Force probing of individual molecules inside the living cell is now a reality (Q38053045)

27 August 2017

Force probing of individual molecules inside the living cell is now a reality (English)

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27 August 2017

Lene B Oddershede

1

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27 August 2017

1 November 2012

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27 August 2017

Nature Chemical Biology

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27 August 2017

8

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27 August 2017

11

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27 August 2017

879-886

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https://scigraph.springernature.com/pub.10.1038/nchembio.1082

27 August 2017

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cites work

Bead movement by single kinesin molecules studied with optical tweezers

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https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Kinesin hydrolyses one ATP per 8-nm step

21 January 2018

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Backtracking by single RNA polymerase molecules observed at near-base-pair resolution

21 January 2018

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Force and velocity measured for single molecules of RNA polymerase.

21 January 2018

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Single-molecule analysis of DNA uncoiling by a type II topoisomerase.

21 January 2018

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Following translation by single ribosomes one codon at a time.

21 January 2018

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Tracking topoisomerase activity at the single-molecule level

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Stretching DNA with optical tweezers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Unraveling the structure of DNA during overstretching by using multicolor, single-molecule fluorescence imaging

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Force-clamp spectroscopy monitors the folding trajectory of a single protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Effect of energy metabolism on protein motility in the bacterial outer membrane

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Dynein-mediated cargo transport in vivo. A switch controls travel distance

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Single cytoplasmic dynein molecule movements: characterization and comparison with kinesin

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Absolute in vivo translation rates of individual codons in Escherichia coli. The two glutamic acid codons GAA and GAG are translated with a threefold difference in rate.

21 January 2018

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21 January 2018

Atomic force microscope

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https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Optical trapping and manipulation of viruses and bacteria

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Force generation of organelle transport measured in vivo by an infrared laser trap

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Magnetic tweezers: micromanipulation and force measurement at the molecular level

21 January 2018

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Micro magnetic tweezers for nanomanipulation inside live cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Sensitive force technique to probe molecular adhesion and structural linkages at biological interfaces

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Single-molecule force spectroscopy: optical tweezers, magnetic tweezers and atomic force microscopy

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Recent advances in optical tweezers

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Light forces the pace: optical manipulation for biophotonics

21 January 2018

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Moving into the cell: single-molecule studies of molecular motors in complex environments.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

A polymeric molecular "handle" for multiple AFM-based single-molecule force measurements

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Three-dimensional optical control of individual quantum dots

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Quantitative optical trapping of single gold nanorods

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Large-scale orientation dependent heating from a single irradiated gold nanorod.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Dynamic strength of molecular adhesion bonds

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Forces and bond dynamics in cell adhesion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

The motion of a single molecule, the lambda-receptor, in the bacterial outer membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

A peptide tag system for facile purification and single-molecule immobilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Size-dependent endocytosis of gold nanoparticles studied by three-dimensional mapping of plasmonic scattering images

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Optical injection of mammalian cells using a microfluidic platform

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Chromosome micromanipulation. 3. Spindle fiber tension and the reorientation of mal-oriented chromosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Lateral Movements of Membrane Glycoproteins Restricted by Dynamic Cytoplasmic Barriers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Barriers for lateral diffusion of transferrin receptor in the plasma membrane as characterized by receptor dragging by laser tweezers: fence versus tether

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Compartmentalization of the erythrocyte membrane by the membrane skeleton: intercompartmental hop diffusion of band 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Sphingolipid-cholesterol rafts diffuse as small entities in the plasma membrane of mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Rapid hop diffusion of a G-protein-coupled receptor in the plasma membrane as revealed by single-molecule techniques

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Complex spatial distribution and dynamics of an abundant Escherichia coli outer membrane protein, LamB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Effect of antibiotics and antimicrobial peptides on single protein motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Diffusion of microspheres in sealed and open microarrays

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Measuring cell adhesion forces with the atomic force microscope at the molecular level

