Terpenoids: natural products for cancer therapy (Q38054798)

27 August 2017

Terpenoids: natural products for cancer therapy (English)

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27 August 2017

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2

Jin-Jian Lu

1 reference

27 August 2017

Min Huang

1

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27 August 2017

Ming-Qing Huang

3

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27 August 2017

Jiao-Lin Bao

4

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27 August 2017

Xiu-Ping Chen

5

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27 August 2017

Yi-Tao Wang

6

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27 August 2017

language of work or name

English

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publication date

23 October 2012

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Expert Opinion on Investigational Drugs

27 August 2017

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27 August 2017

21

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27 August 2017

12

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27 August 2017

1801-1818

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Natural products as sources of new drugs over the period 1981-2002.

27 August 2017

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https://api.crossref.org/works/10.1517%2F13543784.2012.727395

The function of terpene natural products in the natural world

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Triterpenoids as new promising anticancer drugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

d -Limonene sensitizes docetaxel-induced cytotoxicity in human prostate cancer cells: Generation of reactive oxygen species and induction of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Modulation of the mevalonate pathway and cell growth by pravastatin and d-limonene in a human hepatoma cell line (Hep G2)

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Inhibition by d-limonene of experimental hepatocarcinogenesis in Sprague-Dawley rats does not involve p21(ras) plasma membrane association

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Induction of apoptosis by d-limonene is mediated by a caspase-dependent mitochondrial death pathway in human leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

The effects of cantharidin and cantharidin derivates on tumour cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Anhydride modified cantharidin analogues: synthesis, inhibition of protein phosphatases 1 and 2A and anticancer activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Effector mechanisms of norcantharidin-induced mitotic arrest and apoptosis in human hepatoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Cantharidin-induced cytotoxicity and cyclooxygenase 2 expression in human bladder carcinoma cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Roles of p38 and JNK mitogen-activated protein kinase pathways during cantharidin-induced apoptosis in U937 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Cantharidin, another natural toxin that inhibits the activity of serine/threonine protein phosphatases types 1 and 2A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Anticancer activity and protein phosphatase 1 and 2A inhibition of a new generation of cantharidin analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Cantharidin analogues: synthesis and evaluation of growth inhibition in a panel of selected tumour cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Structural basis of serine/threonine phosphatase inhibition by the archetypal small molecules cantharidin and norcantharidin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Protein phosphatase 2A as a potential target for anticancer therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

PP2A inhibitors induce apoptosis in pancreatic cancer cell line PANC-1 through persistent phosphorylation of IKKα and sustained activation of the NF-κB pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Cantharidin, a potent and selective PP2A inhibitor, induces an oxidative stress-independent growth inhibition of pancreatic cancer cells through G2/M cell-cycle arrest and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

The state of the art in anti-malarial drug discovery and development

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Artemisinin: the gifts from traditional Chinese medicine not only for malaria control but also for schistosomiasis control

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Synthesis and immunosuppressive activity of new artemisinin derivatives. 1. [12(beta or alpha)-Dihydroartemisininoxy]phen(ox)yl aliphatic acids and esters

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Anticancer activities of artemisinin and its bioactive derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Anti-cancer natural products isolated from chinese medicinal herbs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Artemisinin and its derivatives: a novel class of anti-malarial and anti-cancer agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Dihydroartemisinin is an inhibitor of ovarian cancer cell growth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Experimental Therapy of Hepatoma with Artemisinin and Its Derivatives: In vitro and In vivo Activity, Chemosensitization, and Mechanisms of Action

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Dihydroartemisinin induces apoptosis in HL-60 leukemia cells dependent of iron and p38 mitogen-activated protein kinase activation but independent of reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Dihydroartemisinin inhibits growth of pancreatic cancer cells in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Dihydroartemisinin upregulates death receptor 5 expression and cooperates with TRAIL to induce apoptosis in human prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

The anti-cancer activity of dihydroartemisinin is associated with induction of iron-dependent endoplasmic reticulum stress in colorectal carcinoma HCT116 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Dihydroartemisinin accelerates c-MYC oncoprotein degradation and induces apoptosis in c-MYC-overexpressing tumor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Dihydroartemisinin inactivates NF-kappaB and potentiates the anti-tumor effect of gemcitabine on pancreatic cancer both in vitro and in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Effect of artesunate on inhibiting proliferation and inducing apoptosis of SP2/0 myeloma cells through affecting NFkappaB p65.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Molecular modes of action of artesunate in tumor cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Anti-cancer effects of artesunate in a panel of chemoresistant neuroblastoma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Modulation of multidrug resistance by artemisinin, artesunate and dihydroartemisinin in K562/adr and GLC4/adr resistant cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Characterization of dihydroartemisinin-resistant colon carcinoma HCT116/R cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Artesunate induces oncosis-like cell death in vitro and has antitumor activity against pancreatic cancer xenografts in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Dihydroartemisinin induces apoptosis and sensitizes human ovarian cancer cells to carboplatin therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Heme mediates cytotoxicity from artemisinin and serves as a general anti-proliferation target

