Review of the alterations in DNA methylation in esophageal squamous cell carcinoma (Q38071897)

28 August 2017

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title

Review of the alterations in DNA methylation in esophageal squamous cell carcinoma (English)

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esophageal squamous cell carcinoma

28 August 2017

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Yoshifumi Baba

1

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PubMed ID

23291904

28 August 2017

Masayuki Watanabe

series ordinal

2

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PubMed ID

23291904

28 August 2017

Hideo Baba

series ordinal

3

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28 August 2017

5 January 2013

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28 August 2017

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28 August 2017

43

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28 August 2017

12

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28 August 2017

1355-1364

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The role of epigenetic transcription repression and DNA methyltransferases in cancer.

28 August 2017

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https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

Epigenetic modifications and human disease

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

Cancer epigenetics reaches mainstream oncology

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

The impact of retrotransposons on human genome evolution

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

The power and the promise of DNA methylation markers

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

DNA hypomethylation in cancer cells

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

Mammalian DNA methyltransferases: a structural perspective

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

High frequency mutagenesis by a DNA methyltransferase

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

DNA methylation, methyltransferases, and cancer

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

Cancer epigenetics comes of age

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

Hypomethylation distinguishes genes of some human cancers from their normal counterparts

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

Induction of Tumors in Mice by Genomic Hypomethylation

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

APC, signal transduction and genetic instability in colorectal cancer

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

Loss of heterozygosity involving the APC and MCC genetic loci occurs in the majority of human esophageal cancers

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

Qualitative analysis of Adenomatous Polyposis Coli promoter: hypermethylation, engagement and effects on survival of patients with esophageal cancer in a high risk region of the world, a potential molecular marker.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

Oesophageal squamous cell carcinoma may develop within a background of accumulating DNA methylation in normal and dysplastic mucosa

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

Cell adhesion and signalling by cadherins and Ig-CAMs in cancer

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

Expression of vascular endothelial growth factor, matrix metalloproteinase-9 and E-cadherin in the process of lymph node metastasis in oesophageal cancer

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

CpG island hypermethylation of E-cadherin (CDH1) and integrin alpha4 is associated with recurrence of early stage esophageal squamous cell carcinoma

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

E-cadherin expression is commonly downregulated by CpG island hypermethylation in esophageal carcinoma cells

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

The INK4a/ARF network in tumour suppression

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

Low frequency of p16/CDKN2 gene mutations in esophageal carcinomas

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

Aberrant methylation of p16INK4a and deletion of p15INK4b are frequent events in human esophageal cancer in Linxian, China.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

Aberrant DNA methylation of P16, MGMT, and hMLH1 genes in combination with MTHFR C677T genetic polymorphism in esophageal squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

CpG island methylator phenotype of cell-cycle regulators associated with TNM stage and poor prognosis in patients with oesophageal squamous cell carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

Hypermethylation of multiple tumor-related genes associated with DNMT3b up-regulation served as a biomarker for early diagnosis of esophageal squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

p16INK4a hypermethylation and p53, p16 and MDM2 protein expression in esophageal squamous cell carcinoma

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

Aberrant promoter methylation and reduced expression of p16 gene in esophageal squamous cell carcinoma from Kashmir valley: a high-risk area.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

Detection of multiple gene hypermethylation in the development of esophageal squamous cell carcinoma

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

Reduced acetylated histone H4 is associated with promoter methylation of the fragile histidine triad gene in resected esophageal squamous cell carcinoma.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

Nicotine induces the fragile histidine triad methylation in human esophageal squamous epithelial cells.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

RASSF1A gene promoter methylation in esophageal cancer specimens.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

Hypermethylation-modulated downregulation of RASSF1A expression is associated with the progression of esophageal cancer

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

Frequent loss of heterozygosity but rare microsatellite instability in oesophageal cancer in Japanese and Chinese patients.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

Microsatellite instability in esophageal squamous cell carcinoma is not associated with hMLH1 promoter hypermethylation

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

Microsatellite alterations in esophageal dysplasia and squamous cell carcinoma from laser capture microdissected endoscopic biopsies

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

Promoter methylation of the hMLH1 gene and protein expression of human mutL homolog 1 and human mutS homolog 2 in resected esophageal squamous cell carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

Aberrant methylation of different DNA repair genes demonstrates distinct prognostic value for esophageal cancer

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

MGMT: its role in cancer aetiology and cancer therapeutics

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

Epigenetic deregulation of DNA repair and its potential for therapy

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

Inactivation of DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation and its relation to p53 mutations in esophageal squamous cell carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