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Studying integrin-mediated cell adhesion at the single-molecule level using AFM force spectroscopy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Single-molecule atomic force microscopy reveals clustering of the yeast plasma-membrane sensor Wsc1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Developmental regulation of vesicle transport in Drosophila embryos: forces and kinetics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Probing dynein and kinesin stepping with mechanical manipulation in a living cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Consequences of motor copy number on the intracellular transport of kinesin-1-driven lipid droplets

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Force-velocity curves of motor proteins cooperating in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Casein kinase 2 reverses tail-independent inactivation of kinesin-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Visualizing myosin-actin interaction with a genetically-encoded fluorescent strain sensor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Velocity, processivity, and individual steps of single myosin V molecules in live cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

In vivo determination of fluctuating forces during endosome trafficking using a combination of active and passive microrheology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Micromechanics of human mitotic chromosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Insights into the micromechanical properties of the metaphase spindle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Force-generation and dynamic instability of microtubule bundles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Direct measurement of force generation by actin filament polymerization using an optical trap

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

DNA-coated AFM cantilevers for the investigation of cell adhesion and the patterning of live cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Simultaneous, coincident optical trapping and single-molecule fluorescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Construction and calibration of an optical trap on a fluorescence optical microscope.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Combining AFM and FRET for high resolution fluorescence microscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Investigation of perylene photonic wires by combined single-molecule fluorescence and atomic force microscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Sub-diffraction-limit imaging by stochastic optical reconstruction microscopy (STORM)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Fluorescence nanoscopy by ground-state depletion and single-molecule return

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Microscopy and its focal switch.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Single-molecule imaging reveals mechanisms of protein disruption by a DNA translocase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Synergistic action of RNA polymerases in overcoming the nucleosomal barrier.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Simultaneous micromanipulation in multiple planes using a self-reconstructing light beam

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Anomalous diffusion in living yeast cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

In vivo anomalous diffusion and weak ergodicity breaking of lipid granules.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Gold nanoparticles: enhanced optical trapping and sensitivity coupled with significant heating

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Wavelength dependence of cell cloning efficiency after optical trapping

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Stress response in Caenorhabditis elegans caused by optical tweezers: wavelength, power, and time dependence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Characterization of photodamage to Escherichia coli in optical traps.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Optical tweezers cause physiological damage to Escherichia coli and Listeria bacteria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Laser-induced heating in optical traps

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Direct measurements of heating by electromagnetically trapped gold nanoparticles on supported lipid bilayers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Interference model for back-focal-plane displacement detection in optical tweezers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Calibration of optical tweezers with positional detection in the back focal plane

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Active-passive calibration of optical tweezers in viscoelastic media.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Magnetic tweezers: a sensitive tool to study DNA and chromatin at the single-molecule level.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Magnetic torque tweezers: measuring torsional stiffness in DNA and RecA-DNA filaments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Optical torque wrench: angular trapping, rotation, and torque detection of quartz microparticles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Force probing surfaces of living cells to molecular resolution.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Biophysics of catch bonds

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Antitumour drugs impede DNA uncoiling by topoisomerase I

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Energy landscapes of receptor-ligand bonds explored with dynamic force spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Expanding the Optical Trapping Range of Gold Nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

Five challenges to bringing single-molecule force spectroscopy into living cells

21 January 2018

1 reference

12 December 2020

Reversible unfolding of individual titin immunoglobulin domains by AFM

1 reference

12 December 2020

Discrete interactions in cell adhesion measured by single-molecule force spectroscopy

1 reference

12 December 2020

Optical trapping of metallic Rayleigh particles

1 reference

12 December 2020

Quantifying how DNA stretches, melts and changes twist under tension

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

7 January 2021

inferred from DOI database lookup

Dynamic holographic optical tweezers

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1082

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NCHEMBIO.1082

1 reference

PubMed ID

23076067

Dimensions Publication ID

27 August 2017

0 references

1 reference

PubMed ID

23076067