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Enhancement of cytotoxicity of artemisinins toward cancer cells by ferrous iron

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Factors determining sensitivity or resistance of tumor cell lines towards artesunate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Artemisinin blocks prostate cancer growth and cell cycle progression by disrupting Sp1 interactions with the cyclin-dependent kinase-4 (CDK4) promoter and inhibiting CDK4 gene expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Growth inhibitory effects of dihydroartemisinin on pancreatic cancer cells: involvement of cell cycle arrest and inactivation of nuclear factor-kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

The role of calcium, P38 MAPK in dihydroartemisinin-induced apoptosis of lung cancer PC-14 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Dihydroartemisinin induces apoptosis by a Bak-dependent intrinsic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

First evidence that the antimalarial drug artesunate inhibits invasion and in vivo metastasis in lung cancer by targeting essential extracellular proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Suppression of PMA-induced tumor cell invasion by dihydroartemisinin via inhibition of PKCalpha/Raf/MAPKs and NF-kappaB/AP-1-dependent mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Antimalarial dihydroartemisinin also inhibits angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Artemisinin reduces human melanoma cell migration by down-regulating alpha V beta 3 integrin and reducing metalloproteinase 2 production

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Danshen: an overview of its chemistry, pharmacology, pharmacokinetics, and clinical use

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Induction of apoptosis and inhibition of cell adhesive and invasive effects by tanshinone IIA in acute promyelocytic leukemia cells in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Potential anticancer activity of tanshinone IIA against human breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Growth inhibition and apoptosis induction by tanshinone IIA in human colon adenocarcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Cytotoxic Activities of Tanshinones Against Human Carcinoma Cell Lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Growth inhibition and apoptosis induction in human hepatoma cells by tanshinone II A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Growth inhibition and apoptosis induction of tanshinone II-A on human hepatocellular carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Cytotoxic effects of tanshinones from Salvia miltiorrhiza on doxorubicin-resistant human liver cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Tanshinone IIA activates calcium-dependent apoptosis signaling pathway in human hepatoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Tanshinone IIA induces mitochondria dependent apoptosis in prostate cancer cells in association with an inhibition of phosphoinositide 3-kinase/AKT pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

C/EBPβ and CHOP participate in tanshinone IIA-induced differentiation and apoptosis of acute promyelocytic leukemia cells in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Growth inhibition and induction of apoptosis and differentiation of tanshinone IIA in human glioma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Inhibitory effects of tanshinone II-A on invasion and metastasis of human colon carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Anti-angiogenic effect of Tanshinone IIA involves inhibition of matrix invasion and modification of MMP-2/TIMP-2 secretion in vascular endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Anticancer effects of tanshinone I in human non-small cell lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Tanshinone I suppresses growth and invasion of human breast cancer cells, MDA-MB-231, through regulation of adhesion molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Inactivation of PI3k/Akt signaling pathway and activation of caspase-3 are involved in tanshinone I-induced apoptosis in myeloid leukemia cells in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Reactive oxygen species-mediated kinase activation by dihydrotanshinone in tanshinones-induced apoptosis in HepG2 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Cryptotanshinone sensitizes DU145 prostate cancer cells to Fas(APO1/CD95)-mediated apoptosis through Bcl-2 and MAPK regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Triptolide and its expanding multiple pharmacological functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Immunosuppressant PG490 (triptolide) inhibits T-cell interleukin-2 expression at the level of purine-box/nuclear factor of activated T-cells and NF-kappaB transcriptional activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Triptolide, an inhibitor of the human heat shock response that enhances stress-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Triptolide and chemotherapy cooperate in tumor cell apoptosis. A role for the p53 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Triptolide binds covalently to a 90 kDa nuclear protein. Role of epoxides in binding and activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Triptolide is an inhibitor of RNA polymerase I and II-dependent transcription leading predominantly to down-regulation of short-lived mRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Triptolide (TPL) inhibits global transcription by inducing proteasome-dependent degradation of RNA polymerase II (Pol II).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Triptolide is a traditional Chinese medicine-derived inhibitor of polycystic kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