Aberrant methylation of the 3q25 tumor suppressor gene PTX3 in human esophageal squamous cell carcinoma

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

Epigenetic inactivation of the SFRP1 gene in esophageal squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

The ECM protein LTBP-2 is a suppressor of esophageal squamous cell carcinoma tumor formation but higher tumor expression associates with poor patient outcome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

Low expression of claudin-4 is associated with poor prognosis in esophageal squamous cell carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

Frequent silencing of protocadherin 17, a candidate tumour suppressor for esophageal squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

Promoter methylation of HIN-1 in the progression to esophageal squamous cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

Aberrant promoter methylation of the TPEF gene in esophageal squamous cell carcinoma

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

Methylation of TIMP3 in esophageal squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

Identification of an invasion and tumor-suppressing gene, Endoglin (ENG), silenced by both epigenetic inactivation and allelic loss in esophageal squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

The role of PGP9.5 as a tumor suppressor gene in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

PGP9.5 promoter methylation is an independent prognostic factor for esophageal squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

Promoter hypermethylation of the RUNX3 gene in esophageal squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

DCC promoter hypermethylation in esophageal squamous cell carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

HOP/OB1/NECC1 promoter DNA is frequently hypermethylated and involved in tumorigenic ability in esophageal squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

A promoter methylation pattern in the N-methyl-D-aspartate receptor 2B gene predicts poor prognosis in esophageal squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

Hypermethylation of the somatostatin promoter is a common, early event in human esophageal carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

Hypermethylation of tachykinin-1 is a potential biomarker in human esophageal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

p300 expression repression by hypermethylation associated with tumour invasion and metastasis in oesophageal squamous cell carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

Epigenetic silencing of CDX2 is a feature of squamous esophageal cancer

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

Frequent methylation-associated silencing of a candidate tumor-suppressor, CRABP1, in esophageal squamous-cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

Metallothionien 3 expression is frequently down-regulated in oesophageal squamous cell carcinoma by DNA methylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

DNA methylation of genes linked to retinoid signaling in squamous cell carcinoma of the esophagus: DNA methylation of CRBP1 and TIG1 is associated with tumor stage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

Frequent silencing of low density lipoprotein receptor-related protein 1B (LRP1B) expression by genetic and epigenetic mechanisms in esophageal squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

Chfr expression is downregulated by CpG island hypermethylation in esophageal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

Epigenetics and genetics. MicroRNAs en route to the clinic: progress in validating and targeting microRNAs for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

MicroRNA-21 regulates the proliferation and invasion in esophageal squamous cell carcinoma.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

Overexpression of microRNA-223 regulates the ubiquitin ligase FBXW7 in oesophageal squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

CpG island methylation status of miRNAs in esophageal squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

Epigenetic silencing of microRNA-375 regulates PDK1 expression in esophageal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

MicroRNA-375 inhibits tumour growth and metastasis in oesophageal squamous cell carcinoma through repressing insulin-like growth factor 1 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

Phase I study of decitabine-mediated gene expression in patients with cancers involving the lungs, esophagus, or pleura

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

Impact on DNA methylation in cancer prevention and therapy by bioactive dietary components

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

Reversal of hypermethylation and reactivation of p16INK4a, RARbeta, and MGMT genes by genistein and other isoflavones from soy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00595-012-0451-Y

Chromosomal Instability and Tumors Promoted by DNA Hypomethylation

21 January 2018

1 reference

12 December 2020

Frequent silencing of RUNX3 in esophageal squamous cell carcinomas is associated with radioresistance and poor prognosis

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12 December 2020

[Detection of methylation of hMSH2 gene promoter region of esophageal cancer]

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12 December 2020

Aberrant promoter hypermethylation and silencing of the critical 3p21 tumour suppressor gene, RASSF1A, in Chinese oesophageal squamous cell carcinoma

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12 December 2020

Associations of risk factors obesity and occupational airborne exposures with CDKN2A/p16 aberrant DNA methylation in esophageal cancer patients

1 reference

12 December 2020

Decreased expression of RUNX3 is correlated with tumor progression and poor prognosis in patients with esophageal squamous cell carcinoma.

1 reference

12 December 2020

Tea polyphenol (-)-epigallocatechin-3-gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines.

1 reference

12 December 2020

Quantitative detection of TIMP-3 promoter hypermethylation and its prognostic significance in esophageal squamous cell carcinoma.

