion, chemotaxis, and adhesion.

21 January 2018

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Heterologous cells cooperate to augment stem cell migration, homing, and engraftment.

21 January 2018

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Chemokines and the arrest of lymphocytes rolling under flow conditions.

21 January 2018

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Functional expression of CXCR4 (CD184) on small-cell lung cancer cells mediates migration, integrin activation, and adhesion to stromal cells.

21 January 2018

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CXCR4-mediated adhesion and MMP-9 secretion in head and neck squamous cell carcinoma

21 January 2018

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Skeletal localization and neutralization of the SDF-1(CXCL12)/CXCR4 axis blocks prostate cancer metastasis and growth in osseous sites in vivo.

21 January 2018

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A CXCR4 antagonist CTCE-9908 inhibits primary tumor growth and metastasis of breast cancer

21 January 2018

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Phenotypic knockout of CXCR4 by a novel recombinant protein TAT/54R/KDEL inhibits tumors metastasis.

21 January 2018

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Butein downregulates chemokine receptor CXCR4 expression and function through suppression of NF-κB activation in breast and pancreatic tumor cells.

21 January 2018

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Effects of CXCR4 antagonist CTCE-9908 on prostate tumor growth

21 January 2018

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The WHO classification of tumors of the nervous system

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11060-013-1108-4

A small-molecule antagonist of CXCR4 inhibits intracranial growth of primary brain tumors.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11060-013-1108-4

The hypoxic response: huffing and HIFing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-013-1108-4

Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1

21 January 2018

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Chemokine receptor CXCR4 downregulated by von Hippel-Lindau tumour suppressor pVHL.

21 January 2018

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Expression of hypoxia-inducible factor 1? in brain tumors

21 January 2018

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Hypoxia-inducible factor 1 and VEGF upregulate CXCR4 in glioblastoma: implications for angiogenesis and glioma cell invasion

21 January 2018

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Expression of stem cell markers in human astrocytomas of different WHO grades.

21 January 2018

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CXCR4 inhibition synergizes with cytotoxic chemotherapy in gliomas.

21 January 2018

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The chemokine CXCL12 and its receptor CXCR4 promote glioma stem cell-mediated VEGF production and tumour angiogenesis via PI3K/AKT signalling.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11060-013-1108-4

Preferential expression of chemokine receptor CXCR4 by highly malignant human gliomas and its association with poor patient survival

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11060-013-1108-4

Increased survival, proliferation, and migration in metastatic human pancreatic tumor cells expressing functional CXCR4.

21 January 2018

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Zerumbone down-regulates chemokine receptor CXCR4 expression leading to inhibition of CXCL12-induced invasion of breast and pancreatic tumor cells

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11060-013-1108-4

Inhibition of CXCR4 activity with AMD3100 decreases invasion of human colorectal cancer cells in vitro

21 January 2018

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Inhibition of the CXCR4/CXCL12 chemokine pathway reduces the development of murine pulmonary metastases

21 January 2018

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Blocking CXCR4-mediated cyclic AMP suppression inhibits brain tumor growth in vivo

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11060-013-1108-4

CXCR-4, a chemokine receptor, is overexpressed in and required for proliferation of glioblastoma tumor cells.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11060-013-1108-4

Identification and localization of the cytokine SDF1 and its receptor, CXC chemokine receptor 4, to regions of necrosis and angiogenesis in human glioblastoma.

21 January 2018

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12 December 2020

The chemokine SDF1 regulates migration of dentate granule cells

1 reference

12 December 2020

Stromal cell-derived factor 1alpha stimulates human glioblastoma cell growth through the activation of both extracellular signal-regulated kinases 1/2 and Akt

1 reference

12 December 2020

Preferential expression of chemokine receptor CXCR4 by highly malignant human gliomas and its association with poor patient survival

1 reference

12 December 2020

Regulation of cellular proliferation, cytoskeletal function, and signal transduction through CXCR4 and c-Kit in small cell lung cancer cells

1 reference

12 December 2020

Blockade of CXCR4 in oral squamous cell carcinoma inhibits lymph node metastases

1 reference

12 December 2020

T140 analogs as CXCR4 antagonists identified as anti-metastatic agents in the treatment of breast cancer

1 reference

12 December 2020

RNA interference as a plausible anticancer therapeutic tool

1 reference

12 December 2020

CXCR4 chemokine receptor antagonists: perspectives in SCLC

1 reference

12 December 2020

CXCR4 regulates interneuron migration in the developing neocortex.

1 reference

12 December 2020

The chemokine receptor CXCR4 is required for outgrowth of colon carcinoma micrometastases

1 reference

12 December 2020

Inhibition of CXCR4 by CTCE-9908 inhibits breast cancer metastasis to lung and bone.

1 reference

12 December 2020

Expression of hypoxia-inducible factor 1alpha in brain tumors: association with angiogenesis, invasion, and progression

1 reference

12 December 2020

Use of the stromal cell-derived factor-1/CXCR4 pathway in prostate cancer metastasis to bone

1 reference

12 December 2020

10.1007/S11060-013-1108-4

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DOI

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Dimensions Publication ID

28 August 2017

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