XPB, a subunit of TFIIH, is a target of the natural product triptolide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Increased accumulation of hypoxia-inducible factor-1α with reduced transcriptional activity mediates the antitumor effect of triptolide

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Pseudolaric acids: isolation, bioactivity and synthetic studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

The cytotoxic principles of Pseudolarix kaempferi: pseudolaric acid-A and -B and related derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Pseudolaric acid B, a novel microtubule-destabilizing agent that circumvents multidrug resistance phenotype and exhibits antitumor activity in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Microtubules as a target for anticancer drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Vinflunine: a new vision that may translate into antiangiogenic and antimetastatic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Protein tyrosine kinase, JNK, and ERK involvement in pseudolaric acid B-induced apoptosis of human breast cancer MCF-7 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Bcl-2 family proteins were involved in pseudolaric acid B-induced autophagy in murine fibrosarcoma L929 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Andrographolide and its analogues: versatile bioactive molecules for combating inflammation and cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Antihyperglycemic effect of andrographolide in streptozotocin-induced diabetic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Andrographolide attenuates inflammation by inhibition of NF-kappa B activation through covalent modification of reduced cysteine 62 of p50.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Andrographolide inhibits NF-kappaBeta activation and attenuates neointimal hyperplasia in arterial restenosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Andrographolide inhibits oral squamous cell carcinogenesis through NF-κB inactivation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Inhibition of tumor progression by naturally occurring terpenoids

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Oridonin, a diterpenoid purified from Rabdosia rubescens, inhibits the proliferation of cells from lymphoid malignancies in association with blockade of the NF-kappa B signal pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Downregulation of AP-1 gene expression is an initial event in the oridonin-mediated inhibition of colorectal cancer: studies in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Oridonin induces apoptosis via PI3K/Akt pathway in cervical carcinoma HeLa cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

NF-kappab facilitates oridonin-induced apoptosis and autophagy in HT1080 cells through a p53-mediated pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Molecular mechanisms of oridonin-induced apoptosis and autophagy in murine fibrosarcoma L929 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Reactive oxygen species contribute to oridonin-induced apoptosis and autophagy in human cervical carcinoma HeLa cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Anti-inflammatory compounds of plant origin. Part II. modulation of pro-inflammatory cytokines, chemokines and adhesion molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Celastrol, a potent antioxidant and anti-inflammatory drug, as a possible treatment for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Beneficial effect of tripterine on systemic lupus erythematosus induced by active chromatin in BALB/c mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Tripterine inhibits the expression of adhesion molecules in activated endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Celastrol inhibits pro-inflammatory cytokine secretion in Crohn's disease biopsies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Celastrol attenuates hypertension-induced inflammation and oxidative stress in vascular smooth muscle cells via induction of heme oxygenase-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Celastrol suppresses IFN-gamma-induced ICAM-1 expression and subsequent monocyte adhesiveness via the induction of heme oxygenase-1 in the HaCaT cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Celastrol suppresses angiogenesis-mediated tumor growth through inhibition of AKT/mammalian target of rapamycin pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Celastrol, a triterpene extracted from the Chinese "Thunder of God Vine," is a potent proteasome inhibitor and suppresses human prostate cancer growth in nude mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Celastrol: Molecular targets of Thunder God Vine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Cucurbitacins: specific insect attractants in Cucurbitaceae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Cucurbitacin: ancient compound shedding new light on cancer treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

The induction of G2/M cell-cycle arrest and apoptosis by cucurbitacin E is associated with increased phosphorylation of eIF2alpha in leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Cucurbitacin B induces differentiation, cell cycle arrest, and actin cytoskeletal alterations in myeloid leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Cucurbitacin B induces apoptosis and S phase cell cycle arrest in BEL-7402 human hepatocellular carcinoma cells and is effective via oral administration

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Cucurbitacin I inhibits tumorigenic ability and enhances radiochemosensitivity in nonsmall cell lung cancer-derived CD133-positive cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Histone deacetylase inhibitor valproic acid sensitizes B16F10 melanoma cells to cucurbitacin B treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Cucurbitacin I suppressed stem-like property and enhanced radiation-induced apoptosis in head and neck squamous carcinoma--derived CD44(+)ALDH1(+) cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Cucurbitacin I elicits anoikis sensitization, inhibits cellular invasion and in vivo tumor formation ability of nasopharyngeal carcinoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

