Recent updates on the development of ganetespib as a Hsp90 inhibitor (Q38065103)

28 August 2017

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title

Recent updates on the development of ganetespib as a Hsp90 inhibitor (English)

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28 August 2017

Hyun Kyung Choi

1

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28 August 2017

Kyeong Lee

series ordinal

2

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28 August 2017

publication date

1 November 2012

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Archives of Pharmacal Research

28 August 2017

published in

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28 August 2017

volume

35

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28 August 2017

issue

11

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28 August 2017

page(s)

1855-1859

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https://scigraph.springernature.com/pub.10.1007/s12272-012-1101-z

28 August 2017

exact match

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cites work

The Clinical Applications of Heat Shock Protein Inhibitors in Cancer - Present and Future

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Phase I pharmacokinetic and pharmacodynamic study of 17-allylamino, 17-demethoxygeldanamycin in patients with advanced malignancies

21 January 2018

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Heat shock protein 90: inhibitors in clinical trials.

21 January 2018

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The identification, synthesis, protein crystal structure and in vitro biochemical evaluation of a new 3,4-diarylpyrazole class of Hsp90 inhibitors

21 January 2018

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Novel, potent small-molecule inhibitors of the molecular chaperone Hsp90 discovered through structure-based design

21 January 2018

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Regulation of Hsp90 client proteins by a Cullin5-RING E3 ubiquitin ligase

21 January 2018

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Phase I and pharmacologic study of 17-(allylamino)-17-demethoxygeldanamycin in adult patients with solid tumors.

21 January 2018

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A phase II trial of 17-allylamino-17-demethoxygeldanamycin in patients with hormone-refractory metastatic prostate cancer

21 January 2018

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Update on Hsp90 inhibitors in clinical trial.

21 January 2018

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The novel HSP90 inhibitor STA-9090 exhibits activity against Kit-dependent and -independent malignant mast cell tumors

21 January 2018

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Evaluation of 8-arylsulfanyl, 8-arylsulfoxyl, and 8-arylsulfonyl adenine derivatives as inhibitors of the heat shock protein 90.

21 January 2018

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The novel HSP90 inhibitor STA-1474 exhibits biologic activity against osteosarcoma cell lines

21 January 2018

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Structure and mechanism of the Hsp90 molecular chaperone machinery

21 January 2018

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Targeting of multiple signalling pathways by heat shock protein 90 molecular chaperone inhibitors

21 January 2018

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Functional specificity of co-chaperone interactions with Hsp90 client proteins.

21 January 2018

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HSP90 at the hub of protein homeostasis: emerging mechanistic insights

21 January 2018

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Targeting the dynamic HSP90 complex in cancer

21 January 2018

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Targeting wide-range oncogenic transformation via PU24FCl, a specific inhibitor of tumor Hsp90.

21 January 2018

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Ganetespib, a unique triazolone-containing Hsp90 inhibitor, exhibits potent antitumor activity and a superior safety profile for cancer therapy

21 January 2018

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Combinatorial attack on multistep oncogenesis by inhibiting the Hsp90 molecular chaperone

21 January 2018

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Targeting the molecular chaperone heat shock protein 90 provides a multifaceted effect on diverse cell signaling pathways of cancer cells

21 January 2018

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10.1007/S12272-012-1101-Z

21 January 2018

Identifiers

DOI

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Dimensions Publication ID

28 August 2017

1031090570

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