1 reference

12 December 2020

Inactivation of the CDKN2 gene by homozygous deletion and de novo methylation is associated with advanced stage esophageal squamous cell carcinoma

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12 December 2020

APC gene mutations in the mutation cluster region are rare in esophageal cancers.

1 reference

12 December 2020

Microsatellite instability in Japanese esophageal carcinoma

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12 December 2020

Regulation of Cdx2 expression by promoter methylation, and effects of Cdx2 transfection on morphology and gene expression of human esophageal epithelial cells

1 reference

12 December 2020

Accumulation of promoter methylation suggests epigenetic progression in squamous cell carcinoma of the esophagus

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12 December 2020

Allele loss and promoter hypermethylation of VHL, RAR-beta, RASSF1A, and FHIT tumor suppressor genes on chromosome 3p in esophageal squamous cell carcinoma

1 reference

12 December 2020

Aberrant promoter CpG island hypermethylation of the adenomatosis polyposis coli gene can serve as a good prognostic factor by affecting lymph node metastasis in squamous cell carcinoma of the esophagus

1 reference

12 December 2020

Microsatellite instability in squamous cell carcinomas and dysplasias of the esophagus.

1 reference

12 December 2020

Aberrant methylation of Fragile Histidine Triad gene is associated with poor prognosis in early stage esophageal squamous cell carcinoma

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12 December 2020

Promoter methylation of heat shock protein B2 in human esophageal squamous cell carcinoma

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12 December 2020

Pyrosequencing assay to measure LINE-1 methylation level in esophageal squamous cell carcinoma

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12 December 2020

Methylation of the 5' CpG island of the FHIT gene is closely associated with transcriptional inactivation in esophageal squamous cell carcinomas

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12 December 2020

Aberrations of tumor-suppressor genes (p53, apc, mcc and Rb) in esophageal squamous-cell carcinoma

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12 December 2020

Microsatellite instability and clinicopathological features in esophageal squamous cell cancer.

1 reference

12 December 2020

p16, MGMT, RARbeta2, CLDN3, CRBP and MT1G gene methylation in esophageal squamous cell carcinoma and its precursor lesions.

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12 December 2020

Promoter hypermethylation of RASSF1A in esophageal squamous cell carcinoma

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12 December 2020

Aberrant methylation is frequently observed in advanced esophageal squamous cell carcinoma

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12 December 2020

Involvement of TSLC1 in progression of esophageal squamous cell carcinoma

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12 December 2020

Downregulation of retinoic acid receptor-beta(2) expression is linked to aberrant methylation in esophageal squamous cell carcinoma cell lines.

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12 December 2020

DNA methylation regulates MicroRNA expression

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12 December 2020

Esophageal squamous cell carcinomas with DNA replication errors (RER+) are associated with p16/pRb loss and wild-type p53

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12 December 2020

Differential expression of RUNX genes in human esophageal squamous cell carcinoma: downregulation of RUNX3 worsens patient prognosis

1 reference

12 December 2020

Hypermethylation-associated inactivation of retinoic acid receptor beta in human esophageal squamous cell carcinoma

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12 December 2020

E-cadherin expression in patients with esophageal squamous cell carcinoma: promoter hypermethylation, Snail overexpression, and clinicopathologic implications

1 reference

12 December 2020

Promoter hypermethylation and inactivation of O(6)-methylguanine-DNA methyltransferase in esophageal squamous cell carcinomas and its reactivation in cell lines.

1 reference

12 December 2020

Mechanisms of inactivation of p14ARF, p15INK4b, and p16INK4a genes in human esophageal squamous cell carcinoma

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12 December 2020

Frequent loss of heterozygosity on chromosome 9 in adenocarcinoma and squamous cell carcinoma of the esophagus.

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12 December 2020

Modes of silencing of p16 in development of esophageal squamous cell carcinoma

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12 December 2020

1 reference

12 December 2020

Methylation-mediated gene silencing of suppressor of cytokine signaling-1 (SOCS-1) gene in esophageal squamous cell carcinoma patients of Kashmir valley

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12 December 2020

Microsatellite instability analysis and its correlation with hMLH1 repair gene hypermethylation status in esophageal pathologies including cancers.

1 reference

12 December 2020

DNA methylation and loss of protein expression in esophageal squamous cell carcinogenesis of high-risk area.

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12 December 2020

LINE-1 hypomethylation is associated with a poor prognosis among patients with curatively resected esophageal squamous cell carcinoma

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12 December 2020

10.1007/S00595-012-0451-Y

Identifiers

DOI

1 reference

28 August 2017

1 reference

PubMed ID

23291904