STAT3alpha is oncogenic for endometrial carcinoma cells and mediates the oncogenic effects of autocrine human growth hormone.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Cucurbitacin B induces apoptosis by inhibition of the JAK/STAT pathway and potentiates antiproliferative effects of gemcitabine on pancreatic cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Cucurbitacin B, a novel in vivo potentiator of gemcitabine with low toxicity in the treatment of pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Combined antitumor activity of cucurbitacin B and docetaxel in laryngeal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Actin-aggregating cucurbitacins from Physocarpus capitatus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Direct interaction of Cucurbitacin E isolated from Alsomitra macrocarpa to actin filament

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Cucurbitacin B markedly inhibits growth and rapidly affects the cytoskeleton in glioblastoma multiforme.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Cucurbitacin I inhibits cell motility by indirectly interfering with actin dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Cucurbitacin IIa: a novel class of anti-cancer drug inducing non-reversible actin aggregation and inhibiting survivin independent of JAK2/STAT3 phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Cucurbitacin Q: a selective STAT3 activation inhibitor with potent antitumor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

JSI-124 (cucurbitacin I) inhibits Janus kinase-3/signal transducer and activator of transcription-3 signalling, downregulates nucleophosmin-anaplastic lymphoma kinase (ALK), and induces apoptosis in ALK-positive anaplastic large cell lymphoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Inhibition of constitutive activation of STAT3 by curcurbitacin-I (JSI-124) sensitized human B-leukemia cells to apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Inhibition of pancreatic cancer cell growth by cucurbitacin B through modulation of signal transducer and activator of transcription 3 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Anticancer and antiinflammatory activities of cucurbitacins from Cucurbita andreana

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Anti-inflammatory effects of a triterpenoid isolated from Wilbrandia ebracteata Cogn

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Anti-inflammatory activities of cucurbitacin E isolated from Citrullus lanatus var. citroides: role of reactive nitrogen species and cyclooxygenase enzyme inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Cytotoxic triterpenoides from Alismatis Rhizoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Alisol B, a novel inhibitor of the sarcoplasmic/endoplasmic reticulum Ca(2+) ATPase pump, induces autophagy, endoplasmic reticulum stress, and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Pharmacological evaluation of several major ingredients of Chinese herbal medicines in human hepatoma Hep3B cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Alisol B acetate, a triterpene from Alismatis rhizoma, induces Bax nuclear translocation and apoptosis in human hormone-resistant prostate cancer PC-3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Reversal of P-glycoprotein-mediated multidrug resistance by Alisol B 23-acetate

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Influence of traditional Chinese anti-inflammatory medicinal plants on leukocyte and platelet functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Pachymic acid impairs breast cancer cell invasion by suppressing nuclear factor-κB-dependent matrix metalloproteinase-9 expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Cytotoxic and anti-oxidant activities of lanostane-type triterpenes isolated from Poria cocos.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Induction of apoptosis in prostate cancer cells by pachymic acid from Poria cocos

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Cytotoxicity and DNA topoisomerases inhibitory activity of constituents from the sclerotium of Poria cocos

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

The role of carotenoids in the prevention of human pathologies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Cancer chemoprevention by carotenoids

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Lycopene and soy isoflavones in the treatment of prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Combinations of tomato and broccoli enhance antitumor activity in dunning r3327-h prostate adenocarcinomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Antioxidant and anti-proliferative properties of lycopene

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Lycopene inhibits angiogenesis both in vitro and in vivo by inhibiting MMP-2/uPA system through VEGFR2-mediated PI3K-Akt and ERK/p38 signaling pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

beta-Carotene induces apoptosis and up-regulates peroxisome proliferator-activated receptor gamma expression and reactive oxygen species production in MCF-7 cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Carotenoids reverse multidrug resistance in cancer cells by interfering with ABC-transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Apoptosis Induction in HL-60 Cells and Inhibition of Topoisomerase II by Triterpene Celastrol

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Gene expression signature-based chemical genomic prediction identifies a novel class of HSP90 pathway modulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

A novel Hsp90 inhibitor to disrupt Hsp90/Cdc37 complex against pancreatic cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Activation of heat shock and antioxidant responses by the natural product celastrol: transcriptional signatures of a thiol-targeted molecule.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

HSP90 inhibitor, celastrol, arrests human monocytic leukemia cell U937 at G0/G1 in thiol-containing agents reversible way

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Celastrol acts as a potent antimetastatic agent targeting beta1 integrin and inhibiting cell-extracellular matrix adhesion, in part via the p38 mitogen-activated protein kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Celastrol inhibits the growth of human glioma xenografts in nude mice through suppressing VEGFR expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

Inhibition of NF-κB activation through targeting IκB kinase by celastrol, a quinone methide triterpenoid

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.727395

10.1517/13543784.2012.727395

21 January 2018

Identifiers

DOI

1 reference

27 August 2017

1 reference